Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q4 2022
Institutional positions in Ionis Pharmaceuticals Inc as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 339
- −4 vs. Q3 2022
- Shares held
- 130.6M
- +4.77M (+3.8%) vs. Q3 2022
- Total value
- $4.93B
- −$630.7M (−11.3%) vs. Q3 2022
- New holders
- 50
- 115 more added
- Sold out
- 54
- 107 more reduced
7 institutions that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q4 2022
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q3 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Neuberger Berman Group LLC | 10,985 | $414.9K | 0.00% | −214−1.9% | Reduced |
| Maryland State Retirement & Pension System | 10,950 | $413.6K | 0.01% | +10,950 | New |
| Advisor Group Holdings, Inc. | 10,829 | $408.3K | 0.00% | −706−6.1% | Reduced |
| Hanseatic Management Services Inc | 10,811 | $408.0K | 1.03% | −182−1.7% | Reduced |
| Vontobel Holding Ltd. | 10,929 | $405.7K | 0.00% | −353−3.1% | Reduced |
| Verition Fund Management LLC | 10,512 | $397.0K | 0.01% | +10,512 | New |
| Oppenheimer Asset Management Inc. | 10,369 | $391.6K | 0.01% | −465−4.3% | Reduced |
| Martingale Asset Management L P | 10,361 | $391.3K | 0.01% | +648+6.7% | Added |
| Waddell & Associates, LLC | 10,042 | $379.3K | 0.06% | 00.0% | Unchanged |
| Grantham, Mayo, Van Otterloo & Co. LLC | 9,700 | $366.4K | 0.00% | +9,700 | New |
| Cambridge Investment Research Advisors, Inc. | 9,555 | $361.0K | 0.00% | −1,367−12.5% | Reduced |
| Captrust Financial Advisors | 9,528 | $359.9K | 0.00% | +9,528 | New |
| The PNC Financial Services Group, Inc. | 9,267 | $350.0K | 0.00% | −562−5.7% | Reduced |
| National Asset Management, Inc. | 8,736 | $330.0K | 0.01% | +1,404+19.1% | Added |
| Wrapmanager Inc | 8,499 | $321.0K | 0.10% | −334−3.8% | Reduced |
| MetLife Investment Management | 8,082 | $305.3K | 0.00% | −205−2.5% | Reduced |
| Horizon Kinetics Asset Management LLC | 8,000 | $302.2K | 0.00% | 00.0% | Unchanged |
| Nicollet Investment Management, Inc. | 7,938 | $300.0K | 0.17% | −570−6.7% | Reduced |
| Virtus ETF Advisers LLC | 7,900 | $298.4K | 0.16% | +871+12.4% | Added |
| Commerce Bank | 7,742 | $292.4K | 0.00% | +311+4.2% | Added |
| Northeast Financial Consultants Inc | 7,740 | $292.3K | 0.02% | 00.0% | Unchanged |
| ETF Managers Group, LLC | 7,649 | $288.9K | 0.01% | +7,649 | New |
| Utah Retirement Systems | 7,500 | $283.3K | 0.00% | 00.0% | Unchanged |
| AQR Capital Management LLC | 7,569 | $282.0K | 0.00% | −141−1.8% | Reduced |
| Tower Research Capital LLC (TRC) | 7,272 | $275.0K | 0.01% | −4,483−38.1% | Reduced |
| Tanaka Capital Management Inc | 7,112 | $269.0K | 0.85% | 00.0% | Unchanged |
| Calamos Advisors LLC | 7,026 | $265.4K | 0.00% | −10,093−59.0% | Reduced |
| Stephens Inc | 7,003 | $264.5K | 0.01% | −2,122−23.3% | Reduced |
| Sherbrooke Park Advisers LLC | 7,000 | $264.4K | 0.19% | +7,000 | New |
| Northwestern Mutual Wealth Management Co | 6,917 | $261.3K | 0.00% | −330−4.6% | Reduced |
| Baird Financial Group, Inc. | 6,893 | $261.0K | 0.00% | +121+1.8% | Added |
| Oversea-Chinese Banking CORP Ltd | 6,840 | $258.0K | 0.01% | +6,840 | New |
| Stonegate Investment Group, LLC | 6,807 | $257.1K | 0.01% | 00.0% | Unchanged |
| MQS Management LLC | 6,547 | $247.3K | 0.17% | +6,547 | New |
| Perkins Capital Management Inc | 6,400 | $242.0K | 0.26% | 00.0% | Unchanged |
| First Republic Investment Management, Inc. | 6,209 | $234.5K | 0.00% | −461−6.9% | Reduced |
| IFP Advisors, Inc | 4,838 | $233.0K | 0.01% | −951−16.4% | Reduced |
| JustInvest LLC | 6,159 | $232.6K | 0.01% | +950+18.2% | Added |
| Seven Eight Capital, LP | 5,990 | $226.2K | 0.06% | +700+13.2% | Added |
| Cetera Advisor Networks LLC | 5,672 | $214.2K | 0.00% | +5,672 | New |
| Regions Financial Corp | 5,346 | $202.0K | 0.00% | 00.0% | Unchanged |
| Alpha Paradigm Partners, LLC | 5,335 | $202.0K | 0.08% | +5,335 | New |
| Beaird Harris Wealth Management, LLC | 5,062 | $191.2K | 0.04% | +62+1.2% | Added |
| Sectoral Asset Management Inc | 4,450 | $168.1K | 0.03% | 00.0% | Unchanged |
| Simplex Trading, LLC | 4,370 | $165.0K | 0.01% | +4,370 | New |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 4,269 | $160.4K | 0.00% | −439−9.3% | Reduced |
| Lazard Asset Management LLC | 3,723 | $139.0K | 0.00% | −322−8.0% | Reduced |
| Amundi | 3,593 | $136.4K | 0.00% | +3,593 | New |
| Aquatic Capital Management LLC | 3,200 | $121.0K | 0.01% | −22,300−87.5% | Reduced |
| Chiron Investment Management, LLC | 3,173 | $119.8K | 0.03% | 00.0% | Unchanged |
| Rockefeller Capital Management L.P. | 2,581 | $97.0K | 0.00% | 00.0% | Unchanged |
| Fifth Third Bancorp | 2,500 | $94.4K | 0.00% | 00.0% | Unchanged |
| American International Group, Inc. | 2,106 | $79.5K | 0.00% | −47−2.2% | Reduced |
| First Manhattan Co | 1,975 | $74.6K | 0.00% | 00.0% | Unchanged |
| Itau Unibanco Holding S.A. | 1,848 | $69.8K | 0.00% | +10+0.5% | Added |
| CWM, LLC | 1,837 | $69.0K | 0.00% | −126−6.4% | Reduced |
| Twin Lakes Capital Management, LLC | 1,500 | $56.7K | 0.04% | 00.0% | Unchanged |
| China Universal Asset Management Co., Ltd. | 1,443 | $54.5K | 0.02% | +114+8.6% | Added |
| New England Capital Financial Advisors LLC | 1,300 | $53.0K | 0.04% | +1,300 | New |
| KBC Group NV | 1,378 | $52.0K | 0.00% | 00.0% | Unchanged |
| Walleye Trading LLC | 1,316 | $49.7K | 0.00% | +1,316 | New |
| GWM Advisors LLC | 1,317 | $49.4K | 0.00% | +1,317 | New |
| Kistler-Tiffany Companies, LLC | 1,281 | $48.4K | 0.01% | 00.0% | Unchanged |
| Banque Cantonale Vaudoise | 1,279 | $48.0K | 0.00% | +879+219.7% | Added |
| Harbour Investments, Inc. | 1,210 | $45.7K | 0.00% | −50−4.0% | Reduced |
| Romano Brothers and Company | 1,148 | $43.4K | 0.01% | +1,148 | New |
| United Community Bank | 1,131 | $42.7K | 0.04% | +5+0.4% | Added |
| Ronald Blue Trust, Inc. | 849 | $38.0K | 0.00% | +174+25.8% | Added |
| Heritage Wealth Management, LLC | 900 | $34.0K | 0.00% | +224+33.1% | Added |
| Archer Investment Corp | 850 | $32.1K | 0.01% | 00.0% | Unchanged |
| Allworth Financial LP | 797 | $30.1K | 0.00% | 00.0% | Unchanged |
| Institutional & Family Asset Management, LLC | 774 | $29.2K | 0.00% | −12−1.5% | Reduced |
| Glassman Wealth Services | 733 | $27.7K | 0.01% | −6−0.8% | Reduced |
| Altshuler Shaham Ltd | 695 | $26.3K | 0.00% | −690−49.8% | Reduced |
| Zullo Investment Group, Inc. | 682 | $25.8K | 0.02% | 00.0% | Unchanged |
| Parallel Advisors, LLC | 671 | $25.3K | 0.00% | −51−7.1% | Reduced |
| Washington Trust Advisors, Inc. | 660 | $24.9K | 0.00% | −865−56.7% | Reduced |
| Advisory Services Network, LLC | 616 | $23.3K | 0.00% | +616 | New |
| Belpointe Asset Management LLC | 608 | $23.0K | 0.00% | +608 | New |
| Laurel Wealth Advisors LLC | 600 | $22.7K | 0.01% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 571 | $22.0K | 0.00% | +43+8.1% | Added |
| AlphaMark Advisors, LLC | 550 | $21.0K | 0.01% | 00.0% | Unchanged |
| Leonteq Securities AG | 523 | $19.8K | 0.00% | +209+66.6% | Added |
| Riggs Asset Managment Co. Inc. | 500 | $18.9K | 0.01% | −497−49.8% | Reduced |
| Riverview Trust Co | 476 | $18.0K | 0.02% | 00.0% | Unchanged |
| Advent Capital Management | 464 | $17.5K | 0.00% | 00.0% | Unchanged |
| Geneos Wealth Management Inc. | 400 | $15.1K | 0.00% | 00.0% | Unchanged |
| Global Trust Asset Management, LLC | 399 | $15.1K | 0.01% | 00.0% | Unchanged |
| Loomis Sayles & Co L P | 344 | $13.0K | 0.00% | +344 | New |
| Whittier Trust Co of Nevada Inc | 341 | $12.9K | 0.00% | 00.0% | Unchanged |
| Steward Partners Investment Advisory, LLC | 313 | $11.8K | 0.00% | −23−6.8% | Reduced |
| Quadrant Capital Group LLC | 247 | $9.33K | 0.00% | −50−16.8% | Reduced |
| Covestor Ltd | 246 | $9.00K | 0.01% | −11−4.3% | Reduced |
| Signaturefd, LLC | 231 | $8.72K | 0.00% | −17−6.9% | Reduced |
| Ci Investments Inc. | 202 | $8.00K | 0.00% | +194+2,425.0% | Added |
| Insight Financial Services | 200 | $7.55K | 0.01% | 00.0% | Unchanged |
| AllSquare Wealth Management LLC | 198 | $7.48K | 0.01% | 00.0% | Unchanged |
| Carolinas Wealth Consulting LLC | 187 | $7.06K | 0.00% | 00.0% | Unchanged |
| Clearstead Advisors, LLC | 185 | $6.99K | 0.00% | 00.0% | Unchanged |
| Farther Finance Advisors, LLC | 159 | $6.00K | 0.00% | +159 | New |