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Ionis Pharmaceuticals Inc

IONS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000874015

In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.

Q4 2022 vs. Q3 2022

How the institutions holding Ionis Pharmaceuticals Inc changed between Q3 2022 and Q4 2022.

All holders in Q4 2022All holders in Q3 2022

13F holders of IONS: Q3 2022 compared with Q4 2022
MeasureQ3 2022Of which not filed for Q4 2022Q4 2022Change
Holders3507339−4
Shares126.4M492.6K130.6M+4.77M (+3.8%)
Value$5.59B$21.8M$4.93B−$630.7M (−11.3%)

7 institutions that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so the changes leave them out.

New holders (50)

Institutions that held Ionis Pharmaceuticals Inc at the end of Q4 2022 but not at the end of Q3 2022.

Institutions new to IONS in Q4 2022
InstitutionSharesValue% of portfolio
Deep Track Capital, LP1,205,773$45.5M1.99%
CI Private Wealth, LLC302,677$11.4M0.04%
Jefferies Financial Group Inc.197,009$7.44M0.13%
M28 Capital Management LP126,300$4.77M4.55%
Alberta Investment Management Corp101,426$3.83M0.03%
Public Sector Pension Investment Board98,000$3.70M0.03%
Canada Pension Plan Investment Board72,900$2.75M0.00%
Magnetar Financial LLC34,597$1.31M0.02%
Bank of Nova Scotia31,000$1.17M0.00%
Voloridge Investment Management, LLC30,709$1.16M0.01%
Edgestream Partners, L.P.27,393$1.03M0.12%
Pinebridge Investments, L.P.26,959$1.02M0.01%
Dynamic Technology Lab Private Ltd25,580$966.0K0.10%
Cantor Fitzgerald, L. P.22,880$864.0K0.02%
American Trust15,970$603.2K0.06%
Group One Trading, L.P.15,463$584.0K0.02%
Quantedge Capital Pte Ltd15,100$570.3K0.19%
Campbell & CO Investment Adviser LLC15,018$567.2K0.14%
Westmount Partners, LLC13,462$508.5K0.26%
Bleakley Financial Group, LLC13,184$498.0K0.02%
Caption Management, LLC13,000$491.0K0.08%
Illinois Municipal Retirement Fund11,866$448.0K0.01%
Maryland State Retirement & Pension System10,950$413.6K0.01%
Verition Fund Management LLC10,512$397.0K0.01%
Grantham, Mayo, Van Otterloo & Co. LLC9,700$366.4K0.00%
Captrust Financial Advisors9,528$359.9K0.00%
ETF Managers Group, LLC7,649$288.9K0.01%
Sherbrooke Park Advisers LLC7,000$264.4K0.19%
Oversea-Chinese Banking CORP Ltd6,840$258.0K0.01%
MQS Management LLC6,547$247.3K0.17%
Cetera Advisor Networks LLC5,672$214.2K0.00%
Alpha Paradigm Partners, LLC5,335$202.0K0.08%
Simplex Trading, LLC4,370$165.0K0.01%
Amundi3,593$136.4K0.00%
New England Capital Financial Advisors LLC1,300$53.0K0.04%
Walleye Trading LLC1,316$49.7K0.00%
GWM Advisors LLC1,317$49.4K0.00%
Romano Brothers and Company1,148$43.4K0.01%
Advisory Services Network, LLC616$23.3K0.00%
Belpointe Asset Management LLC608$23.0K0.00%
Loomis Sayles & Co L P344$13.0K0.00%
Farther Finance Advisors, LLC159$6.00K0.00%
Affiance Financial, LLC100$3.78K0.00%
Colonial Trust Co82$3.06K0.00%
Baker Avenue Asset Management, LP77$2.91K0.00%
Johnson Midwest Financial, LLC59$2.00K0.01%
Cornerstone Planning Group LLC45$1.83K0.00%
Concord Wealth Partners36$1.36K0.00%
Bessemer Group Inc25$1.00K0.00%
CoreCap Advisors, LLC26$9820.00%

Sold out (54)

Institutions that held Ionis Pharmaceuticals Inc at the end of Q3 2022 and filed for Q4 2022 without it.

Institutions that sold out of IONS in Q4 2022
InstitutionShares, Q3 2022Value, Q3 2022
Woodline Partners LP406,483$18.0M
Jump Financial, LLC86,602$3.83M
Alps Advisors Inc77,480$3.43M
Liontrust Investment Partners LLP72,269$3.20M
UBS Oconnor LLC54,497$2.41M
Graham Capital Management, L.P.53,717$2.38M
Brookstone Capital Management38,035$1.75M
EAM Investors, LLC28,396$1.26M
Twin Tree Management, LP23,517$1.04M
Capital Fund Management S.A.23,023$1.02M
Ziegler Capital Management, LLC20,659$914.0K
Acadian Asset Management LLC20,390$898.0K
Knowledge Leaders Capital, LLC19,360$856.0K
AlphaCrest Capital Management LLC14,770$653.0K
SG Americas Securities, LLC12,698$562.0K
Shell Asset Management Co11,265$498.0K
Occudo Quantitative Strategies LP10,766$476.0K
Two Sigma Securities, LLC8,670$383.0K
Brandywine Managers, LLC8,460$374.0K
Independent Financial Group, LLC8,325$368.2K
Quantbot Technologies LP8,106$358.0K
Quantamental Technologies LLC6,899$305.0K
Truist Financial Corp6,420$284.0K
NewEdge Wealth, LLC5,854$259.0K
Prelude Capital Management, LLC5,341$236.0K
M&T Bank Corp5,168$230.0K
CIBC Asset Management Inc5,203$230.0K
Prudential Financial Inc5,098$226.0K
Prospera Financial Services Inc5,095$226.0K
Buckingham Strategic Wealth, LLC5,092$225.0K
Archford Capital Strategies, LLC5,042$223.0K
Ieq Capital, LLC4,983$220.0K
Mitchell & Pahl Private Wealth, LLC4,866$215.0K
Cornercap Investment Counsel Inc4,703$208.0K
Toroso Investments, LLC4,667$206.0K
Caldwell Trust Co4,000$176.9K
Point72 Hong Kong Ltd3,740$165.0K
Icon Wealth Advisors, LLC2,884$128.0K
DuPont Capital Management Corp2,769$122.0K
State of Wyoming1,338$59.0K
Almanack Investment Partners, LLC.1,000$44.0K
Wolff Wiese Magana LLC910$40.0K
Ellis Investment Partners, LLC500$22.0K
Assetmark, Inc250$11.0K
Trustcore Financial Services, LLC228$10.0K
Meeder Asset Management Inc186$8.00K
GPS Wealth Strategies Group, LLC119$5.00K
TD Waterhouse Canada Inc.100$4.50K
Cutler Group LP100$4.00K
Cranbrook Wealth Management, LLC25$1.00K
Ellevest, Inc.32$1.00K
BDO Wealth Advisors, LLC33$1.00K
EdgeRock Capital LLC25$1.00K
Aspire Private Capital, LLC8$0

Not filed for Q4 2022 yet (7)

Institutions that held Ionis Pharmaceuticals Inc at the end of Q3 2022 and haven't filed a 13F for Q4 2022. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding IONS in Q3 2022 that haven't filed for Q4 2022
InstitutionShares, Q3 2022Value, Q3 2022
Dowling & Yahnke LLC302,571$13.4M
Jefferies Group LLC105,566$4.67M
Eaton Vance Management70,682$3.13M
Strategic Wealth Advisors Group, LLC12,729$563.0K
Wipfli Financial Advisors LLC,619$27.0K
American Portfolios Advisors300$13.3K
Monolith Advisors133$6.00K