Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q2 2022
Institutional positions in Ionis Pharmaceuticals Inc as of Jun 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 351
- +22 vs. Q1 2022
- Shares held
- 124.6M
- +27.5K (0.0%) vs. Q1 2022
- Total value
- $4.61B
- −$315.6K (0.0%) vs. Q1 2022
- New holders
- 53
- 89 more added
- Sold out
- 31
- 130 more reduced
4 institutions that held it in Q1 2022 haven't filed for Q2 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q2 2022
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q1 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| SEI Investments Co | 10,626 | $392.0K | 0.00% | −392−3.6% | Reduced |
| Waddell & Associates, LLC | 10,042 | $372.0K | 0.08% | +10,042 | New |
| The PNC Financial Services Group, Inc. | 9,982 | $370.0K | 0.00% | +320+3.3% | Added |
| Maryland State Retirement & Pension System | 9,956 | $369.0K | 0.01% | 00.0% | Unchanged |
| Rockefeller Capital Management L.P. | 9,851 | $363.0K | 0.00% | −1,405−12.5% | Reduced |
| Bridgewater Associates, LP | 9,779 | $362.0K | 0.00% | +2,578+35.8% | Added |
| Brown Advisory Inc | 9,630 | $357.0K | 0.00% | +9,630 | New |
| Wrapmanager Inc | 9,551 | $354.0K | 0.11% | −163−1.7% | Reduced |
| Verition Fund Management LLC | 9,531 | $353.0K | 0.01% | +9,531 | New |
| HighTower Advisors, LLC | 9,488 | $349.0K | 0.00% | +376+4.1% | Added |
| Delphia (USA) Inc. | 9,311 | $345.0K | 0.24% | +3,095+49.8% | Added |
| Bayesian Capital Management, LP | 9,063 | $336.0K | 0.06% | +9,063 | New |
| Brandywine Managers, LLC | 8,460 | $313.0K | 0.77% | 00.0% | Unchanged |
| Nicollet Investment Management, Inc. | 8,442 | $313.0K | 0.17% | +173+2.1% | Added |
| National Asset Management, Inc. | 8,402 | $312.0K | 0.01% | −696−7.7% | Reduced |
| Corton Capital Inc. | 8,398 | $311.0K | 0.29% | −411−4.7% | Reduced |
| MetLife Investment Management | 8,287 | $306.8K | 0.00% | −292−3.4% | Reduced |
| Independent Financial Group, LLC | 8,125 | $300.8K | 0.03% | −365−4.3% | Reduced |
| Horizon Kinetics Asset Management LLC | 8,000 | $296.0K | 0.01% | 00.0% | Unchanged |
| Northeast Financial Consultants Inc | 7,740 | $287.0K | 0.02% | 00.0% | Unchanged |
| Toroso Investments, LLC | 7,607 | $282.0K | 0.01% | +2,030+36.4% | Added |
| IFP Advisors, Inc | 5,789 | $279.0K | 0.01% | −3,373−36.8% | Reduced |
| Commerce Bank | 7,431 | $275.0K | 0.00% | −567−7.1% | Reduced |
| Martingale Asset Management L P | 7,405 | $275.0K | 0.01% | 00.0% | Unchanged |
| Prelude Capital Management, LLC | 7,428 | $275.0K | 0.01% | +7,428 | New |
| Utah Retirement Systems | 7,400 | $274.0K | 0.00% | 00.0% | Unchanged |
| American Century Companies Inc | 7,355 | $272.0K | 0.00% | +1,761+31.5% | Added |
| NewEdge Wealth, LLC | 7,315 | $271.0K | 0.01% | +7,315 | New |
| Tanaka Capital Management Inc | 7,112 | $263.0K | 0.86% | −1,435−16.8% | Reduced |
| Stonegate Investment Group, LLC | 7,055 | $261.0K | 0.01% | +681+10.7% | Added |
| Northwestern Mutual Wealth Management Co | 6,979 | $258.0K | 0.00% | +4,716+208.4% | Added |
| Virtus ETF Advisers LLC | 6,925 | $256.0K | 0.09% | −5,371−43.7% | Reduced |
| Baird Financial Group, Inc. | 6,897 | $255.0K | 0.00% | −3,396−33.0% | Reduced |
| Aristides Capital LLC | 6,891 | $255.0K | 0.20% | 00.0% | Unchanged |
| Great West Life Assurance Co | 6,720 | $248.0K | 0.00% | +115+1.7% | Added |
| Old Mission Capital LLC | 6,582 | $244.0K | 0.01% | +6,582 | New |
| Two Sigma Securities, LLC | 6,573 | $243.0K | 0.04% | +6,573 | New |
| First Foundation Advisors | 6,412 | $237.0K | 0.01% | −22,718−78.0% | Reduced |
| Walleye Capital LLC | 6,369 | $236.0K | 0.01% | +6,369 | New |
| Parametrica Management Ltd | 6,165 | $228.0K | 0.25% | +6,165 | New |
| JustInvest LLC | 6,083 | $225.0K | 0.01% | +487+8.7% | Added |
| First Republic Investment Management, Inc. | 6,016 | $223.0K | 0.00% | −90−1.5% | Reduced |
| Berkshire Asset Management LLC | 5,596 | $207.0K | 0.01% | −4,143−42.5% | Reduced |
| Lazard Asset Management LLC | 5,625 | $207.0K | 0.00% | +568+11.2% | Added |
| Allspring Global Investments Holdings, LLC | 5,519 | $204.0K | 0.00% | −81,766−93.7% | Reduced |
| M&T Bank Corp | 5,501 | $204.0K | 0.00% | +5,501 | New |
| Gsa Capital Partners LLP | 5,475 | $203.0K | 0.03% | +5,475 | New |
| Seven Eight Capital, LP | 5,457 | $202.0K | 0.08% | −10,339−65.5% | Reduced |
| Mercer Global Advisors Inc | 5,396 | $200.0K | 0.00% | +5,396 | New |
| Group One Trading, L.P. | 4,654 | $172.0K | 0.00% | +4,654 | New |
| Sectoral Asset Management Inc | 4,450 | $165.0K | 0.03% | +4,450 | New |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 4,394 | $163.0K | 0.00% | −2,972−40.3% | Reduced |
| Caldwell Trust Co | 4,000 | $148.1K | 0.02% | 00.0% | Unchanged |
| Geneos Wealth Management Inc. | 3,435 | $130.0K | 0.01% | −1,628−32.2% | Reduced |
| NuWave Investment Management, LLC | 3,434 | $127.0K | 0.17% | +3,434 | New |
| Canada Pension Plan Investment Board | 3,124 | $116.0K | 0.00% | −6,487−67.5% | Reduced |
| Semmax Financial Advisors Inc. | 2,327 | $107.0K | 0.04% | −247−9.6% | Reduced |
| Itau Unibanco Holding S.A. | 2,651 | $98.0K | 0.00% | −140−5.0% | Reduced |
| Fifth Third Bancorp | 2,500 | $93.0K | 0.00% | −214−7.9% | Reduced |
| American International Group, Inc. | 2,147 | $79.0K | 0.00% | −421−16.4% | Reduced |
| First Manhattan Co | 1,975 | $73.0K | 0.00% | +775+64.6% | Added |
| Leonteq Securities AG | 1,954 | $72.3K | 0.00% | −273−12.3% | Reduced |
| CWM, LLC | 1,719 | $64.0K | 0.00% | +165+10.6% | Added |
| Washington Trust Advisors, Inc. | 1,637 | $61.0K | 0.01% | −394−19.4% | Reduced |
| Tower Research Capital LLC (TRC) | 1,430 | $53.0K | 0.00% | −7,298−83.6% | Reduced |
| Captrust Financial Advisors | 1,429 | $53.0K | 0.00% | +249+21.1% | Added |
| KBC Group NV | 1,378 | $51.0K | 0.00% | −6,661−82.9% | Reduced |
| Kistler-Tiffany Companies, LLC | 1,281 | $47.0K | 0.01% | 00.0% | Unchanged |
| Harbour Investments, Inc. | 1,260 | $47.0K | 0.00% | +1,260 | New |
| International Biotechnology Trust PLC | 1,703 | $46.1K | 0.91% | −152,385−98.9% | Reduced |
| Quantbot Technologies LP | 1,200 | $44.0K | 0.00% | +1,200 | New |
| Wolff Wiese Magana LLC | 1,074 | $40.0K | 0.03% | −57−5.0% | Reduced |
| United Community Bank | 1,046 | $38.7K | 0.04% | +79+8.2% | Added |
| Riggs Asset Managment Co. Inc. | 997 | $37.0K | 0.02% | 00.0% | Unchanged |
| Heritage Financial Services, LLC | 900 | $33.0K | 0.02% | +900 | New |
| Archer Investment Corp | 850 | $31.5K | 0.01% | 00.0% | Unchanged |
| Altshuler Shaham Ltd | 834 | $31.0K | 0.00% | +834 | New |
| Zullo Investment Group, Inc. | 817 | $30.0K | 0.02% | 00.0% | Unchanged |
| Institutional & Family Asset Management, LLC | 746 | $28.0K | 0.00% | 00.0% | Unchanged |
| Glassman Wealth Services | 739 | $27.0K | 0.01% | −83−10.1% | Reduced |
| Allworth Financial LP | 739 | $27.0K | 0.00% | 00.0% | Unchanged |
| Parallel Advisors, LLC | 724 | $27.0K | 0.00% | +8+1.1% | Added |
| Heritage Wealth Management, LLC | 676 | $25.0K | 0.01% | 00.0% | Unchanged |
| Ronald Blue Trust, Inc. | 675 | $25.0K | 0.00% | +675 | New |
| Laurel Wealth Advisors LLC | 600 | $22.0K | 0.01% | 00.0% | Unchanged |
| AlphaMark Advisors, LLC | 555 | $21.0K | 0.01% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 528 | $20.0K | 0.00% | +116+28.2% | Added |
| Elequin Capital LP | 532 | $20.0K | 0.00% | +172+47.8% | Added |
| Ellis Investment Partners, LLC | 500 | $18.0K | 0.00% | −63−11.2% | Reduced |
| Riverview Trust Co | 476 | $18.0K | 0.02% | 00.0% | Unchanged |
| Whittier Trust Co of Nevada Inc | 405 | $15.0K | 0.00% | 00.0% | Unchanged |
| Global Trust Asset Management, LLC | 399 | $15.0K | 0.01% | 00.0% | Unchanged |
| Banque Cantonale Vaudoise | 400 | $15.0K | 0.00% | 00.0% | Unchanged |
| Covestor Ltd | 366 | $14.0K | 0.01% | −11−2.9% | Reduced |
| Nisa Investment Advisors, LLC | 359 | $13.0K | 0.00% | 00.0% | Unchanged |
| Steward Partners Investment Advisory, LLC | 362 | $13.0K | 0.00% | 00.0% | Unchanged |
| American Portfolios Advisors | 300 | $11.1K | 0.00% | 00.0% | Unchanged |
| Spire Wealth Management | 306 | $11.0K | 0.00% | −63−17.1% | Reduced |
| Hall Laurie J Trustee | 270 | $10.0K | 0.00% | 00.0% | Unchanged |
| Quadrant Capital Group LLC | 263 | $10.0K | 0.00% | −4−1.5% | Reduced |