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Ionis Pharmaceuticals Inc

IONS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000874015

In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.

13F holders, Q2 2022

Institutional positions in Ionis Pharmaceuticals Inc as of Jun 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
351
+22 vs. Q1 2022
Shares held
124.6M
+27.5K (0.0%) vs. Q1 2022
Total value
$4.61B
−$315.6K (0.0%) vs. Q1 2022
New holders
53
89 more added
Sold out
31
130 more reduced

4 institutions that held it in Q1 2022 haven't filed for Q2 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2022: 351 institutions
Q1 2021: 365 institutionsQ2 2021: 338 institutionsQ3 2021: 326 institutionsQ4 2021: 341 institutionsQ1 2022: 333 institutionsQ2 2022: 351 institutionsQ3 2022: 350 institutionsQ4 2022: 339 institutionsQ1 2023: 315 institutionsQ2 2023: 305 institutionsQ3 2023: 312 institutionsQ4 2023: 365 institutionsQ1 2024: 361 institutionsQ2 2024: 357 institutionsQ3 2024: 354 institutionsQ4 2024: 356 institutionsQ1 2025: 344 institutionsQ2 2025: 363 institutionsQ3 2025: 437 institutionsQ4 2025: 494 institutionsQ1 2026: 497 institutionsQ2 2026: 515 institutions
Value heldQ2 2022: $4.61B
Q1 2021: $5.55BQ2 2021: $4.96BQ3 2021: $4.08BQ4 2021: $3.75BQ1 2022: $4.63BQ2 2022: $4.61BQ3 2022: $5.59BQ4 2022: $4.93BQ1 2023: $4.69BQ2 2023: $5.60BQ3 2023: $6.35BQ4 2023: $7.21BQ1 2024: $6.17BQ2 2024: $6.83BQ3 2024: $6.31BQ4 2024: $5.61BQ1 2025: $5.03BQ2 2025: $6.67BQ3 2025: $11.0BQ4 2025: $13.5BQ1 2026: $13.0BQ2 2026: $14.3B
Institutions holding IONS and their total value by quarter
QuarterHoldersValue
Q2 2026515$14.3B
Q1 2026497$13.0B
Q4 2025494$13.5B
Q3 2025437$11.0B
Q2 2025363$6.67B
Q1 2025344$5.03B
Q4 2024356$5.61B
Q3 2024354$6.31B
Q2 2024357$6.83B
Q1 2024361$6.17B
Q4 2023365$7.21B
Q3 2023312$6.35B
Q2 2023305$5.60B
Q1 2023315$4.69B
Q4 2022339$4.93B
Q3 2022350$5.59B
Q2 2022351$4.61B
Q1 2022333$4.63B
Q4 2021341$3.75B
Q3 2021326$4.08B
Q2 2021338$4.96B
Q1 2021365$5.55B

Institutions, Q2 2022

Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q1 2022.

Institutions holding IONS in Q2 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Huntington National Bank1$00.00%00.0%Unchanged
Valley National Advisers Inc11$00.00%00.0%Unchanged
Ci Investments Inc.8$00.00%00.0%Unchanged
Retirement Group, LLC11$00.00%00.0%Unchanged
Aspire Private Capital, LLC8$00.00%00.0%Unchanged
Hexagon Capital Partners LLC9$00.00%00.0%Unchanged
Fairfield, Bush & Co.4$00.00%+4New
Patriot Financial Group Insurance Agency, LLC18$1.00K0.00%−481−96.4%Reduced
TCI Wealth Advisors, Inc.35$1.00K0.00%00.0%Unchanged
Focused Wealth Management, Inc16$1.00K0.00%00.0%Unchanged
Cranbrook Wealth Management, LLC25$1.00K0.00%00.0%Unchanged
First Bank & Trust15$1.00K0.00%00.0%Unchanged
BDO Wealth Advisors, LLC33$1.00K0.00%00.0%Unchanged
Key Financial Inc19$1.00K0.00%00.0%Unchanged
Orion Capital Management LLC38$1.00K0.00%00.0%Unchanged
Private Trust Co NA39$1.00K0.00%+39New
Raffa Wealth Management, LLC28$1.04K0.00%00.0%Unchanged
Kelly Financial Services LLC30$1.11K0.00%00.0%Unchanged
Earnest Partners LLC49$2.00K0.00%00.0%Unchanged
Massmutual Trust Co FSB60$2.00K0.00%+12+25.0%Added
Parkside Financial Bank & Trust62$2.00K0.00%00.0%Unchanged
Blume Capital Management, Inc.55$2.00K0.00%00.0%Unchanged
Sargent Bickham Lagudis LLC43$2.00K0.00%00.0%Unchanged
Trustcore Financial Services, LLC58$2.00K0.00%00.0%Unchanged
Lindbrook Capital, LLC57$2.00K0.00%00.0%Unchanged
CoreCap Advisors, LLC64$2.00K0.00%+64New
Rockbridge Investment Management, LCC58$2.15K0.00%00.0%Unchanged
Venture Visionary Partners LLC63$2.33K0.00%+63New
Cutler Group LP100$3.00K0.00%−2,900−96.7%Reduced
Concord Wealth Partners82$3.00K0.00%−71−46.4%Reduced
Gradient Investments LLC91$3.00K0.00%00.0%Unchanged
Centerpoint Advisors, LLC68$3.00K0.00%00.0%Unchanged
Versant Capital Management, Inc78$3.00K0.00%00.0%Unchanged
Global Wealth Management Investment Advisory, Inc.80$3.00K0.00%00.0%Unchanged
Raleigh Capital Management Inc.72$3.00K0.00%00.0%Unchanged
Bogart Wealth, LLC85$3.00K0.00%+55+183.3%Added
TD Waterhouse Canada Inc.100$3.80K0.00%00.0%Unchanged
Benjamin F. Edwards & Company, Inc.119$4.00K0.00%00.0%Unchanged
GPS Wealth Strategies Group, LLC119$4.00K0.00%00.0%Unchanged
Bell Investment Advisors, Inc102$4.00K0.00%+102New
Umb Bank N A129$5.00K0.00%−13−9.2%Reduced
Monolith Advisors133$5.00K0.01%00.0%Unchanged
Pacifica Partners Inc.150$6.00K0.00%00.0%Unchanged
Meeder Asset Management Inc186$7.00K0.00%00.0%Unchanged
Clearstead Advisors, LLC185$7.00K0.00%00.0%Unchanged
AllSquare Wealth Management LLC198$7.00K0.00%00.0%Unchanged
Insight Financial Services200$7.00K0.02%00.0%Unchanged
Carolinas Wealth Consulting LLC187$7.00K0.00%00.0%Unchanged
WFA of San Diego, LLC200$7.00K0.01%+200New
Signaturefd, LLC242$9.00K0.00%−299−55.3%Reduced
Hall Laurie J Trustee270$10.0K0.00%00.0%Unchanged
Quadrant Capital Group LLC263$10.0K0.00%−4−1.5%Reduced
Gables Capital Management Inc.275$10.0K0.01%00.0%Unchanged
Spire Wealth Management306$11.0K0.00%−63−17.1%Reduced
American Portfolios Advisors300$11.1K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC359$13.0K0.00%00.0%Unchanged
Steward Partners Investment Advisory, LLC362$13.0K0.00%00.0%Unchanged
Covestor Ltd366$14.0K0.01%−11−2.9%Reduced
Whittier Trust Co of Nevada Inc405$15.0K0.00%00.0%Unchanged
Global Trust Asset Management, LLC399$15.0K0.01%00.0%Unchanged
Banque Cantonale Vaudoise400$15.0K0.00%00.0%Unchanged
Ellis Investment Partners, LLC500$18.0K0.00%−63−11.2%Reduced
Riverview Trust Co476$18.0K0.02%00.0%Unchanged
Daiwa Securities Group Inc.528$20.0K0.00%+116+28.2%Added
Elequin Capital LP532$20.0K0.00%+172+47.8%Added
AlphaMark Advisors, LLC555$21.0K0.01%00.0%Unchanged
Laurel Wealth Advisors LLC600$22.0K0.01%00.0%Unchanged
Ronald Blue Trust, Inc.675$25.0K0.00%+675New
Heritage Wealth Management, LLC676$25.0K0.01%00.0%Unchanged
Glassman Wealth Services739$27.0K0.01%−83−10.1%Reduced
Allworth Financial LP739$27.0K0.00%00.0%Unchanged
Parallel Advisors, LLC724$27.0K0.00%+8+1.1%Added
Institutional & Family Asset Management, LLC746$28.0K0.00%00.0%Unchanged
Zullo Investment Group, Inc.817$30.0K0.02%00.0%Unchanged
Altshuler Shaham Ltd834$31.0K0.00%+834New
Archer Investment Corp850$31.5K0.01%00.0%Unchanged
Heritage Financial Services, LLC900$33.0K0.02%+900New
Riggs Asset Managment Co. Inc.997$37.0K0.02%00.0%Unchanged
United Community Bank1,046$38.7K0.04%+79+8.2%Added
Wolff Wiese Magana LLC1,074$40.0K0.03%−57−5.0%Reduced
Quantbot Technologies LP1,200$44.0K0.00%+1,200New
International Biotechnology Trust PLC1,703$46.1K0.91%−152,385−98.9%Reduced
Kistler-Tiffany Companies, LLC1,281$47.0K0.01%00.0%Unchanged
Harbour Investments, Inc.1,260$47.0K0.00%+1,260New
KBC Group NV1,378$51.0K0.00%−6,661−82.9%Reduced
Tower Research Capital LLC (TRC)1,430$53.0K0.00%−7,298−83.6%Reduced
Captrust Financial Advisors1,429$53.0K0.00%+249+21.1%Added
Washington Trust Advisors, Inc.1,637$61.0K0.01%−394−19.4%Reduced
CWM, LLC1,719$64.0K0.00%+165+10.6%Added
Leonteq Securities AG1,954$72.3K0.00%−273−12.3%Reduced
First Manhattan Co1,975$73.0K0.00%+775+64.6%Added
American International Group, Inc.2,147$79.0K0.00%−421−16.4%Reduced
Fifth Third Bancorp2,500$93.0K0.00%−214−7.9%Reduced
Itau Unibanco Holding S.A.2,651$98.0K0.00%−140−5.0%Reduced
Semmax Financial Advisors Inc.2,327$107.0K0.04%−247−9.6%Reduced
Canada Pension Plan Investment Board3,124$116.0K0.00%−6,487−67.5%Reduced
NuWave Investment Management, LLC3,434$127.0K0.17%+3,434New
Geneos Wealth Management Inc.3,435$130.0K0.01%−1,628−32.2%Reduced
Caldwell Trust Co4,000$148.1K0.02%00.0%Unchanged
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.4,394$163.0K0.00%−2,972−40.3%Reduced