Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q2 2022
Institutional positions in Ionis Pharmaceuticals Inc as of Jun 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 351
- +22 vs. Q1 2022
- Shares held
- 124.6M
- +27.5K (0.0%) vs. Q1 2022
- Total value
- $4.61B
- −$315.6K (0.0%) vs. Q1 2022
- New holders
- 53
- 89 more added
- Sold out
- 31
- 130 more reduced
4 institutions that held it in Q1 2022 haven't filed for Q2 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q2 2022
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q1 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Davenport & Co LLC | 83,318 | $3.08M | 0.03% | −545−0.6% | Reduced |
| LPL Financial LLC | 82,087 | $3.04M | 0.00% | −12,466−13.2% | Reduced |
| State of New Jersey Common Pension Fund D | 80,433 | $2.98M | 0.01% | −8,446−9.5% | Reduced |
| Public Employees Retirement System of Ohio | 75,343 | $2.79M | 0.01% | −2,323−3.0% | Reduced |
| Tudor Investment Corp Et Al | 74,192 | $2.75M | 0.08% | +44,667+151.3% | Added |
| PFS Investments Inc. | 74,125 | $2.74M | 0.06% | −936−1.2% | Reduced |
| SG Americas Securities, LLC | 72,557 | $2.69M | 0.04% | +60,966+526.0% | Added |
| Eaton Vance Management | 69,598 | $2.58M | 0.00% | +13,033+23.0% | Added |
| Ergoteles LLC | 69,124 | $2.56M | 0.08% | +31,124+81.9% | Added |
| Guggenheim Capital LLC | 63,746 | $2.36M | 0.02% | −4,491−6.6% | Reduced |
| Occudo Quantitative Strategies LP | 61,671 | $2.28M | 0.19% | +61,671 | New |
| UBS Oconnor LLC | 61,497 | $2.28M | 0.02% | +61,497 | New |
| Gotham Asset Management, LLC | 61,484 | $2.28M | 0.07% | +23,057+60.0% | Added |
| Graham Capital Management, L.P. | 61,013 | $2.26M | 0.10% | +40,913+203.5% | Added |
| Alliancebernstein L.P. | 60,860 | $2.25M | 0.00% | −1,079−1.7% | Reduced |
| PDT Partners, LLC | 59,865 | $2.22M | 0.20% | −20,205−25.2% | Reduced |
| Treasurer of the State of North Carolina | 59,742 | $2.21M | 0.01% | +8,071+15.6% | Added |
| Voya Investment Management LLC | 56,555 | $2.09M | 0.01% | −7,710−12.0% | Reduced |
| Employees Retirement System of Texas | 54,409 | $2.01M | 0.03% | +22,000+67.9% | Added |
| Raymond James Financial Services Advisors, Inc. | 54,230 | $2.01M | 0.00% | +3,645+7.2% | Added |
| Erste Asset Management GmbH | 51,300 | $1.93M | 0.04% | 00.0% | Unchanged |
| Rhenman & Partners Asset Management AB | 50,000 | $1.85M | 0.21% | −21,000−29.6% | Reduced |
| HSBC Holdings PLC | 47,206 | $1.78M | 0.00% | +40,609+615.6% | Added |
| Winton Group Ltd | 42,634 | $1.58M | 0.08% | +42,634 | New |
| NJ State Employees Deferred Compensation Plan | 42,000 | $1.55M | 0.25% | 00.0% | Unchanged |
| Arrowstreet Capital, Limited Partnership | 41,104 | $1.52M | 0.00% | +41,104 | New |
| Capital Counsel LLC | 41,010 | $1.52M | 0.09% | 00.0% | Unchanged |
| Envestnet Asset Management Inc | 40,365 | $1.49M | 0.00% | −50,506−55.6% | Reduced |
| Highland Capital Management, LLC | 39,159 | $1.45M | 0.10% | +39,159 | New |
| Capital Fund Management S.A. | 39,110 | $1.45M | 0.04% | −5,609−12.5% | Reduced |
| Koss-Olinger Consulting, LLC | 38,922 | $1.44M | 0.26% | −5,198−11.8% | Reduced |
| ExodusPoint Capital Management, LP | 37,590 | $1.39M | 0.02% | +37,590 | New |
| Susquehanna International Group, LLP | 37,553 | $1.39M | 0.00% | −12,173−24.5% | Reduced |
| AlphaCrest Capital Management LLC | 36,447 | $1.35M | 0.07% | −21,845−37.5% | Reduced |
| Knowledge Leaders Capital, LLC | 34,640 | $1.28M | 1.24% | +34,640 | New |
| Simplex Trading, LLC | 34,626 | $1.28M | 0.04% | +30,547+748.9% | Added |
| Arizona State Retirement System | 34,441 | $1.27M | 0.01% | +87+0.3% | Added |
| Amalgamated Bank | 33,323 | $1.23M | 0.01% | +1,389+4.3% | Added |
| Macquarie Group Ltd | 33,268 | $1.23M | 0.00% | +1,262+3.9% | Added |
| Deutsche Bank AG | 32,465 | $1.20M | 0.00% | −897−2.7% | Reduced |
| Prospera Financial Services Inc | 31,284 | $1.16M | 0.06% | +26,644+574.2% | Added |
| Janney Montgomery Scott LLC | 30,658 | $1.14M | 0.01% | −7,956−20.6% | Reduced |
| MML Investors Services, LLC | 29,479 | $1.09M | 0.01% | +1,357+4.8% | Added |
| Trexquant Investment LP | 28,423 | $1.05M | 0.05% | −19,339−40.5% | Reduced |
| Grandfield & Dodd, LLC | 28,276 | $1.05M | 0.08% | +275+1.0% | Added |
| Federated Hermes, Inc. | 27,237 | $1.01M | 0.00% | +8,875+48.3% | Added |
| Cordatus Wealth Management LLC | 26,083 | $966.0K | 0.45% | +26,083 | New |
| Brookstone Capital Management | 25,341 | $941.0K | 0.02% | +2,970+13.3% | Added |
| Algert Global LLC | 24,900 | $922.0K | 0.07% | +11,556+86.6% | Added |
| Ensign Peak Advisors, Inc | 24,870 | $921.0K | 0.00% | 00.0% | Unchanged |
| Commonwealth Equity Services, LLC | 23,764 | $879.0K | 0.00% | −2,229−8.6% | Reduced |
| Vestmark Advisory Solutions, Inc. | 23,595 | $874.0K | 0.05% | +4,434+23.1% | Added |
| Janus Henderson Group PLC | 23,207 | $858.0K | 0.00% | −2,516−9.8% | Reduced |
| Kestra Advisory Services, LLC | 22,831 | $845.0K | 0.01% | −786−3.3% | Reduced |
| Virtu Financial LLC | 22,794 | $844.0K | 0.07% | +22,794 | New |
| Allianz Asset Management GmbH | 22,497 | $833.0K | 0.00% | −59,333−72.5% | Reduced |
| Storebrand Asset Management AS | 22,462 | $831.5K | 0.00% | 00.0% | Unchanged |
| Truist Financial Corp | 22,364 | $828.0K | 0.00% | −8,906−28.5% | Reduced |
| Skandinaviska Enskilda Banken AB (publ) | 20,878 | $773.0K | 0.01% | 00.0% | Unchanged |
| Ziegler Capital Management, LLC | 20,779 | $769.0K | 0.03% | +20,779 | New |
| Global Retirement Partners, LLC | 20,431 | $756.0K | 0.06% | +90+0.4% | Added |
| Teacher Retirement System of Texas | 20,265 | $750.0K | 0.01% | −5,947−22.7% | Reduced |
| Public Employees Retirement Association of Colorado | 19,604 | $726.0K | 0.00% | 00.0% | Unchanged |
| Handelsbanken Fonder AB | 18,511 | $685.0K | 0.00% | +4,800+35.0% | Added |
| Dynamic Technology Lab Private Ltd | 18,310 | $678.0K | 0.08% | +18,310 | New |
| AtonRa Partners | 18,146 | $672.0K | 0.62% | +18,146 | New |
| Advisor Group Holdings, Inc. | 17,424 | $646.0K | 0.00% | −2,142−10.9% | Reduced |
| US Bancorp | 17,323 | $641.0K | 0.00% | −4,135−19.3% | Reduced |
| Cetera Advisor Networks LLC | 17,276 | $640.0K | 0.01% | +1,295+8.1% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 16,734 | $619.0K | 0.00% | −1,514−8.3% | Reduced |
| Engineers Gate Manager LP | 16,703 | $618.0K | 0.02% | +6,835+69.3% | Added |
| Profund Advisors LLC | 16,203 | $600.0K | 0.04% | −1,389−7.9% | Reduced |
| Fox Run Management, L.L.C. | 15,947 | $590.0K | 0.29% | +6,893+76.1% | Added |
| Natixis Advisors, L.P. | 15,830 | $586.0K | 0.00% | −31−0.2% | Reduced |
| Castle Rock Wealth Management, LLC | 15,593 | $573.0K | 0.29% | 00.0% | Unchanged |
| Xponance, Inc. | 15,418 | $571.0K | 0.01% | +520+3.5% | Added |
| Blair William & Co | 14,607 | $541.0K | 0.00% | −121−0.8% | Reduced |
| Oppenheimer & Co Inc | 14,560 | $539.0K | 0.01% | −2,000−12.1% | Reduced |
| Vontobel Holding Ltd. | 14,210 | $534.0K | 0.01% | −505−3.4% | Reduced |
| Shell Asset Management Co | 14,216 | $526.0K | 0.02% | +3,194+29.0% | Added |
| North Star Asset Management Inc | 13,680 | $506.0K | 0.03% | 00.0% | Unchanged |
| Victory Capital Management Inc | 13,546 | $501.0K | 0.00% | +1,721+14.6% | Added |
| ProShare Advisors LLC | 13,367 | $495.0K | 0.00% | −4,534−25.3% | Reduced |
| Lincoln National Corp | 13,261 | $491.0K | 0.01% | 00.0% | Unchanged |
| Point72 Asset Management, L.P. | 13,185 | $488.0K | 0.00% | +13,185 | New |
| Creative Planning | 12,729 | $471.0K | 0.00% | −29−0.2% | Reduced |
| E Fund Management Co., Ltd. | 12,597 | $466.0K | 0.04% | +4,263+51.2% | Added |
| Comerica Bank | 11,684 | $459.0K | 0.00% | −71−0.6% | Reduced |
| Teza Capital Management LLC | 12,225 | $453.0K | 0.17% | +4,707+62.6% | Added |
| Arden Trust Co | 12,192 | $451.0K | 0.10% | −126−1.0% | Reduced |
| Strategic Wealth Advisors Group, LLC | 12,090 | $445.0K | 0.02% | −9,394−43.7% | Reduced |
| Man Group plc | – | $442.0K | 0.00% | – | New |
| Stephens Inc | 11,644 | $431.0K | 0.01% | −908−7.2% | Reduced |
| Ameriprise Financial Inc | 11,384 | $421.0K | 0.00% | −1,298−10.2% | Reduced |
| Campbell & CO Investment Adviser LLC | 11,299 | $418.0K | 0.11% | +11,299 | New |
| Plancorp, LLC | 11,235 | $416.0K | 0.03% | +23+0.2% | Added |
| Hanseatic Management Services Inc | 11,222 | $415.0K | 0.94% | +11,222 | New |
| Cambridge Investment Research Advisors, Inc. | 11,122 | $412.0K | 0.00% | +655+6.3% | Added |
| Neuberger Berman Group LLC | 11,086 | $410.0K | 0.00% | +11,086 | New |
| Oppenheimer Asset Management Inc. | 10,903 | $403.0K | 0.01% | −92−0.8% | Reduced |