Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q1 2022
Institutional positions in Ionis Pharmaceuticals Inc as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 333
- −3 vs. Q4 2021
- Shares held
- 125.0M
- +1.76M (+1.4%) vs. Q4 2021
- Total value
- $4.63B
- +$876.1M (+23.4%) vs. Q4 2021
- New holders
- 47
- 107 more added
- Sold out
- 50
- 109 more reduced
5 institutions that held it in Q4 2021 haven't filed for Q1 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q1 2022
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q4 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| FDx Advisors, Inc. | 5,575 | $206.0K | 0.01% | +5,575 | New |
| American Century Companies Inc | 5,594 | $207.0K | 0.00% | +5,594 | New |
| CIBC Asset Management Inc | 5,583 | $207.0K | 0.00% | +5,583 | New |
| Toroso Investments, LLC | 5,577 | $207.0K | 0.01% | +5,577 | New |
| JustInvest LLC | 5,596 | $207.0K | 0.01% | +5,596 | New |
| FORA Capital, LLC | 6,095 | $218.0K | 0.04% | +6,095 | New |
| First Republic Investment Management, Inc. | 6,106 | $226.0K | 0.00% | +6,106 | New |
| Delphia (USA) Inc. | 6,216 | $230.0K | 0.17% | +6,216 | New |
| Stonegate Investment Group, LLC | 6,374 | $236.0K | 0.01% | +6,374 | New |
| HSBC Holdings PLC | 6,597 | $242.0K | 0.00% | +6,597 | New |
| Aristides Capital LLC | 6,891 | $255.0K | 0.17% | +6,891 | New |
| Great West Life Assurance Co | 6,605 | $260.0K | 0.00% | −438−6.2% | Reduced |
| Foundations Investment Advisors, LLC | 6,355 | $260.0K | 0.01% | +6,355 | New |
| Beacon Pointe Advisors, LLC | 7,055 | $261.0K | 0.00% | +7,055 | New |
| Bridgewater Associates, LP | 7,201 | $267.0K | 0.00% | +7,201 | New |
| Echo Street Capital Management LLC | 7,223 | $268.0K | 0.00% | +7,223 | New |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 7,366 | $273.0K | 0.00% | +492+7.2% | Added |
| Utah Retirement Systems | 7,400 | $274.0K | 0.00% | −18,009−70.9% | Reduced |
| Martingale Asset Management L P | 7,405 | $275.0K | 0.00% | +7,405 | New |
| Teza Capital Management LLC | 7,518 | $278.0K | 0.10% | −4,327−36.5% | Reduced |
| Northeast Financial Consultants Inc | 7,740 | $287.0K | 0.02% | 00.0% | Unchanged |
| IHT Wealth Management, LLC | 7,878 | $292.0K | 0.02% | −50−0.6% | Reduced |
| Horizon Kinetics Asset Management LLC | 8,000 | $296.0K | 0.01% | 00.0% | Unchanged |
| Commerce Bank | 7,998 | $296.0K | 0.00% | +7,998 | New |
| KBC Group NV | 8,039 | $298.0K | 0.00% | +22+0.3% | Added |
| Boston Partners | 8,037 | $298.0K | 0.00% | +247+3.2% | Added |
| Nicollet Investment Management, Inc. | 8,269 | $306.0K | 0.14% | −235−2.8% | Reduced |
| E Fund Management Co., Ltd. | 8,334 | $309.0K | 0.01% | +8,334 | New |
| Brandywine Managers, LLC | 8,460 | $313.0K | 0.54% | 00.0% | Unchanged |
| Independent Financial Group, LLC | 8,490 | $314.5K | 0.03% | +8,490 | New |
| Tanaka Capital Management Inc | 8,547 | $317.0K | 0.64% | −315−3.6% | Reduced |
| MetLife Investment Management | 8,579 | $317.8K | 0.00% | +8,579 | New |
| Tower Research Capital LLC (TRC) | 8,728 | $323.0K | 0.00% | +7,502+611.9% | Added |
| Corton Capital Inc. | 8,809 | $326.0K | 0.14% | +8,809 | New |
| Fox Run Management, L.L.C. | 9,054 | $335.0K | 0.19% | +1,730+23.6% | Added |
| HighTower Advisors, LLC | 9,112 | $336.0K | 0.00% | −18,026−66.4% | Reduced |
| National Asset Management, Inc. | 9,098 | $337.0K | 0.01% | +2,377+35.4% | Added |
| Regions Financial Corp | 9,323 | $345.0K | 0.00% | 00.0% | Unchanged |
| Canada Pension Plan Investment Board | 9,611 | $356.0K | 0.00% | −48,313−83.4% | Reduced |
| The PNC Financial Services Group, Inc. | 9,662 | $358.0K | 0.00% | +831+9.4% | Added |
| Wrapmanager Inc | 9,714 | $360.0K | 0.10% | +1,396+16.8% | Added |
| Berkshire Asset Management LLC | 9,739 | $361.0K | 0.02% | +500+5.4% | Added |
| Kennedy Capital Management, Inc. | 9,848 | $365.0K | 0.01% | +2,315+30.7% | Added |
| Engineers Gate Manager LP | 9,868 | $366.0K | 0.01% | −24,512−71.3% | Reduced |
| Maryland State Retirement & Pension System | 9,956 | $369.0K | 0.01% | 00.0% | Unchanged |
| Brown Advisory Securities, LLC | 10,000 | $370.0K | 0.22% | −3,000−23.1% | Reduced |
| Pearl River Capital, LLC | 10,153 | $376.0K | 0.10% | +10,153 | New |
| Baird Financial Group, Inc. | 10,293 | $381.0K | 0.00% | −1,063−9.4% | Reduced |
| Cambridge Investment Research Advisors, Inc. | 10,467 | $388.0K | 0.00% | +20+0.2% | Added |
| Y-Intercept (Hong Kong) Ltd | 10,689 | $396.0K | 0.09% | +10,689 | New |
| SEI Investments Co | 11,018 | $407.0K | 0.00% | −176−1.6% | Reduced |
| Oppenheimer Asset Management Inc. | 10,995 | $407.0K | 0.01% | +1,213+12.4% | Added |
| Shell Asset Management Co | 11,022 | $408.0K | 0.01% | −1,629−12.9% | Reduced |
| Plancorp, LLC | 11,212 | $415.0K | 0.03% | −62−0.5% | Reduced |
| Rockefeller Capital Management L.P. | 11,256 | $416.0K | 0.00% | −836−6.9% | Reduced |
| SG Americas Securities, LLC | 11,591 | $429.0K | 0.00% | −1,341−10.4% | Reduced |
| Victory Capital Management Inc | 11,825 | $435.0K | 0.00% | −1,322−10.1% | Reduced |
| IFP Advisors, Inc | 9,162 | $445.0K | 0.01% | +6,489+242.8% | Added |
| Virtus ETF Advisers LLC | 12,296 | $455.0K | 0.20% | 00.0% | Unchanged |
| Arden Trust Co | 12,318 | $456.0K | 0.09% | −3,236−20.8% | Reduced |
| Stephens Inc | 12,552 | $465.0K | 0.01% | −5,149−29.1% | Reduced |
| Ameriprise Financial Inc | 12,682 | $467.0K | 0.00% | +3,055+31.7% | Added |
| Creative Planning | 12,758 | $472.0K | 0.00% | −2,358−15.6% | Reduced |
| Lincoln National Corp | 13,261 | $491.0K | 0.01% | −809−5.7% | Reduced |
| Cowen and Company, LLC | 13,257 | $491.0K | 0.05% | +5,527+71.5% | Added |
| Algert Global LLC | 13,344 | $494.0K | 0.03% | −25,086−65.3% | Reduced |
| Comerica Bank | 11,755 | $506.0K | 0.00% | 00.0% | Unchanged |
| North Star Asset Management Inc | 13,680 | $507.0K | 0.03% | 00.0% | Unchanged |
| Handelsbanken Fonder AB | 13,711 | $508.0K | 0.00% | −10,700−43.8% | Reduced |
| Vontobel Holding Ltd. | 14,715 | $545.0K | 0.00% | +3,405+30.1% | Added |
| Blair William & Co | 14,728 | $546.0K | 0.00% | +264+1.8% | Added |
| SG3 Management, LLC | 14,780 | $547.0K | 0.15% | +6,280+73.9% | Added |
| Xponance, Inc. | 14,898 | $552.0K | 0.01% | +8+0.1% | Added |
| Seven Eight Capital, LP | 15,796 | $585.0K | 0.08% | +15,796 | New |
| Natixis Advisors, L.P. | 15,861 | $587.0K | 0.00% | −34−0.2% | Reduced |
| Cetera Advisor Networks LLC | 15,981 | $592.0K | 0.01% | +3,156+24.6% | Added |
| Oppenheimer & Co Inc | 16,560 | $613.0K | 0.01% | −1,798−9.8% | Reduced |
| Bradley Foster & Sargent Inc | 17,050 | $632.0K | 0.01% | +17,050 | New |
| Castle Rock Wealth Management, LLC | 15,593 | $639.0K | 0.29% | 00.0% | Unchanged |
| Profund Advisors LLC | 17,592 | $652.0K | 0.03% | −1,825−9.4% | Reduced |
| ProShare Advisors LLC | 17,901 | $663.0K | 0.00% | −5,531−23.6% | Reduced |
| Weiss Asset Management LP | 18,145 | $672.0K | 0.02% | +18,145 | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 18,248 | $676.0K | 0.00% | −3,873−17.5% | Reduced |
| Federated Hermes, Inc. | 18,362 | $680.0K | 0.00% | +14,109+331.7% | Added |
| Squarepoint Ops LLC | 18,894 | $700.0K | 0.01% | −42,446−69.2% | Reduced |
| Vestmark Advisory Solutions, Inc. | 19,161 | $710.0K | 0.04% | +583+3.1% | Added |
| Public Employees Retirement Association of Colorado | 19,604 | $726.0K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 19,566 | $728.0K | 0.00% | +419+2.2% | Added |
| Graham Capital Management, L.P. | 20,100 | $744.0K | 0.03% | +13,296+195.4% | Added |
| Global Retirement Partners, LLC | 20,341 | $755.0K | 0.06% | +20,341 | New |
| Skandinaviska Enskilda Banken AB (publ) | 20,878 | $773.0K | 0.00% | 00.0% | Unchanged |
| US Bancorp | 21,458 | $795.0K | 0.00% | +2,343+12.3% | Added |
| Strategic Wealth Advisors Group, LLC | 21,484 | $813.0K | 0.03% | +21,484 | New |
| Storebrand Asset Management AS | 22,462 | $832.0K | 0.00% | 00.0% | Unchanged |
| Kestra Advisory Services, LLC | 23,617 | $875.0K | 0.01% | +3,936+20.0% | Added |
| Brookstone Capital Management | 22,371 | $886.0K | 0.02% | +8,424+60.4% | Added |
| Ensign Peak Advisors, Inc | 24,870 | $921.0K | 0.00% | −3,460−12.2% | Reduced |
| Janus Henderson Group PLC | 25,723 | $953.0K | 0.00% | +70.0% | Added |
| Commonwealth Equity Services, LLC | 25,993 | $962.0K | 0.00% | −2,773−9.6% | Reduced |
| Teacher Retirement System of Texas | 26,212 | $971.0K | 0.00% | +1,758+7.2% | Added |