Ionis Pharmaceuticals Inc
IONS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000874015
In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.
13F holders, Q4 2021
Institutional positions in Ionis Pharmaceuticals Inc as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 341
- +20 vs. Q3 2021
- Shares held
- 123.2M
- +1.71M (+1.4%) vs. Q3 2021
- Total value
- $3.75B
- −$326.3M (−8.0%) vs. Q3 2021
- New holders
- 59
- 106 more added
- Sold out
- 39
- 119 more reduced
5 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IONS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 515 | $14.3B |
| Q1 2026 | 497 | $13.0B |
| Q4 2025 | 494 | $13.5B |
| Q3 2025 | 437 | $11.0B |
| Q2 2025 | 363 | $6.67B |
| Q1 2025 | 344 | $5.03B |
| Q4 2024 | 356 | $5.61B |
| Q3 2024 | 354 | $6.31B |
| Q2 2024 | 357 | $6.83B |
| Q1 2024 | 361 | $6.17B |
| Q4 2023 | 365 | $7.21B |
| Q3 2023 | 312 | $6.35B |
| Q2 2023 | 305 | $5.60B |
| Q1 2023 | 315 | $4.69B |
| Q4 2022 | 339 | $4.93B |
| Q3 2022 | 350 | $5.59B |
| Q2 2022 | 351 | $4.61B |
| Q1 2022 | 333 | $4.63B |
| Q4 2021 | 341 | $3.75B |
| Q3 2021 | 326 | $4.08B |
| Q2 2021 | 338 | $4.96B |
| Q1 2021 | 365 | $5.55B |
Institutions, Q4 2021
Shares, value and share of portfolio for each institution holding Ionis Pharmaceuticals Inc; share changes are against Q3 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Brookfield Asset Management Inc. | 9,638 | $293.0K | 0.00% | +9,638 | New |
| Regions Financial Corp | 9,323 | $284.0K | 0.00% | −100−1.1% | Reduced |
| Berkshire Asset Management LLC | 9,239 | $281.0K | 0.02% | −3,821−29.3% | Reduced |
| Tanaka Capital Management Inc | 8,862 | $270.0K | 0.51% | −7,799−46.8% | Reduced |
| The PNC Financial Services Group, Inc. | 8,831 | $269.0K | 0.00% | +32+0.4% | Added |
| Metropolitan Life Insurance Co | 8,813 | $268.2K | 0.00% | −67−0.8% | Reduced |
| SG3 Management, LLC | 8,500 | $259.0K | 0.03% | −10,000−54.1% | Reduced |
| Nicollet Investment Management, Inc. | 8,504 | $259.0K | 0.10% | −1,997−19.0% | Reduced |
| Brandywine Managers, LLC | 8,460 | $257.0K | 0.29% | 00.0% | Unchanged |
| Wrapmanager Inc | 8,318 | $253.0K | 0.06% | −2,006−19.4% | Reduced |
| KBC Group NV | 8,017 | $244.0K | 0.00% | −895−10.0% | Reduced |
| Horizon Kinetics Asset Management LLC | 8,000 | $243.0K | 0.01% | 00.0% | Unchanged |
| Ergoteles LLC | 7,955 | $242.0K | 0.01% | −44,917−85.0% | Reduced |
| IHT Wealth Management, LLC | 7,928 | $241.0K | 0.02% | +7,928 | New |
| Boston Partners | 7,790 | $237.0K | 0.00% | +7,790 | New |
| Northeast Financial Consultants Inc | 7,740 | $236.0K | 0.01% | 00.0% | Unchanged |
| Cowen and Company, LLC | 7,730 | $235.0K | 0.02% | −5,113−39.8% | Reduced |
| Kennedy Capital Management, Inc. | 7,533 | $229.0K | 0.00% | −531−6.6% | Reduced |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 6,874 | $224.0K | 0.00% | +630+10.1% | Added |
| Fox Run Management, L.L.C. | 7,324 | $223.0K | 0.13% | −17−0.2% | Reduced |
| Virginia Retirement Systems Et Al | 7,200 | $219.0K | 0.00% | −4,500−38.5% | Reduced |
| Great West Life Assurance Co | 7,043 | $214.0K | 0.00% | +121+1.7% | Added |
| Graham Capital Management, L.P. | 6,804 | $207.0K | 0.01% | +6,804 | New |
| National Asset Management, Inc. | 6,721 | $205.0K | 0.01% | −4,297−39.0% | Reduced |
| Leonteq Securities AG | 6,236 | $189.8K | 0.01% | +757+13.8% | Added |
| Lazard Asset Management LLC | 5,814 | $176.0K | 0.00% | +4,554+361.4% | Added |
| Geneos Wealth Management Inc. | 5,066 | $154.0K | 0.01% | +228+4.7% | Added |
| Quantbot Technologies LP | 5,076 | $154.0K | 0.01% | +5,076 | New |
| Beaird Harris Wealth Management, LLC | 5,000 | $152.0K | 0.06% | +5,000 | New |
| Cutler Group LP | 4,290 | $130.0K | 0.01% | +3,490+436.3% | Added |
| Federated Hermes, Inc. | 4,253 | $129.0K | 0.00% | 00.0% | Unchanged |
| Caldwell Trust Co | 4,000 | $121.7K | 0.01% | 00.0% | Unchanged |
| NuWave Investment Management, LLC | 3,762 | $114.0K | 0.13% | +3,762 | New |
| IFP Advisors, Inc | 2,673 | $93.0K | 0.00% | +953+55.4% | Added |
| NEXT Financial Group, Inc | 2,893 | $88.0K | 0.01% | +1,628+128.7% | Added |
| Itau Unibanco Holding S.A. | 2,804 | $86.0K | 0.00% | +1,563+125.9% | Added |
| Semmax Financial Advisors Inc. | 2,775 | $84.0K | 0.03% | −656−19.1% | Reduced |
| Fifth Third Bancorp | 2,626 | $80.0K | 0.00% | 00.0% | Unchanged |
| American International Group, Inc. | 2,571 | $78.0K | 0.00% | −89−3.3% | Reduced |
| Spire Wealth Management | 2,490 | $76.0K | 0.00% | +2,195+744.1% | Added |
| Washington Trust Advisors, Inc. | 2,430 | $74.0K | 0.01% | +2,430 | New |
| Koshinski Asset Management, Inc. | 2,044 | $62.2K | 0.01% | −24−1.2% | Reduced |
| Northwestern Mutual Wealth Management Co | 1,956 | $60.0K | 0.00% | −56−2.8% | Reduced |
| Twin Lakes Capital Management, LLC | 1,500 | $46.0K | 0.02% | 00.0% | Unchanged |
| Captrust Financial Advisors | 1,301 | $40.0K | 0.00% | −1,171−47.4% | Reduced |
| Kistler-Tiffany Companies, LLC | 1,281 | $39.0K | 0.01% | 00.0% | Unchanged |
| Harbour Investments, Inc. | 1,260 | $38.0K | 0.00% | −758−37.6% | Reduced |
| Tower Research Capital LLC (TRC) | 1,226 | $37.0K | 0.00% | +431+54.2% | Added |
| First Manhattan Co | 1,200 | $36.0K | 0.00% | 00.0% | Unchanged |
| Point72 Hong Kong Ltd | 1,188 | $36.0K | 0.00% | +1,188 | New |
| Wolff Wiese Magana LLC | 1,131 | $35.0K | 0.02% | 00.0% | Unchanged |
| Riggs Asset Managment Co. Inc. | 997 | $30.0K | 0.01% | 00.0% | Unchanged |
| CWM, LLC | 999 | $30.0K | 0.00% | +999 | New |
| United Community Bank | 962 | $29.3K | 0.03% | +962 | New |
| Bessemer Group Inc | 900 | $27.0K | 0.00% | 00.0% | Unchanged |
| Zullo Investment Group, Inc. | 886 | $27.0K | 0.01% | +886 | New |
| Archer Investment Corp | 850 | $25.9K | 0.01% | −67−7.3% | Reduced |
| Carroll Financial Associates, Inc. | 793 | $24.0K | 0.00% | −111−12.3% | Reduced |
| Institutional & Family Asset Management, LLC | 765 | $23.0K | 0.00% | 00.0% | Unchanged |
| Allworth Financial LP | 731 | $22.0K | 0.00% | +714+4,200.0% | Added |
| Steward Partners Investment Advisory, LLC | 705 | $21.0K | 0.00% | −2,651−79.0% | Reduced |
| Signaturefd, LLC | 676 | $21.0K | 0.00% | −210−23.7% | Reduced |
| Parallel Advisors, LLC | 621 | $19.0K | 0.00% | −102−14.1% | Reduced |
| Macroview Investment Management LLC | 616 | $19.0K | 0.02% | +616 | New |
| Laurel Wealth Advisors LLC | 600 | $18.0K | 0.00% | 00.0% | Unchanged |
| Ellis Investment Partners, LLC | 563 | $17.0K | 0.00% | +63+12.6% | Added |
| Orion Capital Management LLC | 538 | $16.0K | 0.01% | +500+1,315.8% | Added |
| Patriot Financial Group Insurance Agency, LLC | 494 | $15.0K | 0.00% | −364−42.4% | Reduced |
| Concord Wealth Partners | 453 | $14.0K | 0.00% | +336+287.2% | Added |
| FSB Premier Wealth Management, Inc. | 482 | $14.0K | 0.01% | +482 | New |
| Daiwa Securities Group Inc. | 412 | $13.0K | 0.00% | −71−14.7% | Reduced |
| Glassman Wealth Services | 423 | $13.0K | 0.00% | −16−3.6% | Reduced |
| Global Trust Asset Management, LLC | 399 | $12.0K | 0.00% | 00.0% | Unchanged |
| Banque Cantonale Vaudoise | 400 | $12.0K | 0.00% | 00.0% | Unchanged |
| Whittier Trust Co of Nevada Inc | 405 | $12.0K | 0.00% | +246+154.7% | Added |
| Nisa Investment Advisors, LLC | 359 | $11.0K | 0.00% | −5,890−94.3% | Reduced |
| Confluence Wealth Services, Inc. | 384 | $11.0K | 0.00% | +384 | New |
| Quadrant Capital Group LLC | 340 | $10.0K | 0.00% | −126−27.0% | Reduced |
| Heritage Wealth Advisors | 334 | $10.0K | 0.00% | 00.0% | Unchanged |
| American Portfolios Advisors | 300 | $9.13K | 0.00% | 00.0% | Unchanged |
| Jones Financial Companies LLLP | 300 | $9.00K | 0.00% | 00.0% | Unchanged |
| Amplius Wealth Advisors, LLC | 300 | $9.00K | 0.00% | +300 | New |
| Hall Laurie J Trustee | 270 | $8.00K | 0.00% | 00.0% | Unchanged |
| Gables Capital Management Inc. | 275 | $8.00K | 0.00% | 00.0% | Unchanged |
| Gradient Investments LLC | 277 | $8.00K | 0.00% | +186+204.4% | Added |
| Reilly Financial Advisors, LLC | 220 | $7.00K | 0.00% | 00.0% | Unchanged |
| Carolinas Wealth Consulting LLC | 187 | $6.00K | 0.00% | −3,000−94.1% | Reduced |
| AllSquare Wealth Management LLC | 198 | $6.00K | 0.00% | 00.0% | Unchanged |
| Proequities, Inc. | 203 | $6.00K | 0.00% | +83+69.2% | Added |
| Clearstead Advisors, LLC | 185 | $6.00K | 0.00% | +185 | New |
| Insight Financial Services | 200 | $6.00K | 0.00% | +200 | New |
| Pinnacle Bancorp, Inc. | 179 | $5.00K | 0.00% | −48−21.1% | Reduced |
| AlphaMark Advisors, LLC | 180 | $5.00K | 0.00% | −15−7.7% | Reduced |
| Logan Capital Management Inc | 178 | $5.00K | 0.00% | 00.0% | Unchanged |
| Pacifica Partners Inc. | 150 | $5.00K | 0.00% | 00.0% | Unchanged |
| GPS Wealth Strategies Group, LLC | 119 | $4.00K | 0.00% | 00.0% | Unchanged |
| Benjamin F. Edwards & Company, Inc. | 119 | $4.00K | 0.00% | +55+85.9% | Added |
| Umb Bank N A | 142 | $4.00K | 0.00% | +142 | New |
| Monolith Advisors | 133 | $4.00K | 0.00% | +133 | New |
| TD Waterhouse Canada Inc. | 100 | $3.13K | 0.00% | +100 | New |