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Ionis Pharmaceuticals Inc

IONS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000874015

In the last 90 days, Ionis Pharmaceuticals Inc insiders filed 1 open-market purchase and 4 sales; 515 institutions reported holding it in 13F filings for Q2 2026, worth $14.3B in total; ARK Invest is the only superinvestor holding it.

Q4 2021 vs. Q3 2021

How the institutions holding Ionis Pharmaceuticals Inc changed between Q3 2021 and Q4 2021.

All holders in Q4 2021All holders in Q3 2021

13F holders of IONS: Q3 2021 compared with Q4 2021
MeasureQ3 2021Of which not filed for Q4 2021Q4 2021Change
Holders3265341+20
Shares121.7M198.9K123.2M+1.71M (+1.4%)
Value$4.08B$6.67M$3.75B−$326.3M (−8.0%)

5 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so the changes leave them out.

New holders (59)

Institutions that held Ionis Pharmaceuticals Inc at the end of Q4 2021 but not at the end of Q3 2021.

Institutions new to IONS in Q4 2021
InstitutionSharesValue% of portfolio
Privium Fund Management B.V.630,199$19.2M3.83%
Sio Capital Management, LLC322,566$9.82M2.99%
Natixis300,797$9.15M0.03%
Voloridge Investment Management, LLC266,845$8.12M0.04%
MUFG Securities EMEA plc200,000$6.09M0.13%
Alps Advisors Inc163,424$4.97M0.06%
Sonora Investment Management Group, LLC156,790$4.77M0.55%
Jump Financial, LLC120,500$3.67M0.23%
Allspring Global Investments Holdings, LLC98,574$3.00M0.00%
National Bank of Canada70,000$2.13M0.01%
PDT Partners, LLC67,697$2.06M0.16%
Canada Pension Plan Investment Board57,924$1.76M0.00%
Alpha DNA Investment Management LLC50,614$1.54M0.98%
Pura Vida Investments, LLC48,544$1.48M0.15%
Healthcare of Ontario Pension Plan Trust Fund34,069$1.04M0.00%
Ensign Peak Advisors, Inc28,330$862.0K0.00%
Capital Fund Management S.A.28,108$855.3K0.02%
Occudo Quantitative Strategies LP26,650$811.0K0.07%
AE Wealth Management LLC26,085$794.0K0.01%
Quantamental Technologies LLC17,671$538.0K0.27%
Verition Fund Management LLC13,740$418.0K0.01%
Gsa Capital Partners LLP13,368$407.0K0.05%
Wellington Management Group LLP13,134$399.0K0.00%
Teza Capital Management LLC11,845$360.0K0.10%
Vontobel Holding Ltd.11,310$344.0K0.00%
Greenup Street Wealth Management LLC11,145$339.0K0.20%
Brookfield Asset Management Inc.9,638$293.0K0.00%
IHT Wealth Management, LLC7,928$241.0K0.02%
Boston Partners7,790$237.0K0.00%
Graham Capital Management, L.P.6,804$207.0K0.01%
Quantbot Technologies LP5,076$154.0K0.01%
Beaird Harris Wealth Management, LLC5,000$152.0K0.06%
NuWave Investment Management, LLC3,762$114.0K0.13%
Washington Trust Advisors, Inc.2,430$74.0K0.01%
Point72 Hong Kong Ltd1,188$36.0K0.00%
CWM, LLC999$30.0K0.00%
United Community Bank962$29.3K0.03%
Zullo Investment Group, Inc.886$27.0K0.01%
Macroview Investment Management LLC616$19.0K0.02%
FSB Premier Wealth Management, Inc.482$14.0K0.01%
Confluence Wealth Services, Inc.384$11.0K0.00%
Amplius Wealth Advisors, LLC300$9.00K0.00%
Clearstead Advisors, LLC185$6.00K0.00%
Insight Financial Services200$6.00K0.00%
Umb Bank N A142$4.00K0.00%
Monolith Advisors133$4.00K0.00%
TD Waterhouse Canada Inc.100$3.13K0.00%
Cornerstone Advisory, LLC100$3.00K0.00%
SkyView Investment Advisors, LLC91$3.00K0.00%
CoreCap Advisors, LLC102$3.00K0.00%
Motley Fool Asset Management LLC66$2.00K0.00%
Centerpoint Advisors, LLC68$2.00K0.00%
SRS Capital Advisors, Inc.38$1.00K0.00%
Signet Financial Management, LLC48$1.00K0.00%
Key Financial Inc19$1.00K0.00%
KB Financial Partners, LLC34$1.00K0.00%
Covestor Ltd32$1.00K0.00%
Valley National Advisers Inc11$00.00%
First Bank & Trust15$00.00%

Sold out (39)

Institutions that held Ionis Pharmaceuticals Inc at the end of Q3 2021 and filed for Q4 2021 without it.

Institutions that sold out of IONS in Q4 2021
InstitutionShares, Q3 2021Value, Q3 2021
American Century Companies Inc199,346$6.69M
HRT Financial LP128,087$4.30M
Sabby Management, LLC84,600$2.84M
Arrowstreet Capital, Limited Partnership41,100$1.38M
Simplex Trading, LLC22,512$901.0K
Sphera Funds Management Ltd.22,000$738.0K
Emerald Advisers, LLC16,815$564.0K
AGF Investments LLC15,936$534.0K
Walleye Capital LLC15,470$519.0K
JustInvest LLC13,544$454.0K
HAP Trading, LLC11,877$398.0K
Mackenzie Financial Corp9,783$328.0K
FDx Advisors, Inc.7,507$252.0K
Mitchell & Pahl Private Wealth, LLC6,888$231.0K
Mirae Asset Global Investments Co., Ltd.6,599$221.0K
Prudential Financial Inc5,763$214.0K
Global Retirement Partners, LLC5,784$194.0K
Agf Investments Inc.4,800$161.0K
Advisors Asset Management, Inc.3,164$106.0K
Walled Lake Planning & Wealth Management, LLC1,900$64.0K
Cedar Wealth Management, LLC1,370$46.0K
Antonetti Capital Management LLC1,000$34.0K
Consolidated Planning Corp777$26.0K
Firestone Capital Management250$10.0K
O'Shaughnessy Asset Management, LLC243$8.00K
Federation des caisses Desjardins du Quebec200$6.71K
Eagle Bay Advisors LLC150$6.00K
IAG Wealth Partners, LLC135$5.00K
Whittier Trust Co100$3.00K
JFS Wealth Advisors, LLC75$3.00K
Zions Bancorporation, N.A.83$3.00K
Mitsubishi UFJ Trust & Banking Corp50$2.00K
PSI Advisors, LLC50$2.00K
Covington Capital Management23$1.00K
Stonebridge Capital Advisors LLC29$1.00K
Liberty Wealth Management LLC44$1.00K
Meridian Wealth Partners, LLC23$1.00K
TD Private Client Wealth LLC11$369
Meeder Asset Management Inc14$0

Not filed for Q4 2021 yet (5)

Institutions that held Ionis Pharmaceuticals Inc at the end of Q3 2021 and haven't filed a 13F for Q4 2021. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding IONS in Q3 2021 that haven't filed for Q4 2021
InstitutionShares, Q3 2021Value, Q3 2021
Sonora Investment Management, LLC163,703$5.49M
Alexandria Capital, LLC18,362$616.0K
Optimal Asset Management, Inc.15,118$507.0K
Berman Capital Advisors, LLC1,220$40.0K
Heritage Wealth Management, LLC450$15.0K