Denali Therapeutics Inc.
DNLI- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.
13F holders, Q2 2026
Institutional positions in Denali Therapeutics Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 294
- +28 vs. Q1 2026
- Shares held
- 156.2M
- +8.88M (+6.0%) vs. Q1 2026
- Total value
- $4.00B
- +$1.18B (+41.8%) vs. Q1 2026
- New holders
- 56
- 120 more added
- Sold out
- 28
- 68 more reduced
3 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 294 | $4.00B |
| Q1 2026 | 269 | $2.82B |
| Q4 2025 | 250 | $2.50B |
| Q3 2025 | 240 | $1.97B |
| Q2 2025 | 231 | $1.93B |
| Q1 2025 | 222 | $1.85B |
| Q4 2024 | 224 | $2.61B |
| Q3 2024 | 217 | $3.69B |
| Q2 2024 | 203 | $2.88B |
| Q1 2024 | 211 | $2.51B |
| Q4 2023 | 209 | $2.47B |
| Q3 2023 | 195 | $2.24B |
| Q2 2023 | 203 | $3.18B |
| Q1 2023 | 202 | $2.49B |
| Q4 2022 | 199 | $2.94B |
| Q3 2022 | 200 | $2.84B |
| Q2 2022 | 188 | $2.73B |
| Q1 2022 | 190 | $2.79B |
| Q4 2021 | 213 | $3.80B |
| Q3 2021 | 214 | $4.28B |
| Q2 2021 | 210 | $6.32B |
| Q1 2021 | 218 | $4.60B |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Knights of Columbus Asset Advisors LLC | 67,591 | $1.74M | 0.09% | +11,262+20.0% | Added |
| Citadel Advisors LLC | 66,971 | $1.72M | 0.00% | −114,446−63.1% | Reduced |
| 1492 Capital Management LLC | 66,368 | $1.71M | 0.50% | −1,049−1.6% | Reduced |
| Vanguard Global Advisers, LLC | 61,400 | $1.58M | 0.00% | +2,621+4.5% | Added |
| Jupiter Topco LLC | 60,028 | $1.54M | 0.00% | +60,028 | New |
| Dana Investment Advisors, Inc. | 59,971 | $1.54M | 0.04% | +8,049+15.5% | Added |
| Handelsbanken Fonder AB | 59,600 | $1.53M | 0.00% | +15,800+36.1% | Added |
| SEI Investments Co | 58,989 | $1.52M | 0.00% | +6,754+12.9% | Added |
| Prudential Financial Inc | 58,135 | $1.50M | 0.00% | +27,565+90.2% | Added |
| Engineers Gate Manager LP | 57,430 | $1.48M | 0.02% | +41,320+256.5% | Added |
| Franklin Resources Inc | 56,662 | $1.46M | 0.00% | +7,930+16.3% | Added |
| Pathstone Holdings, LLC | 54,014 | $1.39M | 0.00% | −2,311−4.1% | Reduced |
| Virtus Investment Advisers, Inc. | 53,688 | $1.38M | 0.32% | +38,522+254.0% | Added |
| Wellington Management Group LLP | 52,618 | $1.35M | 0.00% | −745−1.4% | Reduced |
| Ironwood Investment Management LLC | 52,080 | $1.34M | 0.46% | +180.0% | Added |
| Envestnet Asset Management Inc | 51,424 | $1.32M | 0.00% | +524+1.0% | Added |
| Profund Advisors LLC | 49,899 | $1.28M | 0.04% | −18,328−26.9% | Reduced |
| MAI Capital Management | 49,160 | $1.26M | 0.00% | +2,570+5.5% | Added |
| Voya Investment Management LLC | 45,823 | $1.18M | 0.00% | +22,151+93.6% | Added |
| Savvy Advisors, Inc. | 45,194 | $1.16M | 0.02% | +45,194 | New |
| Employees Retirement System of Texas | 44,340 | $1.14M | 0.01% | −2,837−6.0% | Reduced |
| DekaBank Deutsche Girozentrale | 59,800 | $1.13M | 0.00% | 00.0% | Unchanged |
| Raymond James Financial Inc | 43,744 | $1.13M | 0.00% | +9,361+27.2% | Added |
| State of New Jersey Common Pension Fund D | 43,587 | $1.12M | 0.00% | −3,884−8.2% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 43,387 | $1.12M | 0.01% | +4,842+12.6% | Added |
| SG Americas Securities, LLC | 42,339 | $1.09M | 0.00% | −4,303−9.2% | Reduced |
| Tudor Investment Corp Et Al | 40,965 | $1.05M | 0.00% | +40,965 | New |
| Jain Global LLC | 38,435 | $988.5K | 0.01% | +38,435 | New |
| Quantinno Capital Management LP | 37,651 | $968.4K | 0.00% | +7,481+24.8% | Added |
| Vanguard Investments Australia, Ltd. | 37,410 | $962.2K | 0.00% | 00.0% | Unchanged |
| Arizona State Retirement System | 37,196 | $956.7K | 0.00% | −957−2.5% | Reduced |
| Nomura Asset Management Co Ltd | 36,732 | $944.7K | 0.00% | 00.0% | Unchanged |
| Intech Investment Management LLC | 35,484 | $912.6K | 0.01% | −3,447−8.9% | Reduced |
| Jefferies Financial Group Inc. | 34,425 | $885.4K | 0.01% | 00.0% | Unchanged |
| State Board of Administration of Florida Retirement System | 34,168 | $878.8K | 0.00% | 00.0% | Unchanged |
| Mariner, LLC | 32,799 | $843.6K | 0.00% | +14,668+80.9% | Added |
| Thrivent Financial for Lutherans | 32,555 | $837.0K | 0.00% | 00.0% | Unchanged |
| Yorktown Management & Research Co Inc | 32,100 | $825.6K | 0.51% | +32,100 | New |
| J. Safra Sarasin Holding AG | 31,250 | $804.0K | 0.01% | +31,250 | New |
| KLP Kapitalforvaltning AS | 30,900 | $794.7K | 0.00% | 00.0% | Unchanged |
| China Universal Asset Management Co., Ltd. | 29,819 | $766.9K | 0.05% | −10,824−26.6% | Reduced |
| SBI Okasan Asset Management Co.Ltd. | 29,500 | $763.8K | 0.03% | 00.0% | Unchanged |
| Erste Asset Management GmbH | 26,900 | $696.4K | 0.01% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 25,071 | $644.8K | 0.00% | −14,822−37.2% | Reduced |
| ProShare Advisors LLC | 24,466 | $629.3K | 0.00% | −3,271−11.8% | Reduced |
| Simplex Trading, LLC | 23,952 | $616.0K | 0.02% | +11,637+94.5% | Added |
| Cerity Partners LLC | 21,587 | $555.2K | 0.00% | +8,929+70.5% | Added |
| Capstone Investment Advisors, LLC | 20,964 | $539.2K | 0.00% | +8,001+61.7% | Added |
| Ieq Capital, LLC | 20,185 | $519.2K | 0.00% | +20,185 | New |
| Allstate Corp | 19,313 | $496.7K | 0.00% | +19,313 | New |
| Connor, Clark & Lunn Investment Management Ltd. | 18,556 | $477.3K | 0.00% | +18,556 | New |
| Martingale Asset Management L P | 18,530 | $476.6K | 0.01% | −50.0% | Reduced |
| Banque Cantonale Vaudoise | 17,926 | $461.0K | 0.02% | +17,926 | New |
| Fieldview Capital Management, LLC | 17,873 | $459.7K | 0.13% | +17,873 | New |
| State of Wyoming | 17,778 | $457.3K | 0.05% | +17,778 | New |
| Bellevue Group AG | 17,766 | $456.9K | 0.01% | 00.0% | Unchanged |
| Victory Capital Management Inc | 17,197 | $442.3K | 0.00% | +1,003+6.2% | Added |
| Advisor Group Holdings, Inc. | 17,016 | $437.6K | 0.00% | +603+3.7% | Added |
| Intrust Bank NA | 16,477 | $423.8K | 0.03% | +2,138+14.9% | Added |
| Wealth Enhancement Advisory Services, LLC | 16,467 | $422.9K | 0.00% | +16,467 | New |
| Mercer Global Advisors Inc | 16,257 | $418.1K | 0.00% | +16,257 | New |
| Himension Fund | 15,949 | $410.2K | 0.03% | +15,949 | New |
| Teacher Retirement System of Texas | 15,713 | $404.1K | 0.00% | −2,169−12.1% | Reduced |
| Graham Capital Management, L.P. | 15,669 | $403.0K | 0.01% | +15,669 | New |
| Breakwater Capital Group | 15,601 | $401.3K | 0.05% | +15+0.1% | Added |
| Contravisory Investment Management, Inc. | 14,674 | $377.4K | 0.07% | +223+1.5% | Added |
| Xponance, Inc. | 14,616 | $375.9K | 0.00% | +1,376+10.4% | Added |
| Empowered Funds, LLC | 14,428 | $371.1K | 0.00% | −1,359−8.6% | Reduced |
| Virginia Retirement Systems Et Al | 14,300 | $367.8K | 0.00% | +14,300 | New |
| Winton Group Ltd | 14,100 | $362.7K | 0.01% | −57,079−80.2% | Reduced |
| Royal Bank of Canada | 13,974 | $359.0K | 0.00% | +6,439+85.5% | Added |
| LPL Financial LLC | 13,868 | $356.7K | 0.00% | +1,594+13.0% | Added |
| Guggenheim Capital LLC | 13,636 | $350.7K | 0.00% | −189−1.4% | Reduced |
| Inceptionr LLC | 13,632 | $350.6K | 0.09% | +13,632 | New |
| E Fund Management Co., Ltd. | 13,585 | $349.4K | 0.01% | −5,357−28.3% | Reduced |
| Great West Life Assurance Co | 13,434 | $345.0K | 0.00% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 13,351 | $343.4K | 0.01% | +1,697+14.6% | Added |
| National Asset Management, Inc. | 12,813 | $331.7K | 0.02% | +600+4.9% | Added |
| Pier 88 Investment Partners LLC | 12,700 | $326.6K | 0.08% | −52,100−80.4% | Reduced |
| Public Employees Retirement Association of Colorado | 12,238 | $315.0K | 0.00% | 00.0% | Unchanged |
| Atria Investments LLC | 12,130 | $312.0K | 0.00% | +18+0.1% | Added |
| JustInvest LLC | 11,953 | $307.4K | 0.00% | +331+2.8% | Added |
| CI Private Wealth, LLC | 11,704 | $301.0K | 0.00% | +11,704 | New |
| Lynx1 Capital Management LP | 11,658 | $299.8K | 0.03% | −1,868,645−99.4% | Reduced |
| Pinnacle Wealth Planning Services, Inc. | 11,587 | $298.0K | 0.03% | +181+1.6% | Added |
| Cetera Investment Advisers | 11,569 | $297.6K | 0.00% | +510+4.6% | Added |
| Bayforest Capital Ltd | 11,437 | $294.2K | 0.27% | +11,370+16,970.1% | Added |
| Tower Research Capital LLC (TRC) | 11,393 | $293.0K | 0.01% | −9,585−45.7% | Reduced |
| Gilbert & Cook, Inc. | 11,179 | $287.5K | 0.03% | +308+2.8% | Added |
| HighTower Advisors, LLC | 11,020 | $283.4K | 0.00% | −951−7.9% | Reduced |
| Neuberger Berman Group LLC | 9,742 | $250.6K | 0.00% | +9,742 | New |
| The PNC Financial Services Group, Inc. | 9,122 | $234.6K | 0.00% | −98−1.1% | Reduced |
| Swiss Life Asset Management Ltd | 9,091 | $233.8K | 0.00% | +9,091 | New |
| Rockefeller Capital Management L.P. | 8,894 | $228.8K | 0.00% | −17,041−65.7% | Reduced |
| DnB Asset Management AS | 8,581 | $220.7K | 0.00% | −2,378−21.7% | Reduced |
| Mitsubishi UFJ Trust & Banking Corp | 8,494 | $218.5K | 0.00% | +8,494 | New |
| PSP Research LLC | 8,463 | $217.7K | 0.12% | +8,463 | New |
| Mount Yale Investment Advisors, LLC | 8,343 | $214.6K | 0.00% | +8,343 | New |
| MONECO Advisors, LLC | 8,278 | $212.9K | 0.01% | +8,278 | New |
| CIBC Bancorp USA Inc. | 8,122 | $208.9K | 0.00% | +8,122 | New |