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Denali Therapeutics Inc.

DNLI
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001714899

In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Denali Therapeutics Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
294
+28 vs. Q1 2026
Shares held
156.2M
+8.88M (+6.0%) vs. Q1 2026
Total value
$4.00B
+$1.18B (+41.8%) vs. Q1 2026
New holders
56
120 more added
Sold out
28
68 more reduced

3 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 294 institutions
Q1 2021: 218 institutionsQ2 2021: 210 institutionsQ3 2021: 214 institutionsQ4 2021: 213 institutionsQ1 2022: 190 institutionsQ2 2022: 188 institutionsQ3 2022: 200 institutionsQ4 2022: 199 institutionsQ1 2023: 202 institutionsQ2 2023: 203 institutionsQ3 2023: 195 institutionsQ4 2023: 209 institutionsQ1 2024: 211 institutionsQ2 2024: 203 institutionsQ3 2024: 217 institutionsQ4 2024: 224 institutionsQ1 2025: 222 institutionsQ2 2025: 231 institutionsQ3 2025: 240 institutionsQ4 2025: 250 institutionsQ1 2026: 269 institutionsQ2 2026: 294 institutions
Value heldQ2 2026: $4.00B
Q1 2021: $4.60BQ2 2021: $6.32BQ3 2021: $4.28BQ4 2021: $3.80BQ1 2022: $2.79BQ2 2022: $2.73BQ3 2022: $2.84BQ4 2022: $2.94BQ1 2023: $2.49BQ2 2023: $3.18BQ3 2023: $2.24BQ4 2023: $2.47BQ1 2024: $2.51BQ2 2024: $2.88BQ3 2024: $3.69BQ4 2024: $2.61BQ1 2025: $1.85BQ2 2025: $1.93BQ3 2025: $1.97BQ4 2025: $2.50BQ1 2026: $2.82BQ2 2026: $4.00B
Institutions holding DNLI and their total value by quarter
QuarterHoldersValue
Q2 2026294$4.00B
Q1 2026269$2.82B
Q4 2025250$2.50B
Q3 2025240$1.97B
Q2 2025231$1.93B
Q1 2025222$1.85B
Q4 2024224$2.61B
Q3 2024217$3.69B
Q2 2024203$2.88B
Q1 2024211$2.51B
Q4 2023209$2.47B
Q3 2023195$2.24B
Q2 2023203$3.18B
Q1 2023202$2.49B
Q4 2022199$2.94B
Q3 2022200$2.84B
Q2 2022188$2.73B
Q1 2022190$2.79B
Q4 2021213$3.80B
Q3 2021214$4.28B
Q2 2021210$6.32B
Q1 2021218$4.60B

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q1 2026.

Institutions holding DNLI in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Navigoe, LLC3$00.00%+3New
Raffa Wealth Management, LLC1$260.00%00.0%Unchanged
Northwestern Mutual Wealth Management Co1$260.00%+1New
Maryland Capital Advisors Inc.1$260.00%+1New
Silver Grove Financial Group, Inc.1$260.00%+1New
DecisionPoint Financial, LLC2$520.00%+2New
JPL Wealth Management, LLC2$520.00%+2New
Dunhill Financial, LLC2$530.00%00.0%Unchanged
LRI Investments, LLC3$770.00%+3New
Bay Harbor Wealth Management, LLC7$1800.00%+1+16.7%Added
Rialto Wealth Management, LLC7$1810.00%+2+40.0%Added
Cullen/Frost Bankers, Inc.10$2570.00%00.0%Unchanged
Atlantic Private Wealth, LLC10$2570.00%00.0%Unchanged
DiNuzzo Private Wealth, Inc.10$2580.00%+8+400.0%Added
HFM Investment Advisors, LLC11$2830.00%+6+120.0%Added
Basecamp Wealth Advisors LLC17$4370.00%00.0%Unchanged
Creative Capital Management Investments LLC18$4630.00%+18New
Bear Mountain Capital, Inc.22$4940.00%+22New
Keating Financial Advisory Services, Inc.27$6940.00%−6−18.2%Reduced
Action Point Financial Planning, LLC33$8490.00%+33New
Cornerstone Financial Management LLC34$8740.00%00.0%Unchanged
Manchester Capital Management LLC36$9260.00%00.0%Unchanged
Larson Financial Group LLC38$9770.00%−24−38.7%Reduced
Bell Investment Advisors, Inc38$9780.00%00.0%Unchanged
Hantz Financial Services, Inc.57$1.00K0.00%00.0%Unchanged
Avion Wealth40$1.00K0.00%00.0%Unchanged
Transamerica Financial Advisors, Inc.40$1.03K0.00%00.0%Unchanged
Ronald Blue Trust, Inc.40$1.03K0.00%00.0%Unchanged
Caitong International Asset Management Co., Ltd46$1.18K0.00%−15,815−99.7%Reduced
JFS Wealth Advisors, LLC51$1.31K0.00%+43+537.5%Added
Fortitude Family Office, LLC61$1.57K0.00%+26+74.3%Added
Clearstead Advisors, LLC62$1.59K0.00%−737,928−100.0%Reduced
Rossby Financial, LCC65$1.67K0.00%00.0%Unchanged
Wealth Enhancement Trust Services, Inc.65$1.67K0.00%+65New
TD Private Client Wealth LLC71$1.83K0.00%00.0%Unchanged
UMA Financial Services, Inc.76$1.96K0.00%00.0%Unchanged
Johnson Financial Group, Inc.81$2.08K0.00%00.0%Unchanged
CVA Family Office, LLC86$2.21K0.00%+23+36.5%Added
True Wealth Design, LLC88$2.26K0.00%+31+54.4%Added
Jones Financial Companies LLLP104$2.66K0.00%+65+166.7%Added
Ameriflex Group, Inc.104$2.67K0.00%+104New
WPG Advisers, LLC142$3.65K0.00%+76+115.2%Added
Meeder Asset Management Inc142$3.65K0.00%+142New
Massmutual Trust Co FSB143$3.68K0.00%00.0%Unchanged
Parkside Financial Bank & Trust189$4.86K0.00%00.0%Unchanged
Comprehensive Financial Planning, Inc.200$5.14K0.00%00.0%Unchanged
HM Payson & Co200$5.14K0.00%+200New
Parallel Advisors, LLC213$5.48K0.00%−145−40.5%Reduced
EverSource Wealth Advisors, LLC213$5.48K0.00%−43−16.8%Reduced
SJS Investment Consulting Inc.218$5.61K0.00%+202+1,262.5%Added
Signaturefd, LLC230$5.92K0.00%−11−4.6%Reduced
Essential Partners LLC236$6.07K0.00%+191+424.4%Added
City State Bank250$6.43K0.00%00.0%Unchanged
Private Wealth Management Group, LLC296$7.61K0.00%00.0%Unchanged
Steward Partners Investment Advisory, LLC340$8.74K0.00%+204+150.0%Added
Covestor Ltd347$9.00K0.01%+25+7.8%Added
Rothschild Investment LLC437$11.2K0.00%+149+51.7%Added
Huntington National Bank445$11.4K0.00%+25+6.0%Added
Owl Creek Wealth Partners LLC450$11.6K0.00%00.0%Unchanged
IFP Advisors, Inc503$12.9K0.00%+494+5,488.9%Added
Farther Finance Advisors, LLC537$13.8K0.00%+282+110.6%Added
Mowery & Schoenfeld Wealth Management, LLC555$14.3K0.02%+55+11.0%Added
Umb Bank N A624$16.0K0.00%00.0%Unchanged
Los Angeles Capital Management LLC627$16.1K0.00%−300−32.4%Reduced
Nemes Rush Group LLC700$18.0K0.00%00.0%Unchanged
Optiver Holding B.V.776$20.0K0.00%−90−10.4%Reduced
Group One Trading, L.P.776$20.0K0.00%+776New
NBC Securities, Inc.938$24.1K0.00%−6,679−87.7%Reduced
US Bancorp950$24.4K0.00%+48+5.3%Added
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.1,001$25.7K0.00%00.0%Unchanged
Global Retirement Partners, LLC1,103$28.4K0.00%+1,103New
Smartleaf Asset Management LLC1,107$28.7K0.00%00.0%Unchanged
Kemnay Advisory Services Inc.1,304$33.5K0.00%+170+15.0%Added
SBI Securities Co., Ltd.1,448$37.2K0.00%+1,080+293.5%Added
Nykredit A/S1,488$38.3K0.00%+1,488New
Bartlett & Co. Wealth Management LLC1,500$38.6K0.00%00.0%Unchanged
GAMMA Investing LLC1,549$39.8K0.00%+121+8.5%Added
Pacer Advisors, Inc.1,609$41.0K0.00%+1,609New
Versant Capital Management, Inc1,633$42.0K0.00%+157+10.6%Added
SRS Capital Advisors, Inc.1,661$42.7K0.00%+1,360+451.8%Added
Allworth Financial LP1,834$47.2K0.00%+1,554+555.0%Added
Graticule Asia Macro Advisors LLC2,206$56.7K0.00%+2,206New
Sterling Capital Management LLC2,837$73.0K0.00%−1,656−36.9%Reduced
Fifth Third Bancorp3,019$77.7K0.00%+172+6.0%Added
GF Fund Management Co. Ltd.3,357$86.3K0.00%+63+1.9%Added
Nisa Investment Advisors, LLC3,697$95.1K0.00%+1,273+52.5%Added
STRS Ohio4,300$110.6K0.00%+4,300New
KBC Group NV4,943$127.0K0.00%00.0%Unchanged
Eurizon Capital SGR S.p.A.5,045$130.7K0.00%00.0%Unchanged
Assetmark, Inc5,216$134.2K0.00%+17+0.3%Added
Acadian Asset Management LLC6,476$166.0K0.00%+6,476New
Mirae Asset Global Investments Co., Ltd.7,098$182.6K0.00%−1,174−14.2%Reduced
Fox Run Management, L.L.C.7,779$200.1K0.03%+7,779New
Letko, Brosseau & Associates Inc7,850$201.9K0.00%+7,850New
CIBC Bancorp USA Inc.8,122$208.9K0.00%+8,122New
MONECO Advisors, LLC8,278$212.9K0.01%+8,278New
Mount Yale Investment Advisors, LLC8,343$214.6K0.00%+8,343New
PSP Research LLC8,463$217.7K0.12%+8,463New
Mitsubishi UFJ Trust & Banking Corp8,494$218.5K0.00%+8,494New
DnB Asset Management AS8,581$220.7K0.00%−2,378−21.7%Reduced