Denali Therapeutics Inc.
DNLI- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.
13F holders, Q3 2022
Institutional positions in Denali Therapeutics Inc. as of Sep 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 200
- +13 vs. Q2 2022
- Shares held
- 92.4M
- −257.0K (−0.3%) vs. Q2 2022
- Total value
- $2.84B
- +$108.6M (+4.0%) vs. Q2 2022
- New holders
- 32
- 78 more added
- Sold out
- 19
- 56 more reduced
1 institution that held it in Q2 2022 haven't filed for Q3 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 294 | $4.00B |
| Q1 2026 | 269 | $2.82B |
| Q4 2025 | 250 | $2.50B |
| Q3 2025 | 240 | $1.97B |
| Q2 2025 | 231 | $1.93B |
| Q1 2025 | 222 | $1.85B |
| Q4 2024 | 224 | $2.61B |
| Q3 2024 | 217 | $3.69B |
| Q2 2024 | 203 | $2.88B |
| Q1 2024 | 211 | $2.51B |
| Q4 2023 | 209 | $2.47B |
| Q3 2023 | 195 | $2.24B |
| Q2 2023 | 203 | $3.18B |
| Q1 2023 | 202 | $2.49B |
| Q4 2022 | 199 | $2.94B |
| Q3 2022 | 200 | $2.84B |
| Q2 2022 | 188 | $2.73B |
| Q1 2022 | 190 | $2.79B |
| Q4 2021 | 213 | $3.80B |
| Q3 2021 | 214 | $4.28B |
| Q2 2021 | 210 | $6.32B |
| Q1 2021 | 218 | $4.60B |
Institutions, Q3 2022
Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q2 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Baillie Gifford & Co | 14,715,051 | $451.6M | 0.47% | −154,323−1.0% | Reduced |
| BlackRock Inc. | 8,598,212 | $263.9M | 0.01% | −186,420−2.1% | Reduced |
| Vanguard Group Inc | 8,402,031 | $257.9M | 0.01% | +99,530+1.2% | Added |
| Crestline Management, LP | 7,160,732 | $219.8M | 29.71% | −300,000−4.0% | Reduced |
| Temasek Holdings (Private) Ltd | 5,576,041 | $171.1M | 1.02% | +206,554+3.8% | Added |
| State Street Corp | 4,192,228 | $128.7M | 0.01% | +441,528+11.8% | Added |
| ARCH Venture Management, LLC | 3,668,749 | $112.6M | 14.60% | −1,500,000−29.0% | Reduced |
| Price T Rowe Associates Inc | 3,478,368 | $106.8M | 0.02% | −1,131,809−24.6% | Reduced |
| Flagship Pioneering Inc. | 2,619,968 | $80.4M | 3.38% | 00.0% | Unchanged |
| FMR LLC | 2,452,456 | $75.3M | 0.01% | −417,284−14.5% | Reduced |
| Bank of New York Mellon Corp | 1,895,292 | $58.2M | 0.01% | +27,162+1.5% | Added |
| Gilder Gagnon Howe & Co LLC | 1,863,277 | $57.2M | 1.00% | −93,543−4.8% | Reduced |
| Geode Capital Management, LLC | 1,776,164 | $54.5M | 0.01% | +69,583+4.1% | Added |
| Credit Suisse AG | 1,611,429 | $49.5M | 0.06% | −348,596−17.8% | Reduced |
| Yiheng Capital Management, L.P. | 1,014,684 | $31.1M | 2.93% | 00.0% | Unchanged |
| Pictet Asset Management SA | 1,003,185 | $30.8M | 0.05% | −11,973−1.2% | Reduced |
| Casdin Capital, LLC | 995,000 | $30.5M | 2.02% | −505,000−33.7% | Reduced |
| Norges Bank | 943,404 | $29.0M | 0.01% | +111,595+13.4% | Added |
| Northern Trust Corp | 889,968 | $27.3M | 0.01% | −650−0.1% | Reduced |
| Charles Schwab Investment Management Inc | 730,880 | $22.4M | 0.01% | −642−0.1% | Reduced |
| Goldman Sachs Group Inc | 728,272 | $22.4M | 0.01% | +307,530+73.1% | Added |
| Morgan Stanley | 681,332 | $20.9M | 0.00% | +258,321+61.1% | Added |
| Marshall Wace, LLP | 675,870 | $20.7M | 0.05% | −141,780−17.3% | Reduced |
| Federated Hermes, Inc. | 656,593 | $20.2M | 0.06% | −12,336−1.8% | Reduced |
| Point72 Asset Management, L.P. | 633,000 | $19.4M | 0.08% | +633,000 | New |
| Dimensional Fund Advisors LP | 609,839 | $18.7M | 0.01% | −281,839−31.6% | Reduced |
| Artal Group S.A. | 600,000 | $18.4M | 0.96% | 00.0% | Unchanged |
| Baker Bros. Advisors LP | 588,738 | $18.1M | 0.12% | 00.0% | Unchanged |
| Principal Financial Group Inc | 545,871 | $16.8M | 0.01% | +278,139+103.9% | Added |
| UBS Asset Management Americas Inc | 530,204 | $16.3M | 0.01% | +42,799+8.8% | Added |
| Millennium Management LLC | 496,184 | $15.2M | 0.02% | −149,152−23.1% | Reduced |
| American Century Companies Inc | 472,374 | $14.5M | 0.01% | +3,093+0.7% | Added |
| Woodline Partners LP | 444,256 | $13.6M | 0.20% | +263,284+145.5% | Added |
| Artisan Partners Limited Partnership | 443,101 | $13.6M | 0.02% | −7,588−1.7% | Reduced |
| T. Rowe Price Investment Management, Inc. | 422,357 | $13.0M | 0.01% | +422,357 | New |
| Renaissance Technologies LLC | 392,200 | $12.0M | 0.02% | +138,700+54.7% | Added |
| Wasatch Advisors Inc | 359,473 | $11.0M | 0.08% | +17,799+5.2% | Added |
| Candriam Luxembourg S.C.A. | 357,878 | $11.0M | 0.08% | +34,996+10.8% | Added |
| Nuveen Asset Management, LLC | 351,459 | $10.8M | 0.00% | −8,699−2.4% | Reduced |
| Barclays PLC | 325,467 | $9.99M | 0.01% | −43,304−11.7% | Reduced |
| Mitsubishi UFJ Trust & Banking Corp | 307,460 | $9.44M | 0.03% | −7,430−2.4% | Reduced |
| Skandinaviska Enskilda Banken AB (publ) | 291,308 | $8.94M | 0.07% | +78,485+36.9% | Added |
| Bamco Inc | 274,862 | $8.44M | 0.03% | −843−0.3% | Reduced |
| Two Sigma Investments, LP | 261,170 | $8.02M | 0.03% | +196,846+306.0% | Added |
| Clarius Group, LLC | 260,604 | $8.00M | 0.80% | +232,085+813.8% | Added |
| Eagle Asset Management Inc | 255,460 | $7.84M | 0.05% | −8,244−3.1% | Reduced |
| AXA S.A. | 248,772 | $7.63M | 0.03% | +1,081+0.4% | Added |
| Sectoral Asset Management Inc | 243,350 | $7.47M | 1.47% | +41,250+20.4% | Added |
| Tekla Capital Management LLC | 222,420 | $6.83M | 0.28% | 00.0% | Unchanged |
| Bank of America Corp | 220,217 | $6.76M | 0.00% | +101,150+85.0% | Added |
| Rafferty Asset Management, LLC | 207,368 | $6.36M | 0.07% | +105,897+104.4% | Added |
| Swiss National Bank | 204,100 | $6.26M | 0.00% | +2,700+1.3% | Added |
| California Public Employees Retirement System | 199,855 | $6.13M | 0.01% | −2,322−1.1% | Reduced |
| Citigroup Inc | 192,642 | $5.91M | 0.01% | +80,828+72.3% | Added |
| Two Sigma Advisers, LP | 183,800 | $5.64M | 0.02% | +23,300+14.5% | Added |
| Teachers Retirement System of the State of Kentucky | 177,196 | $5.44M | 0.06% | +177,196 | New |
| Voya Investment Management LLC | 165,936 | $5.09M | 0.01% | −64,894−28.1% | Reduced |
| Alliancebernstein L.P. | 154,960 | $4.76M | 0.00% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 144,905 | $4.45M | 0.01% | +4,076+2.9% | Added |
| Rhumbline Advisers | 127,933 | $3.93M | 0.01% | +10,458+8.9% | Added |
| Castleark Management LLC | 127,460 | $3.91M | 0.22% | +127,460 | New |
| Ensign Peak Advisors, Inc | 122,647 | $3.76M | 0.01% | +36,975+43.2% | Added |
| Integral Health Asset Management, LLC | 115,000 | $3.53M | 0.72% | +115,000 | New |
| California State Teachers Retirement System | 112,963 | $3.47M | 0.01% | −1,921−1.7% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 112,532 | $3.45M | 0.02% | +112,532 | New |
| BNP Paribas Arbitrage, SA | 108,569 | $3.33M | 0.01% | +86,237+386.2% | Added |
| JPMorgan Chase & Co | 108,354 | $3.33M | 0.00% | +8,329+8.3% | Added |
| Manufacturers Life Insurance Company, The | 110,257 | $3.29M | 0.00% | −10,030−8.3% | Reduced |
| Russell Investments Group, Ltd. | 106,861 | $3.28M | 0.01% | +18,631+21.1% | Added |
| Jump Financial, LLC | 102,152 | $3.13M | 0.12% | +87,855+614.5% | Added |
| Deutsche Bank AG | 100,850 | $3.10M | 0.00% | −9,447−8.6% | Reduced |
| Edmond de Rothschild Holding S.A. | 99,880 | $3.06M | 0.08% | 00.0% | Unchanged |
| Susquehanna International Group, LLP | 96,627 | $2.97M | 0.01% | +86,101+818.0% | Added |
| TD Asset Management Inc | 94,123 | $2.76M | 0.00% | −27,100−22.4% | Reduced |
| State of Wisconsin Investment Board | 87,556 | $2.69M | 0.01% | +417+0.5% | Added |
| Capital Research Global Investors | 87,767 | $2.65M | 0.00% | +87,767 | New |
| Legal & General Group Plc | 86,017 | $2.64M | 0.00% | −486−0.6% | Reduced |
| Northwest & Ethical Investments L.P. | 79,880 | $2.45M | 0.10% | 00.0% | Unchanged |
| State of New Jersey Common Pension Fund D | 78,253 | $2.40M | 0.01% | −13,645−14.8% | Reduced |
| Invesco Ltd. | 77,895 | $2.39M | 0.00% | +4,229+5.7% | Added |
| HRT Financial LP | 77,628 | $2.38M | 0.03% | +54,028+228.9% | Added |
| Natixis | 69,030 | $2.12M | 0.01% | 00.0% | Unchanged |
| Alps Advisors Inc | 67,323 | $2.07M | 0.02% | −5,617−7.7% | Reduced |
| Wells Fargo & Company | 64,887 | $1.99M | 0.00% | −4,319−6.2% | Reduced |
| Putnam Investments LLC | 64,044 | $1.97M | 0.00% | −232−0.4% | Reduced |
| Citadel Advisors LLC | 63,537 | $1.95M | 0.00% | −242,465−79.2% | Reduced |
| DekaBank Deutsche Girozentrale | 59,800 | $1.74M | 0.01% | 00.0% | Unchanged |
| MetLife Investment Management | 52,427 | $1.61M | 0.01% | +2,035+4.0% | Added |
| Platinum Investment Management Ltd | 50,971 | $1.56M | 0.07% | 00.0% | Unchanged |
| Guggenheim Capital LLC | 50,435 | $1.55M | 0.01% | −10,572−17.3% | Reduced |
| ClariVest Asset Management LLC | 49,380 | $1.51M | 0.07% | −5,258−9.6% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 48,898 | $1.50M | 0.00% | +13,664+38.8% | Added |
| American International Group, Inc. | 46,777 | $1.44M | 0.01% | +661+1.4% | Added |
| Los Angeles Capital Management LLC | 42,741 | $1.31M | 0.01% | −1,178−2.7% | Reduced |
| Toronto Dominion Bank | 42,650 | $1.31M | 0.00% | +42,648+2,132,400.0% | Added |
| UBS Group AG | 42,454 | $1.30M | 0.00% | +36,079+565.9% | Added |
| Voloridge Investment Management, LLC | 42,356 | $1.30M | 0.01% | −5,702−11.9% | Reduced |
| Envestnet Asset Management Inc | 41,516 | $1.27M | 0.00% | +11,073+36.4% | Added |
| Cubist Systematic Strategies, LLC | 38,341 | $1.18M | 0.01% | −33,563−46.7% | Reduced |
| International Biotechnology Trust PLC | 38,000 | $1.17M | 0.37% | +36,882+3,298.9% | Added |