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Denali Therapeutics Inc.

DNLI
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001714899

In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.

13F holders, Q1 2024

Institutional positions in Denali Therapeutics Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
211
+3 vs. Q4 2023
Shares held
122.4M
+7.40M (+6.4%) vs. Q4 2023
Total value
$2.51B
+$47.5M (+1.9%) vs. Q4 2023
New holders
36
76 more added
Sold out
33
69 more reduced

1 institution that held it in Q4 2023 haven't filed for Q1 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2024: 211 institutions
Q1 2021: 218 institutionsQ2 2021: 210 institutionsQ3 2021: 214 institutionsQ4 2021: 213 institutionsQ1 2022: 190 institutionsQ2 2022: 188 institutionsQ3 2022: 200 institutionsQ4 2022: 199 institutionsQ1 2023: 202 institutionsQ2 2023: 203 institutionsQ3 2023: 195 institutionsQ4 2023: 209 institutionsQ1 2024: 211 institutionsQ2 2024: 203 institutionsQ3 2024: 217 institutionsQ4 2024: 224 institutionsQ1 2025: 222 institutionsQ2 2025: 231 institutionsQ3 2025: 240 institutionsQ4 2025: 250 institutionsQ1 2026: 269 institutionsQ2 2026: 294 institutions
Value heldQ1 2024: $2.51B
Q1 2021: $4.60BQ2 2021: $6.32BQ3 2021: $4.28BQ4 2021: $3.80BQ1 2022: $2.79BQ2 2022: $2.73BQ3 2022: $2.84BQ4 2022: $2.94BQ1 2023: $2.49BQ2 2023: $3.18BQ3 2023: $2.24BQ4 2023: $2.47BQ1 2024: $2.51BQ2 2024: $2.88BQ3 2024: $3.69BQ4 2024: $2.61BQ1 2025: $1.85BQ2 2025: $1.93BQ3 2025: $1.97BQ4 2025: $2.50BQ1 2026: $2.82BQ2 2026: $4.00B
Institutions holding DNLI and their total value by quarter
QuarterHoldersValue
Q2 2026294$4.00B
Q1 2026269$2.82B
Q4 2025250$2.50B
Q3 2025240$1.97B
Q2 2025231$1.93B
Q1 2025222$1.85B
Q4 2024224$2.61B
Q3 2024217$3.69B
Q2 2024203$2.88B
Q1 2024211$2.51B
Q4 2023209$2.47B
Q3 2023195$2.24B
Q2 2023203$3.18B
Q1 2023202$2.49B
Q4 2022199$2.94B
Q3 2022200$2.84B
Q2 2022188$2.73B
Q1 2022190$2.79B
Q4 2021213$3.80B
Q3 2021214$4.28B
Q2 2021210$6.32B
Q1 2021218$4.60B

Institutions, Q1 2024

Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q4 2023.

Institutions holding DNLI in Q1 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Baillie Gifford & Co14,041,228$288.1M0.22%−219,496−1.5%Reduced
BlackRock Inc.12,199,856$250.3M0.01%+656,410+5.7%Added
Vanguard Group Inc10,968,293$225.1M0.00%+133,810+1.2%Added
Wellington Management Group LLP8,269,949$169.7M0.03%+995,232+13.7%Added
State Street Corp6,323,872$129.8M0.01%+837,924+15.3%Added
Capital Research Global Investors6,049,957$124.1M0.03%+3,140,429+107.9%Added
Temasek Holdings (Private) Ltd5,706,345$117.1M0.65%−1,189,647−17.3%Reduced
Crestline Management, LP5,210,732$106.9M10.12%−450,000−7.9%Reduced
Takeda Pharmaceutical Co Ltd4,214,559$86.5M29.92%00.0%Unchanged
Baker Bros. Advisors LP3,731,695$76.6M0.96%+1,124,499+43.1%Added
Geode Capital Management, LLC2,759,633$56.6M0.01%+100,337+3.8%Added
Marshall Wace, LLP2,146,379$44.0M0.07%+478,982+28.7%Added
Bank of New York Mellon Corp1,777,907$36.5M0.01%−92,720−5.0%Reduced
Price T Rowe Associates Inc1,594,333$32.7M0.00%−979,988−38.1%Reduced
Credit Suisse AG1,566,246$32.1M0.03%−9,975−0.6%Reduced
Camber Capital Management LP1,500,000$30.8M1.08%+1,500,000New
Citadel Advisors LLC1,365,028$28.0M0.03%+1,296,918+1,904.2%Added
Flagship Pioneering Inc.1,364,516$28.0M1.84%−955,452−41.2%Reduced
Dimensional Fund Advisors LP1,332,950$27.4M0.01%+213,322+19.1%Added
Casdin Capital, LLC1,300,000$26.7M1.99%00.0%Unchanged
Norges Bank1,235,766$25.4M0.00%+83,120+7.2%Added
FMR LLC1,232,522$25.3M0.00%+590,869+92.1%Added
Gilder Gagnon Howe & Co LLC1,172,785$24.1M0.30%−46,607−3.8%Reduced
Yiheng Capital Management, L.P.1,150,684$23.6M3.39%00.0%Unchanged
Principal Financial Group Inc1,122,536$23.0M0.01%+48,832+4.5%Added
Northern Trust Corp1,088,513$22.3M0.00%−13,166−1.2%Reduced
Charles Schwab Investment Management Inc1,041,059$21.4M0.00%+34,062+3.4%Added
Morgan Stanley928,126$19.0M0.00%−49,367−5.1%Reduced
Goldman Sachs Group Inc904,361$18.6M0.00%+510,556+129.6%Added
Holocene Advisors, LP860,948$17.7M0.07%+860,948New
Bank of America Corp851,976$17.5M0.00%+393,338+85.8%Added
UBS Asset Management Americas Inc687,239$14.1M0.01%−21,100−3.0%Reduced
Cercano Management LLC625,000$12.8M0.36%00.0%Unchanged
Standard Life Aberdeen plc516,019$10.6M0.02%+191,190+58.9%Added
Woodline Partners LP508,565$10.4M0.10%+310,981+157.4%Added
Nuveen Asset Management, LLC508,196$10.4M0.00%+188,759+59.1%Added
Artal Group S.A.502,899$10.3M0.27%−300,000−37.4%Reduced
T. Rowe Price Investment Management, Inc.498,969$10.2M0.01%00.0%Unchanged
Fisher Asset Management, LLC469,169$9.63M0.00%+469,169New
American Century Companies Inc459,536$9.43M0.01%−13,958−2.9%Reduced
Polar Capital Holdings Plc452,669$9.29M0.06%00.0%Unchanged
Candriam Luxembourg S.C.A.447,878$9.19M0.06%+90,000+25.1%Added
Rafferty Asset Management, LLC434,909$8.92M0.03%+112,936+35.1%Added
Wasatch Advisors Inc402,670$8.26M0.04%+90,369+28.9%Added
Clarius Group, LLC392,218$8.05M0.56%+13,956+3.7%Added
Millennium Management LLC390,616$8.02M0.01%+390,616New
Citigroup Inc382,416$7.85M0.01%+241,140+170.7%Added
ARCH Venture Management, LLC381,249$7.82M9.75%00.0%Unchanged
Artisan Partners Limited Partnership365,832$7.51M0.01%−18,110−4.7%Reduced
Balyasny Asset Management LLC363,027$7.45M0.02%+102,440+39.3%Added
AXA S.A.360,808$7.40M0.02%+213+0.1%Added
Ensign Peak Advisors, Inc346,304$7.11M0.01%−2,193−0.6%Reduced
UBS Group AG343,879$7.06M0.00%+52,894+18.2%Added
Deutsche Bank AG230,431$4.73M0.00%+115,079+99.8%Added
Voya Investment Management LLC220,638$4.53M0.00%−63,466−22.3%Reduced
Hudson Bay Capital Management LP220,000$4.51M0.04%+45,000+25.7%Added
Swiss National Bank218,200$4.48M0.00%+1,500+0.7%Added
Susquehanna Fundamental Investments, LLC211,017$4.33M0.20%+211,017New
Altitude Crest Partners Inc.209,613$4.30M1.84%+209,613New
Teachers Retirement System of the State of Kentucky207,124$4.25M0.04%−1,520−0.7%Reduced
Edmond de Rothschild Holding S.A.205,680$4.22M0.07%+40,000+24.1%Added
Two Sigma Investments, LP191,505$3.93M0.01%+163,129+574.9%Added
Twinbeech Capital LP177,364$3.64M0.08%+136,784+337.1%Added
Pier Capital, LLC172,331$3.54M0.49%−1,888−1.1%Reduced
Rhumbline Advisers171,959$3.53M0.00%+5,196+3.1%Added
TD Asset Management Inc171,386$3.52M0.00%+80,342+88.2%Added
State of New Jersey Common Pension Fund D165,075$3.39M0.01%+28,475+20.8%Added
PDT Partners, LLC158,384$3.25M0.31%+125,484+381.4%Added
Barclays PLC151,560$3.11M0.00%−172,459−53.2%Reduced
Manufacturers Life Insurance Company, The149,116$3.06M0.00%+47,893+47.3%Added
JPMorgan Chase & Co138,940$2.85M0.00%−44,376−24.2%Reduced
Alliancebernstein L.P.137,620$2.82M0.00%−2,340−1.7%Reduced
Voloridge Investment Management, LLC127,270$2.61M0.01%+127,270New
New York State Common Retirement Fund125,775$2.58M0.00%+1,801+1.5%Added
D. E. Shaw & Co., Inc.116,265$2.39M0.00%+116,265New
Invesco Ltd.114,402$2.35M0.00%+35,263+44.6%Added
Edgestream Partners, L.P.112,118$2.30M0.11%+112,118New
California State Teachers Retirement System111,436$2.29M0.00%−5,915−5.0%Reduced
Legal & General Group Plc107,450$2.20M0.00%+737+0.7%Added
Susquehanna International Group, LLP104,640$2.15M0.00%+43,726+71.8%Added
Alps Advisors Inc98,149$2.01M0.01%+187+0.2%Added
Russell Investments Group, Ltd.85,628$1.76M0.00%−25,845−23.2%Reduced
Algert Global LLC82,000$1.68M0.07%+82,000New
BIT Capital GmbH82,000$1.68M0.15%+82,000New
Prudential Financial Inc80,429$1.65M0.00%−815−1.0%Reduced
State of Wisconsin Investment Board80,393$1.65M0.00%−11,128−12.2%Reduced
Mirae Asset Global Investments Co., Ltd.71,142$1.58M0.00%−2,443−3.3%Reduced
Northwest & Ethical Investments L.P.75,835$1.56M0.04%+4,551+6.4%Added
BNP Paribas Arbitrage, SA72,105$1.48M0.00%−119,538−62.4%Reduced
Tudor Investment Corp Et Al71,651$1.47M0.02%+71,651New
Jefferies Financial Group Inc.69,314$1.42M0.03%−96,013−58.1%Reduced
Profund Advisors LLC68,474$1.41M0.05%+14,799+27.6%Added
Nisa Investment Advisors, LLC66,129$1.36M0.01%+70+0.1%Added
Squarepoint Ops LLC64,874$1.33M0.01%+50,555+353.1%Added
Thrivent Financial for Lutherans64,775$1.33M0.00%+35,093+118.2%Added
Wells Fargo & Company64,783$1.33M0.00%−1,582−2.4%Reduced
DekaBank Deutsche Girozentrale64,210$1.32M0.00%00.0%Unchanged
MetLife Investment Management62,264$1.28M0.01%00.0%Unchanged
AIA Group Ltd61,034$1.25M0.04%−7,044−10.3%Reduced
American International Group, Inc.58,847$1.21M0.00%+122+0.2%Added