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Denali Therapeutics Inc.

DNLI
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001714899

In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.

13F holders, Q2 2023

Institutional positions in Denali Therapeutics Inc. as of Jun 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
203
+2 vs. Q1 2023
Shares held
108.0M
−73.4K (−0.1%) vs. Q1 2023
Total value
$3.18B
+$693.8M (+27.9%) vs. Q1 2023
New holders
27
84 more added
Sold out
25
55 more reduced

1 institution that held it in Q1 2023 haven't filed for Q2 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2023: 203 institutions
Q1 2021: 218 institutionsQ2 2021: 210 institutionsQ3 2021: 214 institutionsQ4 2021: 213 institutionsQ1 2022: 190 institutionsQ2 2022: 188 institutionsQ3 2022: 200 institutionsQ4 2022: 199 institutionsQ1 2023: 202 institutionsQ2 2023: 203 institutionsQ3 2023: 195 institutionsQ4 2023: 209 institutionsQ1 2024: 211 institutionsQ2 2024: 203 institutionsQ3 2024: 217 institutionsQ4 2024: 224 institutionsQ1 2025: 222 institutionsQ2 2025: 231 institutionsQ3 2025: 240 institutionsQ4 2025: 250 institutionsQ1 2026: 269 institutionsQ2 2026: 294 institutions
Value heldQ2 2023: $3.18B
Q1 2021: $4.60BQ2 2021: $6.32BQ3 2021: $4.28BQ4 2021: $3.80BQ1 2022: $2.79BQ2 2022: $2.73BQ3 2022: $2.84BQ4 2022: $2.94BQ1 2023: $2.49BQ2 2023: $3.18BQ3 2023: $2.24BQ4 2023: $2.47BQ1 2024: $2.51BQ2 2024: $2.88BQ3 2024: $3.69BQ4 2024: $2.61BQ1 2025: $1.85BQ2 2025: $1.93BQ3 2025: $1.97BQ4 2025: $2.50BQ1 2026: $2.82BQ2 2026: $4.00B
Institutions holding DNLI and their total value by quarter
QuarterHoldersValue
Q2 2026294$4.00B
Q1 2026269$2.82B
Q4 2025250$2.50B
Q3 2025240$1.97B
Q2 2025231$1.93B
Q1 2025222$1.85B
Q4 2024224$2.61B
Q3 2024217$3.69B
Q2 2024203$2.88B
Q1 2024211$2.51B
Q4 2023209$2.47B
Q3 2023195$2.24B
Q2 2023203$3.18B
Q1 2023202$2.49B
Q4 2022199$2.94B
Q3 2022200$2.84B
Q2 2022188$2.73B
Q1 2022190$2.79B
Q4 2021213$3.80B
Q3 2021214$4.28B
Q2 2021210$6.32B
Q1 2021218$4.60B

Institutions, Q2 2023

Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q1 2023.

Institutions holding DNLI in Q2 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Baillie Gifford & Co14,843,770$438.0M0.37%−508,341−3.3%Reduced
Vanguard Group Inc10,242,983$302.3M0.01%+124,490+1.2%Added
BlackRock Inc.10,106,275$298.2M0.01%+631,878+6.7%Added
Wellington Management Group LLP7,038,176$207.7M0.04%+1,837,716+35.3%Added
Temasek Holdings (Private) Ltd6,895,992$203.5M1.18%00.0%Unchanged
Crestline Management, LP6,110,732$180.3M19.62%−300,000−4.7%Reduced
State Street Corp4,468,491$131.9M0.01%−122,898−2.7%Reduced
Price T Rowe Associates Inc3,445,312$101.7M0.01%−92,466−2.6%Reduced
Capital Research Global Investors2,837,652$83.7M0.02%+368,828+14.9%Added
Flagship Pioneering Inc.2,619,968$77.3M3.45%00.0%Unchanged
Geode Capital Management, LLC2,318,297$68.4M0.01%+172,125+8.0%Added
Bank of New York Mellon Corp1,989,707$58.7M0.01%−26,916−1.3%Reduced
Gilder Gagnon Howe & Co LLC1,579,945$46.6M0.64%−76,452−4.6%Reduced
Credit Suisse AG1,573,048$46.4M0.05%+19,576+1.3%Added
Baker Bros. Advisors LP1,455,322$42.9M0.25%+366,584+33.7%Added
Casdin Capital, LLC1,300,000$38.4M3.35%00.0%Unchanged
Yiheng Capital Management, L.P.1,150,684$34.0M2.95%+136,000+13.4%Added
Northern Trust Corp1,089,698$32.2M0.01%+71,694+7.0%Added
FMR LLC1,079,857$31.9M0.00%−13,707−1.3%Reduced
Morgan Stanley1,076,886$31.8M0.00%+507,764+89.2%Added
Federated Hermes, Inc.1,063,500$31.4M0.08%00.0%Unchanged
Pictet Asset Management SA1,027,977$30.3M0.04%−220,513−17.7%Reduced
Polar Capital Holdings Plc1,007,086$29.7M0.20%+502,086+99.4%Added
Charles Schwab Investment Management Inc867,631$25.6M0.01%+31,303+3.7%Added
Wasatch Advisors Inc832,297$24.6M0.15%+274,130+49.1%Added
Artal Group S.A.802,899$23.7M0.76%00.0%Unchanged
Dimensional Fund Advisors LP754,801$22.3M0.01%+127,476+20.3%Added
ARCH Venture Management, LLC693,749$20.5M12.64%−1,875,000−73.0%Reduced
Principal Financial Group Inc686,492$20.3M0.01%+197,531+40.4%Added
T. Rowe Price Investment Management, Inc.647,013$19.1M0.01%00.0%Unchanged
Goldman Sachs Group Inc644,914$19.0M0.00%+72,071+12.6%Added
Cercano Management LLC625,000$18.4M0.64%00.0%Unchanged
Deerfield Management Company, L.P. (Series C)594,989$17.6M0.37%00.0%Unchanged
Norges Bank580,334$17.1M0.00%−389,106−40.1%Reduced
Man Group plc505,214$14.9M0.05%+505,214New
Millennium Management LLC478,186$14.1M0.01%+91,897+23.8%Added
American Century Companies Inc473,909$14.0M0.01%+1260.0%Added
Renaissance Technologies LLC467,800$13.8M0.02%+59,700+14.6%Added
UBS Asset Management Americas Inc567,141$13.1M0.01%00.0%Unchanged
Artisan Partners Limited Partnership416,783$12.3M0.02%−6,882−1.6%Reduced
Clarius Group, LLC378,267$11.2M0.86%+87,937+30.3%Added
Nuveen Asset Management, LLC365,456$10.8M0.00%+4,820+1.3%Added
AXA S.A.358,382$10.6M0.04%+69,140+23.9%Added
Candriam Luxembourg S.C.A.357,878$10.6M0.08%00.0%Unchanged
Skandinaviska Enskilda Banken AB (publ)348,203$10.3M0.07%+41,233+13.4%Added
Tekla Capital Management LLC324,829$9.59M0.38%00.0%Unchanged
Eventide Asset Management, LLC313,407$9.25M0.16%00.0%Unchanged
Eagle Asset Management Inc294,791$8.70M0.05%−8,170−2.7%Reduced
Mitsubishi UFJ Trust & Banking Corp289,580$8.55M0.02%−15,050−4.9%Reduced
Avidity Partners Management LP282,752$8.34M0.29%+282,752New
Bank of America Corp270,245$7.97M0.00%−149,591−35.6%Reduced
Voya Investment Management LLC263,507$7.78M0.01%+71,779+37.4%Added
Rafferty Asset Management, LLC248,526$7.33M0.04%−8,447−3.3%Reduced
Sectoral Asset Management Inc245,291$7.24M1.21%+441+0.2%Added
Swiss National Bank238,100$7.03M0.00%+32,900+16.0%Added
Point72 Asset Management, L.P.223,471$6.59M0.02%+223,471New
Teachers Retirement System of the State of Kentucky219,448$6.48M0.06%−2,052−0.9%Reduced
International Biotechnology Trust PLC188,000$5.54M1.69%+101,425+117.2%Added
Alliancebernstein L.P.178,720$5.27M0.00%+8,560+5.0%Added
California Public Employees Retirement System176,131$5.20M0.00%00.0%Unchanged
Wells Fargo & Company162,554$4.80M0.00%+37,484+30.0%Added
Rhumbline Advisers161,982$4.78M0.01%+15,840+10.8%Added
Barclays PLC158,462$4.68M0.00%−497,965−75.9%Reduced
JPMorgan Chase & Co157,992$4.66M0.00%+12,005+8.2%Added
Ensign Peak Advisors, Inc148,497$4.38M0.01%+3,950+2.7%Added
Deutsche Bank AG144,877$4.28M0.00%+14,148+10.8%Added
California State Teachers Retirement System135,515$4.00M0.01%+11,503+9.3%Added
UBS Group AG131,940$3.89M0.00%+4,589+3.6%Added
Pier Capital, LLC127,128$3.75M0.54%+127,128New
New York State Common Retirement Fund125,899$3.72M0.00%−8,995−6.7%Reduced
Prudential Financial Inc124,322$3.67M0.01%+115,142+1,254.3%Added
Manufacturers Life Insurance Company, The118,949$3.51M0.00%+3,766+3.3%Added
Susquehanna International Group, LLP117,592$3.47M0.01%−222,972−65.5%Reduced
Woodline Partners LP112,212$3.31M0.04%+11,901+11.9%Added
Citigroup Inc108,027$3.19M0.00%−100,313−48.1%Reduced
BNP Paribas Arbitrage, SA107,482$3.17M0.01%−30,590−22.2%Reduced
Russell Investments Group, Ltd.106,814$3.15M0.01%+24,519+29.8%Added
Legal & General Group Plc104,892$3.10M0.00%+7,274+7.5%Added
Alps Advisors Inc100,620$2.97M0.03%+10,575+11.7%Added
Edmond de Rothschild Holding S.A.99,880$2.95M0.06%00.0%Unchanged
State of Wisconsin Investment Board98,589$2.91M0.01%+10,763+12.3%Added
Invesco Ltd.92,921$2.74M0.00%+9,984+12.0%Added
Susquehanna Fundamental Investments, LLC91,249$2.69M0.10%00.0%Unchanged
TCW Group Inc89,971$2.66M0.03%+1,660+1.9%Added
TD Asset Management Inc84,422$2.49M0.00%−3,900−4.4%Reduced
State of New Jersey Common Pension Fund D78,253$2.31M0.01%00.0%Unchanged
Northwest & Ethical Investments L.P.74,768$2.21M0.07%−17,729−19.2%Reduced
Jane Street Group, LLC72,800$2.15M0.00%−43,005−37.1%Reduced
Mirae Asset Global Investments Co., Ltd.69,678$2.05M0.00%+2,700+4.0%Added
Trexquant Investment LP66,935$1.98M0.05%−13,589−16.9%Reduced
MetLife Investment Management62,264$1.84M0.01%+5,237+9.2%Added
DekaBank Deutsche Girozentrale59,800$1.75M0.00%00.0%Unchanged
American International Group, Inc.56,866$1.68M0.01%+4,336+8.3%Added
AIA Group Ltd56,244$1.66M0.08%+5,980+11.9%Added
Citadel Advisors LLC56,103$1.66M0.00%−1,318,222−95.9%Reduced
Platinum Investment Management Ltd55,341$1.63M0.06%00.0%Unchanged
HighTower Advisors, LLC54,517$1.61M0.00%+2,813+5.4%Added
Guggenheim Capital LLC53,786$1.59M0.01%−2,458−4.4%Reduced
Janus Henderson Group PLC52,754$1.55M0.00%+10,586+25.1%Added
Hamilton Lane Advisors LLC52,129$1.54M0.68%+52,129New