Denali Therapeutics Inc.
DNLI- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.
13F holders, Q4 2021
Institutional positions in Denali Therapeutics Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 213
- +2 vs. Q3 2021
- Shares held
- 85.3M
- +675.1K (+0.8%) vs. Q3 2021
- Total value
- $3.80B
- −$465.4M (−10.9%) vs. Q3 2021
- New holders
- 29
- 86 more added
- Sold out
- 27
- 62 more reduced
3 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 294 | $4.00B |
| Q1 2026 | 269 | $2.82B |
| Q4 2025 | 250 | $2.50B |
| Q3 2025 | 240 | $1.97B |
| Q2 2025 | 231 | $1.93B |
| Q1 2025 | 222 | $1.85B |
| Q4 2024 | 224 | $2.61B |
| Q3 2024 | 217 | $3.69B |
| Q2 2024 | 203 | $2.88B |
| Q1 2024 | 211 | $2.51B |
| Q4 2023 | 209 | $2.47B |
| Q3 2023 | 195 | $2.24B |
| Q2 2023 | 203 | $3.18B |
| Q1 2023 | 202 | $2.49B |
| Q4 2022 | 199 | $2.94B |
| Q3 2022 | 200 | $2.84B |
| Q2 2022 | 188 | $2.73B |
| Q1 2022 | 190 | $2.79B |
| Q4 2021 | 213 | $3.80B |
| Q3 2021 | 214 | $4.28B |
| Q2 2021 | 210 | $6.32B |
| Q1 2021 | 218 | $4.60B |
Institutions, Q4 2021
Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q3 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Baillie Gifford & Co | 15,056,381 | $671.5M | 0.37% | +46,565+0.3% | Added |
| Vanguard Group Inc | 8,161,530 | $364.0M | 0.01% | −6,953−0.1% | Reduced |
| BlackRock Inc. | 8,110,822 | $361.7M | 0.01% | +549,985+7.3% | Added |
| Crestline Management, LP | 7,705,039 | $343.6M | 25.82% | 00.0% | Unchanged |
| Temasek Holdings (Private) Ltd | 5,369,487 | $239.5M | 0.86% | 00.0% | Unchanged |
| Price T Rowe Associates Inc | 4,635,433 | $206.7M | 0.02% | −122,532−2.6% | Reduced |
| State Street Corp | 3,027,571 | $135.0M | 0.01% | +229,437+8.2% | Added |
| FMR LLC | 2,951,791 | $131.7M | 0.01% | +276,042+10.3% | Added |
| Gilder Gagnon Howe & Co LLC | 2,900,114 | $129.3M | 0.74% | +97,120+3.5% | Added |
| Flagship Pioneering Inc. | 2,619,968 | $116.9M | 1.81% | −110,295−4.0% | Reduced |
| Credit Suisse AG | 1,963,648 | $87.6M | 0.07% | −18,825−0.9% | Reduced |
| Geode Capital Management, LLC | 1,628,867 | $72.6M | 0.01% | +21,473+1.3% | Added |
| Casdin Capital, LLC | 1,500,000 | $66.9M | 1.89% | −200,000−11.8% | Reduced |
| Pictet Asset Management SA | 998,620 | $44.5M | 0.04% | +130,117+15.0% | Added |
| Bamco Inc | 996,304 | $44.4M | 0.09% | −131,615−11.7% | Reduced |
| Northern Trust Corp | 959,089 | $42.8M | 0.01% | +7,364+0.8% | Added |
| Bank of New York Mellon Corp | 932,592 | $41.6M | 0.01% | +555,873+147.6% | Added |
| Norges Bank | 846,109 | $37.7M | 0.01% | −7,247−0.8% | Reduced |
| Dimensional Fund Advisors LP | 772,197 | $34.4M | 0.01% | +137,462+21.7% | Added |
| Federated Hermes, Inc. | 735,432 | $32.8M | 0.06% | +396,272+116.8% | Added |
| Charles Schwab Investment Management Inc | 717,190 | $32.0M | 0.01% | +13,438+1.9% | Added |
| Artal Group S.A. | 600,000 | $26.8M | 0.79% | +100,000+20.0% | Added |
| American Century Companies Inc | 536,282 | $23.9M | 0.02% | +187,295+53.7% | Added |
| Artisan Partners Limited Partnership | 521,408 | $23.3M | 0.03% | −29,579−5.4% | Reduced |
| Citadel Advisors LLC | 485,683 | $21.7M | 0.02% | +422,672+670.8% | Added |
| UBS Asset Management Americas Inc | 440,036 | $19.6M | 0.01% | +5,302+1.2% | Added |
| Goldman Sachs Group Inc | 410,764 | $18.3M | 0.00% | −645,794−61.1% | Reduced |
| Marshall Wace, LLP | 383,944 | $17.1M | 0.03% | −147,414−27.7% | Reduced |
| Nuveen Asset Management, LLC | 377,044 | $16.8M | 0.00% | +11,966+3.3% | Added |
| Yiheng Capital Management, L.P. | 335,184 | $14.9M | 0.76% | +335,184 | New |
| Principal Financial Group Inc | 330,275 | $14.7M | 0.01% | +26,448+8.7% | Added |
| Mitsubishi UFJ Trust & Banking Corp | 309,040 | $13.8M | 0.03% | −29,690−8.8% | Reduced |
| Natixis | 293,554 | $13.1M | 0.04% | +14,300+5.1% | Added |
| Morgan Stanley | 287,258 | $12.8M | 0.00% | −96,735−25.2% | Reduced |
| Two Sigma Advisers, LP | 269,600 | $12.0M | 0.03% | −151,500−36.0% | Reduced |
| Jennison Associates LLC | 224,184 | $10.0M | 0.01% | −4,238−1.9% | Reduced |
| Tekla Capital Management LLC | 222,420 | $9.92M | 0.32% | 00.0% | Unchanged |
| AXA S.A. | 220,066 | $9.81M | 0.03% | +18,486+9.2% | Added |
| Prudential Financial Inc | 215,801 | $9.71M | 0.01% | +28,339+15.1% | Added |
| California Public Employees Retirement System | 202,177 | $9.02M | 0.01% | +803+0.4% | Added |
| Eagle Asset Management Inc | 191,516 | $8.63M | 0.04% | −51,029−21.0% | Reduced |
| Sectoral Asset Management Inc | 189,600 | $8.46M | 1.27% | +62,100+48.7% | Added |
| Wasatch Advisors Inc | 174,242 | $7.77M | 0.03% | −286−0.2% | Reduced |
| Swiss National Bank | 173,700 | $7.75M | 0.00% | −400−0.2% | Reduced |
| Teachers Retirement System of the State of Kentucky | 171,496 | $7.65M | 0.07% | 00.0% | Unchanged |
| Alliancebernstein L.P. | 154,660 | $6.90M | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 143,536 | $6.40M | 0.00% | −21,209−12.9% | Reduced |
| Candriam Luxembourg S.C.A. | 141,507 | $6.31M | 0.04% | +77,726+121.9% | Added |
| Skandinaviska Enskilda Banken AB (publ) | 138,563 | $6.24M | 0.03% | +6,509+4.9% | Added |
| New York State Common Retirement Fund | 134,787 | $6.01M | 0.01% | −22,106−14.1% | Reduced |
| Bank of America Corp | 128,948 | $5.75M | 0.00% | +51,102+65.6% | Added |
| TD Asset Management Inc | 122,337 | $5.46M | 0.00% | −4,500−3.5% | Reduced |
| State of Wisconsin Investment Board | 121,800 | $5.43M | 0.01% | −2,200−1.8% | Reduced |
| Rafferty Asset Management, LLC | 121,755 | $5.43M | 0.03% | +61,394+101.7% | Added |
| Barclays PLC | 120,821 | $5.39M | 0.00% | +49,856+70.3% | Added |
| Citigroup Inc | 120,381 | $5.37M | 0.00% | +11,356+10.4% | Added |
| Susquehanna International Group, LLP | 118,895 | $5.30M | 0.01% | +66,798+128.2% | Added |
| Deutsche Bank AG | 118,332 | $5.28M | 0.00% | +2,316+2.0% | Added |
| California State Teachers Retirement System | 116,515 | $5.20M | 0.01% | +2,780+2.4% | Added |
| AIA Group Ltd | 107,842 | $4.81M | 0.23% | +9,401+9.5% | Added |
| Ensign Peak Advisors, Inc | 104,456 | $4.66M | 0.01% | +38,108+57.4% | Added |
| Janus Henderson Group PLC | 100,463 | $4.48M | 0.00% | +92,593+1,176.5% | Added |
| Integral Health Asset Management, LLC | 100,000 | $4.46M | 1.24% | +25,000+33.3% | Added |
| Edmond de Rothschild Holding S.A. | 99,880 | $4.46M | 0.10% | −120−0.1% | Reduced |
| Rhumbline Advisers | 96,649 | $4.31M | 0.01% | −756−0.8% | Reduced |
| UBS Group AG | 92,348 | $4.12M | 0.00% | +27,868+43.2% | Added |
| Baker Bros. Advisors LP | 88,738 | $3.96M | 0.02% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 83,145 | $3.71M | 0.00% | −15,365−15.6% | Reduced |
| Legal & General Group Plc | 78,971 | $3.52M | 0.00% | +1,443+1.9% | Added |
| Goldstream Capital Management Ltd | 78,418 | $3.50M | 0.86% | +78,418 | New |
| Putnam Investments LLC | 76,860 | $3.43M | 0.00% | +5,159+7.2% | Added |
| Russell Investments Group, Ltd. | 66,121 | $2.95M | 0.00% | +770+1.2% | Added |
| ClariVest Asset Management LLC | 65,638 | $2.93M | 0.09% | −5,828−8.2% | Reduced |
| State of New Jersey Common Pension Fund D | 59,618 | $2.66M | 0.01% | +5,310+9.8% | Added |
| Renaissance Technologies LLC | 54,300 | $2.42M | 0.00% | −41,300−43.2% | Reduced |
| Tygh Capital Management, Inc. | 54,226 | $2.42M | 0.31% | −109−0.2% | Reduced |
| Polar Capital Holdings Plc | 53,835 | $2.40M | 0.01% | 00.0% | Unchanged |
| DekaBank Deutsche Girozentrale | 54,400 | $2.37M | 0.01% | +1,500+2.8% | Added |
| Woodline Partners LP | 52,454 | $2.34M | 0.03% | +52,454 | New |
| AQR Capital Management LLC | 51,667 | $2.30M | 0.00% | −30,382−37.0% | Reduced |
| Platinum Investment Management Ltd | 50,971 | $2.27M | 0.06% | +20,180+65.5% | Added |
| Jupiter Asset Management Ltd | 50,023 | $2.25M | 0.02% | 00.0% | Unchanged |
| American International Group, Inc. | 48,350 | $2.16M | 0.01% | −1,447−2.9% | Reduced |
| Guggenheim Capital LLC | 46,982 | $2.10M | 0.01% | +46,982 | New |
| Manufacturers Life Insurance Company, The | 46,496 | $2.09M | 0.00% | −439−0.9% | Reduced |
| Invesco Ltd. | 44,464 | $1.98M | 0.00% | −3,754−7.8% | Reduced |
| Macquarie Group Ltd | 42,161 | $1.88M | 0.00% | +251+0.6% | Added |
| Los Angeles Capital Management LLC | 41,092 | $1.83M | 0.01% | −430−1.0% | Reduced |
| Mark Asset Management LP | 40,370 | $1.80M | 0.26% | +19,841+96.6% | Added |
| ProShare Advisors LLC | 39,402 | $1.76M | 0.00% | −435−1.1% | Reduced |
| Allspring Global Investments Holdings, LLC | 38,612 | $1.72M | 0.00% | +38,612 | New |
| Allianz Asset Management GmbH | 36,145 | $1.61M | 0.00% | +17,410+92.9% | Added |
| Voya Investment Management LLC | 35,073 | $1.56M | 0.00% | −518−1.5% | Reduced |
| Pier 88 Investment Partners LLC | 33,080 | $1.48M | 0.31% | +14,200+75.2% | Added |
| SG Americas Securities, LLC | 32,802 | $1.46M | 0.01% | +1,907+6.2% | Added |
| Parametric Portfolio Associates LLC | 32,444 | $1.45M | 0.00% | −554−1.7% | Reduced |
| MetLife Investment Management | 32,389 | $1.44M | 0.01% | 00.0% | Unchanged |
| Northwest & Ethical Investments L.P. | 31,600 | $1.41M | 0.04% | +31,600 | New |
| STRS Ohio | 30,900 | $1.38M | 0.00% | 00.0% | Unchanged |
| State Board of Administration of Florida Retirement System | 30,468 | $1.36M | 0.00% | +449+1.5% | Added |