Denali Therapeutics Inc.
DNLI- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.
13F holders, Q4 2021
Institutional positions in Denali Therapeutics Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 213
- +2 vs. Q3 2021
- Shares held
- 85.3M
- +675.1K (+0.8%) vs. Q3 2021
- Total value
- $3.80B
- −$465.4M (−10.9%) vs. Q3 2021
- New holders
- 29
- 86 more added
- Sold out
- 27
- 62 more reduced
3 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 294 | $4.00B |
| Q1 2026 | 269 | $2.82B |
| Q4 2025 | 250 | $2.50B |
| Q3 2025 | 240 | $1.97B |
| Q2 2025 | 231 | $1.93B |
| Q1 2025 | 222 | $1.85B |
| Q4 2024 | 224 | $2.61B |
| Q3 2024 | 217 | $3.69B |
| Q2 2024 | 203 | $2.88B |
| Q1 2024 | 211 | $2.51B |
| Q4 2023 | 209 | $2.47B |
| Q3 2023 | 195 | $2.24B |
| Q2 2023 | 203 | $3.18B |
| Q1 2023 | 202 | $2.49B |
| Q4 2022 | 199 | $2.94B |
| Q3 2022 | 200 | $2.84B |
| Q2 2022 | 188 | $2.73B |
| Q1 2022 | 190 | $2.79B |
| Q4 2021 | 213 | $3.80B |
| Q3 2021 | 214 | $4.28B |
| Q2 2021 | 210 | $6.32B |
| Q1 2021 | 218 | $4.60B |
Institutions, Q4 2021
Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q3 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Ellevest, Inc. | 11 | $0 | 0.00% | −4−26.7% | Reduced |
| Bell Investment Advisors, Inc | 11 | $0 | 0.00% | −13−54.2% | Reduced |
| Ci Investments Inc. | 4 | $0 | 0.00% | 00.0% | Unchanged |
| Toronto Dominion Bank | 2 | $0 | 0.00% | +2 | New |
| Schubert & Co | 6 | $0 | 0.00% | +6 | New |
| JFS Wealth Advisors, LLC | 14 | $1.00K | 0.00% | +14 | New |
| Parallel Advisors, LLC | 46 | $2.00K | 0.00% | +20+76.9% | Added |
| EverSource Wealth Advisors, LLC | 51 | $2.00K | 0.00% | +51 | New |
| Farmers & Merchants Investments Inc | 58 | $3.00K | 0.00% | 00.0% | Unchanged |
| Asset Management One Co.,Ltd. | 100 | $4.00K | 0.00% | 00.0% | Unchanged |
| Your Advocates Ltd., LLP | 100 | $4.00K | 0.00% | +100 | New |
| Leonteq Securities AG | 98 | $4.37K | 0.00% | +33+50.8% | Added |
| Smith Group Asset Management, LLC | 110 | $5.00K | 0.00% | 00.0% | Unchanged |
| Captrust Financial Advisors | 119 | $5.00K | 0.00% | +119 | New |
| Private Capital Group, LLC | 132 | $6.00K | 0.00% | −167−55.9% | Reduced |
| Huntington National Bank | 131 | $6.00K | 0.00% | +1+0.8% | Added |
| Activest Wealth Management | 131 | $6.00K | 0.00% | 00.0% | Unchanged |
| Bedel Financial Consulting, Inc. | 154 | $7.00K | 0.00% | 00.0% | Unchanged |
| Covestor Ltd | 155 | $7.00K | 0.01% | +155 | New |
| First Horizon Advisors, Inc. | 215 | $9.00K | 0.00% | 00.0% | Unchanged |
| TCI Wealth Advisors, Inc. | 216 | $10.0K | 0.00% | +59+37.6% | Added |
| City State Bank | 250 | $11.0K | 0.01% | +250 | New |
| Daiwa Securities Group Inc. | 356 | $16.0K | 0.00% | −61−14.6% | Reduced |
| State of Wyoming | 386 | $18.0K | 0.01% | +316+451.4% | Added |
| US Bancorp | 444 | $20.0K | 0.00% | +6+1.4% | Added |
| Snowden Capital Advisors LLC | 500 | $22.0K | 0.00% | +500 | New |
| Dark Forest Capital Management LP | 529 | $24.0K | 0.01% | −66−11.1% | Reduced |
| HM Payson & Co | 578 | $26.0K | 0.00% | +578 | New |
| Lindbrook Capital, LLC | 611 | $27.0K | 0.00% | +611 | New |
| Patriot Financial Group Insurance Agency, LLC | 811 | $36.0K | 0.01% | +451+125.3% | Added |
| Point72 Hong Kong Ltd | 1,319 | $59.0K | 0.00% | +420+46.7% | Added |
| The PNC Financial Services Group, Inc. | 1,452 | $65.0K | 0.00% | +241+19.9% | Added |
| Cutler Group LP | 1,700 | $75.0K | 0.01% | +540+46.6% | Added |
| Itau Unibanco Holding S.A. | 1,948 | $88.0K | 0.00% | +1,569+414.0% | Added |
| Advisor Group Holdings, Inc. | 2,103 | $95.0K | 0.00% | +542+34.7% | Added |
| Amundi | 3,017 | $102.0K | 0.00% | 00.0% | Unchanged |
| High Net Worth Advisory Group LLC | 2,500 | $112.0K | 0.04% | +2,500 | New |
| Nisa Investment Advisors, LLC | 3,851 | $132.0K | 0.00% | −2,295−37.3% | Reduced |
| Compagnie Lombard Odier SCmA | 3,000 | $134.0K | 0.00% | 00.0% | Unchanged |
| Virtus ETF Advisers LLC | 3,633 | $162.0K | 0.06% | +803+28.4% | Added |
| Quantbot Technologies LP | 3,742 | $166.0K | 0.01% | +3,311+768.2% | Added |
| DuPont Capital Management Corp | 4,320 | $193.0K | 0.01% | −3,807−46.8% | Reduced |
| Great West Life Assurance Co | 4,462 | $198.0K | 0.00% | 00.0% | Unchanged |
| Zebra Capital Management LLC | 4,495 | $200.0K | 0.32% | −1,657−26.9% | Reduced |
| Commonwealth Equity Services, LLC | 4,636 | $206.0K | 0.00% | +472+11.3% | Added |
| Raymond James & Associates | 4,926 | $220.0K | 0.00% | −1,245−20.2% | Reduced |
| Saturna Capital CORP | 5,000 | $223.0K | 0.00% | 00.0% | Unchanged |
| Beacon Investment Advisory Services, Inc. | 5,000 | $223.0K | 0.01% | 00.0% | Unchanged |
| Walled Lake Planning & Wealth Management, LLC | 5,020 | $224.0K | 0.13% | 00.0% | Unchanged |
| CIBC Asset Management Inc | 5,069 | $226.0K | 0.00% | +186+3.8% | Added |
| Blair William & Co | 5,100 | $227.0K | 0.00% | 00.0% | Unchanged |
| Creative Planning | 5,208 | $232.0K | 0.00% | 00.0% | Unchanged |
| Wilbanks Smith & Thomas Asset Management LLC | 5,381 | $240.0K | 0.01% | 00.0% | Unchanged |
| Vident Investment Advisory, LLC | 5,432 | $242.0K | 0.01% | +5,432 | New |
| Engineers Gate Manager LP | 5,690 | $254.0K | 0.01% | +5,690 | New |
| Gsa Capital Partners LLP | 5,834 | $260.0K | 0.03% | −9,058−60.8% | Reduced |
| Winton Group Ltd | 6,272 | $280.0K | 0.02% | +6,272 | New |
| O'Shaughnessy Asset Management, LLC | 6,687 | $298.0K | 0.01% | −19−0.3% | Reduced |
| Weiss Asset Management LP | 7,020 | $313.0K | 0.01% | +7,020 | New |
| Ameritas Investment Partners, Inc. | 7,134 | $318.0K | 0.01% | 00.0% | Unchanged |
| D. E. Shaw & Co., Inc. | 7,236 | $323.0K | 0.00% | −38,177−84.1% | Reduced |
| Mackenzie Financial Corp | 7,331 | $327.0K | 0.00% | −143−1.9% | Reduced |
| Tower Research Capital LLC (TRC) | 7,339 | $328.0K | 0.01% | +1,924+35.5% | Added |
| Algert Global LLC | 7,369 | $329.0K | 0.04% | 00.0% | Unchanged |
| Illinois Municipal Retirement Fund | 7,510 | $335.0K | 0.01% | 00.0% | Unchanged |
| Cubist Systematic Strategies, LLC | 7,866 | $351.0K | 0.00% | −1,740−18.1% | Reduced |
| Franklin Resources Inc | 8,246 | $368.0K | 0.00% | +8,246 | New |
| GAM Holding AG | 8,403 | $375.0K | 0.02% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 8,576 | $382.0K | 0.00% | −105,095−92.5% | Reduced |
| Brown Brothers Harriman & Co | 9,024 | $402.0K | 0.00% | +6,524+261.0% | Added |
| Royal Bank of Canada | 9,243 | $412.0K | 0.00% | +5,175+127.2% | Added |
| Simplex Trading, LLC | 9,376 | $418.0K | 0.01% | +9,376 | New |
| Brandywine Managers, LLC | 9,601 | $428.0K | 0.48% | +1,050+12.3% | Added |
| Prelude Capital Management, LLC | 9,610 | $429.0K | 0.02% | +3,598+59.8% | Added |
| Dana Investment Advisors, Inc. | 9,638 | $430.0K | 0.02% | +326+3.5% | Added |
| AlphaCrest Capital Management LLC | 9,811 | $438.0K | 0.02% | +3,411+53.3% | Added |
| Jump Financial, LLC | 10,203 | $455.0K | 0.03% | +10,203 | New |
| Nomura Asset Management Co Ltd | 10,402 | $463.9K | 0.00% | +10,402 | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 10,944 | $488.0K | 0.00% | +2,118+24.0% | Added |
| SEI Investments Co | 11,352 | $498.0K | 0.00% | −433−3.7% | Reduced |
| Utah Retirement Systems | 11,600 | $517.0K | 0.01% | 00.0% | Unchanged |
| Acadian Asset Management LLC | 11,805 | $526.0K | 0.00% | +957+8.8% | Added |
| Victory Capital Management Inc | 12,081 | $539.0K | 0.00% | −9,627−44.3% | Reduced |
| Dynamic Technology Lab Private Ltd | 12,160 | $542.0K | 0.06% | +12,160 | New |
| Public Employees Retirement Association of Colorado | 12,238 | $546.0K | 0.00% | 00.0% | Unchanged |
| Arthur M. Cohen & Associates, LLC | 12,416 | $554.0K | 0.10% | +4,869+64.5% | Added |
| Balyasny Asset Management LLC | 12,874 | $574.0K | 0.00% | +6,510+102.3% | Added |
| Stifel Financial Corp | 13,655 | $609.0K | 0.00% | −1,012−6.9% | Reduced |
| Capital Fund Management S.A. | 13,803 | $615.6K | 0.02% | −3,202−18.8% | Reduced |
| Voloridge Investment Management, LLC | 13,941 | $622.0K | 0.00% | −4,075−22.6% | Reduced |
| Group One Trading, L.P. | 14,345 | $640.0K | 0.01% | +14,345 | New |
| First Trust Advisors LP | 15,147 | $676.0K | 0.00% | −65,306−81.2% | Reduced |
| Teacher Retirement System of Texas | 15,569 | $694.0K | 0.00% | +2,996+23.8% | Added |
| Profund Advisors LLC | 15,840 | $706.0K | 0.02% | −1,813−10.3% | Reduced |
| Amalgamated Bank | 16,012 | $714.0K | 0.01% | −172−1.1% | Reduced |
| Rockefeller Capital Management L.P. | 16,458 | $733.0K | 0.00% | +1,659+11.2% | Added |
| Bartlett & Co. Wealth Management LLC | 16,943 | $755.7K | 0.01% | +15,443+1,029.5% | Added |
| Bartlett & Co. LLC | 16,943 | $756.0K | 0.01% | +15,443+1,029.5% | Added |
| Mercer Global Advisors Inc | 17,352 | $774.0K | 0.00% | −2,181−11.2% | Reduced |
| Handelsbanken Fonder AB | 18,000 | $803.0K | 0.00% | 00.0% | Unchanged |