Denali Therapeutics Inc.
DNLI- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.
13F holders, Q3 2021
Institutional positions in Denali Therapeutics Inc. as of Sep 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 214
- +6 vs. Q2 2021
- Shares held
- 84.8M
- +4.69M (+5.8%) vs. Q2 2021
- Total value
- $4.28B
- −$2.00B (−31.9%) vs. Q2 2021
- New holders
- 37
- 81 more added
- Sold out
- 31
- 65 more reduced
2 institutions that held it in Q2 2021 haven't filed for Q3 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 294 | $4.00B |
| Q1 2026 | 269 | $2.82B |
| Q4 2025 | 250 | $2.50B |
| Q3 2025 | 240 | $1.97B |
| Q2 2025 | 231 | $1.93B |
| Q1 2025 | 222 | $1.85B |
| Q4 2024 | 224 | $2.61B |
| Q3 2024 | 217 | $3.69B |
| Q2 2024 | 203 | $2.88B |
| Q1 2024 | 211 | $2.51B |
| Q4 2023 | 209 | $2.47B |
| Q3 2023 | 195 | $2.24B |
| Q2 2023 | 203 | $3.18B |
| Q1 2023 | 202 | $2.49B |
| Q4 2022 | 199 | $2.94B |
| Q3 2022 | 200 | $2.84B |
| Q2 2022 | 188 | $2.73B |
| Q1 2022 | 190 | $2.79B |
| Q4 2021 | 213 | $3.80B |
| Q3 2021 | 214 | $4.28B |
| Q2 2021 | 210 | $6.32B |
| Q1 2021 | 218 | $4.60B |
Institutions, Q3 2021
Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q2 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Baillie Gifford & Co | 15,009,816 | $757.2M | 0.40% | −137,797−0.9% | Reduced |
| Vanguard Group Inc | 8,168,483 | $412.1M | 0.01% | +524,353+6.9% | Added |
| Crestline Management, LP | 7,705,039 | $388.7M | 36.97% | −430,442−5.3% | Reduced |
| BlackRock Inc. | 7,560,837 | $381.4M | 0.01% | +524,796+7.5% | Added |
| Temasek Holdings (Private) Ltd | 5,369,487 | $270.9M | 0.95% | +959,030+21.7% | Added |
| Price T Rowe Associates Inc | 4,757,965 | $240.0M | 0.02% | −145,487−3.0% | Reduced |
| Gilder Gagnon Howe & Co LLC | 2,802,994 | $141.4M | 0.73% | −32,739−1.2% | Reduced |
| State Street Corp | 2,798,134 | $141.2M | 0.01% | +477,674+20.6% | Added |
| Flagship Pioneering Inc. | 2,730,263 | $137.7M | 1.44% | 00.0% | Unchanged |
| FMR LLC | 2,675,749 | $135.0M | 0.01% | +6,666+0.2% | Added |
| Credit Suisse AG | 1,982,473 | $100.0M | 0.08% | +15,965+0.8% | Added |
| Casdin Capital, LLC | 1,700,000 | $85.8M | 2.14% | +90,000+5.6% | Added |
| Geode Capital Management, LLC | 1,607,394 | $81.1M | 0.01% | +90,373+6.0% | Added |
| Bamco Inc | 1,127,919 | $56.9M | 0.13% | −127,305−10.1% | Reduced |
| Goldman Sachs Group Inc | 1,056,558 | $53.3M | 0.01% | +468,740+79.7% | Added |
| Pathway Capital Management, LP | 1,012,240 | $51.1M | 24.47% | +1,012,240 | New |
| Northern Trust Corp | 951,725 | $48.0M | 0.01% | −27,333−2.8% | Reduced |
| Pictet Asset Management SA | 868,503 | $43.8M | 0.05% | +868,503 | New |
| Norges Bank | 853,356 | $43.1M | 0.01% | +111,376+15.0% | Added |
| Charles Schwab Investment Management Inc | 703,752 | $35.5M | 0.01% | +63,518+9.9% | Added |
| Dimensional Fund Advisors LP | 634,735 | $32.0M | 0.01% | +309,387+95.1% | Added |
| Artisan Partners Limited Partnership | 550,987 | $27.8M | 0.03% | −15,858−2.8% | Reduced |
| Marshall Wace, LLP | 531,358 | $26.8M | 0.13% | −114,641−17.7% | Reduced |
| Artal Group S.A. | 500,000 | $25.2M | 0.62% | 00.0% | Unchanged |
| UBS Asset Management Americas Inc | 434,734 | $21.9M | 0.01% | +4,863+1.1% | Added |
| Two Sigma Advisers, LP | 421,100 | $21.2M | 0.06% | −43,000−9.3% | Reduced |
| Hamilton Lane Advisors LLC | 396,944 | $20.0M | 3.36% | +396,944 | New |
| Morgan Stanley | 383,993 | $19.4M | 0.00% | −47,039−10.9% | Reduced |
| Nuveen Asset Management, LLC | 365,078 | $19.3M | 0.01% | −18,982−4.9% | Reduced |
| Bank of New York Mellon Corp | 376,719 | $19.0M | 0.00% | +29,350+8.4% | Added |
| American Century Companies Inc | 348,987 | $17.6M | 0.01% | +56,140+19.2% | Added |
| Federated Hermes, Inc. | 339,160 | $17.1M | 0.03% | +200,528+144.6% | Added |
| Mitsubishi UFJ Trust & Banking Corp | 338,730 | $17.1M | 0.04% | −6,570−1.9% | Reduced |
| Principal Financial Group Inc | 303,827 | $15.3M | 0.01% | −25,517−7.7% | Reduced |
| Natixis | 279,254 | $14.1M | 0.05% | +69,556+33.2% | Added |
| Eagle Asset Management Inc | 242,545 | $12.2M | 0.06% | −48,558−16.7% | Reduced |
| Marshall Wace North America L.P. | 231,977 | $11.7M | 0.05% | +219,062+1,696.2% | Added |
| Jennison Associates LLC | 228,422 | $11.5M | 0.01% | −146,090−39.0% | Reduced |
| Tekla Capital Management LLC | 222,420 | $11.2M | 0.36% | +72,334+48.2% | Added |
| AXA S.A. | 201,580 | $10.2M | 0.03% | +18,880+10.3% | Added |
| California Public Employees Retirement System | 201,374 | $10.2M | 0.01% | +2,713+1.4% | Added |
| Prudential Financial Inc | 187,462 | $9.46M | 0.01% | −32,552−14.8% | Reduced |
| Wasatch Advisors Inc | 174,528 | $8.80M | 0.04% | −362,718−67.5% | Reduced |
| Swiss National Bank | 174,100 | $8.78M | 0.01% | +2,300+1.3% | Added |
| Teachers Retirement System of the State of Kentucky | 171,496 | $8.65M | 0.08% | −3,300−1.9% | Reduced |
| Wells Fargo & Company | 164,745 | $8.31M | 0.00% | +16,972+11.5% | Added |
| New York State Common Retirement Fund | 156,893 | $7.92M | 0.01% | −23,368−13.0% | Reduced |
| Alliancebernstein L.P. | 154,660 | $7.80M | 0.00% | −700−0.5% | Reduced |
| Skandinaviska Enskilda Banken AB (publ) | 132,054 | $6.66M | 0.04% | +102,269+343.4% | Added |
| Sectoral Asset Management Inc | 127,500 | $6.43M | 0.53% | +62,500+96.2% | Added |
| TD Asset Management Inc | 126,837 | $6.40M | 0.01% | 00.0% | Unchanged |
| State of Wisconsin Investment Board | 124,000 | $6.26M | 0.01% | +1,300+1.1% | Added |
| Deutsche Bank AG | 116,016 | $5.85M | 0.00% | −1,022−0.9% | Reduced |
| California State Teachers Retirement System | 113,735 | $5.74M | 0.01% | −11,644−9.3% | Reduced |
| Two Sigma Investments, LP | 113,671 | $5.74M | 0.02% | −105,744−48.2% | Reduced |
| Citigroup Inc | 109,025 | $5.50M | 0.01% | +43,778+67.1% | Added |
| Edmond de Rothschild Holding S.A. | 100,000 | $5.04M | 0.12% | +22,800+29.5% | Added |
| JPMorgan Chase & Co | 98,510 | $4.97M | 0.00% | +7,630+8.4% | Added |
| AIA Group Ltd | 98,441 | $4.97M | 0.28% | +16,550+20.2% | Added |
| Rhumbline Advisers | 97,405 | $4.91M | 0.01% | +2,550+2.7% | Added |
| Arrowstreet Capital, Limited Partnership | 96,868 | $4.89M | 0.01% | +96,868 | New |
| Renaissance Technologies LLC | 95,600 | $4.82M | 0.01% | +84,100+731.3% | Added |
| Baker Bros. Advisors LP | 88,738 | $4.48M | 0.02% | 00.0% | Unchanged |
| AQR Capital Management LLC | 82,049 | $4.14M | 0.01% | +2,765+3.5% | Added |
| First Trust Advisors LP | 80,453 | $4.06M | 0.00% | +19,135+31.2% | Added |
| Bank of America Corp | 77,846 | $3.92M | 0.00% | +14,094+22.1% | Added |
| Legal & General Group Plc | 77,528 | $3.91M | 0.00% | +15,284+24.6% | Added |
| Integral Health Asset Management, LLC | 75,000 | $3.78M | 1.09% | −6,000−7.4% | Reduced |
| Putnam Investments LLC | 71,701 | $3.62M | 0.01% | −170.0% | Reduced |
| ClariVest Asset Management LLC | 71,466 | $3.61M | 0.12% | −3,779−5.0% | Reduced |
| Barclays PLC | 70,965 | $3.58M | 0.00% | +47,204+198.7% | Added |
| Ensign Peak Advisors, Inc | 66,348 | $3.35M | 0.01% | +24,406+58.2% | Added |
| Castleark Management LLC | 66,145 | $3.34M | 0.13% | +37,105+127.8% | Added |
| CastleArk Alternatives, LLC | 66,145 | $3.34M | 0.13% | +66,145 | New |
| Russell Investments Group, Ltd. | 65,351 | $3.28M | 0.01% | +1,594+2.5% | Added |
| UBS Group AG | 64,480 | $3.25M | 0.00% | +62,043+2,545.9% | Added |
| Candriam Luxembourg S.C.A. | 63,781 | $3.22M | 0.02% | 00.0% | Unchanged |
| Citadel Advisors LLC | 63,011 | $3.18M | 0.00% | +63,011 | New |
| Rafferty Asset Management, LLC | 60,361 | $3.04M | 0.02% | +25,581+73.6% | Added |
| Tygh Capital Management, Inc. | 54,335 | $2.74M | 0.37% | +54,335 | New |
| State of New Jersey Common Pension Fund D | 54,308 | $2.74M | 0.01% | +3,448+6.8% | Added |
| Soros Capital Management LLC | 54,000 | $2.72M | 0.55% | 00.0% | Unchanged |
| Polar Capital Holdings Plc | 53,835 | $2.72M | 0.01% | +5,037+10.3% | Added |
| Susquehanna International Group, LLP | 52,097 | $2.63M | 0.00% | +32,872+171.0% | Added |
| DekaBank Deutsche Girozentrale | 52,900 | $2.61M | 0.01% | 00.0% | Unchanged |
| Jupiter Asset Management Ltd | 50,023 | $2.52M | 0.03% | +50,023 | New |
| American International Group, Inc. | 49,797 | $2.51M | 0.01% | −1,183−2.3% | Reduced |
| Invesco Ltd. | 48,218 | $2.43M | 0.00% | −335,347−87.4% | Reduced |
| Manufacturers Life Insurance Company, The | 46,935 | $2.37M | 0.00% | −4,398−8.6% | Reduced |
| D. E. Shaw & Co., Inc. | 45,413 | $2.29M | 0.00% | −38,172−45.7% | Reduced |
| University of Texas/Texas Am Investment Managment Co | 41,918 | $2.12M | 1.21% | +41,918 | New |
| Macquarie Group Ltd | 41,910 | $2.11M | 0.00% | 00.0% | Unchanged |
| Millennium Management LLC | 41,842 | $2.11M | 0.00% | +22,399+115.2% | Added |
| Los Angeles Capital Management LLC | 41,522 | $2.10M | 0.01% | +8,090+24.2% | Added |
| ProShare Advisors LLC | 39,837 | $2.01M | 0.01% | −5,525−12.2% | Reduced |
| Tao Capital Management LP | 38,949 | $1.97M | 0.52% | +38,949 | New |
| Voya Investment Management LLC | 35,591 | $1.80M | 0.00% | −174−0.5% | Reduced |
| Parametric Portfolio Associates LLC | 32,998 | $1.67M | 0.00% | −31,211−48.6% | Reduced |
| MetLife Investment Management | 32,389 | $1.63M | 0.01% | 00.0% | Unchanged |
| SG Americas Securities, LLC | 30,895 | $1.56M | 0.01% | +13,625+78.9% | Added |