Denali Therapeutics Inc.
DNLI- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.
13F holders, Q4 2022
Institutional positions in Denali Therapeutics Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 199
- −1 vs. Q3 2022
- Shares held
- 105.9M
- +13.5M (+14.6%) vs. Q3 2022
- Total value
- $2.94B
- +$108.6M (+3.8%) vs. Q3 2022
- New holders
- 27
- 86 more added
- Sold out
- 28
- 53 more reduced
Compare with Q3 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 294 | $4.00B |
| Q1 2026 | 269 | $2.82B |
| Q4 2025 | 250 | $2.50B |
| Q3 2025 | 240 | $1.97B |
| Q2 2025 | 231 | $1.93B |
| Q1 2025 | 222 | $1.85B |
| Q4 2024 | 224 | $2.61B |
| Q3 2024 | 217 | $3.69B |
| Q2 2024 | 203 | $2.88B |
| Q1 2024 | 211 | $2.51B |
| Q4 2023 | 209 | $2.47B |
| Q3 2023 | 195 | $2.24B |
| Q2 2023 | 203 | $3.18B |
| Q1 2023 | 202 | $2.49B |
| Q4 2022 | 199 | $2.94B |
| Q3 2022 | 200 | $2.84B |
| Q2 2022 | 188 | $2.73B |
| Q1 2022 | 190 | $2.79B |
| Q4 2021 | 213 | $3.80B |
| Q3 2021 | 214 | $4.28B |
| Q2 2021 | 210 | $6.32B |
| Q1 2021 | 218 | $4.60B |
Institutions, Q4 2022
Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q3 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Baillie Gifford & Co | 15,119,474 | $420.5M | 0.44% | +404,423+2.7% | Added |
| Vanguard Group Inc | 9,947,098 | $276.6M | 0.01% | +1,545,067+18.4% | Added |
| BlackRock Inc. | 9,322,014 | $259.2M | 0.01% | +723,802+8.4% | Added |
| Crestline Management, LP | 6,860,732 | $190.8M | 27.96% | −300,000−4.2% | Reduced |
| Temasek Holdings (Private) Ltd | 6,516,041 | $181.2M | 1.06% | +940,000+16.9% | Added |
| Wellington Management Group LLP | 5,121,730 | $142.4M | 0.03% | +5,100,036+23,509.0% | Added |
| State Street Corp | 4,845,810 | $134.8M | 0.01% | +653,582+15.6% | Added |
| ARCH Venture Management, LLC | 3,668,749 | $102.0M | 26.13% | 00.0% | Unchanged |
| Price T Rowe Associates Inc | 3,648,888 | $101.5M | 0.02% | +170,520+4.9% | Added |
| Flagship Pioneering Inc. | 2,619,968 | $72.9M | 2.33% | 00.0% | Unchanged |
| Capital Research Global Investors | 2,260,642 | $62.9M | 0.02% | +2,172,875+2,475.7% | Added |
| FMR LLC | 2,213,794 | $61.6M | 0.01% | −238,662−9.7% | Reduced |
| Geode Capital Management, LLC | 2,049,957 | $57.0M | 0.01% | +273,793+15.4% | Added |
| Bank of New York Mellon Corp | 2,005,920 | $55.8M | 0.01% | +110,628+5.8% | Added |
| Gilder Gagnon Howe & Co LLC | 1,767,142 | $49.1M | 0.92% | −96,135−5.2% | Reduced |
| Credit Suisse AG | 1,533,383 | $42.6M | 0.05% | −78,046−4.8% | Reduced |
| Casdin Capital, LLC | 1,300,000 | $36.2M | 2.82% | +305,000+30.7% | Added |
| Pictet Asset Management SA | 1,171,356 | $32.6M | 0.05% | +168,171+16.8% | Added |
| Baker Bros. Advisors LP | 1,088,738 | $30.3M | 0.18% | +500,000+84.9% | Added |
| Norges Bank | 1,024,206 | $28.5M | 0.01% | +80,802+8.6% | Added |
| Yiheng Capital Management, L.P. | 1,014,684 | $28.2M | 2.19% | 00.0% | Unchanged |
| Northern Trust Corp | 984,191 | $27.4M | 0.01% | +94,223+10.6% | Added |
| Marshall Wace, LLP | 960,639 | $26.7M | 0.07% | +284,769+42.1% | Added |
| Charles Schwab Investment Management Inc | 836,673 | $23.3M | 0.01% | +105,793+14.5% | Added |
| Artal Group S.A. | 800,000 | $22.2M | 1.28% | +200,000+33.3% | Added |
| Deerfield Management Company, L.P. (Series C) | 800,000 | $22.2M | 0.46% | +800,000 | New |
| Federated Hermes, Inc. | 775,000 | $21.6M | 0.06% | +118,407+18.0% | Added |
| Goldman Sachs Group Inc | 771,452 | $21.5M | 0.01% | +43,180+5.9% | Added |
| T. Rowe Price Investment Management, Inc. | 633,358 | $17.6M | 0.01% | +211,001+50.0% | Added |
| Cercano Management LLC | 625,000 | $17.4M | 0.71% | +625,000 | New |
| Barclays PLC | 585,965 | $16.3M | 0.01% | +260,498+80.0% | Added |
| Dimensional Fund Advisors LP | 558,258 | $15.5M | 0.01% | −51,581−8.5% | Reduced |
| UBS Asset Management Americas Inc | 543,923 | $15.1M | 0.01% | +13,719+2.6% | Added |
| Principal Financial Group Inc | 526,459 | $14.6M | 0.01% | −19,412−3.6% | Reduced |
| American Century Companies Inc | 472,288 | $13.1M | 0.01% | −860.0% | Reduced |
| Wasatch Advisors Inc | 450,950 | $12.5M | 0.08% | +91,477+25.4% | Added |
| Artisan Partners Limited Partnership | 435,673 | $12.1M | 0.02% | −7,428−1.7% | Reduced |
| Morgan Stanley | 432,486 | $12.0M | 0.00% | −248,846−36.5% | Reduced |
| Nuveen Asset Management, LLC | 375,747 | $10.4M | 0.00% | +24,288+6.9% | Added |
| Candriam Luxembourg S.C.A. | 357,878 | $9.95M | 0.07% | 00.0% | Unchanged |
| Bank of America Corp | 334,772 | $9.31M | 0.00% | +114,555+52.0% | Added |
| Eagle Asset Management Inc | 329,084 | $9.09M | 0.06% | +73,624+28.8% | Added |
| Skandinaviska Enskilda Banken AB (publ) | 309,092 | $8.60M | 0.06% | +17,784+6.1% | Added |
| Mitsubishi UFJ Trust & Banking Corp | 301,870 | $8.40M | 0.02% | −5,590−1.8% | Reduced |
| Millennium Management LLC | 297,093 | $8.26M | 0.01% | −199,091−40.1% | Reduced |
| AXA S.A. | 289,920 | $8.06M | 0.03% | +41,148+16.5% | Added |
| Rafferty Asset Management, LLC | 283,742 | $7.89M | 0.07% | +76,374+36.8% | Added |
| Tekla Capital Management LLC | 272,520 | $7.58M | 0.29% | +50,100+22.5% | Added |
| Bamco Inc | 264,256 | $7.35M | 0.02% | −10,606−3.9% | Reduced |
| Clarius Group, LLC | 260,604 | $7.25M | 0.65% | 00.0% | Unchanged |
| Renaissance Technologies LLC | 249,600 | $6.94M | 0.01% | −142,600−36.4% | Reduced |
| Sectoral Asset Management Inc | 243,850 | $6.78M | 1.31% | +500+0.2% | Added |
| Swiss National Bank | 208,500 | $5.80M | 0.00% | +4,400+2.2% | Added |
| Teachers Retirement System of the State of Kentucky | 206,500 | $5.74M | 0.06% | +29,304+16.5% | Added |
| California Public Employees Retirement System | 193,561 | $5.38M | 0.00% | −6,294−3.1% | Reduced |
| JPMorgan Chase & Co | 183,976 | $5.12M | 0.00% | +75,622+69.8% | Added |
| Voya Investment Management LLC | 169,874 | $4.72M | 0.01% | +3,938+2.4% | Added |
| Alliancebernstein L.P. | 154,960 | $4.31M | 0.00% | 00.0% | Unchanged |
| Two Sigma Advisers, LP | 151,800 | $4.22M | 0.01% | −32,000−17.4% | Reduced |
| New York State Common Retirement Fund | 150,954 | $4.20M | 0.01% | +6,049+4.2% | Added |
| Rhumbline Advisers | 142,932 | $3.98M | 0.01% | +14,999+11.7% | Added |
| Man Group plc | 142,929 | $3.97M | 0.01% | +108,508+315.2% | Added |
| Ensign Peak Advisors, Inc | 142,547 | $3.96M | 0.01% | +19,900+16.2% | Added |
| D. E. Shaw & Co., Inc. | 134,427 | $3.74M | 0.01% | +134,427 | New |
| Citigroup Inc | 128,120 | $3.56M | 0.01% | −64,522−33.5% | Reduced |
| UBS Group AG | 120,181 | $3.34M | 0.00% | +77,727+183.1% | Added |
| California State Teachers Retirement System | 118,581 | $3.30M | 0.01% | +5,618+5.0% | Added |
| Manufacturers Life Insurance Company, The | 112,059 | $3.14M | 0.00% | +1,802+1.6% | Added |
| Deutsche Bank AG | 110,730 | $3.08M | 0.00% | +9,880+9.8% | Added |
| Edmond de Rothschild Holding S.A. | 99,880 | $2.78M | 0.07% | 00.0% | Unchanged |
| Russell Investments Group, Ltd. | 99,373 | $2.76M | 0.01% | −7,488−7.0% | Reduced |
| TD Asset Management Inc | 99,209 | $2.76M | 0.00% | +5,086+5.4% | Added |
| Legal & General Group Plc | 95,015 | $2.64M | 0.00% | +8,998+10.5% | Added |
| Northwest & Ethical Investments L.P. | 94,863 | $2.64M | 0.09% | +14,983+18.8% | Added |
| Alps Advisors Inc | 92,029 | $2.56M | 0.02% | +24,706+36.7% | Added |
| Susquehanna Fundamental Investments, LLC | 91,249 | $2.54M | 0.04% | +91,249 | New |
| Invesco Ltd. | 88,739 | $2.47M | 0.00% | +10,844+13.9% | Added |
| State of Wisconsin Investment Board | 86,566 | $2.41M | 0.01% | −990−1.1% | Reduced |
| State of New Jersey Common Pension Fund D | 78,253 | $2.18M | 0.01% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 74,435 | $2.07M | 0.01% | −186,735−71.5% | Reduced |
| Guggenheim Capital LLC | 64,691 | $1.80M | 0.02% | +14,256+28.3% | Added |
| Wells Fargo & Company | 64,689 | $1.80M | 0.00% | −198−0.3% | Reduced |
| Point72 Asset Management, L.P. | 64,400 | $1.79M | 0.01% | −568,600−89.8% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 61,096 | $1.70M | 0.01% | −51,436−45.7% | Reduced |
| DekaBank Deutsche Girozentrale | 59,800 | $1.67M | 0.00% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 57,688 | $1.60M | 0.00% | −50,881−46.9% | Reduced |
| MetLife Investment Management | 57,027 | $1.59M | 0.01% | +4,600+8.8% | Added |
| Platinum Investment Management Ltd | 55,341 | $1.54M | 0.06% | +4,370+8.6% | Added |
| Mirae Asset Global Investments Co., Ltd. | 54,607 | $1.52M | 0.00% | +5,709+11.7% | Added |
| American International Group, Inc. | 51,484 | $1.43M | 0.01% | +4,707+10.1% | Added |
| Tudor Investment Corp Et Al | 49,931 | $1.39M | 0.03% | +49,931 | New |
| ClariVest Asset Management LLC | 49,228 | $1.37M | 0.07% | −152−0.3% | Reduced |
| Envestnet Asset Management Inc | 40,917 | $1.14M | 0.00% | −599−1.4% | Reduced |
| TCW Group Inc | 39,031 | $1.09M | 0.02% | +39,031 | New |
| International Biotechnology Trust PLC | 38,000 | $1.06M | 0.33% | 00.0% | Unchanged |
| Pier 88 Investment Partners LLC | 35,240 | $980.0K | 0.24% | +23,150+191.5% | Added |
| Citadel Advisors LLC | 34,613 | $962.6K | 0.00% | −28,924−45.5% | Reduced |
| STRS Ohio | 33,700 | $937.0K | 0.00% | 00.0% | Unchanged |
| State Board of Administration of Florida Retirement System | 32,288 | $897.9K | 0.00% | 00.0% | Unchanged |
| Bellevue Group AG | 31,000 | $862.1K | 0.01% | 00.0% | Unchanged |