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Denali Therapeutics Inc.

DNLI
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001714899

In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.

13F holders, Q4 2022

Institutional positions in Denali Therapeutics Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
199
−1 vs. Q3 2022
Shares held
105.9M
+13.5M (+14.6%) vs. Q3 2022
Total value
$2.94B
+$108.6M (+3.8%) vs. Q3 2022
New holders
27
86 more added
Sold out
28
53 more reduced

Compare with Q3 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2022: 199 institutions
Q1 2021: 218 institutionsQ2 2021: 210 institutionsQ3 2021: 214 institutionsQ4 2021: 213 institutionsQ1 2022: 190 institutionsQ2 2022: 188 institutionsQ3 2022: 200 institutionsQ4 2022: 199 institutionsQ1 2023: 202 institutionsQ2 2023: 203 institutionsQ3 2023: 195 institutionsQ4 2023: 209 institutionsQ1 2024: 211 institutionsQ2 2024: 203 institutionsQ3 2024: 217 institutionsQ4 2024: 224 institutionsQ1 2025: 222 institutionsQ2 2025: 231 institutionsQ3 2025: 240 institutionsQ4 2025: 250 institutionsQ1 2026: 269 institutionsQ2 2026: 294 institutions
Value heldQ4 2022: $2.94B
Q1 2021: $4.60BQ2 2021: $6.32BQ3 2021: $4.28BQ4 2021: $3.80BQ1 2022: $2.79BQ2 2022: $2.73BQ3 2022: $2.84BQ4 2022: $2.94BQ1 2023: $2.49BQ2 2023: $3.18BQ3 2023: $2.24BQ4 2023: $2.47BQ1 2024: $2.51BQ2 2024: $2.88BQ3 2024: $3.69BQ4 2024: $2.61BQ1 2025: $1.85BQ2 2025: $1.93BQ3 2025: $1.97BQ4 2025: $2.50BQ1 2026: $2.82BQ2 2026: $4.00B
Institutions holding DNLI and their total value by quarter
QuarterHoldersValue
Q2 2026294$4.00B
Q1 2026269$2.82B
Q4 2025250$2.50B
Q3 2025240$1.97B
Q2 2025231$1.93B
Q1 2025222$1.85B
Q4 2024224$2.61B
Q3 2024217$3.69B
Q2 2024203$2.88B
Q1 2024211$2.51B
Q4 2023209$2.47B
Q3 2023195$2.24B
Q2 2023203$3.18B
Q1 2023202$2.49B
Q4 2022199$2.94B
Q3 2022200$2.84B
Q2 2022188$2.73B
Q1 2022190$2.79B
Q4 2021213$3.80B
Q3 2021214$4.28B
Q2 2021210$6.32B
Q1 2021218$4.60B

Institutions, Q4 2022

Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q3 2022.

Institutions holding DNLI in Q4 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Ronald Blue Trust, Inc.8$00.00%+2+33.3%Added
VitalStone Financial, LLC15$00.00%+15New
Global Retirement Partners, LLC3$830.00%00.0%Unchanged
Allworth Financial LP8$2220.00%00.0%Unchanged
Institutional & Family Asset Management, LLC11$3060.00%+5+83.3%Added
Sofos Investments, Inc.28$3590.00%+28New
Baker Avenue Asset Management, LP22$6120.00%+22New
IFP Advisors, Inc15$1.00K0.00%+15New
Quadrant Capital Group LLC40$1.11K0.00%−10−20.0%Reduced
Leonteq Securities AG50$1.39K0.00%−40−44.4%Reduced
Bell Investment Advisors, Inc64$1.78K0.00%00.0%Unchanged
CWM, LLC60$2.00K0.00%−20−25.0%Reduced
Signaturefd, LLC95$2.64K0.00%+55+137.5%Added
Your Advocates Ltd., LLP100$2.78K0.00%00.0%Unchanged
Ellevest, Inc.119$3.31K0.00%+119New
Activest Wealth Management131$3.64K0.00%00.0%Unchanged
HealthInvest Partners AB158$4.39K0.01%+158New
First Horizon Advisors, Inc.215$5.98K0.00%00.0%Unchanged
Covestor Ltd202$6.00K0.00%−1−0.5%Reduced
Comerica Securities,inc.225$6.26K0.00%+225New
City State Bank250$7.00K0.00%00.0%Unchanged
Itau Unibanco Holding S.A.268$7.45K0.00%−1,130−80.8%Reduced
Advisory Services Network, LLC300$8.34K0.00%+300New
Umb Bank N A306$9.00K0.00%00.0%Unchanged
Huntington National Bank341$9.48K0.00%−6−1.7%Reduced
Lindbrook Capital, LLC355$9.87K0.00%+78+28.2%Added
Belpointe Asset Management LLC374$10.4K0.00%+374New
US Bancorp457$12.7K0.00%−46−9.1%Reduced
Daiwa Securities Group Inc.546$15.0K0.00%+88+19.2%Added
Assetmark, Inc574$16.0K0.00%+136+31.1%Added
High Net Worth Advisory Group LLC1,000$27.8K0.01%00.0%Unchanged
Balyasny Asset Management LLC1,313$36.5K0.00%+1,313New
Simplex Trading, LLC1,382$38.0K0.00%−2,068−59.9%Reduced
China Universal Asset Management Co., Ltd.1,380$38.4K0.02%+225+19.5%Added
Tower Research Capital LLC (TRC)1,554$44.0K0.00%−12,662−89.1%Reduced
The PNC Financial Services Group, Inc.1,669$46.4K0.00%+768+85.2%Added
Advisor Group Holdings, Inc.2,220$61.6K0.00%−610−21.6%Reduced
Cutler Group LP2,250$62.0K0.01%+1,450+181.3%Added
Sandia Investment Management LP2,500$69.5K0.01%+2,500New
Exchange Traded Concepts, LLC2,584$71.9K0.00%+408+18.8%Added
Allspring Global Investments Holdings, LLC3,242$90.2K0.00%−71−2.1%Reduced
Point72 Middle East FZE3,593$99.9K0.01%+3,593New
Ally Bridge Group (NY) LLC4,479$124.6K0.12%+4,479New
SG Americas Securities, LLC4,546$126.0K0.00%−8,305−64.6%Reduced
Virtus ETF Advisers LLC4,552$126.6K0.07%−323−6.6%Reduced
Great West Life Assurance Co4,642$130.0K0.00%00.0%Unchanged
Cubist Systematic Strategies, LLC4,840$134.6K0.00%−33,501−87.4%Reduced
Lazard Asset Management LLC5,353$148.0K0.00%00.0%Unchanged
Public Employees Retirement System of Ohio6,251$174.0K0.00%+6,251New
Metropolitan Life Insurance Co6,725$187.0K0.01%+780+13.1%Added
Prelude Capital Management, LLC7,343$204.2K0.01%+7,343New
Creative Planning7,469$207.7K0.00%+181+2.5%Added
Mackenzie Financial Corp7,959$221.3K0.00%+1,438+22.1%Added
Prudential Financial Inc9,186$255.5K0.00%+897+10.8%Added
HSBC Holdings PLC9,349$255.6K0.00%+1,675+21.8%Added
Ameritas Investment Partners, Inc.8,709$258.7K0.01%+1,240+16.6%Added
Brandywine Managers, LLC9,601$267.0K0.93%00.0%Unchanged
Rockefeller Capital Management L.P.9,858$273.0K0.00%−1,976−16.7%Reduced
Raymond James & Associates9,917$275.8K0.00%+9,917New
Aigen Investment Management, LP10,751$299.0K0.04%+10,751New
Allianz Asset Management GmbH11,300$314.3K0.00%00.0%Unchanged
Public Employees Retirement Association of Colorado12,238$340.0K0.00%00.0%Unchanged
XTX Topco Ltd12,231$340.1K0.07%+208+1.7%Added
Two Sigma Securities, LLC12,306$342.2K0.05%+12,306New
Zurcher Kantonalbank (Zurich Cantonalbank)12,318$342.6K0.00%+810+7.0%Added
Virginia Retirement Systems Et Al12,700$353.2K0.00%−300−2.3%Reduced
SEI Investments Co12,701$353.2K0.00%−3,317−20.7%Reduced
Gotham Asset Management, LLC13,029$362.3K0.01%−1,578−10.8%Reduced
Victory Capital Management Inc13,256$368.6K0.00%+1,631+14.0%Added
Stifel Financial Corp13,407$372.8K0.00%−141−1.0%Reduced
VELA Investment Management, LLC13,746$382.3K0.19%+4,905+55.5%Added
Handelsbanken Fonder AB14,100$392.0K0.00%+700+5.2%Added
E Fund Management Co., Ltd.14,861$413.0K0.03%+607+4.3%Added
Profund Advisors LLC14,867$413.5K0.03%+1,905+14.7%Added
Jane Street Group, LLC14,969$416.3K0.00%+14,969New
Bridgewater Associates, LP14,970$416.3K0.00%+14,970New
Arthur M. Cohen & Associates, LLC15,338$426.6K0.12%00.0%Unchanged
Janus Henderson Group PLC15,889$441.7K0.00%−10.0%Reduced
Nisa Investment Advisors, LLC17,918$498.0K0.00%00.0%Unchanged
Amalgamated Bank17,959$499.0K0.00%+2,017+12.7%Added
Linden Thomas Advisory Services, LLC18,264$507.9K0.14%+18,264New
Ironwood Investment Management LLC19,149$532.5K0.35%−759−3.8%Reduced
Royal Bank of Canada19,221$535.0K0.00%+15,206+378.7%Added
Bartlett & Co. Wealth Management LLC20,780$577.9K0.01%00.0%Unchanged
Bartlett & Co. LLC20,780$578.0K0.01%00.0%Unchanged
Los Angeles Capital Management LLC20,902$581.3K0.00%−21,839−51.1%Reduced
Voloridge Investment Management, LLC21,487$597.6K0.00%−20,869−49.3%Reduced
HighTower Advisors, LLC22,209$623.0K0.00%+3,386+18.0%Added
AIA Group Ltd22,762$633.0K0.04%−14,264−38.5%Reduced
Trexquant Investment LP22,855$635.6K0.02%−2,774−10.8%Reduced
Susquehanna International Group, LLP23,253$646.7K0.00%−73,374−75.9%Reduced
Arizona State Retirement System24,364$677.6K0.01%+976+4.2%Added
Dana Investment Advisors, Inc.25,116$698.5K0.04%+4,719+23.1%Added
Teacher Retirement System of Texas26,149$727.0K0.01%−2,072−7.3%Reduced
ProShare Advisors LLC26,908$748.3K0.00%+4,119+18.1%Added
Mercer Global Advisors Inc27,030$752.0K0.00%+821+3.1%Added
Erste Asset Management GmbH26,900$757.2K0.02%00.0%Unchanged
Concentric Wealth Management, LLC27,967$777.8K0.27%00.0%Unchanged
Algert Global LLC29,426$818.3K0.05%+21,792+285.5%Added
Bellevue Group AG31,000$862.1K0.01%00.0%Unchanged