Denali Therapeutics Inc.
DNLI- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.
13F holders, Q4 2023
Institutional positions in Denali Therapeutics Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 209
- +16 vs. Q3 2023
- Shares held
- 115.0M
- +6.57M (+6.1%) vs. Q3 2023
- Total value
- $2.47B
- +$224.9M (+10.0%) vs. Q3 2023
- New holders
- 37
- 71 more added
- Sold out
- 21
- 69 more reduced
2 institutions that held it in Q3 2023 haven't filed for Q4 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 294 | $4.00B |
| Q1 2026 | 269 | $2.82B |
| Q4 2025 | 250 | $2.50B |
| Q3 2025 | 240 | $1.97B |
| Q2 2025 | 231 | $1.93B |
| Q1 2025 | 222 | $1.85B |
| Q4 2024 | 224 | $2.61B |
| Q3 2024 | 217 | $3.69B |
| Q2 2024 | 203 | $2.88B |
| Q1 2024 | 211 | $2.51B |
| Q4 2023 | 209 | $2.47B |
| Q3 2023 | 195 | $2.24B |
| Q2 2023 | 203 | $3.18B |
| Q1 2023 | 202 | $2.49B |
| Q4 2022 | 199 | $2.94B |
| Q3 2022 | 200 | $2.84B |
| Q2 2022 | 188 | $2.73B |
| Q1 2022 | 190 | $2.79B |
| Q4 2021 | 213 | $3.80B |
| Q3 2021 | 214 | $4.28B |
| Q2 2021 | 210 | $6.32B |
| Q1 2021 | 218 | $4.60B |
Institutions, Q4 2023
Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q3 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Baillie Gifford & Co | 14,260,724 | $306.0M | 0.24% | −420,303−2.9% | Reduced |
| BlackRock Inc. | 11,543,446 | $247.7M | 0.01% | +658,150+6.0% | Added |
| Vanguard Group Inc | 10,834,483 | $232.5M | 0.01% | +236,702+2.2% | Added |
| Wellington Management Group LLP | 7,274,717 | $156.1M | 0.03% | −14,243−0.2% | Reduced |
| Temasek Holdings (Private) Ltd | 6,895,992 | $148.0M | 0.83% | 00.0% | Unchanged |
| Crestline Management, LP | 5,660,732 | $121.5M | 11.25% | −300,000−5.0% | Reduced |
| State Street Corp | 5,485,948 | $117.7M | 0.01% | +1,210,620+28.3% | Added |
| Takeda Pharmaceutical Co Ltd | 4,214,559 | $86.9M | 26.55% | +4,214,559 | New |
| Capital Research Global Investors | 2,909,528 | $62.4M | 0.02% | +29,205+1.0% | Added |
| Geode Capital Management, LLC | 2,659,296 | $57.1M | 0.01% | +127,461+5.0% | Added |
| Baker Bros. Advisors LP | 2,607,196 | $56.0M | 0.64% | +315,193+13.8% | Added |
| Price T Rowe Associates Inc | 2,574,321 | $55.2M | 0.01% | −317,629−11.0% | Reduced |
| Flagship Pioneering Inc. | 2,319,968 | $49.8M | 3.76% | −300,000−11.5% | Reduced |
| Bank of New York Mellon Corp | 1,870,627 | $40.1M | 0.01% | −93,061−4.7% | Reduced |
| Marshall Wace, LLP | 1,667,397 | $35.8M | 0.07% | +1,667,397 | New |
| Credit Suisse AG | 1,576,221 | $33.8M | 0.03% | +8,912+0.6% | Added |
| Federated Hermes, Inc. | 1,351,900 | $29.0M | 0.07% | 00.0% | Unchanged |
| Casdin Capital, LLC | 1,300,000 | $27.9M | 2.75% | 00.0% | Unchanged |
| Gilder Gagnon Howe & Co LLC | 1,219,392 | $26.2M | 0.36% | −26,807−2.2% | Reduced |
| Norges Bank | 1,152,646 | $24.7M | 0.00% | +348,754+43.4% | Added |
| Yiheng Capital Management, L.P. | 1,150,684 | $24.7M | 3.06% | 00.0% | Unchanged |
| Dimensional Fund Advisors LP | 1,119,628 | $24.0M | 0.01% | +146,394+15.0% | Added |
| Northern Trust Corp | 1,101,679 | $23.6M | 0.00% | −15,063−1.3% | Reduced |
| Principal Financial Group Inc | 1,073,704 | $23.0M | 0.01% | +393,626+57.9% | Added |
| Charles Schwab Investment Management Inc | 1,006,997 | $21.6M | 0.01% | +25,938+2.6% | Added |
| Morgan Stanley | 977,493 | $21.0M | 0.00% | −4,076−0.4% | Reduced |
| Artal Group S.A. | 802,899 | $17.2M | 0.59% | 00.0% | Unchanged |
| UBS Asset Management Americas Inc | 708,339 | $15.2M | 0.01% | +65,039+10.1% | Added |
| Point72 Asset Management, L.P. | 644,406 | $13.8M | 0.04% | +644,406 | New |
| FMR LLC | 641,653 | $13.8M | 0.00% | −416,844−39.4% | Reduced |
| Cercano Management LLC | 625,000 | $13.4M | 0.44% | 00.0% | Unchanged |
| T. Rowe Price Investment Management, Inc. | 498,969 | $10.7M | 0.01% | −148,044−22.9% | Reduced |
| American Century Companies Inc | 473,494 | $10.2M | 0.01% | −842−0.2% | Reduced |
| Braidwell LP | 461,769 | $9.91M | 0.36% | +461,769 | New |
| Bank of America Corp | 458,638 | $9.84M | 0.00% | +162,844+55.1% | Added |
| Polar Capital Holdings Plc | 452,669 | $9.71M | 0.07% | −554,417−55.1% | Reduced |
| Pictet Asset Management Holding SA | 439,218 | $9.43M | 0.01% | −150,281−25.5% | Reduced |
| Goldman Sachs Group Inc | 393,805 | $8.45M | 0.00% | −13,588−3.3% | Reduced |
| Artisan Partners Limited Partnership | 383,942 | $8.24M | 0.01% | −22,680−5.6% | Reduced |
| ARCH Venture Management, LLC | 381,249 | $8.18M | 5.00% | −312,500−45.0% | Reduced |
| Clarius Group, LLC | 378,262 | $8.12M | 0.67% | 00.0% | Unchanged |
| AXA S.A. | 360,595 | $7.74M | 0.02% | +6,066+1.7% | Added |
| Candriam Luxembourg S.C.A. | 357,878 | $7.68M | 0.05% | 00.0% | Unchanged |
| Ensign Peak Advisors, Inc | 348,497 | $7.48M | 0.01% | 00.0% | Unchanged |
| Skandinaviska Enskilda Banken AB (publ) | 348,203 | $7.47M | 0.04% | 00.0% | Unchanged |
| Standard Life Aberdeen plc | 324,829 | $6.97M | 0.02% | +324,829 | New |
| Barclays PLC | 324,019 | $6.95M | 0.00% | +157,512+94.6% | Added |
| Rafferty Asset Management, LLC | 321,973 | $6.91M | 0.03% | +92,660+40.4% | Added |
| Nuveen Asset Management, LLC | 319,437 | $6.86M | 0.00% | −44,228−12.2% | Reduced |
| Eagle Asset Management Inc | 315,520 | $6.77M | 0.04% | +26,387+9.1% | Added |
| Wasatch Advisors Inc | 312,301 | $6.70M | 0.04% | −9,166−2.9% | Reduced |
| UBS Group AG | 290,985 | $6.24M | 0.00% | +181,289+165.3% | Added |
| Voya Investment Management LLC | 284,104 | $6.10M | 0.01% | +19,488+7.4% | Added |
| Balyasny Asset Management LLC | 260,587 | $5.59M | 0.02% | +260,587 | New |
| Mitsubishi UFJ Trust & Banking Corp | 246,190 | $5.28M | 0.01% | −44,770−15.4% | Reduced |
| Swiss National Bank | 216,700 | $4.65M | 0.00% | −24,100−10.0% | Reduced |
| Teachers Retirement System of the State of Kentucky | 208,644 | $4.48M | 0.04% | −9,550−4.4% | Reduced |
| Woodline Partners LP | 197,584 | $4.24M | 0.05% | −653,905−76.8% | Reduced |
| BNP Paribas Arbitrage, SA | 191,643 | $4.11M | 0.01% | +28,817+17.7% | Added |
| JPMorgan Chase & Co | 183,316 | $3.93M | 0.00% | +15,352+9.1% | Added |
| California Public Employees Retirement System | 176,131 | $3.78M | 0.00% | 00.0% | Unchanged |
| Hudson Bay Capital Management LP | 175,000 | $3.76M | 0.03% | +175,000 | New |
| Pier Capital, LLC | 174,219 | $3.74M | 0.53% | +49,139+39.3% | Added |
| Qube Research & Technologies Ltd | 171,262 | $3.68M | 0.01% | +157,709+1,163.6% | Added |
| Rhumbline Advisers | 166,763 | $3.58M | 0.00% | −2,361−1.4% | Reduced |
| Edmond de Rothschild Holding S.A. | 165,680 | $3.56M | 0.06% | +65,800+65.9% | Added |
| Jefferies Financial Group Inc. | 165,327 | $3.55M | 0.06% | +152,527+1,191.6% | Added |
| Renaissance Technologies LLC | 161,946 | $3.48M | 0.01% | −305,905−65.4% | Reduced |
| Schroder Investment Management Group | 154,000 | $3.30M | 0.00% | +154,000 | New |
| Jane Street Group, LLC | 148,965 | $3.20M | 0.00% | +110,226+284.5% | Added |
| Neuberger Berman Group LLC | 144,461 | $3.10M | 0.00% | +144,461 | New |
| Citigroup Inc | 141,276 | $3.03M | 0.00% | +2,967+2.1% | Added |
| Alliancebernstein L.P. | 139,960 | $3.00M | 0.00% | +3,200+2.3% | Added |
| State of New Jersey Common Pension Fund D | 136,600 | $2.93M | 0.01% | +29,511+27.6% | Added |
| Soleus Capital Management, L.P. | 130,000 | $2.79M | 0.31% | +130,000 | New |
| New York State Common Retirement Fund | 123,974 | $2.66M | 0.00% | −5,879−4.5% | Reduced |
| California State Teachers Retirement System | 117,351 | $2.52M | 0.00% | −5,553−4.5% | Reduced |
| Deutsche Bank AG | 115,352 | $2.48M | 0.00% | −1,146−1.0% | Reduced |
| Russell Investments Group, Ltd. | 111,473 | $2.39M | 0.00% | −2,585−2.3% | Reduced |
| Legal & General Group Plc | 106,713 | $2.29M | 0.00% | +888+0.8% | Added |
| Manufacturers Life Insurance Company, The | 101,223 | $2.17M | 0.00% | −12,175−10.7% | Reduced |
| Alps Advisors Inc | 97,962 | $2.10M | 0.02% | −3,438−3.4% | Reduced |
| State of Wisconsin Investment Board | 91,521 | $1.96M | 0.01% | −6,335−6.5% | Reduced |
| TD Asset Management Inc | 91,044 | $1.95M | 0.00% | −43,956−32.6% | Reduced |
| Prudential Financial Inc | 81,244 | $1.74M | 0.00% | −72,584−47.2% | Reduced |
| Invesco Ltd. | 79,139 | $1.70M | 0.00% | −9,214−10.4% | Reduced |
| Knights of Columbus Asset Advisors LLC | 77,352 | $1.66M | 0.11% | +39,224+102.9% | Added |
| Mirae Asset Global Investments Co., Ltd. | 73,585 | $1.58M | 0.00% | +3,911+5.6% | Added |
| Seven Eight Capital, LP | 72,587 | $1.56M | 0.18% | +72,587 | New |
| Northwest & Ethical Investments L.P. | 71,284 | $1.53M | 0.05% | −3,484−4.7% | Reduced |
| Pathway Capital Management, LP | 69,450 | $1.49M | 1.67% | +69,450 | New |
| Citadel Advisors LLC | 68,110 | $1.46M | 0.00% | +6,205+10.0% | Added |
| AIA Group Ltd | 68,078 | $1.46M | 0.06% | −369−0.5% | Reduced |
| Wells Fargo & Company | 66,365 | $1.42M | 0.00% | −69,561−51.2% | Reduced |
| DekaBank Deutsche Girozentrale | 64,210 | $1.42M | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 66,059 | $1.42M | 0.01% | +48,099+267.8% | Added |
| Campbell & CO Investment Adviser LLC | 65,105 | $1.40M | 0.13% | +47,847+277.2% | Added |
| MetLife Investment Management | 62,264 | $1.34M | 0.01% | 00.0% | Unchanged |
| Susquehanna International Group, LLP | 60,914 | $1.31M | 0.00% | −32,889−35.1% | Reduced |
| Harbor Capital Advisors, Inc. | 60,304 | $1.29M | 0.25% | +8,025+15.4% | Added |