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Denali Therapeutics Inc.

DNLI
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001714899

In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.

13F holders, Q4 2023

Institutional positions in Denali Therapeutics Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
209
+16 vs. Q3 2023
Shares held
115.0M
+6.57M (+6.1%) vs. Q3 2023
Total value
$2.47B
+$224.9M (+10.0%) vs. Q3 2023
New holders
37
71 more added
Sold out
21
69 more reduced

2 institutions that held it in Q3 2023 haven't filed for Q4 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2023: 209 institutions
Q1 2021: 218 institutionsQ2 2021: 210 institutionsQ3 2021: 214 institutionsQ4 2021: 213 institutionsQ1 2022: 190 institutionsQ2 2022: 188 institutionsQ3 2022: 200 institutionsQ4 2022: 199 institutionsQ1 2023: 202 institutionsQ2 2023: 203 institutionsQ3 2023: 195 institutionsQ4 2023: 209 institutionsQ1 2024: 211 institutionsQ2 2024: 203 institutionsQ3 2024: 217 institutionsQ4 2024: 224 institutionsQ1 2025: 222 institutionsQ2 2025: 231 institutionsQ3 2025: 240 institutionsQ4 2025: 250 institutionsQ1 2026: 269 institutionsQ2 2026: 294 institutions
Value heldQ4 2023: $2.47B
Q1 2021: $4.60BQ2 2021: $6.32BQ3 2021: $4.28BQ4 2021: $3.80BQ1 2022: $2.79BQ2 2022: $2.73BQ3 2022: $2.84BQ4 2022: $2.94BQ1 2023: $2.49BQ2 2023: $3.18BQ3 2023: $2.24BQ4 2023: $2.47BQ1 2024: $2.51BQ2 2024: $2.88BQ3 2024: $3.69BQ4 2024: $2.61BQ1 2025: $1.85BQ2 2025: $1.93BQ3 2025: $1.97BQ4 2025: $2.50BQ1 2026: $2.82BQ2 2026: $4.00B
Institutions holding DNLI and their total value by quarter
QuarterHoldersValue
Q2 2026294$4.00B
Q1 2026269$2.82B
Q4 2025250$2.50B
Q3 2025240$1.97B
Q2 2025231$1.93B
Q1 2025222$1.85B
Q4 2024224$2.61B
Q3 2024217$3.69B
Q2 2024203$2.88B
Q1 2024211$2.51B
Q4 2023209$2.47B
Q3 2023195$2.24B
Q2 2023203$3.18B
Q1 2023202$2.49B
Q4 2022199$2.94B
Q3 2022200$2.84B
Q2 2022188$2.73B
Q1 2022190$2.79B
Q4 2021213$3.80B
Q3 2021214$4.28B
Q2 2021210$6.32B
Q1 2021218$4.60B

Institutions, Q4 2023

Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q3 2023.

Institutions holding DNLI in Q4 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Toronto Dominion Bank2$430.00%00.0%Unchanged
Global Retirement Partners, LLC3$550.00%00.0%Unchanged
Versant Capital Management, Inc8$1720.00%+8New
Institutional & Family Asset Management, LLC11$2360.00%00.0%Unchanged
Quadrant Capital Group LLC19$4080.00%+12+171.4%Added
Glassman Wealth Services29$6220.00%−17−37.0%Reduced
Naples Money Management LLC33$7080.00%+33New
GAMMA Investing LLC46$7360.00%+46New
Private Wealth Management Group, LLC49$1.05K0.00%+49New
Cubist Systematic Strategies, LLC77$1.65K0.00%+77New
Bell Investment Advisors, Inc77$1.65K0.00%+34+79.1%Added
Parallel Advisors, LLC83$1.78K0.00%−237−74.1%Reduced
Farther Finance Advisors, LLC84$1.80K0.00%+84New
Your Advocates Ltd., LLP100$2.15K0.00%00.0%Unchanged
Massmutual Trust Co FSB117$2.51K0.00%+84+254.5%Added
Activest Wealth Management131$2.81K0.00%00.0%Unchanged
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.145$2.95K0.00%00.0%Unchanged
First Horizon Advisors, Inc.220$4.72K0.00%00.0%Unchanged
City State Bank250$5.00K0.00%00.0%Unchanged
EverSource Wealth Advisors, LLC258$5.54K0.00%+42+19.4%Added
Morton Brown Family Wealth, LLC298$6.39K0.00%+298New
Advisory Services Network, LLC309$6.63K0.00%+309New
NBC Securities, Inc.335$7.00K0.00%00.0%Unchanged
Huntington National Bank350$7.51K0.00%−5−1.4%Reduced
Cutler Group LP400$8.00K0.00%+400New
US Bancorp499$10.7K0.00%−341−40.6%Reduced
Daiwa Securities Group Inc.546$12.0K0.00%00.0%Unchanged
Comerica Bank611$13.1K0.00%+293+92.1%Added
Lindbrook Capital, LLC646$13.9K0.00%+407+170.3%Added
Nemes Rush Group LLC700$15.0K0.00%00.0%Unchanged
Principal Securities, Inc.806$17.3K0.00%+806New
Allworth Financial LP889$19.1K0.00%+840+1,714.3%Added
Signaturefd, LLC920$19.7K0.00%+294+47.0%Added
Advisor Group Holdings, Inc.1,512$32.4K0.00%−3,165−67.7%Reduced
Bartlett & Co. Wealth Management LLC1,500$32.9K0.00%−23,300−94.0%Reduced
Bartlett & Co. LLC1,500$33.0K0.00%−23,300−94.0%Reduced
CWM, LLC2,011$43.0K0.00%+1,376+216.7%Added
KBC Group NV2,465$53.0K0.00%00.0%Unchanged
The PNC Financial Services Group, Inc.2,486$53.3K0.00%+807+48.1%Added
Caption Management, LLC3,000$64.4K0.01%+3,000New
Tao Capital Management LP3,042$66.0K0.06%+3,042New
Assetmark, Inc3,550$76.2K0.00%+1,402+65.3%Added
Virtus ETF Advisers LLC3,994$85.7K0.05%+949+31.2%Added
Lazard Asset Management LLC4,410$94.0K0.00%−6,451−59.4%Reduced
Allspring Global Investments Holdings, LLC5,641$121.1K0.00%+475+9.2%Added
Tower Research Capital LLC (TRC)5,724$122.8K0.00%+4,016+235.1%Added
Metropolitan Life Insurance Co6,806$146.1K0.01%00.0%Unchanged
Covestor Ltd7,155$154.0K0.11%+6,865+2,367.2%Added
Aquatic Capital Management LLC8,300$178.0K0.00%−10,000−54.6%Reduced
Brandywine Managers, LLC9,601$206.0K0.23%+9,601New
Great West Life Assurance Co9,724$207.0K0.00%00.0%Unchanged
Quest Partners LLC9,965$213.8K0.05%+9,965New
Prelude Capital Management, LLC10,344$222.0K0.02%+40+0.4%Added
Arthur M. Cohen & Associates, LLC10,564$226.7K0.05%−2,377−18.4%Reduced
SEI Investments Co11,861$254.5K0.00%−399−3.3%Reduced
Ameritas Investment Partners, Inc.12,230$262.5K0.01%+492+4.2%Added
Public Employees Retirement Association of Colorado12,238$263.0K0.00%00.0%Unchanged
Engineers Gate Manager LP12,672$271.9K0.01%−10,937−46.3%Reduced
Sectoral Asset Management Inc12,881$276.4K0.12%−242,060−94.9%Reduced
Stifel Financial Corp12,895$276.7K0.00%+541+4.4%Added
STRS Ohio13,800$296.0K0.00%00.0%Unchanged
Squarepoint Ops LLC14,319$307.3K0.00%−95,750−87.0%Reduced
Victory Capital Management Inc15,348$329.4K0.00%+3,267+27.0%Added
Allianz Asset Management GmbH15,400$330.5K0.00%+700+4.8%Added
Virtu Financial LLC15,576$334.0K0.03%+15,576New
China Universal Asset Management Co., Ltd.15,981$343.0K0.07%+12,455+353.2%Added
Walleye Capital LLC16,728$359.0K0.01%+16,728New
HSBC Holdings PLC16,892$364.0K0.00%−535−3.1%Reduced
Amalgamated Bank17,057$366.0K0.00%−1,198−6.6%Reduced
E Fund Management Co., Ltd.17,290$371.0K0.02%+5,509+46.8%Added
Guggenheim Capital LLC17,396$373.3K0.00%−39,974−69.7%Reduced
Ironwood Investment Management LLC17,938$384.9K0.20%−158−0.9%Reduced
Schonfeld Strategic Advisors LLC18,327$393.3K0.00%+18,327New
Employees Retirement System of Texas21,375$459.0K0.01%+21,375New
Zurcher Kantonalbank (Zurich Cantonalbank)22,787$489.0K0.00%+2,108+10.2%Added
Capstone Investment Advisors, LLC22,889$491.2K0.01%−14,678−39.1%Reduced
Envestnet Asset Management Inc23,561$505.6K0.00%+440+1.9%Added
Handelsbanken Fonder AB23,900$513.0K0.00%+6,700+39.0%Added
Levin Capital Strategies, L.P.24,000$515.0K0.06%+10,000+71.4%Added
Dana Investment Advisors, Inc.24,057$516.3K0.02%−572−2.3%Reduced
Landscape Capital Management, L.L.C.24,318$521.9K0.05%+24,318New
Creative Planning24,810$532.4K0.00%+10,394+72.1%Added
Teacher Retirement System of Texas25,426$546.0K0.00%−5,676−18.2%Reduced
VELA Investment Management, LLC26,145$561.1K0.23%+6,246+31.4%Added
Dynamic Technology Lab Private Ltd27,429$589.0K0.06%+4,340+18.8%Added
Erste Asset Management GmbH26,900$590.5K0.01%−307,769−92.0%Reduced
Two Sigma Investments, LP28,376$608.9K0.00%+28,376New
ProShare Advisors LLC28,385$609.1K0.00%+4,053+16.7%Added
Thrivent Financial for Lutherans29,682$637.0K0.00%+29,682New
University of Texas/Texas Am Investment Managment Co30,428$653.0K0.18%+30,428New
Arizona State Retirement System30,733$659.5K0.01%−448−1.4%Reduced
PDT Partners, LLC32,900$706.0K0.08%+32,900New
State Board of Administration of Florida Retirement System33,718$723.6K0.00%00.0%Unchanged
UBS Oconnor LLC34,464$739.6K0.02%−24,488−41.5%Reduced
Groupama Asset Managment35,013$751.6K0.02%+35,013New
Concentric Wealth Management, LLC36,486$783.0K0.23%00.0%Unchanged
Royal Bank of Canada38,841$834.0K0.00%+20,867+116.1%Added
HighTower Advisors, LLC39,633$858.0K0.00%−14,699−27.1%Reduced
ClariVest Asset Management LLC40,180$862.3K0.05%−2,721−6.3%Reduced
Twinbeech Capital LP40,580$870.8K0.01%+40,580New