Denali Therapeutics Inc.
DNLI- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.
13F holders, Q2 2022
Institutional positions in Denali Therapeutics Inc. as of Jun 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 188
- +2 vs. Q1 2022
- Shares held
- 92.7M
- +6.15M (+7.1%) vs. Q1 2022
- Total value
- $2.73B
- −$55.8M (−2.0%) vs. Q1 2022
- New holders
- 21
- 72 more added
- Sold out
- 19
- 58 more reduced
4 institutions that held it in Q1 2022 haven't filed for Q2 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 294 | $4.00B |
| Q1 2026 | 269 | $2.82B |
| Q4 2025 | 250 | $2.50B |
| Q3 2025 | 240 | $1.97B |
| Q2 2025 | 231 | $1.93B |
| Q1 2025 | 222 | $1.85B |
| Q4 2024 | 224 | $2.61B |
| Q3 2024 | 217 | $3.69B |
| Q2 2024 | 203 | $2.88B |
| Q1 2024 | 211 | $2.51B |
| Q4 2023 | 209 | $2.47B |
| Q3 2023 | 195 | $2.24B |
| Q2 2023 | 203 | $3.18B |
| Q1 2023 | 202 | $2.49B |
| Q4 2022 | 199 | $2.94B |
| Q3 2022 | 200 | $2.84B |
| Q2 2022 | 188 | $2.73B |
| Q1 2022 | 190 | $2.79B |
| Q4 2021 | 213 | $3.80B |
| Q3 2021 | 214 | $4.28B |
| Q2 2021 | 210 | $6.32B |
| Q1 2021 | 218 | $4.60B |
Institutions, Q2 2022
Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q1 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Baillie Gifford & Co | 14,869,374 | $437.6M | 0.45% | −111,058−0.7% | Reduced |
| BlackRock Inc. | 8,784,632 | $258.5M | 0.01% | +598,892+7.3% | Added |
| Vanguard Group Inc | 8,302,501 | $244.3M | 0.01% | +190,471+2.3% | Added |
| Crestline Management, LP | 7,460,732 | $219.6M | 28.78% | 00.0% | Unchanged |
| Temasek Holdings (Private) Ltd | 5,369,487 | $158.0M | 0.87% | 00.0% | Unchanged |
| ARCH Venture Management, LLC | 5,168,749 | $152.1M | 18.54% | +5,168,749 | New |
| Price T Rowe Associates Inc | 4,610,177 | $135.7M | 0.02% | −313,248−6.4% | Reduced |
| State Street Corp | 3,750,700 | $110.4M | 0.01% | −76,092−2.0% | Reduced |
| FMR LLC | 2,869,740 | $84.5M | 0.01% | −74,315−2.5% | Reduced |
| Flagship Pioneering Inc. | 2,619,968 | $77.1M | 2.90% | 00.0% | Unchanged |
| Credit Suisse AG | 1,960,025 | $57.7M | 0.06% | +1,451+0.1% | Added |
| Gilder Gagnon Howe & Co LLC | 1,956,820 | $57.6M | 1.03% | −662,397−25.3% | Reduced |
| Bank of New York Mellon Corp | 1,868,130 | $55.0M | 0.01% | +258,913+16.1% | Added |
| Geode Capital Management, LLC | 1,706,581 | $50.2M | 0.01% | +75,634+4.6% | Added |
| Casdin Capital, LLC | 1,500,000 | $44.1M | 3.73% | 00.0% | Unchanged |
| Pictet Asset Management SA | 1,015,158 | $29.9M | 0.04% | −8,405−0.8% | Reduced |
| Yiheng Capital Management, L.P. | 1,014,684 | $29.9M | 2.14% | 00.0% | Unchanged |
| Dimensional Fund Advisors LP | 891,678 | $26.2M | 0.01% | +13,454+1.5% | Added |
| Northern Trust Corp | 890,618 | $26.2M | 0.01% | −15,610−1.7% | Reduced |
| Norges Bank | 831,809 | $24.5M | 0.01% | −14,254−1.7% | Reduced |
| Marshall Wace, LLP | 817,650 | $24.1M | 0.05% | +664,795+434.9% | Added |
| Charles Schwab Investment Management Inc | 731,522 | $21.5M | 0.01% | +27,271+3.9% | Added |
| Federated Hermes, Inc. | 668,929 | $19.7M | 0.05% | −236,316−26.1% | Reduced |
| Millennium Management LLC | 645,336 | $19.0M | 0.02% | +645,336 | New |
| Artal Group S.A. | 600,000 | $17.7M | 0.98% | 00.0% | Unchanged |
| Baker Bros. Advisors LP | 588,738 | $17.3M | 0.10% | +500,000+563.5% | Added |
| UBS Asset Management Americas Inc | 487,405 | $14.3M | 0.01% | +52,578+12.1% | Added |
| American Century Companies Inc | 469,281 | $13.8M | 0.01% | −67,190−12.5% | Reduced |
| Artisan Partners Limited Partnership | 450,689 | $13.3M | 0.02% | −73,442−14.0% | Reduced |
| Morgan Stanley | 423,011 | $12.4M | 0.00% | −282,644−40.1% | Reduced |
| Goldman Sachs Group Inc | 420,742 | $12.4M | 0.00% | +14,514+3.6% | Added |
| Barclays PLC | 368,771 | $10.9M | 0.01% | +310,639+534.4% | Added |
| Nuveen Asset Management, LLC | 360,158 | $10.6M | 0.00% | −10,071−2.7% | Reduced |
| Wasatch Advisors Inc | 341,674 | $10.1M | 0.06% | +104,251+43.9% | Added |
| Candriam Luxembourg S.C.A. | 322,882 | $9.50M | 0.08% | +181,375+128.2% | Added |
| Mitsubishi UFJ Trust & Banking Corp | 314,890 | $9.27M | 0.02% | 00.0% | Unchanged |
| Citadel Advisors LLC | 306,002 | $9.01M | 0.01% | −445,601−59.3% | Reduced |
| Bamco Inc | 275,705 | $8.11M | 0.03% | −379,643−57.9% | Reduced |
| Principal Financial Group Inc | 267,732 | $7.88M | 0.01% | −1,272−0.5% | Reduced |
| Eagle Asset Management Inc | 263,704 | $7.76M | 0.05% | +59,854+29.4% | Added |
| Renaissance Technologies LLC | 253,500 | $7.46M | 0.01% | +130,900+106.8% | Added |
| AXA S.A. | 247,691 | $7.29M | 0.03% | +47,123+23.5% | Added |
| Voya Investment Management LLC | 230,830 | $6.79M | 0.02% | +99,848+76.2% | Added |
| Tekla Capital Management LLC | 222,420 | $6.55M | 0.26% | 00.0% | Unchanged |
| Skandinaviska Enskilda Banken AB (publ) | 212,823 | $6.26M | 0.05% | +74,324+53.7% | Added |
| California Public Employees Retirement System | 202,177 | $5.95M | 0.01% | 00.0% | Unchanged |
| Sectoral Asset Management Inc | 202,100 | $5.95M | 1.20% | −5,000−2.4% | Reduced |
| Swiss National Bank | 201,400 | $5.93M | 0.00% | +13,700+7.3% | Added |
| Woodline Partners LP | 180,972 | $5.33M | 0.09% | −75,706−29.5% | Reduced |
| Two Sigma Advisers, LP | 160,500 | $4.72M | 0.01% | −11,700−6.8% | Reduced |
| Alliancebernstein L.P. | 154,960 | $4.56M | 0.00% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 140,829 | $4.14M | 0.01% | +5,988+4.4% | Added |
| TD Asset Management Inc | 121,223 | $3.57M | 0.00% | −11,814−8.9% | Reduced |
| Manufacturers Life Insurance Company, The | 120,287 | $3.50M | 0.00% | +2,202+1.9% | Added |
| Bank of America Corp | 119,067 | $3.50M | 0.00% | −122,168−50.6% | Reduced |
| Rhumbline Advisers | 117,475 | $3.46M | 0.01% | +20,330+20.9% | Added |
| California State Teachers Retirement System | 114,884 | $3.38M | 0.01% | +8,291+7.8% | Added |
| Citigroup Inc | 111,814 | $3.29M | 0.00% | +76,430+216.0% | Added |
| Deutsche Bank AG | 110,297 | $3.25M | 0.00% | −2,617−2.3% | Reduced |
| Rafferty Asset Management, LLC | 101,471 | $2.99M | 0.03% | −74,491−42.3% | Reduced |
| JPMorgan Chase & Co | 100,025 | $2.94M | 0.00% | +2,653+2.7% | Added |
| Edmond de Rothschild Holding S.A. | 99,880 | $2.94M | 0.07% | 00.0% | Unchanged |
| State of New Jersey Common Pension Fund D | 91,898 | $2.71M | 0.01% | +14,967+19.5% | Added |
| Russell Investments Group, Ltd. | 88,230 | $2.60M | 0.01% | +36,710+71.3% | Added |
| State of Wisconsin Investment Board | 87,139 | $2.56M | 0.01% | −34,661−28.5% | Reduced |
| Legal & General Group Plc | 86,503 | $2.55M | 0.00% | +7,077+8.9% | Added |
| D. E. Shaw & Co., Inc. | 86,113 | $2.53M | 0.00% | +79,865+1,278.2% | Added |
| Ensign Peak Advisors, Inc | 85,672 | $2.52M | 0.01% | −18,904−18.1% | Reduced |
| Northwest & Ethical Investments L.P. | 79,880 | $2.35M | 0.09% | 00.0% | Unchanged |
| Invesco Ltd. | 73,666 | $2.17M | 0.00% | +6,032+8.9% | Added |
| Alps Advisors Inc | 72,940 | $2.15M | 0.02% | +72,940 | New |
| Cubist Systematic Strategies, LLC | 71,904 | $2.12M | 0.02% | +55,735+344.7% | Added |
| Wells Fargo & Company | 69,206 | $2.04M | 0.00% | −41,062−37.2% | Reduced |
| Natixis | 69,030 | $2.03M | 0.01% | −167,658−70.8% | Reduced |
| Two Sigma Investments, LP | 64,324 | $1.89M | 0.01% | +34,323+114.4% | Added |
| Putnam Investments LLC | 64,276 | $1.89M | 0.00% | +333+0.5% | Added |
| ExodusPoint Capital Management, LP | 64,187 | $1.89M | 0.03% | +64,187 | New |
| Guggenheim Capital LLC | 61,007 | $1.79M | 0.01% | +6,580+12.1% | Added |
| DekaBank Deutsche Girozentrale | 59,800 | $1.71M | 0.00% | 00.0% | Unchanged |
| ClariVest Asset Management LLC | 54,638 | $1.61M | 0.07% | −11,000−16.8% | Reduced |
| Platinum Investment Management Ltd | 50,971 | $1.50M | 0.06% | 00.0% | Unchanged |
| MetLife Investment Management | 50,392 | $1.48M | 0.01% | 00.0% | Unchanged |
| Voloridge Investment Management, LLC | 48,058 | $1.41M | 0.01% | +10,669+28.5% | Added |
| American International Group, Inc. | 46,116 | $1.36M | 0.01% | +945+2.1% | Added |
| Los Angeles Capital Management LLC | 43,919 | $1.29M | 0.01% | +1,667+3.9% | Added |
| SG Americas Securities, LLC | 39,316 | $1.16M | 0.02% | +30,336+337.8% | Added |
| AIA Group Ltd | 37,064 | $1.09M | 0.06% | −4,321−10.4% | Reduced |
| PDT Partners, LLC | 36,341 | $1.07M | 0.09% | +18,491+103.6% | Added |
| Mirae Asset Global Investments Co., Ltd. | 35,234 | $1.04M | 0.00% | +35,234 | New |
| STRS Ohio | 33,700 | $991.0K | 0.00% | +2,800+9.1% | Added |
| State Board of Administration of Florida Retirement System | 32,288 | $950.0K | 0.00% | +1,820+6.0% | Added |
| Envestnet Asset Management Inc | 30,443 | $896.0K | 0.00% | −2,915−8.7% | Reduced |
| Clarius Group, LLC | 28,519 | $839.0K | 0.08% | +2,074+7.8% | Added |
| Concentric Wealth Management, LLC | 27,967 | $823.0K | 0.28% | 00.0% | Unchanged |
| Erste Asset Management GmbH | 26,900 | $779.6K | 0.02% | 00.0% | Unchanged |
| Mercer Global Advisors Inc | 23,863 | $702.0K | 0.00% | +948+4.1% | Added |
| HRT Financial LP | 23,600 | $694.0K | 0.01% | +23,600 | New |
| Arizona State Retirement System | 23,167 | $682.0K | 0.01% | +1,709+8.0% | Added |
| BNP Paribas Arbitrage, SA | 22,332 | $657.2K | 0.00% | +14,089+170.9% | Added |
| ProShare Advisors LLC | 22,174 | $653.0K | 0.00% | −9,707−30.4% | Reduced |