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Denali Therapeutics Inc.

DNLI
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001714899

In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.

13F holders, Q2 2024

Institutional positions in Denali Therapeutics Inc. as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
203
−6 vs. Q1 2024
Shares held
123.9M
+3.03M (+2.5%) vs. Q1 2024
Total value
$2.88B
+$396.3M (+16.0%) vs. Q1 2024
New holders
29
84 more added
Sold out
35
60 more reduced

2 institutions that held it in Q1 2024 haven't filed for Q2 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2024: 203 institutions
Q1 2021: 218 institutionsQ2 2021: 210 institutionsQ3 2021: 214 institutionsQ4 2021: 213 institutionsQ1 2022: 190 institutionsQ2 2022: 188 institutionsQ3 2022: 200 institutionsQ4 2022: 199 institutionsQ1 2023: 202 institutionsQ2 2023: 203 institutionsQ3 2023: 195 institutionsQ4 2023: 209 institutionsQ1 2024: 211 institutionsQ2 2024: 203 institutionsQ3 2024: 217 institutionsQ4 2024: 224 institutionsQ1 2025: 222 institutionsQ2 2025: 231 institutionsQ3 2025: 240 institutionsQ4 2025: 250 institutionsQ1 2026: 269 institutionsQ2 2026: 294 institutions
Value heldQ2 2024: $2.88B
Q1 2021: $4.60BQ2 2021: $6.32BQ3 2021: $4.28BQ4 2021: $3.80BQ1 2022: $2.79BQ2 2022: $2.73BQ3 2022: $2.84BQ4 2022: $2.94BQ1 2023: $2.49BQ2 2023: $3.18BQ3 2023: $2.24BQ4 2023: $2.47BQ1 2024: $2.51BQ2 2024: $2.88BQ3 2024: $3.69BQ4 2024: $2.61BQ1 2025: $1.85BQ2 2025: $1.93BQ3 2025: $1.97BQ4 2025: $2.50BQ1 2026: $2.82BQ2 2026: $4.00B
Institutions holding DNLI and their total value by quarter
QuarterHoldersValue
Q2 2026294$4.00B
Q1 2026269$2.82B
Q4 2025250$2.50B
Q3 2025240$1.97B
Q2 2025231$1.93B
Q1 2025222$1.85B
Q4 2024224$2.61B
Q3 2024217$3.69B
Q2 2024203$2.88B
Q1 2024211$2.51B
Q4 2023209$2.47B
Q3 2023195$2.24B
Q2 2023203$3.18B
Q1 2023202$2.49B
Q4 2022199$2.94B
Q3 2022200$2.84B
Q2 2022188$2.73B
Q1 2022190$2.79B
Q4 2021213$3.80B
Q3 2021214$4.28B
Q2 2021210$6.32B
Q1 2021218$4.60B

Institutions, Q2 2024

Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q1 2024.

Institutions holding DNLI in Q2 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Baillie Gifford & Co13,763,596$319.6M0.25%−277,632−2.0%Reduced
BlackRock Inc.13,174,562$305.9M0.01%+974,706+8.0%Added
Vanguard Group Inc11,312,439$262.7M0.01%+344,146+3.1%Added
Wellington Management Group LLP9,823,767$228.1M0.04%+1,553,818+18.8%Added
Capital Research Global Investors7,126,533$165.5M0.04%+1,076,576+17.8%Added
Temasek Holdings (Private) Ltd5,706,345$132.5M0.62%00.0%Unchanged
Crestline Management, LP4,760,732$110.5M8.67%−450,000−8.6%Reduced
State Street Corp4,434,790$103.0M0.00%−1,889,082−29.9%Reduced
Takeda Pharmaceutical Co Ltd4,214,559$97.9M42.13%00.0%Unchanged
Baker Bros. Advisors LP3,731,695$86.6M1.11%00.0%Unchanged
Geode Capital Management, LLC2,982,538$69.3M0.01%+222,905+8.1%Added
Marshall Wace, LLP2,418,833$56.2M0.08%+272,454+12.7%Added
UBS Asset Management Americas Inc2,297,716$53.4M0.02%+1,610,477+234.3%Added
Price T Rowe Associates Inc2,255,470$52.4M0.01%+661,137+41.5%Added
Alliancebernstein L.P.2,018,534$46.9M0.02%+1,880,914+1,366.7%Added
Camber Capital Management LP2,000,000$46.4M1.79%+500,000+33.3%Added
Bank of New York Mellon Corp1,540,271$35.8M0.01%−237,636−13.4%Reduced
Dimensional Fund Advisors LP1,417,472$32.9M0.01%+84,522+6.3%Added
Casdin Capital, LLC1,300,000$30.2M2.30%00.0%Unchanged
Morgan Stanley1,223,878$28.4M0.00%+295,752+31.9%Added
Goldman Sachs Group Inc1,218,925$28.3M0.01%+314,564+34.8%Added
Citadel Advisors LLC1,218,698$28.3M0.03%−146,330−10.7%Reduced
Yiheng Capital Management, L.P.1,150,684$26.7M3.77%00.0%Unchanged
Artisan Partners Limited Partnership1,141,517$26.5M0.04%+775,685+212.0%Added
Principal Financial Group Inc1,088,537$25.3M0.02%−33,999−3.0%Reduced
Northern Trust Corp1,082,959$25.1M0.00%−5,554−0.5%Reduced
Nuveen Asset Management, LLC1,073,857$24.9M0.01%+565,661+111.3%Added
Charles Schwab Investment Management Inc1,059,304$24.6M0.00%+18,245+1.8%Added
Point72 Asset Management, L.P.1,053,150$24.5M0.08%+1,053,150New
Norges Bank823,941$19.1M0.00%−411,825−33.3%Reduced
Bank of America Corp742,048$17.2M0.00%−109,928−12.9%Reduced
Candriam Luxembourg S.C.A.726,499$16.9M0.10%+278,621+62.2%Added
Cercano Management LLC625,000$14.5M0.39%00.0%Unchanged
Millennium Management LLC619,929$14.4M0.01%+229,313+58.7%Added
Standard Life Aberdeen plc573,035$13.3M0.03%+57,016+11.0%Added
American Century Companies Inc522,594$12.1M0.01%+63,058+13.7%Added
Artal Group S.A.502,899$11.7M0.30%00.0%Unchanged
Vestal Point Capital, LP500,000$11.6M0.87%+500,000New
Fisher Asset Management, LLC478,108$11.1M0.00%+8,939+1.9%Added
Clarius Group, LLC409,995$9.52M0.67%+17,777+4.5%Added
Wasatch Advisors Inc402,409$9.34M0.05%−261−0.1%Reduced
Ensign Peak Advisors, Inc346,304$8.04M0.01%00.0%Unchanged
Schroder Investment Management Group345,373$8.02M0.01%+345,373New
AXA S.A.344,785$8.01M0.02%−16,023−4.4%Reduced
Integral Health Asset Management, LLC325,000$7.55M0.75%+325,000New
StemPoint Capital LP251,010$5.83M1.71%+251,010New
FMR LLC234,870$5.45M0.00%−997,652−80.9%Reduced
Swiss National Bank232,800$5.41M0.00%+14,600+6.7%Added
Jane Street Group, LLC231,364$5.37M0.01%+182,648+374.9%Added
Deutsche Bank AG223,400$5.19M0.00%−7,031−3.1%Reduced
Susquehanna Fundamental Investments, LLC222,917$5.18M0.12%+11,900+5.6%Added
JPMorgan Chase & Co221,062$5.13M0.00%+82,122+59.1%Added
Teachers Retirement System of the State of Kentucky207,124$4.81M0.04%00.0%Unchanged
Edmond de Rothschild Holding S.A.205,680$4.78M0.08%00.0%Unchanged
Rhumbline Advisers194,859$4.52M0.00%+22,900+13.3%Added
TD Asset Management Inc179,152$4.16M0.00%+7,766+4.5%Added
Hudson Bay Capital Management LP175,000$4.06M0.03%−45,000−20.5%Reduced
Manufacturers Life Insurance Company, The172,281$4.00M0.00%+23,165+15.5%Added
Pier Capital, LLC165,486$3.84M0.57%−6,845−4.0%Reduced
New York State Common Retirement Fund163,945$3.81M0.00%+38,170+30.3%Added
Schonfeld Strategic Advisors LLC163,074$3.79M0.03%+163,074New
PDT Partners, LLC158,384$3.68M0.35%00.0%Unchanged
Rafferty Asset Management, LLC151,482$3.52M0.01%−283,427−65.2%Reduced
UBS Group AG136,223$3.16M0.00%−207,656−60.4%Reduced
Thrivent Financial for Lutherans130,504$3.03M0.01%+65,729+101.5%Added
Legal & General Group Plc129,346$3.00M0.00%+21,896+20.4%Added
Barclays PLC127,060$2.95M0.00%−24,500−16.2%Reduced
Squarepoint Ops LLC123,680$2.87M0.01%+58,806+90.6%Added
Balyasny Asset Management LLC120,612$2.80M0.01%−242,415−66.8%Reduced
Prudential Financial Inc116,743$2.71M0.00%+36,314+45.2%Added
Invesco Ltd.116,232$2.70M0.00%+1,830+1.6%Added
California State Teachers Retirement System115,954$2.69M0.00%+4,518+4.1%Added
Cinctive Capital Management LP112,323$2.61M0.14%+112,323New
Alps Advisors Inc111,239$2.58M0.02%+13,090+13.3%Added
State of New Jersey Common Pension Fund D103,096$2.39M0.01%−61,979−37.5%Reduced
Two Sigma Investments, LP94,867$2.20M0.01%−96,638−50.5%Reduced
BIT Capital GmbH86,177$2.00M0.18%+4,177+5.1%Added
Franklin Resources Inc77,140$1.79M0.00%+26,545+52.5%Added
State of Wisconsin Investment Board76,931$1.79M0.00%−3,462−4.3%Reduced
Northwest & Ethical Investments L.P.75,835$1.76M0.05%00.0%Unchanged
Mirae Asset Global ETFs Holdings Ltd.74,704$1.73M0.00%+74,704New
Wells Fargo & Company74,321$1.73M0.00%+9,538+14.7%Added
Groupama Asset Managment72,388$1.68M0.03%+28,561+65.2%Added
MetLife Investment Management71,810$1.67M0.01%+9,546+15.3%Added
Pier 88 Investment Partners LLC69,370$1.61M0.36%+29,400+73.6%Added
AIA Group Ltd69,344$1.61M0.05%+8,310+13.6%Added
Corebridge Financial, Inc.66,875$1.55M0.01%+66,875New
Nisa Investment Advisors, LLC66,322$1.54M0.01%+193+0.3%Added
Susquehanna International Group, LLP60,398$1.40M0.00%−44,242−42.3%Reduced
Holocene Advisors, LP59,042$1.37M0.01%−801,906−93.1%Reduced
DekaBank Deutsche Girozentrale59,800$1.37M0.00%−4,410−6.9%Reduced
Voya Investment Management LLC58,780$1.36M0.00%−161,858−73.4%Reduced
Tudor Investment Corp Et Al58,523$1.36M0.02%−13,128−18.3%Reduced
Knights of Columbus Asset Advisors LLC57,995$1.35M0.09%+18,554+47.0%Added
Woodline Partners LP56,554$1.31M0.01%−452,011−88.9%Reduced
Voloridge Investment Management, LLC54,056$1.26M0.00%−73,214−57.5%Reduced
Los Angeles Capital Management LLC52,863$1.23M0.00%−2,749−4.9%Reduced
Janus Henderson Group PLC52,128$1.21M0.00%−590−1.1%Reduced
Bayesian Capital Management, LP50,500$1.17M0.13%+28,700+131.7%Added
Concentric Wealth Management, LLC46,526$1.08M0.28%+10,040+27.5%Added