Denali Therapeutics Inc.
DNLI- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.
13F holders, Q1 2022
Institutional positions in Denali Therapeutics Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 190
- −21 vs. Q4 2021
- Shares held
- 86.8M
- +1.55M (+1.8%) vs. Q4 2021
- Total value
- $2.79B
- −$1.01B (−26.6%) vs. Q4 2021
- New holders
- 19
- 68 more added
- Sold out
- 40
- 69 more reduced
2 institutions that held it in Q4 2021 haven't filed for Q1 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 294 | $4.00B |
| Q1 2026 | 269 | $2.82B |
| Q4 2025 | 250 | $2.50B |
| Q3 2025 | 240 | $1.97B |
| Q2 2025 | 231 | $1.93B |
| Q1 2025 | 222 | $1.85B |
| Q4 2024 | 224 | $2.61B |
| Q3 2024 | 217 | $3.69B |
| Q2 2024 | 203 | $2.88B |
| Q1 2024 | 211 | $2.51B |
| Q4 2023 | 209 | $2.47B |
| Q3 2023 | 195 | $2.24B |
| Q2 2023 | 203 | $3.18B |
| Q1 2023 | 202 | $2.49B |
| Q4 2022 | 199 | $2.94B |
| Q3 2022 | 200 | $2.84B |
| Q2 2022 | 188 | $2.73B |
| Q1 2022 | 190 | $2.79B |
| Q4 2021 | 213 | $3.80B |
| Q3 2021 | 214 | $4.28B |
| Q2 2021 | 210 | $6.32B |
| Q1 2021 | 218 | $4.60B |
Institutions, Q1 2022
Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q4 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Baillie Gifford & Co | 14,980,432 | $481.9M | 0.34% | −75,949−0.5% | Reduced |
| BlackRock Inc. | 8,185,740 | $263.3M | 0.01% | +74,918+0.9% | Added |
| Vanguard Group Inc | 8,112,030 | $261.0M | 0.01% | −49,500−0.6% | Reduced |
| Crestline Management, LP | 7,460,732 | $240.0M | 30.17% | −244,307−3.2% | Reduced |
| Temasek Holdings (Private) Ltd | 5,369,487 | $172.7M | 0.73% | 00.0% | Unchanged |
| Price T Rowe Associates Inc | 4,923,425 | $158.4M | 0.02% | +287,992+6.2% | Added |
| State Street Corp | 3,826,792 | $123.1M | 0.01% | +799,221+26.4% | Added |
| FMR LLC | 2,944,055 | $94.7M | 0.01% | −7,736−0.3% | Reduced |
| Flagship Pioneering Inc. | 2,619,968 | $84.3M | 1.98% | 00.0% | Unchanged |
| Gilder Gagnon Howe & Co LLC | 2,619,217 | $84.3M | 0.78% | −280,897−9.7% | Reduced |
| Credit Suisse AG | 1,958,574 | $63.0M | 0.05% | −5,074−0.3% | Reduced |
| Geode Capital Management, LLC | 1,630,947 | $52.5M | 0.01% | +2,080+0.1% | Added |
| Bank of New York Mellon Corp | 1,609,217 | $51.8M | 0.01% | +676,625+72.6% | Added |
| Casdin Capital, LLC | 1,500,000 | $48.3M | 2.16% | 00.0% | Unchanged |
| Pictet Asset Management SA | 1,023,563 | $32.9M | 0.04% | +24,943+2.5% | Added |
| Yiheng Capital Management, L.P. | 1,014,684 | $32.6M | 2.09% | +679,500+202.7% | Added |
| Northern Trust Corp | 906,228 | $29.2M | 0.01% | −52,861−5.5% | Reduced |
| Federated Hermes, Inc. | 905,245 | $29.1M | 0.07% | +169,813+23.1% | Added |
| Dimensional Fund Advisors LP | 878,224 | $28.3M | 0.01% | +106,027+13.7% | Added |
| Norges Bank | 846,063 | $27.2M | 0.01% | −460.0% | Reduced |
| Citadel Advisors LLC | 751,603 | $24.2M | 0.03% | +265,920+54.8% | Added |
| Morgan Stanley | 705,655 | $22.7M | 0.00% | +418,397+145.7% | Added |
| Charles Schwab Investment Management Inc | 704,251 | $22.7M | 0.01% | −12,939−1.8% | Reduced |
| Bamco Inc | 655,348 | $21.1M | 0.05% | −340,956−34.2% | Reduced |
| Artal Group S.A. | 600,000 | $19.3M | 0.82% | 00.0% | Unchanged |
| American Century Companies Inc | 536,471 | $17.3M | 0.01% | +1890.0% | Added |
| Artisan Partners Limited Partnership | 524,131 | $16.9M | 0.02% | +2,723+0.5% | Added |
| UBS Asset Management Americas Inc | 434,827 | $14.0M | 0.01% | −5,209−1.2% | Reduced |
| Goldman Sachs Group Inc | 406,228 | $13.1M | 0.00% | −4,536−1.1% | Reduced |
| Nuveen Asset Management, LLC | 370,229 | $12.3M | 0.00% | −6,815−1.8% | Reduced |
| Mitsubishi UFJ Trust & Banking Corp | 314,890 | $10.1M | 0.02% | +5,850+1.9% | Added |
| Principal Financial Group Inc | 269,004 | $8.65M | 0.01% | −61,271−18.6% | Reduced |
| Woodline Partners LP | 256,678 | $8.26M | 0.14% | +204,224+389.3% | Added |
| Bank of America Corp | 241,235 | $7.76M | 0.00% | +112,287+87.1% | Added |
| Wasatch Advisors Inc | 237,423 | $7.64M | 0.04% | +63,181+36.3% | Added |
| Natixis | 236,688 | $7.61M | 0.03% | −56,866−19.4% | Reduced |
| Tekla Capital Management LLC | 222,420 | $7.16M | 0.25% | 00.0% | Unchanged |
| Sectoral Asset Management Inc | 207,100 | $6.66M | 1.18% | +17,500+9.2% | Added |
| Eagle Asset Management Inc | 203,850 | $6.56M | 0.03% | +12,334+6.4% | Added |
| California Public Employees Retirement System | 202,177 | $6.50M | 0.01% | 00.0% | Unchanged |
| AXA S.A. | 200,568 | $6.45M | 0.02% | −19,498−8.9% | Reduced |
| Swiss National Bank | 187,700 | $6.04M | 0.00% | +14,000+8.1% | Added |
| Rafferty Asset Management, LLC | 175,962 | $5.66M | 0.03% | +54,207+44.5% | Added |
| Two Sigma Advisers, LP | 172,200 | $5.54M | 0.01% | −97,400−36.1% | Reduced |
| Teachers Retirement System of the State of Kentucky | 171,496 | $5.52M | 0.05% | 00.0% | Unchanged |
| Alliancebernstein L.P. | 154,960 | $4.99M | 0.00% | +300+0.2% | Added |
| Marshall Wace, LLP | 152,855 | $4.92M | 0.01% | −231,089−60.2% | Reduced |
| Candriam Luxembourg S.C.A. | 141,507 | $4.55M | 0.03% | 00.0% | Unchanged |
| Skandinaviska Enskilda Banken AB (publ) | 138,499 | $4.46M | 0.03% | −640.0% | Reduced |
| New York State Common Retirement Fund | 134,841 | $4.34M | 0.00% | +540.0% | Added |
| TD Asset Management Inc | 133,037 | $4.28M | 0.00% | +10,700+8.7% | Added |
| Voya Investment Management LLC | 130,982 | $4.21M | 0.01% | +95,909+273.5% | Added |
| Renaissance Technologies LLC | 122,600 | $3.94M | 0.00% | +68,300+125.8% | Added |
| State of Wisconsin Investment Board | 121,800 | $3.92M | 0.01% | 00.0% | Unchanged |
| Manufacturers Life Insurance Company, The | 118,085 | $3.82M | 0.00% | +71,589+154.0% | Added |
| Deutsche Bank AG | 112,914 | $3.63M | 0.00% | −5,418−4.6% | Reduced |
| Wells Fargo & Company | 110,268 | $3.55M | 0.00% | −33,268−23.2% | Reduced |
| California State Teachers Retirement System | 106,593 | $3.43M | 0.00% | −9,922−8.5% | Reduced |
| Ensign Peak Advisors, Inc | 104,576 | $3.37M | 0.01% | +120+0.1% | Added |
| Edmond de Rothschild Holding S.A. | 99,880 | $3.21M | 0.07% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 97,372 | $3.13M | 0.00% | +14,227+17.1% | Added |
| Rhumbline Advisers | 97,145 | $3.13M | 0.00% | +496+0.5% | Added |
| Baker Bros. Advisors LP | 88,738 | $2.85M | 0.02% | 00.0% | Unchanged |
| Susquehanna International Group, LLP | 85,718 | $2.76M | 0.00% | −33,177−27.9% | Reduced |
| Janus Henderson Group PLC | 83,695 | $2.69M | 0.00% | −16,768−16.7% | Reduced |
| Northwest & Ethical Investments L.P. | 79,880 | $2.57M | 0.08% | +48,280+152.8% | Added |
| Legal & General Group Plc | 79,426 | $2.56M | 0.00% | +455+0.6% | Added |
| State of New Jersey Common Pension Fund D | 76,931 | $2.48M | 0.01% | +17,313+29.0% | Added |
| Invesco Ltd. | 67,634 | $2.18M | 0.00% | +23,170+52.1% | Added |
| ClariVest Asset Management LLC | 65,638 | $2.11M | 0.08% | 00.0% | Unchanged |
| Putnam Investments LLC | 63,943 | $2.06M | 0.00% | −12,917−16.8% | Reduced |
| DekaBank Deutsche Girozentrale | 59,800 | $1.94M | 0.00% | +5,400+9.9% | Added |
| Barclays PLC | 58,132 | $1.87M | 0.00% | −62,689−51.9% | Reduced |
| Guggenheim Capital LLC | 54,427 | $1.75M | 0.01% | +7,445+15.8% | Added |
| Russell Investments Group, Ltd. | 51,520 | $1.66M | 0.00% | −14,601−22.1% | Reduced |
| Platinum Investment Management Ltd | 50,971 | $1.64M | 0.05% | 00.0% | Unchanged |
| MetLife Investment Management | 50,392 | $1.62M | 0.01% | +18,003+55.6% | Added |
| American International Group, Inc. | 45,171 | $1.45M | 0.01% | −3,179−6.6% | Reduced |
| Los Angeles Capital Management LLC | 42,252 | $1.36M | 0.01% | +1,160+2.8% | Added |
| AIA Group Ltd | 41,385 | $1.33M | 0.06% | −66,457−61.6% | Reduced |
| Allspring Global Investments Holdings, LLC | 40,217 | $1.29M | 0.00% | +1,605+4.2% | Added |
| UBS Group AG | 39,112 | $1.26M | 0.00% | −53,236−57.6% | Reduced |
| Voloridge Investment Management, LLC | 37,389 | $1.20M | 0.01% | +23,448+168.2% | Added |
| Clarius Group, LLC | 26,445 | $1.18M | 0.09% | 00.0% | Unchanged |
| Citigroup Inc | 35,384 | $1.14M | 0.00% | −84,997−70.6% | Reduced |
| Squarepoint Ops LLC | 34,435 | $1.11M | 0.01% | +34,435 | New |
| Duality Advisers, LP | 34,200 | $1.10M | 0.12% | +34,200 | New |
| Envestnet Asset Management Inc | 33,358 | $1.07M | 0.00% | +4,795+16.8% | Added |
| ProShare Advisors LLC | 31,881 | $1.03M | 0.00% | −7,521−19.1% | Reduced |
| STRS Ohio | 30,900 | $994.0K | 0.00% | 00.0% | Unchanged |
| State Board of Administration of Florida Retirement System | 30,468 | $980.0K | 0.00% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 30,001 | $965.0K | 0.00% | +21,425+249.8% | Added |
| Walleye Capital LLC | 28,296 | $910.0K | 0.03% | +28,296 | New |
| Concentric Wealth Management, LLC | 27,967 | $900.0K | 0.26% | 00.0% | Unchanged |
| Parametric Portfolio Associates LLC | 27,557 | $887.0K | 0.00% | −4,887−15.1% | Reduced |
| AlphaCrest Capital Management LLC | 27,200 | $875.0K | 0.05% | +17,389+177.2% | Added |
| Erste Asset Management GmbH | 26,900 | $871.6K | 0.02% | −3,700−12.1% | Reduced |
| Integral Health Asset Management, LLC | 26,000 | $836.0K | 0.22% | −74,000−74.0% | Reduced |
| Eaton Vance Management | 23,057 | $742.0K | 0.00% | +23,057 | New |
| Mercer Global Advisors Inc | 22,915 | $737.0K | 0.00% | +5,563+32.1% | Added |