Denali Therapeutics Inc.
DNLI- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.
13F holders, Q1 2022
Institutional positions in Denali Therapeutics Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 190
- −21 vs. Q4 2021
- Shares held
- 86.8M
- +1.55M (+1.8%) vs. Q4 2021
- Total value
- $2.79B
- −$1.01B (−26.6%) vs. Q4 2021
- New holders
- 19
- 68 more added
- Sold out
- 40
- 69 more reduced
2 institutions that held it in Q4 2021 haven't filed for Q1 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 294 | $4.00B |
| Q1 2026 | 269 | $2.82B |
| Q4 2025 | 250 | $2.50B |
| Q3 2025 | 240 | $1.97B |
| Q2 2025 | 231 | $1.93B |
| Q1 2025 | 222 | $1.85B |
| Q4 2024 | 224 | $2.61B |
| Q3 2024 | 217 | $3.69B |
| Q2 2024 | 203 | $2.88B |
| Q1 2024 | 211 | $2.51B |
| Q4 2023 | 209 | $2.47B |
| Q3 2023 | 195 | $2.24B |
| Q2 2023 | 203 | $3.18B |
| Q1 2023 | 202 | $2.49B |
| Q4 2022 | 199 | $2.94B |
| Q3 2022 | 200 | $2.84B |
| Q2 2022 | 188 | $2.73B |
| Q1 2022 | 190 | $2.79B |
| Q4 2021 | 213 | $3.80B |
| Q3 2021 | 214 | $4.28B |
| Q2 2021 | 210 | $6.32B |
| Q1 2021 | 218 | $4.60B |
Institutions, Q1 2022
Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q4 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| AQR Capital Management LLC | 22,686 | $730.0K | 0.00% | −28,981−56.1% | Reduced |
| Arizona State Retirement System | 21,458 | $690.0K | 0.01% | +178+0.8% | Added |
| Prudential Financial Inc | 20,753 | $667.0K | 0.00% | −195,048−90.4% | Reduced |
| Ironwood Investment Management LLC | 19,842 | $638.0K | 0.35% | +459+2.4% | Added |
| Rockefeller Capital Management L.P. | 19,652 | $631.0K | 0.00% | +3,194+19.4% | Added |
| Bartlett & Co. Wealth Management LLC | 18,510 | $595.5K | 0.01% | +1,567+9.2% | Added |
| Bartlett & Co. LLC | 18,510 | $595.0K | 0.01% | +1,567+9.2% | Added |
| Twinbeech Capital LP | 18,046 | $581.0K | 0.03% | +18,046 | New |
| Allianz Asset Management GmbH | 17,820 | $574.0K | 0.00% | −18,325−50.7% | Reduced |
| PDT Partners, LLC | 17,850 | $574.0K | 0.05% | +17,850 | New |
| Teacher Retirement System of Texas | 16,488 | $530.0K | 0.00% | +919+5.9% | Added |
| Cubist Systematic Strategies, LLC | 16,169 | $520.0K | 0.00% | +8,303+105.6% | Added |
| Engineers Gate Manager LP | 16,046 | $516.0K | 0.02% | +10,356+182.0% | Added |
| Algert Global LLC | 15,203 | $489.0K | 0.03% | +7,834+106.3% | Added |
| Amalgamated Bank | 14,893 | $479.0K | 0.00% | −1,119−7.0% | Reduced |
| Amalgamated Financial Corp. | 14,893 | $479.0K | 0.00% | +14,893 | New |
| Virginia Retirement Systems Et Al | 14,600 | $470.0K | 0.00% | −11,100−43.2% | Reduced |
| Profund Advisors LLC | 14,254 | $459.0K | 0.02% | −1,586−10.0% | Reduced |
| First Trust Advisors LP | 14,224 | $458.0K | 0.00% | −923−6.1% | Reduced |
| Stifel Financial Corp | 13,640 | $439.0K | 0.00% | −15−0.1% | Reduced |
| Capital Fund Management S.A. | 13,443 | $432.5K | 0.01% | −360−2.6% | Reduced |
| Arthur M. Cohen & Associates, LLC | 12,416 | $399.0K | 0.08% | 00.0% | Unchanged |
| Public Employees Retirement Association of Colorado | 12,238 | $394.0K | 0.00% | 00.0% | Unchanged |
| Handelsbanken Fonder AB | 11,800 | $380.0K | 0.00% | −6,200−34.4% | Reduced |
| Utah Retirement Systems | 11,600 | $373.0K | 0.00% | 00.0% | Unchanged |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 11,390 | $366.0K | 0.00% | +446+4.1% | Added |
| Dana Investment Advisors, Inc. | 11,296 | $363.0K | 0.02% | +1,658+17.2% | Added |
| SEI Investments Co | 10,518 | $328.0K | 0.00% | −834−7.3% | Reduced |
| Brandywine Managers, LLC | 9,601 | $309.0K | 0.53% | 00.0% | Unchanged |
| SG Americas Securities, LLC | 8,980 | $289.0K | 0.00% | −23,822−72.6% | Reduced |
| E Fund Management Co., Ltd. | 8,827 | $284.0K | 0.01% | +8,827 | New |
| GAM Holding AG | 8,403 | $270.0K | 0.01% | 00.0% | Unchanged |
| Royal Bank of Canada | 8,381 | $269.0K | 0.00% | −862−9.3% | Reduced |
| BNP Paribas Arbitrage, SA | 8,243 | $265.2K | 0.00% | −11,456−58.2% | Reduced |
| Victory Capital Management Inc | 10,883 | $259.0K | 0.00% | −1,198−9.9% | Reduced |
| Ameritas Investment Partners, Inc. | 7,134 | $230.0K | 0.01% | 00.0% | Unchanged |
| Group One Trading, L.P. | 6,959 | $224.0K | 0.00% | −7,386−51.5% | Reduced |
| Gsa Capital Partners LLP | 6,940 | $223.0K | 0.03% | +1,106+19.0% | Added |
| Bridgewater Associates, LP | 6,867 | $221.0K | 0.00% | +6,867 | New |
| Creative Planning | 6,780 | $218.0K | 0.00% | +1,572+30.2% | Added |
| Ergoteles LLC | 6,693 | $215.0K | 0.01% | +6,693 | New |
| D. E. Shaw & Co., Inc. | 6,248 | $201.0K | 0.00% | −988−13.7% | Reduced |
| Metropolitan Life Insurance Co | 5,579 | $179.5K | 0.01% | −18,510−76.8% | Reduced |
| Great West Life Assurance Co | 3,874 | $132.0K | 0.00% | −588−13.2% | Reduced |
| Virtus ETF Advisers LLC | 3,433 | $110.0K | 0.05% | −200−5.5% | Reduced |
| Amundi | 3,017 | $97.0K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 2,616 | $84.0K | 0.00% | −1,235−32.1% | Reduced |
| Advisor Group Holdings, Inc. | 2,317 | $75.0K | 0.00% | +214+10.2% | Added |
| Tower Research Capital LLC (TRC) | 2,097 | $68.0K | 0.00% | −5,242−71.4% | Reduced |
| Brown Brothers Harriman & Co | 2,024 | $65.0K | 0.00% | −7,000−77.6% | Reduced |
| High Net Worth Advisory Group LLC | 2,000 | $64.0K | 0.02% | −500−20.0% | Reduced |
| Itau Unibanco Holding S.A. | 1,948 | $63.0K | 0.00% | 00.0% | Unchanged |
| Macquarie Group Ltd | 1,411 | $45.0K | 0.00% | −40,750−96.7% | Reduced |
| Cutler Group LP | 1,300 | $41.0K | 0.00% | −400−23.5% | Reduced |
| Point72 Hong Kong Ltd | 1,194 | $38.0K | 0.00% | −125−9.5% | Reduced |
| State of Wyoming | 1,134 | $36.0K | 0.02% | +748+193.8% | Added |
| Aquatic Capital Management LLC | 1,100 | $35.0K | 0.05% | +1,100 | New |
| Patriot Financial Group Insurance Agency, LLC | 910 | $29.0K | 0.01% | +99+12.2% | Added |
| The PNC Financial Services Group, Inc. | 838 | $27.0K | 0.00% | −614−42.3% | Reduced |
| US Bancorp | 559 | $18.0K | 0.00% | +115+25.9% | Added |
| Exchange Traded Concepts, LLC | 492 | $16.0K | 0.00% | +492 | New |
| Umb Bank N A | 444 | $14.0K | 0.00% | +444 | New |
| Daiwa Securities Group Inc. | 356 | $11.0K | 0.00% | 00.0% | Unchanged |
| TCI Wealth Advisors, Inc. | 296 | $10.0K | 0.00% | +80+37.0% | Added |
| City State Bank | 250 | $8.00K | 0.00% | 00.0% | Unchanged |
| Covestor Ltd | 258 | $8.00K | 0.01% | +103+66.5% | Added |
| Lindbrook Capital, LLC | 204 | $7.00K | 0.00% | −407−66.6% | Reduced |
| Private Capital Group, LLC | 192 | $6.00K | 0.00% | +60+45.5% | Added |
| Captrust Financial Advisors | 171 | $6.00K | 0.00% | +52+43.7% | Added |
| Quantbot Technologies LP | 167 | $5.00K | 0.00% | −3,575−95.5% | Reduced |
| Leonteq Securities AG | 137 | $4.41K | 0.00% | +39+39.8% | Added |
| Huntington National Bank | 138 | $4.00K | 0.00% | +7+5.3% | Added |
| Activest Wealth Management | 131 | $4.00K | 0.00% | 00.0% | Unchanged |
| Asset Management One Co.,Ltd. | 100 | $3.00K | 0.00% | 00.0% | Unchanged |
| Your Advocates Ltd., LLP | 100 | $3.00K | 0.00% | 00.0% | Unchanged |
| Farmers & Merchants Investments Inc | 58 | $2.00K | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 51 | $2.00K | 0.00% | 00.0% | Unchanged |
| Signaturefd, LLC | 53 | $2.00K | 0.00% | +53 | New |
| Massmutual Trust Co FSB | 26 | $1.00K | 0.00% | +26 | New |
| TCWP LLC | 34 | $1.00K | 0.00% | +34 | New |
| Pier 88 Investment Partners LLC | 10 | $0 | 0.00% | −33,070−100.0% | Reduced |
| First Horizon Advisors, Inc. | 15 | $0 | 0.00% | −200−93.0% | Reduced |
| Parallel Advisors, LLC | 2 | $0 | 0.00% | −44−95.7% | Reduced |
| Toronto Dominion Bank | 2 | $0 | 0.00% | 00.0% | Unchanged |
| Ci Investments Inc. | 4 | $0 | 0.00% | 00.0% | Unchanged |
| Ellevest, Inc. | 3 | $0 | 0.00% | −8−72.7% | Reduced |
| Central Trust Co | 4 | $0 | 0.00% | +4 | New |
| Institutional & Family Asset Management, LLC | 6 | $0 | 0.00% | +6 | New |
| Global Retirement Partners, LLC | 3 | $0 | 0.00% | +3 | New |
| International Biotechnology Trust PLC | 38,000 | – | – | +12,000+46.2% | Added |
| Nomura Asset Management Co Ltd | 0 | $0 | 0.00% | −10,402−100.0% | Sold out |
| Jennison Associates LLC | 0 | $0 | 0.00% | −224,184−100.0% | Sold out |
| Goldstream Capital Management Ltd | 0 | $0 | 0.00% | −78,418−100.0% | Sold out |
| Polar Capital Holdings Plc | 0 | $0 | 0.00% | −53,835−100.0% | Sold out |
| Jupiter Asset Management Ltd | 0 | $0 | 0.00% | −50,023−100.0% | Sold out |
| Mark Asset Management LP | 0 | $0 | 0.00% | −40,370−100.0% | Sold out |
| Jane Street Group, LLC | 0 | $0 | 0.00% | −24,456−100.0% | Sold out |
| Millennium Management LLC | 0 | $0 | 0.00% | −18,360−100.0% | Sold out |
| Vontobel Holding Ltd. | 0 | $0 | 0.00% | −17,988−100.0% | Sold out |
| Balyasny Asset Management LLC | 0 | $0 | 0.00% | −12,874−100.0% | Sold out |