Denali Therapeutics Inc.
DNLI- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.
13F holders, Q1 2022
Institutional positions in Denali Therapeutics Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 190
- −21 vs. Q4 2021
- Shares held
- 86.8M
- +1.55M (+1.8%) vs. Q4 2021
- Total value
- $2.79B
- −$1.01B (−26.6%) vs. Q4 2021
- New holders
- 19
- 68 more added
- Sold out
- 40
- 69 more reduced
2 institutions that held it in Q4 2021 haven't filed for Q1 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 294 | $4.00B |
| Q1 2026 | 269 | $2.82B |
| Q4 2025 | 250 | $2.50B |
| Q3 2025 | 240 | $1.97B |
| Q2 2025 | 231 | $1.93B |
| Q1 2025 | 222 | $1.85B |
| Q4 2024 | 224 | $2.61B |
| Q3 2024 | 217 | $3.69B |
| Q2 2024 | 203 | $2.88B |
| Q1 2024 | 211 | $2.51B |
| Q4 2023 | 209 | $2.47B |
| Q3 2023 | 195 | $2.24B |
| Q2 2023 | 203 | $3.18B |
| Q1 2023 | 202 | $2.49B |
| Q4 2022 | 199 | $2.94B |
| Q3 2022 | 200 | $2.84B |
| Q2 2022 | 188 | $2.73B |
| Q1 2022 | 190 | $2.79B |
| Q4 2021 | 213 | $3.80B |
| Q3 2021 | 214 | $4.28B |
| Q2 2021 | 210 | $6.32B |
| Q1 2021 | 218 | $4.60B |
Institutions, Q1 2022
Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q4 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Pier 88 Investment Partners LLC | 10 | $0 | 0.00% | −33,070−100.0% | Reduced |
| First Horizon Advisors, Inc. | 15 | $0 | 0.00% | −200−93.0% | Reduced |
| Parallel Advisors, LLC | 2 | $0 | 0.00% | −44−95.7% | Reduced |
| Toronto Dominion Bank | 2 | $0 | 0.00% | 00.0% | Unchanged |
| Ci Investments Inc. | 4 | $0 | 0.00% | 00.0% | Unchanged |
| Ellevest, Inc. | 3 | $0 | 0.00% | −8−72.7% | Reduced |
| Central Trust Co | 4 | $0 | 0.00% | +4 | New |
| Institutional & Family Asset Management, LLC | 6 | $0 | 0.00% | +6 | New |
| Global Retirement Partners, LLC | 3 | $0 | 0.00% | +3 | New |
| Massmutual Trust Co FSB | 26 | $1.00K | 0.00% | +26 | New |
| TCWP LLC | 34 | $1.00K | 0.00% | +34 | New |
| Farmers & Merchants Investments Inc | 58 | $2.00K | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 51 | $2.00K | 0.00% | 00.0% | Unchanged |
| Signaturefd, LLC | 53 | $2.00K | 0.00% | +53 | New |
| Asset Management One Co.,Ltd. | 100 | $3.00K | 0.00% | 00.0% | Unchanged |
| Your Advocates Ltd., LLP | 100 | $3.00K | 0.00% | 00.0% | Unchanged |
| Huntington National Bank | 138 | $4.00K | 0.00% | +7+5.3% | Added |
| Activest Wealth Management | 131 | $4.00K | 0.00% | 00.0% | Unchanged |
| Leonteq Securities AG | 137 | $4.41K | 0.00% | +39+39.8% | Added |
| Quantbot Technologies LP | 167 | $5.00K | 0.00% | −3,575−95.5% | Reduced |
| Private Capital Group, LLC | 192 | $6.00K | 0.00% | +60+45.5% | Added |
| Captrust Financial Advisors | 171 | $6.00K | 0.00% | +52+43.7% | Added |
| Lindbrook Capital, LLC | 204 | $7.00K | 0.00% | −407−66.6% | Reduced |
| City State Bank | 250 | $8.00K | 0.00% | 00.0% | Unchanged |
| Covestor Ltd | 258 | $8.00K | 0.01% | +103+66.5% | Added |
| TCI Wealth Advisors, Inc. | 296 | $10.0K | 0.00% | +80+37.0% | Added |
| Daiwa Securities Group Inc. | 356 | $11.0K | 0.00% | 00.0% | Unchanged |
| Umb Bank N A | 444 | $14.0K | 0.00% | +444 | New |
| Exchange Traded Concepts, LLC | 492 | $16.0K | 0.00% | +492 | New |
| US Bancorp | 559 | $18.0K | 0.00% | +115+25.9% | Added |
| The PNC Financial Services Group, Inc. | 838 | $27.0K | 0.00% | −614−42.3% | Reduced |
| Patriot Financial Group Insurance Agency, LLC | 910 | $29.0K | 0.01% | +99+12.2% | Added |
| Aquatic Capital Management LLC | 1,100 | $35.0K | 0.05% | +1,100 | New |
| State of Wyoming | 1,134 | $36.0K | 0.02% | +748+193.8% | Added |
| Point72 Hong Kong Ltd | 1,194 | $38.0K | 0.00% | −125−9.5% | Reduced |
| Cutler Group LP | 1,300 | $41.0K | 0.00% | −400−23.5% | Reduced |
| Macquarie Group Ltd | 1,411 | $45.0K | 0.00% | −40,750−96.7% | Reduced |
| Itau Unibanco Holding S.A. | 1,948 | $63.0K | 0.00% | 00.0% | Unchanged |
| High Net Worth Advisory Group LLC | 2,000 | $64.0K | 0.02% | −500−20.0% | Reduced |
| Brown Brothers Harriman & Co | 2,024 | $65.0K | 0.00% | −7,000−77.6% | Reduced |
| Tower Research Capital LLC (TRC) | 2,097 | $68.0K | 0.00% | −5,242−71.4% | Reduced |
| Advisor Group Holdings, Inc. | 2,317 | $75.0K | 0.00% | +214+10.2% | Added |
| Nisa Investment Advisors, LLC | 2,616 | $84.0K | 0.00% | −1,235−32.1% | Reduced |
| Amundi | 3,017 | $97.0K | 0.00% | 00.0% | Unchanged |
| Virtus ETF Advisers LLC | 3,433 | $110.0K | 0.05% | −200−5.5% | Reduced |
| Great West Life Assurance Co | 3,874 | $132.0K | 0.00% | −588−13.2% | Reduced |
| Metropolitan Life Insurance Co | 5,579 | $179.5K | 0.01% | −18,510−76.8% | Reduced |
| D. E. Shaw & Co., Inc. | 6,248 | $201.0K | 0.00% | −988−13.7% | Reduced |
| Ergoteles LLC | 6,693 | $215.0K | 0.01% | +6,693 | New |
| Creative Planning | 6,780 | $218.0K | 0.00% | +1,572+30.2% | Added |
| Bridgewater Associates, LP | 6,867 | $221.0K | 0.00% | +6,867 | New |
| Gsa Capital Partners LLP | 6,940 | $223.0K | 0.03% | +1,106+19.0% | Added |
| Group One Trading, L.P. | 6,959 | $224.0K | 0.00% | −7,386−51.5% | Reduced |
| Ameritas Investment Partners, Inc. | 7,134 | $230.0K | 0.01% | 00.0% | Unchanged |
| Victory Capital Management Inc | 10,883 | $259.0K | 0.00% | −1,198−9.9% | Reduced |
| BNP Paribas Arbitrage, SA | 8,243 | $265.2K | 0.00% | −11,456−58.2% | Reduced |
| Royal Bank of Canada | 8,381 | $269.0K | 0.00% | −862−9.3% | Reduced |
| GAM Holding AG | 8,403 | $270.0K | 0.01% | 00.0% | Unchanged |
| E Fund Management Co., Ltd. | 8,827 | $284.0K | 0.01% | +8,827 | New |
| SG Americas Securities, LLC | 8,980 | $289.0K | 0.00% | −23,822−72.6% | Reduced |
| Brandywine Managers, LLC | 9,601 | $309.0K | 0.53% | 00.0% | Unchanged |
| SEI Investments Co | 10,518 | $328.0K | 0.00% | −834−7.3% | Reduced |
| Dana Investment Advisors, Inc. | 11,296 | $363.0K | 0.02% | +1,658+17.2% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 11,390 | $366.0K | 0.00% | +446+4.1% | Added |
| Utah Retirement Systems | 11,600 | $373.0K | 0.00% | 00.0% | Unchanged |
| Handelsbanken Fonder AB | 11,800 | $380.0K | 0.00% | −6,200−34.4% | Reduced |
| Public Employees Retirement Association of Colorado | 12,238 | $394.0K | 0.00% | 00.0% | Unchanged |
| Arthur M. Cohen & Associates, LLC | 12,416 | $399.0K | 0.08% | 00.0% | Unchanged |
| Capital Fund Management S.A. | 13,443 | $432.5K | 0.01% | −360−2.6% | Reduced |
| Stifel Financial Corp | 13,640 | $439.0K | 0.00% | −15−0.1% | Reduced |
| First Trust Advisors LP | 14,224 | $458.0K | 0.00% | −923−6.1% | Reduced |
| Profund Advisors LLC | 14,254 | $459.0K | 0.02% | −1,586−10.0% | Reduced |
| Virginia Retirement Systems Et Al | 14,600 | $470.0K | 0.00% | −11,100−43.2% | Reduced |
| Amalgamated Bank | 14,893 | $479.0K | 0.00% | −1,119−7.0% | Reduced |
| Amalgamated Financial Corp. | 14,893 | $479.0K | 0.00% | +14,893 | New |
| Algert Global LLC | 15,203 | $489.0K | 0.03% | +7,834+106.3% | Added |
| Engineers Gate Manager LP | 16,046 | $516.0K | 0.02% | +10,356+182.0% | Added |
| Cubist Systematic Strategies, LLC | 16,169 | $520.0K | 0.00% | +8,303+105.6% | Added |
| Teacher Retirement System of Texas | 16,488 | $530.0K | 0.00% | +919+5.9% | Added |
| Allianz Asset Management GmbH | 17,820 | $574.0K | 0.00% | −18,325−50.7% | Reduced |
| PDT Partners, LLC | 17,850 | $574.0K | 0.05% | +17,850 | New |
| Twinbeech Capital LP | 18,046 | $581.0K | 0.03% | +18,046 | New |
| Bartlett & Co. LLC | 18,510 | $595.0K | 0.01% | +1,567+9.2% | Added |
| Bartlett & Co. Wealth Management LLC | 18,510 | $595.5K | 0.01% | +1,567+9.2% | Added |
| Rockefeller Capital Management L.P. | 19,652 | $631.0K | 0.00% | +3,194+19.4% | Added |
| Ironwood Investment Management LLC | 19,842 | $638.0K | 0.35% | +459+2.4% | Added |
| Prudential Financial Inc | 20,753 | $667.0K | 0.00% | −195,048−90.4% | Reduced |
| Arizona State Retirement System | 21,458 | $690.0K | 0.01% | +178+0.8% | Added |
| AQR Capital Management LLC | 22,686 | $730.0K | 0.00% | −28,981−56.1% | Reduced |
| Mercer Global Advisors Inc | 22,915 | $737.0K | 0.00% | +5,563+32.1% | Added |
| Eaton Vance Management | 23,057 | $742.0K | 0.00% | +23,057 | New |
| Integral Health Asset Management, LLC | 26,000 | $836.0K | 0.22% | −74,000−74.0% | Reduced |
| Erste Asset Management GmbH | 26,900 | $871.6K | 0.02% | −3,700−12.1% | Reduced |
| AlphaCrest Capital Management LLC | 27,200 | $875.0K | 0.05% | +17,389+177.2% | Added |
| Parametric Portfolio Associates LLC | 27,557 | $887.0K | 0.00% | −4,887−15.1% | Reduced |
| Concentric Wealth Management, LLC | 27,967 | $900.0K | 0.26% | 00.0% | Unchanged |
| Walleye Capital LLC | 28,296 | $910.0K | 0.03% | +28,296 | New |
| Two Sigma Investments, LP | 30,001 | $965.0K | 0.00% | +21,425+249.8% | Added |
| State Board of Administration of Florida Retirement System | 30,468 | $980.0K | 0.00% | 00.0% | Unchanged |
| STRS Ohio | 30,900 | $994.0K | 0.00% | 00.0% | Unchanged |