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Denali Therapeutics Inc.

DNLI
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001714899

In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.

13F holders, Q3 2024

Institutional positions in Denali Therapeutics Inc. as of Sep 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
217
+16 vs. Q2 2024
Shares held
126.8M
+16.3M (+14.7%) vs. Q2 2024
Total value
$3.69B
+$1.13B (+43.9%) vs. Q2 2024
New holders
37
78 more added
Sold out
21
59 more reduced

2 institutions that held it in Q2 2024 haven't filed for Q3 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2024: 217 institutions
Q1 2021: 218 institutionsQ2 2021: 210 institutionsQ3 2021: 214 institutionsQ4 2021: 213 institutionsQ1 2022: 190 institutionsQ2 2022: 188 institutionsQ3 2022: 200 institutionsQ4 2022: 199 institutionsQ1 2023: 202 institutionsQ2 2023: 203 institutionsQ3 2023: 195 institutionsQ4 2023: 209 institutionsQ1 2024: 211 institutionsQ2 2024: 203 institutionsQ3 2024: 217 institutionsQ4 2024: 224 institutionsQ1 2025: 222 institutionsQ2 2025: 231 institutionsQ3 2025: 240 institutionsQ4 2025: 250 institutionsQ1 2026: 269 institutionsQ2 2026: 294 institutions
Value heldQ3 2024: $3.69B
Q1 2021: $4.60BQ2 2021: $6.32BQ3 2021: $4.28BQ4 2021: $3.80BQ1 2022: $2.79BQ2 2022: $2.73BQ3 2022: $2.84BQ4 2022: $2.94BQ1 2023: $2.49BQ2 2023: $3.18BQ3 2023: $2.24BQ4 2023: $2.47BQ1 2024: $2.51BQ2 2024: $2.88BQ3 2024: $3.69BQ4 2024: $2.61BQ1 2025: $1.85BQ2 2025: $1.93BQ3 2025: $1.97BQ4 2025: $2.50BQ1 2026: $2.82BQ2 2026: $4.00B
Institutions holding DNLI and their total value by quarter
QuarterHoldersValue
Q2 2026294$4.00B
Q1 2026269$2.82B
Q4 2025250$2.50B
Q3 2025240$1.97B
Q2 2025231$1.93B
Q1 2025222$1.85B
Q4 2024224$2.61B
Q3 2024217$3.69B
Q2 2024203$2.88B
Q1 2024211$2.51B
Q4 2023209$2.47B
Q3 2023195$2.24B
Q2 2023203$3.18B
Q1 2023202$2.49B
Q4 2022199$2.94B
Q3 2022200$2.84B
Q2 2022188$2.73B
Q1 2022190$2.79B
Q4 2021213$3.80B
Q3 2021214$4.28B
Q2 2021210$6.32B
Q1 2021218$4.60B

Institutions, Q3 2024

Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q2 2024.

Institutions holding DNLI in Q3 2024
InstitutionSharesValue% of portfolioChange in sharesAction
BlackRock, Inc.13,788,517$401.7M0.01%+13,788,517New
Baillie Gifford & Co13,345,887$388.8M0.29%−417,709−3.0%Reduced
Vanguard Group Inc11,177,234$325.6M0.01%−135,205−1.2%Reduced
Wellington Management Group LLP10,727,450$312.5M0.05%+903,683+9.2%Added
Capital Research Global Investors7,909,114$230.4M0.05%+782,581+11.0%Added
FMR LLC7,831,378$228.1M0.01%+7,596,508+3,234.3%Added
Temasek Holdings (Private) Ltd5,355,832$156.0M0.63%−350,513−6.1%Reduced
Crestline Management, LP4,460,732$129.9M7.40%−300,000−6.3%Reduced
State Street Corp4,252,011$123.9M0.01%−182,779−4.1%Reduced
UBS Asset Management Americas Inc3,749,486$109.2M0.03%+1,451,770+63.2%Added
Baker Bros. Advisors LP3,731,695$108.7M1.13%00.0%Unchanged
Alliancebernstein L.P.3,047,264$88.8M0.03%+1,028,730+51.0%Added
Geode Capital Management, LLC2,955,477$86.1M0.01%−27,061−0.9%Reduced
Price T Rowe Associates Inc2,869,795$83.6M0.01%+614,325+27.2%Added
Camber Capital Management LP2,000,000$58.3M2.26%00.0%Unchanged
Marshall Wace, LLP1,967,141$57.3M0.07%−451,692−18.7%Reduced
Morgan Stanley1,744,755$50.8M0.00%+520,877+42.6%Added
Dimensional Fund Advisors LP1,559,442$45.4M0.01%+141,970+10.0%Added
Goldman Sachs Group Inc1,367,821$39.8M0.01%+148,896+12.2%Added
Bank of New York Mellon Corp1,330,351$38.8M0.01%−209,920−13.6%Reduced
Principal Financial Group Inc1,238,476$36.1M0.02%+149,939+13.8%Added
Artisan Partners Limited Partnership1,091,018$31.8M0.05%−50,499−4.4%Reduced
Northern Trust Corp1,085,642$31.6M0.01%+2,683+0.2%Added
Charles Schwab Investment Management Inc1,015,810$29.6M0.01%−43,494−4.1%Reduced
Casdin Capital, LLC990,000$28.8M1.92%−310,000−23.8%Reduced
Candriam Luxembourg S.C.A.942,158$27.4M0.16%+215,659+29.7%Added
Siren, L.L.C.834,028$24.3M1.22%+834,028New
Citadel Advisors LLC777,280$22.6M0.02%−441,418−36.2%Reduced
Nuveen Asset Management, LLC715,300$20.8M0.01%−358,557−33.4%Reduced
Cercano Management LLC625,000$18.2M0.44%00.0%Unchanged
Yiheng Capital Management, L.P.600,098$17.5M3.23%−550,586−47.8%Reduced
Fisher Asset Management, LLC547,331$15.9M0.01%+69,223+14.5%Added
American Century Companies Inc451,374$13.1M0.01%−71,220−13.6%Reduced
Clarius Group, LLC409,995$11.9M0.84%00.0%Unchanged
Norges Bank397,539$11.6M0.00%−426,402−51.8%Reduced
Jane Street Group, LLC369,671$10.8M0.02%+138,307+59.8%Added
Standard Life Aberdeen plc363,679$10.6M0.02%−209,356−36.5%Reduced
Bank of America Corp348,164$10.1M0.00%−393,884−53.1%Reduced
Ensign Peak Advisors, Inc346,304$10.1M0.02%00.0%Unchanged
AXA S.A.344,883$10.0M0.03%+980.0%Added
Point72 Asset Management, L.P.333,530$9.72M0.03%−719,620−68.3%Reduced
StemPoint Capital LP282,050$8.22M2.46%+31,040+12.4%Added
Barclays PLC255,883$7.45M0.00%+128,823+101.4%Added
Swiss National Bank250,700$7.30M0.00%+17,900+7.7%Added
TD Asset Management Inc244,552$7.20M0.01%+65,400+36.5%Added
Deutsche Bank AG239,946$6.99M0.00%+16,546+7.4%Added
Wasatch Advisors Inc238,881$6.96M0.03%−163,528−40.6%Reduced
JPMorgan Chase & Co235,386$6.86M0.00%+14,324+6.5%Added
Teachers Retirement System of the State of Kentucky207,124$6.03M0.05%00.0%Unchanged
Manufacturers Life Insurance Company, The206,819$6.02M0.01%+34,538+20.0%Added
Invesco Ltd.206,363$6.01M0.00%+90,131+77.5%Added
Edmond de Rothschild Holding S.A.205,680$5.99M0.10%00.0%Unchanged
Rhumbline Advisers189,893$5.53M0.00%−4,966−2.5%Reduced
Pier Capital, LLC168,082$4.90M0.69%+2,596+1.6%Added
New York State Common Retirement Fund149,908$4.37M0.01%−14,037−8.6%Reduced
Cinctive Capital Management LP149,094$4.34M0.25%+36,771+32.7%Added
Legal & General Group Plc141,405$4.12M0.00%+12,059+9.3%Added
UBS Group AG141,403$4.12M0.00%+5,180+3.8%Added
Thrivent Financial for Lutherans138,862$4.04M0.01%+8,358+6.4%Added
Schroder Investment Management Group127,306$3.75M0.00%−218,067−63.1%Reduced
Fred Alger Management, LLC121,316$3.53M0.02%+94,302+349.1%Added
California State Teachers Retirement System121,112$3.53M0.00%+5,158+4.4%Added
Rafferty Asset Management, LLC117,681$3.43M0.01%−33,801−22.3%Reduced
Prudential Financial Inc117,393$3.42M0.00%+650+0.6%Added
Alps Advisors Inc106,247$3.09M0.02%−4,992−4.5%Reduced
ADAR1 Capital Management, LLC101,826$2.97M0.50%+63,826+168.0%Added
Two Sigma Investments, LP99,467$2.90M0.01%+4,600+4.8%Added
Holocene Advisors, LP97,447$2.84M0.01%+38,405+65.0%Added
Citigroup Inc94,714$2.76M0.00%+50,163+112.6%Added
Wells Fargo & Company93,697$2.73M0.00%+19,376+26.1%Added
Mirae Asset Global ETFs Holdings Ltd.81,664$2.38M0.01%+6,960+9.3%Added
State of Wisconsin Investment Board81,451$2.37M0.01%+4,520+5.9%Added
State of New Jersey Common Pension Fund D77,483$2.26M0.01%−25,613−24.8%Reduced
AIA Group Ltd74,815$2.18M0.06%+5,471+7.9%Added
Franklin Resources Inc80,041$2.15M0.00%+2,901+3.8%Added
MetLife Investment Management71,810$2.09M0.01%00.0%Unchanged
Northwest & Ethical Investments L.P.68,643$2.00M0.05%−7,192−9.5%Reduced
Nisa Investment Advisors, LLC66,482$1.94M0.01%+160+0.2%Added
Corebridge Financial, Inc.66,465$1.94M0.01%−410−0.6%Reduced
Nomura Asset Management Co Ltd65,033$1.89M0.01%+65,033New
Groupama Asset Managment78,045$1.83M0.05%+5,657+7.8%Added
Creative Planning60,254$1.76M0.00%+17,221+40.0%Added
Millennium Management LLC60,168$1.75M0.00%−559,761−90.3%Reduced
DekaBank Deutsche Girozentrale59,800$1.75M0.00%00.0%Unchanged
Pier 88 Investment Partners LLC59,170$1.72M0.38%−10,200−14.7%Reduced
Voya Investment Management LLC57,804$1.68M0.00%−976−1.7%Reduced
Janus Henderson Group PLC52,128$1.52M0.00%00.0%Unchanged
Susquehanna International Group, LLP50,170$1.46M0.00%−10,228−16.9%Reduced
Algert Global LLC48,630$1.42M0.04%+21,975+82.4%Added
Concentric Wealth Management, LLC46,526$1.36M0.33%00.0%Unchanged
Balyasny Asset Management LLC45,108$1.31M0.00%−75,504−62.6%Reduced
Employees Retirement System of Texas43,769$1.27M0.01%00.0%Unchanged
Skandinaviska Enskilda Banken AB (publ)43,245$1.26M0.01%00.0%Unchanged
Bank of Montreal42,259$1.24M0.00%+42,259New
Polar Asset Management Partners Inc.41,100$1.20M0.03%+17,000+70.5%Added
Victory Capital Management Inc39,900$1.16M0.00%+24,767+163.7%Added
Handelsbanken Fonder AB39,500$1.15M0.00%00.0%Unchanged
Knights of Columbus Asset Advisors LLC39,119$1.14M0.08%−18,876−32.5%Reduced
HighTower Advisors, LLC37,327$1.09M0.00%−587−1.5%Reduced
Arizona State Retirement System36,957$1.08M0.01%+3,843+11.6%Added