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Denali Therapeutics Inc.

DNLI
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001714899

In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.

13F holders, Q3 2024

Institutional positions in Denali Therapeutics Inc. as of Sep 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
217
+16 vs. Q2 2024
Shares held
126.8M
+16.3M (+14.7%) vs. Q2 2024
Total value
$3.69B
+$1.13B (+43.9%) vs. Q2 2024
New holders
37
78 more added
Sold out
21
59 more reduced

2 institutions that held it in Q2 2024 haven't filed for Q3 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2024: 217 institutions
Q1 2021: 218 institutionsQ2 2021: 210 institutionsQ3 2021: 214 institutionsQ4 2021: 213 institutionsQ1 2022: 190 institutionsQ2 2022: 188 institutionsQ3 2022: 200 institutionsQ4 2022: 199 institutionsQ1 2023: 202 institutionsQ2 2023: 203 institutionsQ3 2023: 195 institutionsQ4 2023: 209 institutionsQ1 2024: 211 institutionsQ2 2024: 203 institutionsQ3 2024: 217 institutionsQ4 2024: 224 institutionsQ1 2025: 222 institutionsQ2 2025: 231 institutionsQ3 2025: 240 institutionsQ4 2025: 250 institutionsQ1 2026: 269 institutionsQ2 2026: 294 institutions
Value heldQ3 2024: $3.69B
Q1 2021: $4.60BQ2 2021: $6.32BQ3 2021: $4.28BQ4 2021: $3.80BQ1 2022: $2.79BQ2 2022: $2.73BQ3 2022: $2.84BQ4 2022: $2.94BQ1 2023: $2.49BQ2 2023: $3.18BQ3 2023: $2.24BQ4 2023: $2.47BQ1 2024: $2.51BQ2 2024: $2.88BQ3 2024: $3.69BQ4 2024: $2.61BQ1 2025: $1.85BQ2 2025: $1.93BQ3 2025: $1.97BQ4 2025: $2.50BQ1 2026: $2.82BQ2 2026: $4.00B
Institutions holding DNLI and their total value by quarter
QuarterHoldersValue
Q2 2026294$4.00B
Q1 2026269$2.82B
Q4 2025250$2.50B
Q3 2025240$1.97B
Q2 2025231$1.93B
Q1 2025222$1.85B
Q4 2024224$2.61B
Q3 2024217$3.69B
Q2 2024203$2.88B
Q1 2024211$2.51B
Q4 2023209$2.47B
Q3 2023195$2.24B
Q2 2023203$3.18B
Q1 2023202$2.49B
Q4 2022199$2.94B
Q3 2022200$2.84B
Q2 2022188$2.73B
Q1 2022190$2.79B
Q4 2021213$3.80B
Q3 2021214$4.28B
Q2 2021210$6.32B
Q1 2021218$4.60B

Institutions, Q3 2024

Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q2 2024.

Institutions holding DNLI in Q3 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Ironwood Investment Management LLC36,584$1.07M0.52%+355+1.0%Added
Dana Investment Advisors, Inc.34,852$1.02M0.03%+583+1.7%Added
Hudson Bay Capital Management LP34,500$1.00M0.01%−140,500−80.3%Reduced
State Board of Administration of Florida Retirement System34,168$995.3K0.00%00.0%Unchanged
Squarepoint Ops LLC33,723$982.4K0.00%−89,957−72.7%Reduced
Teacher Retirement System of Texas32,191$938.0K0.00%+6,239+24.0%Added
ProShare Advisors LLC31,948$930.6K0.00%+7,150+28.8%Added
UBS Oconnor LLC30,744$895.6K0.02%−773−2.5%Reduced
Man Group plc30,427$886.3K0.00%−7,118−19.0%Reduced
BIT Capital GmbH29,762$867.0K0.08%−56,415−65.5%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)29,719$865.7K0.00%+3,316+12.6%Added
Intech Investment Management LLC29,543$860.6K0.01%+29,543New
Envestnet Asset Management Inc27,979$815.0K0.00%+6,838+32.3%Added
Los Angeles Capital Management LLC27,940$813.9K0.00%−24,923−47.1%Reduced
BNP Paribas Arbitrage, SA27,625$804.7K0.00%+19,259+230.2%Added
China Universal Asset Management Co., Ltd.27,535$802.1K0.09%+10,782+64.4%Added
Erste Asset Management GmbH26,900$791.7K0.01%00.0%Unchanged
HSBC Holdings PLC26,883$779.5K0.00%−2,759−9.3%Reduced
SEI Investments Co26,276$765.4K0.00%+3,606+15.9%Added
Profund Advisors LLC24,858$724.1K0.03%−4,515−15.4%Reduced
Trexquant Investment LP24,534$714.7K0.01%+24,534New
Cetera Investment Advisers22,297$649.5K0.00%+11,017+97.7%Added
Russell Investments Group, Ltd.21,974$640.1K0.00%−940−4.1%Reduced
Royal Bank of Canada21,931$639.0K0.00%+6,652+43.5%Added
NEOS Investment Management LLC21,648$630.6K0.02%00.0%Unchanged
Guggenheim Capital LLC20,613$600.5K0.00%+694+3.5%Added
ClariVest Asset Management LLC22,964$533.2K0.05%00.0%Unchanged
First Trust Advisors LP18,134$528.2K0.00%−1,116−5.8%Reduced
Options Solutions, LLC17,611$513.0K0.25%+17,611New
STRS Ohio17,400$506.9K0.00%00.0%Unchanged
HRT Financial LP16,943$493.0K0.00%+16,943New
Pictet Asset Management Holding SA16,550$482.1K0.00%+2,754+20.0%Added
AQR Capital Management LLC16,018$466.6K0.00%+16,018New
Cowen and Company, LLC15,800$460.3K0.02%+15,800New
Bellevue Group AG15,700$457.3K0.01%+15,700New
VELA Investment Management, LLC15,635$455.4K0.16%+15,635New
Y-Intercept (Hong Kong) Ltd13,823$402.7K0.02%−25,369−64.7%Reduced
Great West Life Assurance Co13,434$392.0K0.00%00.0%Unchanged
JustInvest LLC12,890$375.5K0.01%+2,100+19.5%Added
Ameritas Investment Partners, Inc.12,592$366.8K0.01%+362+3.0%Added
Public Employees Retirement Association of Colorado12,238$356.0K0.00%00.0%Unchanged
Graham Capital Management, L.P.11,765$342.7K0.01%+11,765New
Letko, Brosseau & Associates Inc11,350$330.6K0.01%00.0%Unchanged
Pitcairn Co11,259$328.0K0.02%+11,259New
Brevan Howard Capital Management LP11,161$325.1K0.02%−18,196−62.0%Reduced
nVerses Capital, LLC9,900$288.4K0.13%+9,900New
Stifel Financial Corp9,839$286.6K0.00%−3,008−23.4%Reduced
Integrated Advisors Network LLC9,710$282.9K0.01%+9,710New
MONECO Advisors, LLC9,100$265.1K0.03%+400+4.6%Added
Mackenzie Financial Corp8,256$240.5K0.00%+8,256New
Xponance, Inc.8,135$237.0K0.00%+8,135New
Bayesian Capital Management, LP8,000$233.0K0.03%−42,500−84.2%Reduced
Life Line Wealth Management LLC7,812$227.6K0.08%+7,812New
Breakwater Capital Group7,642$222.6K0.04%+7,642New
Colony Group, LLC7,597$221.3K0.00%+7,597New
E Fund Management Co., Ltd.7,561$220.3K0.01%−1,639−17.8%Reduced
Ameriprise Financial Inc7,400$215.6K0.00%+7,400New
Allspring Global Investments Holdings, LLC5,676$165.3K0.00%−421−6.9%Reduced
Mirae Asset Global Investments Co., Ltd.5,178$152.4K0.00%+920+21.6%Added
SG Americas Securities, LLC4,808$140.0K0.00%−9,000−65.2%Reduced
Amalgamated Bank4,192$122.0K0.00%00.0%Unchanged
Virtus ETF Advisers LLC4,164$121.3K0.06%+72+1.8%Added
Assetmark, Inc3,808$110.9K0.00%+580+18.0%Added
Point72 Asia (Singapore) Pte. Ltd.3,764$109.7K0.02%−4,571−54.8%Reduced
KBC Group NV3,603$105.0K0.00%00.0%Unchanged
Simplex Trading, LLC3,475$101.0K0.00%−1,459−29.6%Reduced
The PNC Financial Services Group, Inc.2,905$84.6K0.00%+536+22.6%Added
Acadian Asset Management LLC2,749$80.0K0.00%+2,749New
Quest Partners LLC2,512$73.2K0.01%+2,512New
GAMMA Investing LLC2,338$68.1K0.01%+281+13.7%Added
CWM, LLC2,153$63.0K0.00%+654+43.6%Added
Catalyst Funds Management Pty Ltd2,000$58.3K0.01%+2,000New
Group One Trading, L.P.1,691$49.3K0.00%+1,691New
Bartlett & Co. Wealth Management LLC1,500$43.7K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.1,297$37.8K0.00%+447+52.6%Added
US Bancorp1,168$34.0K0.00%−448−27.7%Reduced
Comerica Bank1,089$31.7K0.00%+674+162.4%Added
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.1,001$29.2K0.00%00.0%Unchanged
Smartleaf Asset Management LLC666$19.6K0.00%+190+39.9%Added
Covestor Ltd578$17.0K0.01%00.0%Unchanged
Signaturefd, LLC564$16.4K0.00%+30+5.6%Added
Daiwa Securities Group Inc.546$16.0K0.00%00.0%Unchanged
NBC Securities, Inc.532$15.0K0.00%00.0%Unchanged
Oarsman Capital, Inc.500$14.6K0.00%+500New
Nemes Rush Group LLC700$14.4K0.00%00.0%Unchanged
Huntington National Bank471$13.7K0.00%+26+5.8%Added
Tower Research Capital LLC (TRC)431$12.6K0.00%−20,401−97.9%Reduced
Umb Bank N A382$11.1K0.00%+382New
EverSource Wealth Advisors, LLC317$9.23K0.00%00.0%Unchanged
Lindbrook Capital, LLC283$8.24K0.00%+58+25.8%Added
Private Wealth Management Group, LLC260$7.57K0.00%00.0%Unchanged
Sterling Capital Management LLC257$7.49K0.00%+257New
City State Bank250$7.28K0.00%00.0%Unchanged
Versant Capital Management, Inc203$5.91K0.00%+102+101.0%Added
Meeder Asset Management Inc159$4.63K0.00%+159New
Massmutual Trust Co FSB154$4.49K0.00%00.0%Unchanged
Rothschild Investment LLC150$4.37K0.00%+90+150.0%Added
Activest Wealth Management131$3.82K0.00%00.0%Unchanged
SRS Capital Advisors, Inc.117$3.41K0.00%00.0%Unchanged
Parallel Advisors, LLC112$3.26K0.00%00.0%Unchanged