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Denali Therapeutics Inc.

DNLI
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001714899

In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.

13F holders, Q3 2024

Institutional positions in Denali Therapeutics Inc. as of Sep 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
217
+16 vs. Q2 2024
Shares held
126.8M
+16.3M (+14.7%) vs. Q2 2024
Total value
$3.69B
+$1.13B (+43.9%) vs. Q2 2024
New holders
37
78 more added
Sold out
21
59 more reduced

2 institutions that held it in Q2 2024 haven't filed for Q3 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2024: 217 institutions
Q1 2021: 218 institutionsQ2 2021: 210 institutionsQ3 2021: 214 institutionsQ4 2021: 213 institutionsQ1 2022: 190 institutionsQ2 2022: 188 institutionsQ3 2022: 200 institutionsQ4 2022: 199 institutionsQ1 2023: 202 institutionsQ2 2023: 203 institutionsQ3 2023: 195 institutionsQ4 2023: 209 institutionsQ1 2024: 211 institutionsQ2 2024: 203 institutionsQ3 2024: 217 institutionsQ4 2024: 224 institutionsQ1 2025: 222 institutionsQ2 2025: 231 institutionsQ3 2025: 240 institutionsQ4 2025: 250 institutionsQ1 2026: 269 institutionsQ2 2026: 294 institutions
Value heldQ3 2024: $3.69B
Q1 2021: $4.60BQ2 2021: $6.32BQ3 2021: $4.28BQ4 2021: $3.80BQ1 2022: $2.79BQ2 2022: $2.73BQ3 2022: $2.84BQ4 2022: $2.94BQ1 2023: $2.49BQ2 2023: $3.18BQ3 2023: $2.24BQ4 2023: $2.47BQ1 2024: $2.51BQ2 2024: $2.88BQ3 2024: $3.69BQ4 2024: $2.61BQ1 2025: $1.85BQ2 2025: $1.93BQ3 2025: $1.97BQ4 2025: $2.50BQ1 2026: $2.82BQ2 2026: $4.00B
Institutions holding DNLI and their total value by quarter
QuarterHoldersValue
Q2 2026294$4.00B
Q1 2026269$2.82B
Q4 2025250$2.50B
Q3 2025240$1.97B
Q2 2025231$1.93B
Q1 2025222$1.85B
Q4 2024224$2.61B
Q3 2024217$3.69B
Q2 2024203$2.88B
Q1 2024211$2.51B
Q4 2023209$2.47B
Q3 2023195$2.24B
Q2 2023203$3.18B
Q1 2023202$2.49B
Q4 2022199$2.94B
Q3 2022200$2.84B
Q2 2022188$2.73B
Q1 2022190$2.79B
Q4 2021213$3.80B
Q3 2021214$4.28B
Q2 2021210$6.32B
Q1 2021218$4.60B

Institutions, Q3 2024

Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q2 2024.

Institutions holding DNLI in Q3 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Avion Wealth25$00.00%00.0%Unchanged
Hemington Wealth Management3$00.00%+3New
Toronto Dominion Bank2$580.00%00.0%Unchanged
Global Retirement Partners, LLC3$870.00%−8−72.7%Reduced
Bokf, NA18$5080.00%+18New
Principal Securities, Inc.23$6700.00%−122−84.1%Reduced
First Horizon Advisors, Inc.25$7280.00%00.0%Unchanged
CVA Family Office, LLC30$8740.00%00.0%Unchanged
National Bank of Canada34$9900.00%+34New
AdvisorNet Financial, Inc40$1.17K0.00%+40New
Bell Investment Advisors, Inc52$1.51K0.00%00.0%Unchanged
Point72 (DIFC) Ltd55$1.61K0.00%+55New
Ronald Blue Trust, Inc.72$1.67K0.00%−10−12.2%Reduced
Capital Performance Advisors LLP63$1.83K0.00%+63New
Your Advocates Ltd., LLP100$2.91K0.00%00.0%Unchanged
Bessemer Group Inc110$3.00K0.00%+110New
Farther Finance Advisors, LLC107$3.13K0.00%+27+33.8%Added
Parallel Advisors, LLC112$3.26K0.00%00.0%Unchanged
SRS Capital Advisors, Inc.117$3.41K0.00%00.0%Unchanged
Activest Wealth Management131$3.82K0.00%00.0%Unchanged
Rothschild Investment LLC150$4.37K0.00%+90+150.0%Added
Massmutual Trust Co FSB154$4.49K0.00%00.0%Unchanged
Meeder Asset Management Inc159$4.63K0.00%+159New
Versant Capital Management, Inc203$5.91K0.00%+102+101.0%Added
City State Bank250$7.28K0.00%00.0%Unchanged
Sterling Capital Management LLC257$7.49K0.00%+257New
Private Wealth Management Group, LLC260$7.57K0.00%00.0%Unchanged
Lindbrook Capital, LLC283$8.24K0.00%+58+25.8%Added
EverSource Wealth Advisors, LLC317$9.23K0.00%00.0%Unchanged
Umb Bank N A382$11.1K0.00%+382New
Tower Research Capital LLC (TRC)431$12.6K0.00%−20,401−97.9%Reduced
Huntington National Bank471$13.7K0.00%+26+5.8%Added
Nemes Rush Group LLC700$14.4K0.00%00.0%Unchanged
Oarsman Capital, Inc.500$14.6K0.00%+500New
NBC Securities, Inc.532$15.0K0.00%00.0%Unchanged
Daiwa Securities Group Inc.546$16.0K0.00%00.0%Unchanged
Signaturefd, LLC564$16.4K0.00%+30+5.6%Added
Covestor Ltd578$17.0K0.01%00.0%Unchanged
Smartleaf Asset Management LLC666$19.6K0.00%+190+39.9%Added
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.1,001$29.2K0.00%00.0%Unchanged
Comerica Bank1,089$31.7K0.00%+674+162.4%Added
US Bancorp1,168$34.0K0.00%−448−27.7%Reduced
Advisor Group Holdings, Inc.1,297$37.8K0.00%+447+52.6%Added
Bartlett & Co. Wealth Management LLC1,500$43.7K0.00%00.0%Unchanged
Group One Trading, L.P.1,691$49.3K0.00%+1,691New
Catalyst Funds Management Pty Ltd2,000$58.3K0.01%+2,000New
CWM, LLC2,153$63.0K0.00%+654+43.6%Added
GAMMA Investing LLC2,338$68.1K0.01%+281+13.7%Added
Quest Partners LLC2,512$73.2K0.01%+2,512New
Acadian Asset Management LLC2,749$80.0K0.00%+2,749New
The PNC Financial Services Group, Inc.2,905$84.6K0.00%+536+22.6%Added
Simplex Trading, LLC3,475$101.0K0.00%−1,459−29.6%Reduced
KBC Group NV3,603$105.0K0.00%00.0%Unchanged
Point72 Asia (Singapore) Pte. Ltd.3,764$109.7K0.02%−4,571−54.8%Reduced
Assetmark, Inc3,808$110.9K0.00%+580+18.0%Added
Virtus ETF Advisers LLC4,164$121.3K0.06%+72+1.8%Added
Amalgamated Bank4,192$122.0K0.00%00.0%Unchanged
SG Americas Securities, LLC4,808$140.0K0.00%−9,000−65.2%Reduced
Mirae Asset Global Investments Co., Ltd.5,178$152.4K0.00%+920+21.6%Added
Allspring Global Investments Holdings, LLC5,676$165.3K0.00%−421−6.9%Reduced
Ameriprise Financial Inc7,400$215.6K0.00%+7,400New
E Fund Management Co., Ltd.7,561$220.3K0.01%−1,639−17.8%Reduced
Colony Group, LLC7,597$221.3K0.00%+7,597New
Breakwater Capital Group7,642$222.6K0.04%+7,642New
Life Line Wealth Management LLC7,812$227.6K0.08%+7,812New
Bayesian Capital Management, LP8,000$233.0K0.03%−42,500−84.2%Reduced
Xponance, Inc.8,135$237.0K0.00%+8,135New
Mackenzie Financial Corp8,256$240.5K0.00%+8,256New
MONECO Advisors, LLC9,100$265.1K0.03%+400+4.6%Added
Integrated Advisors Network LLC9,710$282.9K0.01%+9,710New
Stifel Financial Corp9,839$286.6K0.00%−3,008−23.4%Reduced
nVerses Capital, LLC9,900$288.4K0.13%+9,900New
Brevan Howard Capital Management LP11,161$325.1K0.02%−18,196−62.0%Reduced
Pitcairn Co11,259$328.0K0.02%+11,259New
Letko, Brosseau & Associates Inc11,350$330.6K0.01%00.0%Unchanged
Graham Capital Management, L.P.11,765$342.7K0.01%+11,765New
Public Employees Retirement Association of Colorado12,238$356.0K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.12,592$366.8K0.01%+362+3.0%Added
JustInvest LLC12,890$375.5K0.01%+2,100+19.5%Added
Great West Life Assurance Co13,434$392.0K0.00%00.0%Unchanged
Y-Intercept (Hong Kong) Ltd13,823$402.7K0.02%−25,369−64.7%Reduced
VELA Investment Management, LLC15,635$455.4K0.16%+15,635New
Bellevue Group AG15,700$457.3K0.01%+15,700New
Cowen and Company, LLC15,800$460.3K0.02%+15,800New
AQR Capital Management LLC16,018$466.6K0.00%+16,018New
Pictet Asset Management Holding SA16,550$482.1K0.00%+2,754+20.0%Added
HRT Financial LP16,943$493.0K0.00%+16,943New
STRS Ohio17,400$506.9K0.00%00.0%Unchanged
Options Solutions, LLC17,611$513.0K0.25%+17,611New
First Trust Advisors LP18,134$528.2K0.00%−1,116−5.8%Reduced
ClariVest Asset Management LLC22,964$533.2K0.05%00.0%Unchanged
Guggenheim Capital LLC20,613$600.5K0.00%+694+3.5%Added
NEOS Investment Management LLC21,648$630.6K0.02%00.0%Unchanged
Royal Bank of Canada21,931$639.0K0.00%+6,652+43.5%Added
Russell Investments Group, Ltd.21,974$640.1K0.00%−940−4.1%Reduced
Cetera Investment Advisers22,297$649.5K0.00%+11,017+97.7%Added
Trexquant Investment LP24,534$714.7K0.01%+24,534New
Profund Advisors LLC24,858$724.1K0.03%−4,515−15.4%Reduced
SEI Investments Co26,276$765.4K0.00%+3,606+15.9%Added
HSBC Holdings PLC26,883$779.5K0.00%−2,759−9.3%Reduced