Skip to main content

Denali Therapeutics Inc.

DNLI
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001714899

In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.

13F holders, Q2 2021

Institutional positions in Denali Therapeutics Inc. as of Jun 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
210
−7 vs. Q1 2021
Shares held
80.6M
+149.8K (+0.2%) vs. Q1 2021
Total value
$6.32B
+$1.72B (+37.5%) vs. Q1 2021
New holders
34
81 more added
Sold out
41
59 more reduced

1 institution that held it in Q1 2021 haven't filed for Q2 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2021: 210 institutions
Q1 2021: 218 institutionsQ2 2021: 210 institutionsQ3 2021: 214 institutionsQ4 2021: 213 institutionsQ1 2022: 190 institutionsQ2 2022: 188 institutionsQ3 2022: 200 institutionsQ4 2022: 199 institutionsQ1 2023: 202 institutionsQ2 2023: 203 institutionsQ3 2023: 195 institutionsQ4 2023: 209 institutionsQ1 2024: 211 institutionsQ2 2024: 203 institutionsQ3 2024: 217 institutionsQ4 2024: 224 institutionsQ1 2025: 222 institutionsQ2 2025: 231 institutionsQ3 2025: 240 institutionsQ4 2025: 250 institutionsQ1 2026: 269 institutionsQ2 2026: 294 institutions
Value heldQ2 2021: $6.32B
Q1 2021: $4.60BQ2 2021: $6.32BQ3 2021: $4.28BQ4 2021: $3.80BQ1 2022: $2.79BQ2 2022: $2.73BQ3 2022: $2.84BQ4 2022: $2.94BQ1 2023: $2.49BQ2 2023: $3.18BQ3 2023: $2.24BQ4 2023: $2.47BQ1 2024: $2.51BQ2 2024: $2.88BQ3 2024: $3.69BQ4 2024: $2.61BQ1 2025: $1.85BQ2 2025: $1.93BQ3 2025: $1.97BQ4 2025: $2.50BQ1 2026: $2.82BQ2 2026: $4.00B
Institutions holding DNLI and their total value by quarter
QuarterHoldersValue
Q2 2026294$4.00B
Q1 2026269$2.82B
Q4 2025250$2.50B
Q3 2025240$1.97B
Q2 2025231$1.93B
Q1 2025222$1.85B
Q4 2024224$2.61B
Q3 2024217$3.69B
Q2 2024203$2.88B
Q1 2024211$2.51B
Q4 2023209$2.47B
Q3 2023195$2.24B
Q2 2023203$3.18B
Q1 2023202$2.49B
Q4 2022199$2.94B
Q3 2022200$2.84B
Q2 2022188$2.73B
Q1 2022190$2.79B
Q4 2021213$3.80B
Q3 2021214$4.28B
Q2 2021210$6.32B
Q1 2021218$4.60B

Institutions, Q2 2021

Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q1 2021.

Institutions holding DNLI in Q2 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Baillie Gifford & Co15,147,613$1.19B0.58%+2,152,416+16.6%Added
Crestline Management, LP8,135,481$638.1M55.19%−1,849,355−18.5%Reduced
Vanguard Group Inc7,644,130$599.6M0.01%−522,320−6.4%Reduced
BlackRock Inc.7,036,041$551.9M0.02%+471,589+7.2%Added
Price T Rowe Associates Inc4,903,452$384.6M0.04%−1,154,827−19.1%Reduced
Temasek Holdings (Private) Ltd4,410,457$346.0M1.16%00.0%Unchanged
Gilder Gagnon Howe & Co LLC2,835,733$222.4M1.09%−168,820−5.6%Reduced
Flagship Pioneering Inc.2,730,263$214.2M2.74%00.0%Unchanged
FMR LLC2,669,083$209.4M0.02%−18,617−0.7%Reduced
State Street Corp2,320,460$182.0M0.01%+303,793+15.1%Added
Credit Suisse AG1,966,508$154.3M0.12%+8,515+0.4%Added
Casdin Capital, LLC1,610,000$126.3M3.21%00.0%Unchanged
Geode Capital Management, LLC1,517,021$119.0M0.02%+264,189+21.1%Added
Bamco Inc1,255,224$98.5M0.23%+45,400+3.8%Added
Northern Trust Corp979,058$76.8M0.01%+225,424+29.9%Added
Norges Bank741,980$58.2M0.01%+144,214+24.1%Added
Marshall Wace, LLP645,999$50.7M0.27%+546,481+549.1%Added
Charles Schwab Investment Management Inc640,234$50.2M0.02%+74,718+13.2%Added
Goldman Sachs Group Inc587,818$46.1M0.01%−60,033−9.3%Reduced
Artisan Partners Limited Partnership566,845$44.5M0.05%+979+0.2%Added
Wasatch Advisors Inc537,246$42.1M0.17%+58,804+12.3%Added
Artal Group S.A.500,000$39.2M0.89%00.0%Unchanged
Pictet Asset Management Ltd491,372$38.5M0.04%+2,873+0.6%Added
Two Sigma Advisers, LP464,100$36.4M0.10%+12,800+2.8%Added
Morgan Stanley431,032$33.8M0.00%−31,128−6.7%Reduced
UBS Asset Management Americas Inc429,871$33.7M0.01%+131,587+44.1%Added
Nuveen Asset Management, LLC384,060$30.1M0.01%+106,439+38.3%Added
Invesco Ltd.383,565$30.1M0.01%+356,912+1,339.1%Added
Jennison Associates LLC374,512$29.4M0.02%00.0%Unchanged
Bank of New York Mellon Corp347,369$27.2M0.01%+86,005+32.9%Added
Mitsubishi UFJ Trust & Banking Corp345,300$27.1M0.06%−21,540−5.9%Reduced
Principal Financial Group Inc329,344$25.8M0.02%−8,223−2.4%Reduced
Dimensional Fund Advisors LP325,348$25.5M0.01%−95,854−22.8%Reduced
Euclidean Capital LLC323,749$25.4M8.24%00.0%Unchanged
American Century Companies Inc292,847$23.0M0.02%+1,605+0.6%Added
Eagle Asset Management Inc291,103$22.8M0.10%−26,759−8.4%Reduced
Prudential Financial Inc220,014$17.3M0.02%+32,070+17.1%Added
Two Sigma Investments, LP219,415$17.2M0.05%−277,288−55.8%Reduced
Natixis209,698$16.4M0.07%+70,000+50.1%Added
California Public Employees Retirement System198,661$15.6M0.01%+35,329+21.6%Added
AXA S.A.182,700$14.3M0.04%+5,722+3.2%Added
New York State Common Retirement Fund180,261$14.1M0.01%+33,358+22.7%Added
Teachers Retirement System of the State of Kentucky174,796$13.7M0.13%+36,500+26.4%Added
Swiss National Bank171,800$13.5M0.01%−6,300−3.5%Reduced
Alliancebernstein L.P.155,360$12.2M0.00%+58,760+60.8%Added
Tekla Capital Management LLC150,086$11.8M0.38%00.0%Unchanged
Wells Fargo & Company147,773$11.6M0.00%+31,649+27.3%Added
Federated Hermes, Inc.138,632$10.9M0.02%+8,672+6.7%Added
California State Teachers Retirement System125,379$9.84M0.01%+30,553+32.2%Added
State of Wisconsin Investment Board122,700$9.63M0.02%+33,000+36.8%Added
Deutsche Bank AG117,038$9.18M0.00%+58,249+99.1%Added
Balyasny Asset Management LLC101,934$8.00M0.04%+33,832+49.7%Added
Lisanti Capital Growth, LLC98,130$7.70M0.95%+98,130New
Rhumbline Advisers94,855$7.44M0.01%+23,280+32.5%Added
JGP Global Gestao de Recursos Ltda.91,760$7.20M2.43%+91,760New
JPMorgan Chase & Co90,880$7.13M0.00%+15,699+20.9%Added
Baker Bros. Advisors LP88,738$6.96M0.03%00.0%Unchanged
Avidity Partners Management LP86,100$6.75M0.18%+86,100New
D. E. Shaw & Co., Inc.83,585$6.56M0.01%−122,577−59.5%Reduced
TD Asset Management Inc126,837$6.47M0.01%−14,000−9.9%Reduced
Integral Health Asset Management, LLC81,000$6.35M1.75%−16,000−16.5%Reduced
AQR Capital Management LLC79,284$6.22M0.01%−7,340−8.5%Reduced
Edmond de Rothschild Holding S.A.77,200$6.06M0.14%+20,200+35.4%Added
ClariVest Asset Management LLC75,245$5.90M0.20%+58,039+337.3%Added
Putnam Investments LLC71,718$5.63M0.01%+98+0.1%Added
AIA Group Ltd81,891$5.30M0.36%+27,516+50.6%Added
Citigroup Inc65,247$5.12M0.00%−4,527−6.5%Reduced
Sectoral Asset Management Inc65,000$5.10M0.41%+61,000+1,525.0%Added
Parametric Portfolio Associates LLC64,209$5.04M0.00%+20,390+46.5%Added
Candriam Luxembourg S.C.A.63,781$5.00M0.03%+63,781New
Bank of America Corp63,752$5.00M0.00%+11,981+23.1%Added
Russell Investments Group, Ltd.63,757$4.99M0.01%+15,791+32.9%Added
Legal & General Group Plc62,244$4.88M0.00%+18,694+42.9%Added
First Trust Advisors LP61,318$4.81M0.01%+17,547+40.1%Added
Soros Capital Management LLC54,000$4.24M0.54%+54,000New
DekaBank Deutsche Girozentrale52,900$4.03M0.01%+15,000+39.6%Added
Manufacturers Life Insurance Company, The51,333$4.03M0.00%+15,287+42.4%Added
American International Group, Inc.50,980$4.00M0.02%+12,457+32.3%Added
State of New Jersey Common Pension Fund D50,860$3.99M0.01%+1,589+3.2%Added
Polar Capital Holdings Plc48,798$3.83M0.02%+48,798New
ProShare Advisors LLC45,362$3.56M0.01%+11,785+35.1%Added
Stenahm Asset Managment Ltd45,000$3.53M2.16%+45,000New
Victory Capital Management Inc42,121$3.30M0.00%+3,766+9.8%Added
Ensign Peak Advisors, Inc41,942$3.29M0.01%+300+0.7%Added
Macquarie Group Ltd41,910$3.29M0.00%−1,022−2.4%Reduced
Mark Asset Management LP38,839$3.05M0.45%−73,080−65.3%Reduced
Voya Investment Management LLC35,765$2.81M0.01%+8,192+29.7%Added
Rafferty Asset Management, LLC34,780$2.73M0.02%−16,725−32.5%Reduced
Los Angeles Capital Management LLC33,432$2.62M0.01%+16,457+96.9%Added
MetLife Investment Management32,389$2.54M0.02%+7,625+30.8%Added
STRS Ohio31,200$2.45M0.01%+4,600+17.3%Added
Platinum Investment Management Ltd30,791$2.42M0.06%00.0%Unchanged
Erste Asset Management GmbH30,600$2.35M0.05%00.0%Unchanged
Skandinaviska Enskilda Banken AB (publ)29,785$2.34M0.01%+3,685+14.1%Added
State Board of Administration of Florida Retirement System29,419$2.31M0.00%+5,604+23.5%Added
Castleark Management LLC29,040$2.28M0.08%+29,040New
Acadian Asset Management LLC26,754$2.10M0.01%+20,817+350.6%Added
Metropolitan Life Insurance Co24,797$1.95M0.03%+7,680+44.9%Added
Barclays PLC23,761$1.86M0.00%−66,012−73.5%Reduced
Allianz Asset Management GmbH23,455$1.84M0.00%00.0%Unchanged