Denali Therapeutics Inc.
DNLI- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.
13F holders, Q1 2023
Institutional positions in Denali Therapeutics Inc. as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 202
- +4 vs. Q4 2022
- Shares held
- 108.0M
- +2.13M (+2.0%) vs. Q4 2022
- Total value
- $2.49B
- −$456.7M (−15.5%) vs. Q4 2022
- New holders
- 26
- 92 more added
- Sold out
- 22
- 51 more reduced
1 institution that held it in Q4 2022 haven't filed for Q1 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 294 | $4.00B |
| Q1 2026 | 269 | $2.82B |
| Q4 2025 | 250 | $2.50B |
| Q3 2025 | 240 | $1.97B |
| Q2 2025 | 231 | $1.93B |
| Q1 2025 | 222 | $1.85B |
| Q4 2024 | 224 | $2.61B |
| Q3 2024 | 217 | $3.69B |
| Q2 2024 | 203 | $2.88B |
| Q1 2024 | 211 | $2.51B |
| Q4 2023 | 209 | $2.47B |
| Q3 2023 | 195 | $2.24B |
| Q2 2023 | 203 | $3.18B |
| Q1 2023 | 202 | $2.49B |
| Q4 2022 | 199 | $2.94B |
| Q3 2022 | 200 | $2.84B |
| Q2 2022 | 188 | $2.73B |
| Q1 2022 | 190 | $2.79B |
| Q4 2021 | 213 | $3.80B |
| Q3 2021 | 214 | $4.28B |
| Q2 2021 | 210 | $6.32B |
| Q1 2021 | 218 | $4.60B |
Institutions, Q1 2023
Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q4 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Baillie Gifford & Co | 15,352,111 | $353.7M | 0.32% | +232,637+1.5% | Added |
| Vanguard Group Inc | 10,118,493 | $233.1M | 0.01% | +171,395+1.7% | Added |
| BlackRock Inc. | 9,474,397 | $218.3M | 0.01% | +152,383+1.6% | Added |
| Temasek Holdings (Private) Ltd | 6,895,992 | $158.9M | 0.94% | +379,951+5.8% | Added |
| Crestline Management, LP | 6,410,732 | $147.7M | 18.05% | −450,000−6.6% | Reduced |
| Wellington Management Group LLP | 5,200,460 | $119.8M | 0.02% | +78,730+1.5% | Added |
| State Street Corp | 4,591,389 | $105.8M | 0.01% | −254,421−5.3% | Reduced |
| Price T Rowe Associates Inc | 3,537,778 | $81.5M | 0.01% | −111,110−3.0% | Reduced |
| Flagship Pioneering Inc. | 2,619,968 | $60.4M | 2.35% | 00.0% | Unchanged |
| ARCH Venture Management, LLC | 2,568,749 | $59.2M | 28.57% | −1,100,000−30.0% | Reduced |
| Capital Research Global Investors | 2,468,824 | $56.9M | 0.02% | +208,182+9.2% | Added |
| Geode Capital Management, LLC | 2,146,172 | $49.4M | 0.01% | +96,215+4.7% | Added |
| Bank of New York Mellon Corp | 2,016,623 | $46.5M | 0.01% | +10,703+0.5% | Added |
| Gilder Gagnon Howe & Co LLC | 1,656,397 | $38.2M | 0.63% | −110,745−6.3% | Reduced |
| Credit Suisse AG | 1,553,472 | $35.8M | 0.04% | +20,089+1.3% | Added |
| Citadel Advisors LLC | 1,374,325 | $31.7M | 0.03% | +1,339,712+3,870.5% | Added |
| Casdin Capital, LLC | 1,300,000 | $30.0M | 2.47% | 00.0% | Unchanged |
| Pictet Asset Management SA | 1,248,490 | $28.8M | 0.04% | +77,134+6.6% | Added |
| FMR LLC | 1,093,564 | $25.2M | 0.00% | −1,120,230−50.6% | Reduced |
| Baker Bros. Advisors LP | 1,088,738 | $25.1M | 0.14% | 00.0% | Unchanged |
| Federated Hermes, Inc. | 1,063,500 | $24.5M | 0.06% | +288,500+37.2% | Added |
| Northern Trust Corp | 1,018,004 | $23.5M | 0.00% | +33,813+3.4% | Added |
| Yiheng Capital Management, L.P. | 1,014,684 | $23.4M | 1.82% | 00.0% | Unchanged |
| Norges Bank | 969,440 | $22.3M | 0.00% | −54,766−5.3% | Reduced |
| Charles Schwab Investment Management Inc | 836,328 | $19.3M | 0.01% | −3450.0% | Reduced |
| Artal Group S.A. | 802,899 | $18.5M | 1.10% | +2,899+0.4% | Added |
| Barclays PLC | 656,427 | $15.1M | 0.02% | +70,462+12.0% | Added |
| T. Rowe Price Investment Management, Inc. | 647,013 | $14.9M | 0.01% | +13,655+2.2% | Added |
| Dimensional Fund Advisors LP | 627,325 | $14.4M | 0.00% | +69,067+12.4% | Added |
| Cercano Management LLC | 625,000 | $14.4M | 0.57% | 00.0% | Unchanged |
| Deerfield Management Company, L.P. (Series C) | 594,989 | $13.7M | 0.31% | −205,011−25.6% | Reduced |
| Goldman Sachs Group Inc | 572,843 | $13.2M | 0.00% | −198,609−25.7% | Reduced |
| Morgan Stanley | 569,122 | $13.1M | 0.00% | +136,636+31.6% | Added |
| UBS Asset Management Americas Inc | 567,141 | $13.1M | 0.01% | +23,218+4.3% | Added |
| Wasatch Advisors Inc | 558,167 | $12.9M | 0.08% | +107,217+23.8% | Added |
| Polar Capital Holdings Plc | 505,000 | $11.6M | 0.09% | +505,000 | New |
| Principal Financial Group Inc | 488,961 | $11.3M | 0.01% | −37,498−7.1% | Reduced |
| American Century Companies Inc | 473,783 | $10.9M | 0.01% | +1,495+0.3% | Added |
| Artisan Partners Limited Partnership | 423,665 | $9.76M | 0.02% | −12,008−2.8% | Reduced |
| Bank of America Corp | 419,836 | $9.67M | 0.00% | +85,064+25.4% | Added |
| Renaissance Technologies LLC | 408,100 | $9.40M | 0.01% | +158,500+63.5% | Added |
| Millennium Management LLC | 386,289 | $8.90M | 0.01% | +89,196+30.0% | Added |
| Nuveen Asset Management, LLC | 360,636 | $8.31M | 0.00% | −15,111−4.0% | Reduced |
| Marshall Wace, LLP | 350,539 | $8.08M | 0.02% | −610,100−63.5% | Reduced |
| Susquehanna International Group, LLP | 340,564 | $7.85M | 0.01% | +317,311+1,364.6% | Added |
| Candriam Luxembourg S.C.A. | 357,878 | $7.59M | 0.05% | 00.0% | Unchanged |
| Tekla Capital Management LLC | 324,829 | $7.48M | 0.28% | +52,309+19.2% | Added |
| Eventide Asset Management, LLC | 313,407 | $7.22M | 0.13% | +313,407 | New |
| Skandinaviska Enskilda Banken AB (publ) | 306,970 | $7.07M | 0.05% | −2,122−0.7% | Reduced |
| Mitsubishi UFJ Trust & Banking Corp | 304,630 | $7.02M | 0.02% | +2,760+0.9% | Added |
| Eagle Asset Management Inc | 302,961 | $6.98M | 0.04% | −26,123−7.9% | Reduced |
| Clarius Group, LLC | 290,330 | $6.69M | 0.57% | +29,726+11.4% | Added |
| AXA S.A. | 289,242 | $6.66M | 0.02% | −678−0.2% | Reduced |
| Jefferies Financial Group Inc. | 263,123 | $6.06M | 0.13% | +263,123 | New |
| Rafferty Asset Management, LLC | 256,973 | $5.92M | 0.04% | −26,769−9.4% | Reduced |
| Sectoral Asset Management Inc | 244,850 | $5.64M | 1.08% | +1,000+0.4% | Added |
| Squarepoint Ops LLC | 235,662 | $5.43M | 0.04% | +235,662 | New |
| Walleye Trading LLC | 226,753 | $5.22M | 0.19% | +226,753 | New |
| Teachers Retirement System of the State of Kentucky | 221,500 | $5.10M | 0.05% | +15,000+7.3% | Added |
| Citigroup Inc | 208,340 | $4.80M | 0.01% | +80,220+62.6% | Added |
| Swiss National Bank | 205,200 | $4.73M | 0.00% | −3,300−1.6% | Reduced |
| Voya Investment Management LLC | 191,728 | $4.42M | 0.00% | +21,854+12.9% | Added |
| California Public Employees Retirement System | 176,131 | $4.06M | 0.00% | −17,430−9.0% | Reduced |
| Alliancebernstein L.P. | 170,160 | $3.92M | 0.00% | +15,200+9.8% | Added |
| Twinbeech Capital LP | 149,302 | $3.44M | 0.07% | +149,302 | New |
| Rhumbline Advisers | 146,142 | $3.37M | 0.00% | +3,210+2.2% | Added |
| JPMorgan Chase & Co | 145,987 | $3.36M | 0.00% | −37,989−20.6% | Reduced |
| Ensign Peak Advisors, Inc | 144,547 | $3.33M | 0.01% | +2,000+1.4% | Added |
| BNP Paribas Arbitrage, SA | 138,072 | $3.18M | 0.01% | +80,384+139.3% | Added |
| New York State Common Retirement Fund | 134,894 | $3.11M | 0.00% | −16,060−10.6% | Reduced |
| Deutsche Bank AG | 130,729 | $3.01M | 0.00% | +19,999+18.1% | Added |
| UBS Group AG | 127,351 | $2.93M | 0.00% | +7,170+6.0% | Added |
| Wells Fargo & Company | 125,070 | $2.88M | 0.00% | +60,381+93.3% | Added |
| California State Teachers Retirement System | 124,012 | $2.86M | 0.00% | +5,431+4.6% | Added |
| Two Sigma Advisers, LP | 117,900 | $2.72M | 0.01% | −33,900−22.3% | Reduced |
| Jane Street Group, LLC | 115,805 | $2.67M | 0.00% | +100,836+673.6% | Added |
| Manufacturers Life Insurance Company, The | 115,183 | $2.65M | 0.00% | +3,124+2.8% | Added |
| Woodline Partners LP | 100,311 | $2.31M | 0.03% | +100,311 | New |
| Edmond de Rothschild Holding S.A. | 99,880 | $2.30M | 0.05% | 00.0% | Unchanged |
| Legal & General Group Plc | 97,618 | $2.25M | 0.00% | +2,603+2.7% | Added |
| Jump Financial, LLC | 93,371 | $2.15M | 0.09% | +93,371 | New |
| Northwest & Ethical Investments L.P. | 92,497 | $2.13M | 0.07% | −2,366−2.5% | Reduced |
| Cubist Systematic Strategies, LLC | 91,806 | $2.12M | 0.02% | +86,966+1,796.8% | Added |
| Susquehanna Fundamental Investments, LLC | 91,249 | $2.10M | 0.05% | 00.0% | Unchanged |
| Alps Advisors Inc | 90,045 | $2.07M | 0.02% | −1,984−2.2% | Reduced |
| TD Asset Management Inc | 88,322 | $2.03M | 0.00% | −10,887−11.0% | Reduced |
| TCW Group Inc | 88,311 | $2.03M | 0.03% | +49,280+126.3% | Added |
| State of Wisconsin Investment Board | 87,826 | $2.02M | 0.01% | +1,260+1.5% | Added |
| International Biotechnology Trust PLC | 86,575 | $1.99M | 0.56% | +48,575+127.8% | Added |
| Invesco Ltd. | 82,937 | $1.91M | 0.00% | −5,802−6.5% | Reduced |
| Russell Investments Group, Ltd. | 82,295 | $1.90M | 0.00% | −17,078−17.2% | Reduced |
| Trexquant Investment LP | 80,524 | $1.86M | 0.05% | +57,669+252.3% | Added |
| State of New Jersey Common Pension Fund D | 78,253 | $1.80M | 0.01% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 75,741 | $1.75M | 0.01% | +1,306+1.8% | Added |
| Mirae Asset Global Investments Co., Ltd. | 66,978 | $1.54M | 0.00% | +12,371+22.7% | Added |
| DekaBank Deutsche Girozentrale | 59,800 | $1.32M | 0.00% | 00.0% | Unchanged |
| MetLife Investment Management | 57,027 | $1.31M | 0.01% | 00.0% | Unchanged |
| Engineers Gate Manager LP | 56,785 | $1.31M | 0.05% | +56,785 | New |
| Guggenheim Capital LLC | 56,244 | $1.30M | 0.01% | −8,447−13.1% | Reduced |
| Platinum Investment Management Ltd | 55,341 | $1.28M | 0.04% | 00.0% | Unchanged |