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Denali Therapeutics Inc.

DNLI
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001714899

In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.

13F holders, Q1 2023

Institutional positions in Denali Therapeutics Inc. as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
202
+4 vs. Q4 2022
Shares held
108.0M
+2.13M (+2.0%) vs. Q4 2022
Total value
$2.49B
−$456.7M (−15.5%) vs. Q4 2022
New holders
26
92 more added
Sold out
22
51 more reduced

1 institution that held it in Q4 2022 haven't filed for Q1 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2023: 202 institutions
Q1 2021: 218 institutionsQ2 2021: 210 institutionsQ3 2021: 214 institutionsQ4 2021: 213 institutionsQ1 2022: 190 institutionsQ2 2022: 188 institutionsQ3 2022: 200 institutionsQ4 2022: 199 institutionsQ1 2023: 202 institutionsQ2 2023: 203 institutionsQ3 2023: 195 institutionsQ4 2023: 209 institutionsQ1 2024: 211 institutionsQ2 2024: 203 institutionsQ3 2024: 217 institutionsQ4 2024: 224 institutionsQ1 2025: 222 institutionsQ2 2025: 231 institutionsQ3 2025: 240 institutionsQ4 2025: 250 institutionsQ1 2026: 269 institutionsQ2 2026: 294 institutions
Value heldQ1 2023: $2.49B
Q1 2021: $4.60BQ2 2021: $6.32BQ3 2021: $4.28BQ4 2021: $3.80BQ1 2022: $2.79BQ2 2022: $2.73BQ3 2022: $2.84BQ4 2022: $2.94BQ1 2023: $2.49BQ2 2023: $3.18BQ3 2023: $2.24BQ4 2023: $2.47BQ1 2024: $2.51BQ2 2024: $2.88BQ3 2024: $3.69BQ4 2024: $2.61BQ1 2025: $1.85BQ2 2025: $1.93BQ3 2025: $1.97BQ4 2025: $2.50BQ1 2026: $2.82BQ2 2026: $4.00B
Institutions holding DNLI and their total value by quarter
QuarterHoldersValue
Q2 2026294$4.00B
Q1 2026269$2.82B
Q4 2025250$2.50B
Q3 2025240$1.97B
Q2 2025231$1.93B
Q1 2025222$1.85B
Q4 2024224$2.61B
Q3 2024217$3.69B
Q2 2024203$2.88B
Q1 2024211$2.51B
Q4 2023209$2.47B
Q3 2023195$2.24B
Q2 2023203$3.18B
Q1 2023202$2.49B
Q4 2022199$2.94B
Q3 2022200$2.84B
Q2 2022188$2.73B
Q1 2022190$2.79B
Q4 2021213$3.80B
Q3 2021214$4.28B
Q2 2021210$6.32B
Q1 2021218$4.60B

Institutions, Q1 2023

Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q4 2022.

Institutions holding DNLI in Q1 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Ronald Blue Trust, Inc.7$00.00%−1−12.5%Reduced
Toronto Dominion Bank2$00.00%+2New
Baldrige Asset Management LLC11$00.00%+11New
Global Retirement Partners, LLC3$780.00%00.0%Unchanged
Allworth Financial LP8$1850.00%00.0%Unchanged
Institutional & Family Asset Management, LLC11$2530.00%00.0%Unchanged
Parallel Advisors, LLC31$7140.00%+31New
Bell Investment Advisors, Inc64$1.48K0.00%00.0%Unchanged
Your Advocates Ltd., LLP100$2.30K0.00%00.0%Unchanged
Ameritas Advisory Services, LLC100$2.30K0.00%+100New
Activest Wealth Management131$2.87K0.00%00.0%Unchanged
Signaturefd, LLC221$5.09K0.00%+126+132.6%Added
First Horizon Advisors, Inc.231$5.32K0.00%+16+7.4%Added
City State Bank250$6.00K0.00%00.0%Unchanged
CWM, LLC269$6.00K0.00%+209+348.3%Added
Itau Unibanco Holding S.A.268$6.17K0.00%00.0%Unchanged
Advisory Services Network, LLC300$6.91K0.00%00.0%Unchanged
Covestor Ltd293$7.00K0.01%+91+45.0%Added
Umb Bank N A306$7.05K0.00%00.0%Unchanged
Belpointe Asset Management LLC374$8.62K0.00%00.0%Unchanged
Lindbrook Capital, LLC454$10.5K0.00%+99+27.9%Added
Huntington National Bank457$10.5K0.00%+116+34.0%Added
Cutler Group LP600$13.0K0.00%−1,650−73.3%Reduced
Daiwa Securities Group Inc.546$13.0K0.00%00.0%Unchanged
US Bancorp656$15.1K0.00%+199+43.5%Added
Assetmark, Inc772$17.8K0.00%+198+34.5%Added
The PNC Financial Services Group, Inc.1,456$33.5K0.00%−213−12.8%Reduced
China Universal Asset Management Co., Ltd.1,851$42.6K0.01%+471+34.1%Added
Advisor Group Holdings, Inc.2,318$53.4K0.00%+98+4.4%Added
Lazard Asset Management LLC2,920$67.0K0.00%−2,433−45.5%Reduced
Virtus ETF Advisers LLC3,293$75.9K0.04%−1,259−27.7%Reduced
Aquatic Capital Management LLC3,800$88.0K0.01%+3,800New
Tower Research Capital LLC (TRC)4,005$92.0K0.00%+2,451+157.7%Added
Great West Life Assurance Co4,642$107.0K0.00%00.0%Unchanged
Allspring Global Investments Holdings, LLC5,608$129.2K0.00%+2,366+73.0%Added
Metropolitan Life Insurance Co6,037$139.1K0.01%−688−10.2%Reduced
Simplex Trading, LLC6,293$144.0K0.01%+4,911+355.4%Added
Rockefeller Capital Management L.P.8,724$200.0K0.00%−1,134−11.5%Reduced
Ameritas Investment Partners, Inc.8,709$200.7K0.01%00.0%Unchanged
Fox Run Management, L.L.C.8,917$205.4K0.07%+8,917New
Campbell & CO Investment Adviser LLC9,005$207.5K0.04%+9,005New
Royal Bank of Canada9,087$209.0K0.00%−10,134−52.7%Reduced
AQR Capital Management LLC9,201$212.0K0.00%+9,201New
Brandywine Managers, LLC9,601$221.2K0.16%00.0%Unchanged
Voloridge Investment Management, LLC9,705$223.6K0.00%−11,782−54.8%Reduced
Creative Planning10,348$238.4K0.00%+2,879+38.5%Added
Cetera Advisor Networks LLC10,373$239.0K0.00%+10,373New
Point72 Middle East FZE10,848$249.9K0.01%+7,255+201.9%Added
Allianz Asset Management GmbH11,300$260.4K0.00%00.0%Unchanged
Prelude Capital Management, LLC11,339$261.3K0.02%+3,996+54.4%Added
Raymond James & Associates11,407$262.8K0.00%+1,490+15.0%Added
Dynamic Technology Lab Private Ltd11,423$263.0K0.02%+11,423New
Victory Capital Management Inc11,718$270.0K0.00%−1,538−11.6%Reduced
Verition Fund Management LLC11,782$271.5K0.00%+11,782New
Public Employees Retirement Association of Colorado12,238$282.0K0.00%00.0%Unchanged
Public Employees Retirement System of Ohio12,271$283.0K0.00%+6,020+96.3%Added
Prudential Financial Inc9,180$286.8K0.00%−6−0.1%Reduced
HSBC Holdings PLC13,553$310.6K0.00%+4,204+45.0%Added
Stifel Financial Corp13,527$311.7K0.00%+120+0.9%Added
Virginia Retirement Systems Et Al13,700$315.6K0.00%+1,000+7.9%Added
Handelsbanken Fonder AB14,100$325.0K0.00%00.0%Unchanged
E Fund Management Co., Ltd.14,619$337.0K0.02%−242−1.6%Reduced
Am Investment Strategies LLC15,031$346.0K0.12%+15,031New
Cerity Partners LLC15,127$348.5K0.00%+15,127New
Amalgamated Bank15,380$354.0K0.00%−2,579−14.4%Reduced
Algert Global LLC16,097$370.9K0.02%−13,329−45.3%Reduced
SEI Investments Co16,368$377.1K0.00%+3,667+28.9%Added
Zurcher Kantonalbank (Zurich Cantonalbank)16,818$387.5K0.00%+4,500+36.5%Added
Arthur M. Cohen & Associates, LLC17,479$402.7K0.11%+2,141+14.0%Added
Nisa Investment Advisors, LLC17,758$409.0K0.00%−160−0.9%Reduced
Los Angeles Capital Management LLC18,507$426.4K0.00%−2,395−11.5%Reduced
Ironwood Investment Management LLC18,796$433.1K0.27%−353−1.8%Reduced
Linden Thomas Advisory Services, LLC19,225$443.0K0.11%+961+5.3%Added
VELA Investment Management, LLC20,672$476.3K0.22%+6,926+50.4%Added
Bartlett & Co. LLC21,540$496.0K0.01%+760+3.7%Added
Bartlett & Co. Wealth Management LLC21,540$496.3K0.01%+760+3.7%Added
STRS Ohio21,900$504.0K0.00%−11,800−35.0%Reduced
ProShare Advisors LLC22,286$513.5K0.00%−4,622−17.2%Reduced
ExodusPoint Capital Management, LP24,907$574.0K0.01%+24,907New
Erste Asset Management GmbH26,900$589.4K0.01%00.0%Unchanged
Mercer Global Advisors Inc26,299$606.0K0.00%−731−2.7%Reduced
Dana Investment Advisors, Inc.26,799$617.4K0.03%+1,683+6.7%Added
Arizona State Retirement System27,546$634.7K0.01%+3,182+13.1%Added
Occudo Quantitative Strategies LP29,221$673.3K0.06%+29,221New
Teacher Retirement System of Texas29,287$675.0K0.00%+3,138+12.0%Added
Bellevue Group AG31,000$714.2K0.01%00.0%Unchanged
State Board of Administration of Florida Retirement System32,288$743.9K0.00%00.0%Unchanged
Concentric Wealth Management, LLC36,486$840.6K0.28%+8,519+30.5%Added
SG Americas Securities, LLC37,291$859.0K0.01%+32,745+720.3%Added
Ergoteles LLC37,491$863.8K0.03%+37,491New
Envestnet Asset Management Inc41,437$954.7K0.00%+520+1.3%Added
Janus Henderson Group PLC42,168$972.2K0.00%+26,279+165.4%Added
Pier 88 Investment Partners LLC42,840$987.0K0.24%+7,600+21.6%Added
D. E. Shaw & Co., Inc.44,336$1.02M0.00%−90,091−67.0%Reduced
Profund Advisors LLC48,827$1.12M0.07%+33,960+228.4%Added
ClariVest Asset Management LLC49,267$1.14M0.05%+39+0.1%Added
Group One Trading, L.P.49,760$1.15M0.05%+49,760New
AIA Group Ltd50,264$1.16M0.06%+27,502+120.8%Added
Bamco Inc50,500$1.16M0.00%−213,756−80.9%Reduced
HighTower Advisors, LLC51,704$1.19M0.00%+29,495+132.8%Added