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Denali Therapeutics Inc.

DNLI
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001714899

In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.

13F holders, Q1 2021

Institutional positions in Denali Therapeutics Inc. as of Mar 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
218
No complete 13F data for Q4 2020
Shares held
80.5M
No complete 13F data for Q4 2020
Total value
$4.60B
No complete 13F data for Q4 2020

Holders and value by quarter

Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2021: 218 institutions
Q1 2021: 218 institutionsQ2 2021: 210 institutionsQ3 2021: 214 institutionsQ4 2021: 213 institutionsQ1 2022: 190 institutionsQ2 2022: 188 institutionsQ3 2022: 200 institutionsQ4 2022: 199 institutionsQ1 2023: 202 institutionsQ2 2023: 203 institutionsQ3 2023: 195 institutionsQ4 2023: 209 institutionsQ1 2024: 211 institutionsQ2 2024: 203 institutionsQ3 2024: 217 institutionsQ4 2024: 224 institutionsQ1 2025: 222 institutionsQ2 2025: 231 institutionsQ3 2025: 240 institutionsQ4 2025: 250 institutionsQ1 2026: 269 institutionsQ2 2026: 294 institutions
Value heldQ1 2021: $4.60B
Q1 2021: $4.60BQ2 2021: $6.32BQ3 2021: $4.28BQ4 2021: $3.80BQ1 2022: $2.79BQ2 2022: $2.73BQ3 2022: $2.84BQ4 2022: $2.94BQ1 2023: $2.49BQ2 2023: $3.18BQ3 2023: $2.24BQ4 2023: $2.47BQ1 2024: $2.51BQ2 2024: $2.88BQ3 2024: $3.69BQ4 2024: $2.61BQ1 2025: $1.85BQ2 2025: $1.93BQ3 2025: $1.97BQ4 2025: $2.50BQ1 2026: $2.82BQ2 2026: $4.00B
Institutions holding DNLI and their total value by quarter
QuarterHoldersValue
Q2 2026294$4.00B
Q1 2026269$2.82B
Q4 2025250$2.50B
Q3 2025240$1.97B
Q2 2025231$1.93B
Q1 2025222$1.85B
Q4 2024224$2.61B
Q3 2024217$3.69B
Q2 2024203$2.88B
Q1 2024211$2.51B
Q4 2023209$2.47B
Q3 2023195$2.24B
Q2 2023203$3.18B
Q1 2023202$2.49B
Q4 2022199$2.94B
Q3 2022200$2.84B
Q2 2022188$2.73B
Q1 2022190$2.79B
Q4 2021213$3.80B
Q3 2021214$4.28B
Q2 2021210$6.32B
Q1 2021218$4.60B

Institutions, Q1 2021

Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc..

Livermore's 13F data starts with Q1 2021, so Q1 2021 has no change from the previous quarter.

Institutions holding DNLI in Q1 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Baillie Gifford & Co12,995,197$742.0M0.42%––
Crestline Management, LP9,984,836$570.1M73.16%––
Vanguard Group Inc8,166,450$466.3M0.01%––
BlackRock Inc.6,564,452$374.8M0.01%––
Price T Rowe Associates Inc6,058,279$345.9M0.03%––
Temasek Holdings (Private) Ltd4,410,457$251.8M0.99%––
Gilder Gagnon Howe & Co LLC3,004,553$171.6M0.92%––
Flagship Pioneering Inc.2,730,263$155.9M2.50%––
FMR LLC2,687,700$153.5M0.01%––
State Street Corp2,016,667$115.2M0.01%––
Credit Suisse AG1,957,993$111.8M0.08%––
Casdin Capital, LLC1,610,000$91.9M2.74%––
Geode Capital Management, LLC1,252,832$71.5M0.01%––
Bamco Inc1,209,824$69.1M0.17%––
Northern Trust Corp753,634$43.0M0.01%––
Goldman Sachs Group Inc647,851$37.0M0.01%––
Norges Bank597,766$34.1M0.01%––
Artisan Partners Limited Partnership565,866$32.3M0.04%––
Charles Schwab Investment Management Inc565,516$32.3M0.01%––
Artal Group S.A.500,000$28.6M0.60%––
Two Sigma Investments, LP496,703$28.4M0.09%––
Pictet Asset Management Ltd488,499$27.9M0.03%––
Wasatch Advisors Inc478,442$27.3M0.12%––
Morgan Stanley462,160$26.4M0.00%––
Two Sigma Advisers, LP451,300$25.8M0.07%––
Dimensional Fund Advisors LP421,202$24.0M0.01%––
Jennison Associates LLC374,512$21.4M0.02%––
Mitsubishi UFJ Trust & Banking Corp366,840$20.9M0.05%––
Principal Financial Group Inc337,567$19.3M0.01%––
Euclidean Capital LLC323,749$18.5M6.19%––
Eagle Asset Management Inc317,862$17.8M0.08%––
UBS Asset Management Americas Inc298,284$17.0M0.01%––
American Century Companies Inc291,242$16.6M0.01%––
Nuveen Asset Management, LLC277,621$15.9M0.01%––
Marshall Wace North America L.P.275,926$15.8M0.07%––
Renaissance Technologies LLC265,900$15.2M0.02%––
Bank of New York Mellon Corp261,364$14.9M0.00%––
Citadel Advisors LLC240,784$13.7M0.01%––
Caas Capital Management LP232,796$13.3M0.40%––
D. E. Shaw & Co., Inc.206,162$11.8M0.01%––
Prudential Financial Inc187,944$10.7M0.02%––
Swiss National Bank178,100$10.2M0.01%––
AXA S.A.176,978$10.1M0.03%––
California Public Employees Retirement System163,332$9.33M0.01%––
Tekla Capital Management LLC150,086$8.57M0.29%––
New York State Common Retirement Fund146,903$8.39M0.01%––
TD Asset Management Inc140,837$8.04M0.01%––
Natixis139,698$7.98M0.03%––
Teachers Retirement System of the State of Kentucky138,296$7.90M0.08%––
Federated Hermes, Inc.129,960$7.42M0.01%––
Wells Fargo & Company116,124$6.63M0.00%––
Mark Asset Management LP111,919$6.39M1.01%––
Marshall Wace, LLP99,518$5.68M0.03%––
Hamilton Lane Advisors LLC97,370$5.56M1.81%––
Integral Health Asset Management, LLC97,000$5.54M1.58%––
Alliancebernstein L.P.96,600$5.52M0.00%––
California State Teachers Retirement System94,826$5.42M0.01%––
Barclays PLC89,773$5.13M0.00%––
State of Wisconsin Investment Board89,700$5.12M0.01%––
Baker Bros. Advisors LP88,738$5.07M0.02%––
AQR Capital Management LLC86,624$4.95M0.01%––
Arrowstreet Capital, Limited Partnership85,607$4.89M0.01%––
Cubist Systematic Strategies, LLC83,641$4.78M0.06%––
JPMorgan Chase & Co75,181$4.29M0.00%––
Putnam Investments LLC71,620$4.09M0.01%––
Rhumbline Advisers71,575$4.09M0.01%––
Citigroup Inc69,774$3.98M0.00%––
Balyasny Asset Management LLC68,102$3.89M0.02%––
Deutsche Bank AG58,789$3.36M0.00%––
Man Group plc58,525$3.34M0.01%––
Edmond de Rothschild Holding S.A.57,000$3.25M0.09%––
AIA Group Ltd54,375$3.10M0.45%––
Capital Fund Management S.A.52,319$2.99M0.10%––
Bank of America Corp51,771$2.96M0.00%––
Rafferty Asset Management, LLC51,505$2.94M0.02%––
State of New Jersey Common Pension Fund D49,271$2.81M0.01%––
Russell Investments Group, Ltd.47,966$2.73M0.00%––
Jacobs Levy Equity Management, Inc45,296$2.59M0.02%––
Parametric Portfolio Associates LLC43,819$2.50M0.00%––
First Trust Advisors LP43,771$2.50M0.00%––
Legal & General Group Plc43,550$2.49M0.00%––
Macquarie Group Ltd42,932$2.45M0.00%––
Ensign Peak Advisors, Inc41,642$2.38M0.01%––
Tudor Investment Corp Et Al39,106$2.23M0.05%––
American International Group, Inc.38,523$2.20M0.01%––
Victory Capital Management Inc38,355$2.19M0.00%––
Connor, Clark & Lunn Investment Management Ltd.37,906$2.16M0.01%––
DekaBank Deutsche Girozentrale37,900$2.08M0.01%––
Manufacturers Life Insurance Company, The36,046$2.06M0.00%––
Royal Bank of Canada35,981$2.06M0.00%––
ProShare Advisors LLC33,577$1.92M0.01%––
Platinum Investment Management Ltd30,791$1.76M0.04%––
UBS Group AG30,229$1.73M0.00%––
Erste Asset Management GmbH30,600$1.66M0.04%––
Voloridge Investment Management, LLC27,958$1.60M0.01%––
Voya Investment Management LLC27,573$1.57M0.00%––
SG Americas Securities, LLC27,178$1.55M0.01%––
Parallax Volatility Advisers, L.P.26,777$1.53M0.01%––
Invesco Ltd.26,653$1.52M0.00%––
STRS Ohio26,600$1.52M0.01%––