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Denali Therapeutics Inc.

DNLI
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001714899

In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 295 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.

Four kinds of short-selling data, each measuring something different:

  • Short interest: shares sold short and not yet bought back, as of a settlement date. FINRA publishes it twice a month, about eight business days after the settlement date.
  • Daily short volume: shares sold short each day in off-exchange trades reported to FINRA. It counts trades, not open positions, and is published the next day.
  • Fails-to-deliver: shares not delivered by the settlement date. The SEC publishes them twice a month, about two weeks late.
  • ATS (dark pool) volume: weekly volume on alternative trading systems and other off-exchange venues. FINRA publishes it two to four weeks after the week.

More in the glossary.

Short interest

Shares sold short and not yet bought back, from FINRA, on every settlement date in the last two years.

Short interest
14.7M
Shares, settlement Oct 30, 2026
Change
−780.4K
−5.0% vs. Oct 15, 2026
Days to cover
9.91
Short interest ÷ average daily volume
Average daily volume
1.48M
Shares, as reported by FINRA
Short interest by settlement date
Oct 31, 2024: 7,427,916 sharesNov 15, 2024: 7,098,359 sharesNov 29, 2024: 7,374,155 sharesDec 13, 2024: 7,464,110 sharesDec 31, 2024: 7,838,984 sharesJan 15, 2025: 7,968,985 sharesJan 31, 2025: 7,736,705 sharesFeb 14, 2025: 8,685,245 sharesFeb 28, 2025: 8,893,475 sharesMar 14, 2025: 10,505,627 sharesMar 31, 2025: 11,444,098 sharesApr 15, 2025: 13,003,125 sharesApr 30, 2025: 11,742,268 sharesMay 15, 2025: 12,102,577 sharesMay 30, 2025: 12,224,894 sharesJun 13, 2025: 11,947,808 sharesJun 30, 2025: 12,457,321 sharesJul 15, 2025: 12,682,664 sharesJul 31, 2025: 12,830,063 sharesAug 15, 2025: 13,471,070 sharesAug 29, 2025: 13,746,176 sharesSep 15, 2025: 13,079,532 sharesSep 30, 2025: 14,150,041 sharesOct 15, 2025: 14,527,782 sharesOct 31, 2025: 13,110,288 sharesNov 14, 2025: 14,017,386 sharesNov 28, 2025: 12,977,218 sharesDec 15, 2025: 13,092,563 sharesDec 31, 2025: 14,560,677 sharesJan 15, 2026: 14,858,586 sharesJan 30, 2026: 13,558,718 sharesFeb 13, 2026: 13,594,971 sharesFeb 27, 2026: 14,319,419 sharesMar 13, 2026: 14,258,580 sharesMar 31, 2026: 15,421,152 sharesApr 15, 2026: 15,284,401 sharesApr 30, 2026: 14,813,936 sharesMay 15, 2026: 14,026,925 sharesMay 29, 2026: 14,990,471 sharesJun 15, 2026: 15,407,744 sharesJun 30, 2026: 15,949,089 sharesJul 15, 2026: 16,035,916 sharesJul 31, 2026: 17,434,654 sharesAug 14, 2026: 17,959,465 sharesAug 31, 2026: 16,642,362 sharesSep 15, 2026: 17,139,415 sharesSep 30, 2026: 15,463,975 sharesOct 15, 2026: 15,475,322 sharesOct 30, 2026: 14,694,882 shares
Short interest in DNLI by settlement date
Settlement dateShort interestChangeChange %Avg. daily volumeDays to cover
Oct 30, 202614.7M−780.4K−5.0%1.48M9.91
Oct 15, 202615.5M+11.3K+0.1%1.92M8.07
Sep 30, 202615.5M−1.68M−9.8%2.02M7.64
Sep 15, 202617.1M+497.1K+3.0%1.43M11.97
Aug 31, 202616.6M−1.32M−7.3%951.2K17.50
Aug 14, 202618.0M+524.8K+3.0%1.45M12.41
Jul 31, 202617.4M+1.40M+8.7%1.44M12.12
Jul 15, 202616.0M+86.8K+0.5%1.91M8.39
Jun 30, 202615.9M+541.3K+3.5%2.30M6.95
Jun 15, 202615.4M+417.3K+2.8%1.83M8.43
May 29, 202615.0M+963.5K+6.9%1.87M8.02
May 15, 202614.0M−787.0K−5.3%1.87M7.51
Apr 30, 202614.8M−470.5K−3.1%1.49M9.95
Apr 15, 202615.3M−136.8K−0.9%1.38M11.04
Mar 31, 202615.4M+1.16M+8.2%2.31M6.67
Mar 13, 202614.3M−60.8K−0.4%1.50M9.53
Feb 27, 202614.3M+724.4K+5.3%1.59M9.03
Feb 13, 202613.6M+36.3K+0.3%1.56M8.71
Jan 30, 202613.6M−1.30M−8.8%1.93M7.02
Jan 15, 202614.9M+297.9K+2.1%1.54M9.68
Dec 31, 202514.6M+1.47M+11.2%1.17M12.46
Dec 15, 202513.1M+115.3K+0.9%2.13M6.15
Nov 28, 202513.0M−1.04M−7.4%1.29M10.05
Nov 14, 202514.0M+907.1K+6.9%1.55M9.06
Oct 31, 202513.1M−1.42M−9.8%1.48M8.85
Oct 15, 202514.5M+377.7K+2.7%1.71M8.52
Sep 30, 202514.2M+1.07M+8.2%2.49M5.69
Sep 15, 202513.1M−666.6K−4.9%2.36M5.54
Aug 29, 202513.7M+275.1K+2.0%1.62M8.49
Aug 15, 202513.5M+641.0K+5.0%1.91M7.04
Jul 31, 202512.8M+147.4K+1.2%1.52M8.44
Jul 15, 202512.7M+225.3K+1.8%1.34M9.45
Jun 30, 202512.5M+509.5K+4.3%1.58M7.86
Jun 13, 202511.9M−277.1K−2.3%1.85M6.46
May 30, 202512.2M+122.3K+1.0%1.25M9.75
May 15, 202512.1M+360.3K+3.1%1.32M9.15
Apr 30, 202511.7M−1.26M−9.7%1.42M8.29
Apr 15, 202513.0M+1.56M+13.6%1.98M6.56
Mar 31, 202511.4M+938.5K+8.9%1.12M10.25
Mar 14, 202510.5M+1.61M+18.1%1.67M6.30
Feb 28, 20258.89M+208.2K+2.4%935.6K9.51
Feb 14, 20258.69M+948.5K+12.3%868.3K10.00
Jan 31, 20257.74M−232.3K−2.9%899.8K8.60
Jan 15, 20257.97M+130.0K+1.7%1.17M6.83
Dec 31, 20247.84M+374.9K+5.0%1.08M7.26
Dec 13, 20247.46M+90.0K+1.2%616.6K12.10
Nov 29, 20247.37M+275.8K+3.9%1.02M7.25
Nov 15, 20247.10M−329.6K−4.4%889.6K7.98
Oct 31, 20247.43M−305.5K−4.0%628.8K11.81

Fails-to-deliver

Shares that weren't delivered by the settlement date, from the SEC, for the last 30 dates with fails. The price is the previous day's closing price published by the SEC.

Fails-to-deliver in DNLI by settlement date
Settlement dateSharesPriceValue
Sep 10, 202639,910$21.57$860.9K
Sep 8, 2026676$22.28$15.1K
Sep 4, 20265,459$22.80$124.5K
Sep 3, 20268,776$22.85$200.5K
Aug 25, 2026400$24.20$9.68K
Aug 24, 20263,095$24.92$77.1K
Aug 21, 20263,852$24.95$96.1K
Aug 18, 202631$24.35$754.85
Aug 7, 20264,921$24.73$121.7K
Jul 16, 202640$23.02$920.8
Jul 13, 202692$25.68$2.36K
Jul 2, 2026439$25.98$11.4K
Jul 1, 202660$25.72$1.54K
Jun 30, 2026191$25.89$4.94K
Jun 26, 202628$24.73$692.44
Jun 24, 20267,431$24.77$184.1K
Jun 22, 2026315$23.31$7.34K
Jun 15, 2026106$21.66$2.30K
Jun 11, 202649$20.61$1.01K
Jun 10, 2026184$20.79$3.83K
Jun 8, 202630,328$19.52$592.0K
Jun 3, 20261,327$19.35$25.7K
Jun 2, 20262,722$20.41$55.6K
May 27, 2026179,418$19.38$3.48M
May 18, 2026217$18.62$4.04K
May 8, 20268$19.71$157.68
May 4, 2026411$18.30$7.52K
Apr 30, 202612$18.60$223.2
Apr 16, 20261$21.68$21.68
Apr 15, 202659$20.16$1.19K

Daily short volume

Off-exchange short-sale volume, not short interest: shares sold short each day in trades reported to FINRA, for the last 30 trading days.

The short volume ratio isn't a sentiment gauge: market makers sell short to fill buy orders and to hedge, so short sales are usually about half of off-exchange volume.

Off-exchange short volume in DNLI by trade date
Trade dateShort volumeShort exemptOff-exchange volumeShort volume ratio
Nov 10, 2026190,1850367,44851.8%
Nov 9, 2026218,2490554,55139.4%
Nov 6, 2026314,4053592,74253.0%
Nov 5, 2026317,0167811,87739.0%
Nov 4, 2026519,0007,9021,548,40933.5%
Nov 3, 2026296,143747860,06134.4%
Nov 2, 2026250,713168480,87652.1%
Oct 30, 2026392,8811547,24871.8%
Oct 29, 2026123,4270527,46323.4%
Oct 28, 2026140,0705706,46119.8%
Oct 27, 2026173,7960575,91730.2%
Oct 26, 202679,95032190,71341.9%
Oct 23, 2026125,0570257,04548.7%
Oct 22, 2026120,6870226,40553.3%
Oct 21, 2026168,8600527,27332.0%
Oct 20, 2026393,0268,000761,38551.6%
Oct 19, 2026456,6780934,50948.9%
Oct 16, 2026423,0240763,20355.4%
Oct 15, 2026189,1400471,99640.1%
Oct 14, 2026307,5541001,244,26824.7%
Oct 13, 2026363,9160755,38048.2%
Oct 12, 2026279,0690526,94653.0%
Oct 9, 2026210,85522475,90444.3%
Oct 8, 2026251,4691495,34350.8%
Oct 7, 2026248,4032,766458,56654.2%
Oct 6, 2026912,1249981,188,70976.7%
Oct 5, 2026309,9700549,82656.4%
Oct 2, 2026256,8220613,11941.9%
Oct 1, 2026389,3040652,46059.7%
Sep 30, 2026367,4880647,00456.8%

ATS (dark pool) volume

Weekly volume on alternative trading systems (ATS) and other off-exchange (OTC) venues, from FINRA, for the last 12 weeks. ATS share is ATS volume ÷ (ATS + OTC volume), not a share of all trading.

Weekly ATS and OTC volume in DNLI
Week ofTierATS sharesATS tradesOther OTC sharesOther OTC tradesATS share
Oct 5, 2026T22,037,50139,8441,851,9339,82652.4%
Sep 28, 2026T22,606,34546,3981,536,48610,51662.9%
Sep 21, 2026T23,048,69851,6601,286,19814,26070.3%
Sep 14, 2026T22,026,22644,6451,249,80114,12361.9%
Sep 7, 2026T21,643,83634,085667,0806,73771.1%
Aug 31, 2026T21,766,54631,489856,3316,86567.4%
Aug 24, 2026T21,258,34830,975553,0606,67269.5%
Aug 17, 2026T21,115,29234,462688,1236,87161.8%
Aug 10, 2026T21,954,99139,987690,56712,28573.9%
Aug 3, 2026T21,722,21840,240865,6028,24766.6%
Jul 27, 2026T21,970,64335,6971,142,0286,21063.3%
Jul 20, 2026T21,516,05232,765621,9966,69270.9%