Denali Therapeutics Inc.

DNLI

Exchange: Nasdaq
Industry: Biological Products, (No Diagnostic Substances)
SEC CIK: 0001714899

SEC filings (opens in a new tab)

In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.

Q4 2023 vs. Q3 2023

How the institutions holding Denali Therapeutics Inc. changed between Q3 2023 and Q4 2023.

All holders in Q4 2023 All holders in Q3 2023

13F holders of DNLI: Q3 2023 compared with Q4 2023
Measure	Q3 2023	Of which not filed for Q4 2023	Q4 2023	Change
Holders	195	2	209	+16
Shares	108.6M	165.6K	115.0M	+6.57M (+6.1%)
Value	$2.24B	$3.41M	$2.47B	+$224.9M (+10.0%)

2 institutions that held it in Q3 2023 haven't filed for Q4 2023 yet. Not filing isn't selling, so the changes leave them out.

New holders (37)

Institutions that held Denali Therapeutics Inc. at the end of Q4 2023 but not at the end of Q3 2023.

Institutions new to DNLI in Q4 2023
Institution	Shares	Value	% of portfolio
Takeda Pharmaceutical Co Ltd	4,214,559	$86.9M	26.55%
Marshall Wace, LLP	1,667,397	$35.8M	0.07%
Point72 Asset Management, L.P.	644,406	$13.8M	0.04%
Braidwell LP	461,769	$9.91M	0.36%
Standard Life Aberdeen plc	324,829	$6.97M	0.02%
Balyasny Asset Management LLC	260,587	$5.59M	0.02%
Hudson Bay Capital Management LP	175,000	$3.76M	0.03%
Schroder Investment Management Group	154,000	$3.30M	0.00%
Neuberger Berman Group LLC	144,461	$3.10M	0.00%
Soleus Capital Management, L.P.	130,000	$2.79M	0.31%
Seven Eight Capital, LP	72,587	$1.56M	0.18%
Pathway Capital Management, LP	69,450	$1.49M	1.67%
Twinbeech Capital LP	40,580	$870.8K	0.01%
Groupama Asset Managment	35,013	$751.6K	0.02%
PDT Partners, LLC	32,900	$706.0K	0.08%
University of Texas/Texas Am Investment Managment Co	30,428	$653.0K	0.18%
Thrivent Financial for Lutherans	29,682	$637.0K	0.00%
Two Sigma Investments, LP	28,376	$608.9K	0.00%
Landscape Capital Management, L.L.C.	24,318	$521.9K	0.05%
Employees Retirement System of Texas	21,375	$459.0K	0.01%
Schonfeld Strategic Advisors LLC	18,327	$393.3K	0.00%
Walleye Capital LLC	16,728	$359.0K	0.01%
Virtu Financial LLC	15,576	$334.0K	0.03%
Quest Partners LLC	9,965	$213.8K	0.05%
Brandywine Managers, LLC	9,601	$206.0K	0.23%
Tao Capital Management LP	3,042	$66.0K	0.06%
Caption Management, LLC	3,000	$64.4K	0.01%
Principal Securities, Inc.	806	$17.3K	0.00%
Cutler Group LP	400	$8.00K	0.00%
Advisory Services Network, LLC	309	$6.63K	0.00%
Morton Brown Family Wealth, LLC	298	$6.39K	0.00%
Farther Finance Advisors, LLC	84	$1.80K	0.00%
Cubist Systematic Strategies, LLC	77	$1.65K	0.00%
Private Wealth Management Group, LLC	49	$1.05K	0.00%
GAMMA Investing LLC	46	$736	0.00%
Naples Money Management LLC	33	$708	0.00%
Versant Capital Management, Inc	8	$172	0.00%

Sold out (21)

Institutions that held Denali Therapeutics Inc. at the end of Q3 2023 and filed for Q4 2023 without it.

Institutions that sold out of DNLI in Q4 2023
Institution	Shares, Q3 2023	Value, Q3 2023
Eventide Asset Management, LLC	621,850	$12.8M
Deerfield Management Company, L.P. (Series C)	594,989	$12.3M
Man Group plc	–	$8.74M
TCW Group Inc	141,924	$2.93M
Millennium Management LLC	118,351	$2.44M
Susquehanna Fundamental Investments, LLC	81,308	$1.68M
XTX Topco Ltd	44,656	$921.3K
Trexquant Investment LP	42,349	$873.7K
Tudor Investment Corp Et Al	42,020	$866.9K
Capula Management Ltd	38,720	$798.8K
Gsa Capital Partners LLP	37,404	$772.0K
SG Americas Securities, LLC	35,800	$739.0K
Y-Intercept (Hong Kong) Ltd	26,618	$549.1K
Jump Financial, LLC	19,787	$408.2K
Gotham Asset Management, LLC	19,391	$400.0K
ExodusPoint Capital Management, LP	17,381	$359.0K
Bayesian Capital Management, LP	13,942	$287.6K
Teza Capital Management LLC	10,818	$223.2K
Raymond James & Associates	9,894	$204.1K
Umb Bank N A	306	$6.31K
Tfo-TDC, LLC	12	$354

Not filed for Q4 2023 yet (2)

Institutions that held Denali Therapeutics Inc. at the end of Q3 2023 and haven't filed a 13F for Q4 2023. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding DNLI in Q3 2023 that haven't filed for Q4 2023
Institution	Shares, Q3 2023	Value, Q3 2023
International Biotechnology Trust PLC	154,000	$3.17M
Virginia Retirement Systems Et Al	11,600	$239.3K