Denali Therapeutics Inc.
DNLI- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.
13F holders, Q4 2023
Institutional positions in Denali Therapeutics Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 209
- +16 vs. Q3 2023
- Shares held
- 115.0M
- +6.57M (+6.1%) vs. Q3 2023
- Total value
- $2.47B
- +$224.9M (+10.0%) vs. Q3 2023
- New holders
- 37
- 71 more added
- Sold out
- 21
- 69 more reduced
2 institutions that held it in Q3 2023 haven't filed for Q4 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 294 | $4.00B |
| Q1 2026 | 269 | $2.82B |
| Q4 2025 | 250 | $2.50B |
| Q3 2025 | 240 | $1.97B |
| Q2 2025 | 231 | $1.93B |
| Q1 2025 | 222 | $1.85B |
| Q4 2024 | 224 | $2.61B |
| Q3 2024 | 217 | $3.69B |
| Q2 2024 | 203 | $2.88B |
| Q1 2024 | 211 | $2.51B |
| Q4 2023 | 209 | $2.47B |
| Q3 2023 | 195 | $2.24B |
| Q2 2023 | 203 | $3.18B |
| Q1 2023 | 202 | $2.49B |
| Q4 2022 | 199 | $2.94B |
| Q3 2022 | 200 | $2.84B |
| Q2 2022 | 188 | $2.73B |
| Q1 2022 | 190 | $2.79B |
| Q4 2021 | 213 | $3.80B |
| Q3 2021 | 214 | $4.28B |
| Q2 2021 | 210 | $6.32B |
| Q1 2021 | 218 | $4.60B |
Institutions, Q4 2023
Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q3 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| American International Group, Inc. | 58,725 | $1.26M | 0.01% | −237−0.4% | Reduced |
| Profund Advisors LLC | 53,675 | $1.15M | 0.05% | +13,521+33.7% | Added |
| Franklin Resources Inc | 53,201 | $1.14M | 0.00% | −6,150−10.4% | Reduced |
| Janus Henderson Group PLC | 52,692 | $1.13M | 0.00% | −75−0.1% | Reduced |
| Bamco Inc | 50,500 | $1.08M | 0.00% | 00.0% | Unchanged |
| Los Angeles Capital Management LLC | 46,558 | $999.1K | 0.00% | +556+1.2% | Added |
| Healthcare of Ontario Pension Plan Trust Fund | 46,000 | $987.2K | 0.00% | +25,800+127.7% | Added |
| Pier 88 Investment Partners LLC | 45,240 | $970.9K | 0.24% | −5,460−10.8% | Reduced |
| HRT Financial LP | 44,292 | $950.0K | 0.01% | +32,087+262.9% | Added |
| Twinbeech Capital LP | 40,580 | $870.8K | 0.01% | +40,580 | New |
| ClariVest Asset Management LLC | 40,180 | $862.3K | 0.05% | −2,721−6.3% | Reduced |
| HighTower Advisors, LLC | 39,633 | $858.0K | 0.00% | −14,699−27.1% | Reduced |
| Royal Bank of Canada | 38,841 | $834.0K | 0.00% | +20,867+116.1% | Added |
| Concentric Wealth Management, LLC | 36,486 | $783.0K | 0.23% | 00.0% | Unchanged |
| Groupama Asset Managment | 35,013 | $751.6K | 0.02% | +35,013 | New |
| UBS Oconnor LLC | 34,464 | $739.6K | 0.02% | −24,488−41.5% | Reduced |
| State Board of Administration of Florida Retirement System | 33,718 | $723.6K | 0.00% | 00.0% | Unchanged |
| PDT Partners, LLC | 32,900 | $706.0K | 0.08% | +32,900 | New |
| Arizona State Retirement System | 30,733 | $659.5K | 0.01% | −448−1.4% | Reduced |
| University of Texas/Texas Am Investment Managment Co | 30,428 | $653.0K | 0.18% | +30,428 | New |
| Thrivent Financial for Lutherans | 29,682 | $637.0K | 0.00% | +29,682 | New |
| ProShare Advisors LLC | 28,385 | $609.1K | 0.00% | +4,053+16.7% | Added |
| Two Sigma Investments, LP | 28,376 | $608.9K | 0.00% | +28,376 | New |
| Erste Asset Management GmbH | 26,900 | $590.5K | 0.01% | −307,769−92.0% | Reduced |
| Dynamic Technology Lab Private Ltd | 27,429 | $589.0K | 0.06% | +4,340+18.8% | Added |
| VELA Investment Management, LLC | 26,145 | $561.1K | 0.23% | +6,246+31.4% | Added |
| Teacher Retirement System of Texas | 25,426 | $546.0K | 0.00% | −5,676−18.2% | Reduced |
| Creative Planning | 24,810 | $532.4K | 0.00% | +10,394+72.1% | Added |
| Landscape Capital Management, L.L.C. | 24,318 | $521.9K | 0.05% | +24,318 | New |
| Dana Investment Advisors, Inc. | 24,057 | $516.3K | 0.02% | −572−2.3% | Reduced |
| Levin Capital Strategies, L.P. | 24,000 | $515.0K | 0.06% | +10,000+71.4% | Added |
| Handelsbanken Fonder AB | 23,900 | $513.0K | 0.00% | +6,700+39.0% | Added |
| Envestnet Asset Management Inc | 23,561 | $505.6K | 0.00% | +440+1.9% | Added |
| Capstone Investment Advisors, LLC | 22,889 | $491.2K | 0.01% | −14,678−39.1% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 22,787 | $489.0K | 0.00% | +2,108+10.2% | Added |
| Employees Retirement System of Texas | 21,375 | $459.0K | 0.01% | +21,375 | New |
| Schonfeld Strategic Advisors LLC | 18,327 | $393.3K | 0.00% | +18,327 | New |
| Ironwood Investment Management LLC | 17,938 | $384.9K | 0.20% | −158−0.9% | Reduced |
| Guggenheim Capital LLC | 17,396 | $373.3K | 0.00% | −39,974−69.7% | Reduced |
| E Fund Management Co., Ltd. | 17,290 | $371.0K | 0.02% | +5,509+46.8% | Added |
| Amalgamated Bank | 17,057 | $366.0K | 0.00% | −1,198−6.6% | Reduced |
| HSBC Holdings PLC | 16,892 | $364.0K | 0.00% | −535−3.1% | Reduced |
| Walleye Capital LLC | 16,728 | $359.0K | 0.01% | +16,728 | New |
| China Universal Asset Management Co., Ltd. | 15,981 | $343.0K | 0.07% | +12,455+353.2% | Added |
| Virtu Financial LLC | 15,576 | $334.0K | 0.03% | +15,576 | New |
| Allianz Asset Management GmbH | 15,400 | $330.5K | 0.00% | +700+4.8% | Added |
| Victory Capital Management Inc | 15,348 | $329.4K | 0.00% | +3,267+27.0% | Added |
| Squarepoint Ops LLC | 14,319 | $307.3K | 0.00% | −95,750−87.0% | Reduced |
| STRS Ohio | 13,800 | $296.0K | 0.00% | 00.0% | Unchanged |
| Stifel Financial Corp | 12,895 | $276.7K | 0.00% | +541+4.4% | Added |
| Sectoral Asset Management Inc | 12,881 | $276.4K | 0.12% | −242,060−94.9% | Reduced |
| Engineers Gate Manager LP | 12,672 | $271.9K | 0.01% | −10,937−46.3% | Reduced |
| Public Employees Retirement Association of Colorado | 12,238 | $263.0K | 0.00% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 12,230 | $262.5K | 0.01% | +492+4.2% | Added |
| SEI Investments Co | 11,861 | $254.5K | 0.00% | −399−3.3% | Reduced |
| Arthur M. Cohen & Associates, LLC | 10,564 | $226.7K | 0.05% | −2,377−18.4% | Reduced |
| Prelude Capital Management, LLC | 10,344 | $222.0K | 0.02% | +40+0.4% | Added |
| Quest Partners LLC | 9,965 | $213.8K | 0.05% | +9,965 | New |
| Great West Life Assurance Co | 9,724 | $207.0K | 0.00% | 00.0% | Unchanged |
| Brandywine Managers, LLC | 9,601 | $206.0K | 0.23% | +9,601 | New |
| Aquatic Capital Management LLC | 8,300 | $178.0K | 0.00% | −10,000−54.6% | Reduced |
| Covestor Ltd | 7,155 | $154.0K | 0.11% | +6,865+2,367.2% | Added |
| Metropolitan Life Insurance Co | 6,806 | $146.1K | 0.01% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 5,724 | $122.8K | 0.00% | +4,016+235.1% | Added |
| Allspring Global Investments Holdings, LLC | 5,641 | $121.1K | 0.00% | +475+9.2% | Added |
| Lazard Asset Management LLC | 4,410 | $94.0K | 0.00% | −6,451−59.4% | Reduced |
| Virtus ETF Advisers LLC | 3,994 | $85.7K | 0.05% | +949+31.2% | Added |
| Assetmark, Inc | 3,550 | $76.2K | 0.00% | +1,402+65.3% | Added |
| Tao Capital Management LP | 3,042 | $66.0K | 0.06% | +3,042 | New |
| Caption Management, LLC | 3,000 | $64.4K | 0.01% | +3,000 | New |
| The PNC Financial Services Group, Inc. | 2,486 | $53.3K | 0.00% | +807+48.1% | Added |
| KBC Group NV | 2,465 | $53.0K | 0.00% | 00.0% | Unchanged |
| CWM, LLC | 2,011 | $43.0K | 0.00% | +1,376+216.7% | Added |
| Bartlett & Co. LLC | 1,500 | $33.0K | 0.00% | −23,300−94.0% | Reduced |
| Bartlett & Co. Wealth Management LLC | 1,500 | $32.9K | 0.00% | −23,300−94.0% | Reduced |
| Advisor Group Holdings, Inc. | 1,512 | $32.4K | 0.00% | −3,165−67.7% | Reduced |
| Signaturefd, LLC | 920 | $19.7K | 0.00% | +294+47.0% | Added |
| Allworth Financial LP | 889 | $19.1K | 0.00% | +840+1,714.3% | Added |
| Principal Securities, Inc. | 806 | $17.3K | 0.00% | +806 | New |
| Nemes Rush Group LLC | 700 | $15.0K | 0.00% | 00.0% | Unchanged |
| Lindbrook Capital, LLC | 646 | $13.9K | 0.00% | +407+170.3% | Added |
| Comerica Bank | 611 | $13.1K | 0.00% | +293+92.1% | Added |
| Daiwa Securities Group Inc. | 546 | $12.0K | 0.00% | 00.0% | Unchanged |
| US Bancorp | 499 | $10.7K | 0.00% | −341−40.6% | Reduced |
| Cutler Group LP | 400 | $8.00K | 0.00% | +400 | New |
| Huntington National Bank | 350 | $7.51K | 0.00% | −5−1.4% | Reduced |
| NBC Securities, Inc. | 335 | $7.00K | 0.00% | 00.0% | Unchanged |
| Advisory Services Network, LLC | 309 | $6.63K | 0.00% | +309 | New |
| Morton Brown Family Wealth, LLC | 298 | $6.39K | 0.00% | +298 | New |
| EverSource Wealth Advisors, LLC | 258 | $5.54K | 0.00% | +42+19.4% | Added |
| City State Bank | 250 | $5.00K | 0.00% | 00.0% | Unchanged |
| First Horizon Advisors, Inc. | 220 | $4.72K | 0.00% | 00.0% | Unchanged |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 145 | $2.95K | 0.00% | 00.0% | Unchanged |
| Activest Wealth Management | 131 | $2.81K | 0.00% | 00.0% | Unchanged |
| Massmutual Trust Co FSB | 117 | $2.51K | 0.00% | +84+254.5% | Added |
| Your Advocates Ltd., LLP | 100 | $2.15K | 0.00% | 00.0% | Unchanged |
| Farther Finance Advisors, LLC | 84 | $1.80K | 0.00% | +84 | New |
| Parallel Advisors, LLC | 83 | $1.78K | 0.00% | −237−74.1% | Reduced |
| Bell Investment Advisors, Inc | 77 | $1.65K | 0.00% | +34+79.1% | Added |
| Cubist Systematic Strategies, LLC | 77 | $1.65K | 0.00% | +77 | New |