Denali Therapeutics Inc.
DNLI- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.
13F holders, Q4 2021
Institutional positions in Denali Therapeutics Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 213
- +2 vs. Q3 2021
- Shares held
- 85.3M
- +675.1K (+0.8%) vs. Q3 2021
- Total value
- $3.80B
- −$465.4M (−10.9%) vs. Q3 2021
- New holders
- 29
- 86 more added
- Sold out
- 27
- 62 more reduced
3 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 294 | $4.00B |
| Q1 2026 | 269 | $2.82B |
| Q4 2025 | 250 | $2.50B |
| Q3 2025 | 240 | $1.97B |
| Q2 2025 | 231 | $1.93B |
| Q1 2025 | 222 | $1.85B |
| Q4 2024 | 224 | $2.61B |
| Q3 2024 | 217 | $3.69B |
| Q2 2024 | 203 | $2.88B |
| Q1 2024 | 211 | $2.51B |
| Q4 2023 | 209 | $2.47B |
| Q3 2023 | 195 | $2.24B |
| Q2 2023 | 203 | $3.18B |
| Q1 2023 | 202 | $2.49B |
| Q4 2022 | 199 | $2.94B |
| Q3 2022 | 200 | $2.84B |
| Q2 2022 | 188 | $2.73B |
| Q1 2022 | 190 | $2.79B |
| Q4 2021 | 213 | $3.80B |
| Q3 2021 | 214 | $4.28B |
| Q2 2021 | 210 | $6.32B |
| Q1 2021 | 218 | $4.60B |
Institutions, Q4 2021
Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q3 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Erste Asset Management GmbH | 30,600 | $1.35M | 0.02% | 00.0% | Unchanged |
| Envestnet Asset Management Inc | 28,563 | $1.27M | 0.00% | +2,312+8.8% | Added |
| Concentric Wealth Management, LLC | 27,967 | $1.25M | 0.35% | 00.0% | Unchanged |
| Clarius Group, LLC | 26,445 | $1.18M | 0.09% | +13,750+108.3% | Added |
| International Biotechnology Trust PLC | 26,000 | $1.16M | 0.26% | +26,000 | New |
| Virginia Retirement Systems Et Al | 25,700 | $1.15M | 0.01% | −2,900−10.1% | Reduced |
| Jane Street Group, LLC | 24,456 | $1.09M | 0.00% | +5,759+30.8% | Added |
| Metropolitan Life Insurance Co | 24,089 | $1.07M | 0.01% | 00.0% | Unchanged |
| Arizona State Retirement System | 21,280 | $949.0K | 0.01% | −178−0.8% | Reduced |
| BNP Paribas Arbitrage, SA | 19,699 | $878.6K | 0.00% | +1,700+9.4% | Added |
| Ironwood Investment Management LLC | 19,383 | $864.0K | 0.43% | +290+1.5% | Added |
| Millennium Management LLC | 18,360 | $819.0K | 0.00% | −23,482−56.1% | Reduced |
| Vontobel Holding Ltd. | 17,988 | $810.0K | 0.01% | +3,988+28.5% | Added |
| Handelsbanken Fonder AB | 18,000 | $803.0K | 0.00% | 00.0% | Unchanged |
| Mercer Global Advisors Inc | 17,352 | $774.0K | 0.00% | −2,181−11.2% | Reduced |
| Bartlett & Co. LLC | 16,943 | $756.0K | 0.01% | +15,443+1,029.5% | Added |
| Bartlett & Co. Wealth Management LLC | 16,943 | $755.7K | 0.01% | +15,443+1,029.5% | Added |
| Rockefeller Capital Management L.P. | 16,458 | $733.0K | 0.00% | +1,659+11.2% | Added |
| Amalgamated Bank | 16,012 | $714.0K | 0.01% | −172−1.1% | Reduced |
| Profund Advisors LLC | 15,840 | $706.0K | 0.02% | −1,813−10.3% | Reduced |
| Teacher Retirement System of Texas | 15,569 | $694.0K | 0.00% | +2,996+23.8% | Added |
| First Trust Advisors LP | 15,147 | $676.0K | 0.00% | −65,306−81.2% | Reduced |
| Group One Trading, L.P. | 14,345 | $640.0K | 0.01% | +14,345 | New |
| Voloridge Investment Management, LLC | 13,941 | $622.0K | 0.00% | −4,075−22.6% | Reduced |
| Capital Fund Management S.A. | 13,803 | $615.6K | 0.02% | −3,202−18.8% | Reduced |
| Stifel Financial Corp | 13,655 | $609.0K | 0.00% | −1,012−6.9% | Reduced |
| Balyasny Asset Management LLC | 12,874 | $574.0K | 0.00% | +6,510+102.3% | Added |
| Arthur M. Cohen & Associates, LLC | 12,416 | $554.0K | 0.10% | +4,869+64.5% | Added |
| Public Employees Retirement Association of Colorado | 12,238 | $546.0K | 0.00% | 00.0% | Unchanged |
| Dynamic Technology Lab Private Ltd | 12,160 | $542.0K | 0.06% | +12,160 | New |
| Victory Capital Management Inc | 12,081 | $539.0K | 0.00% | −9,627−44.3% | Reduced |
| Acadian Asset Management LLC | 11,805 | $526.0K | 0.00% | +957+8.8% | Added |
| Utah Retirement Systems | 11,600 | $517.0K | 0.01% | 00.0% | Unchanged |
| SEI Investments Co | 11,352 | $498.0K | 0.00% | −433−3.7% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 10,944 | $488.0K | 0.00% | +2,118+24.0% | Added |
| Nomura Asset Management Co Ltd | 10,402 | $463.9K | 0.00% | +10,402 | New |
| Jump Financial, LLC | 10,203 | $455.0K | 0.03% | +10,203 | New |
| AlphaCrest Capital Management LLC | 9,811 | $438.0K | 0.02% | +3,411+53.3% | Added |
| Dana Investment Advisors, Inc. | 9,638 | $430.0K | 0.02% | +326+3.5% | Added |
| Prelude Capital Management, LLC | 9,610 | $429.0K | 0.02% | +3,598+59.8% | Added |
| Brandywine Managers, LLC | 9,601 | $428.0K | 0.48% | +1,050+12.3% | Added |
| Simplex Trading, LLC | 9,376 | $418.0K | 0.01% | +9,376 | New |
| Royal Bank of Canada | 9,243 | $412.0K | 0.00% | +5,175+127.2% | Added |
| Brown Brothers Harriman & Co | 9,024 | $402.0K | 0.00% | +6,524+261.0% | Added |
| Two Sigma Investments, LP | 8,576 | $382.0K | 0.00% | −105,095−92.5% | Reduced |
| GAM Holding AG | 8,403 | $375.0K | 0.02% | 00.0% | Unchanged |
| Franklin Resources Inc | 8,246 | $368.0K | 0.00% | +8,246 | New |
| Cubist Systematic Strategies, LLC | 7,866 | $351.0K | 0.00% | −1,740−18.1% | Reduced |
| Illinois Municipal Retirement Fund | 7,510 | $335.0K | 0.01% | 00.0% | Unchanged |
| Algert Global LLC | 7,369 | $329.0K | 0.04% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 7,339 | $328.0K | 0.01% | +1,924+35.5% | Added |
| Mackenzie Financial Corp | 7,331 | $327.0K | 0.00% | −143−1.9% | Reduced |
| D. E. Shaw & Co., Inc. | 7,236 | $323.0K | 0.00% | −38,177−84.1% | Reduced |
| Ameritas Investment Partners, Inc. | 7,134 | $318.0K | 0.01% | 00.0% | Unchanged |
| Weiss Asset Management LP | 7,020 | $313.0K | 0.01% | +7,020 | New |
| O'Shaughnessy Asset Management, LLC | 6,687 | $298.0K | 0.01% | −19−0.3% | Reduced |
| Winton Group Ltd | 6,272 | $280.0K | 0.02% | +6,272 | New |
| Gsa Capital Partners LLP | 5,834 | $260.0K | 0.03% | −9,058−60.8% | Reduced |
| Engineers Gate Manager LP | 5,690 | $254.0K | 0.01% | +5,690 | New |
| Vident Investment Advisory, LLC | 5,432 | $242.0K | 0.01% | +5,432 | New |
| Wilbanks Smith & Thomas Asset Management LLC | 5,381 | $240.0K | 0.01% | 00.0% | Unchanged |
| Creative Planning | 5,208 | $232.0K | 0.00% | 00.0% | Unchanged |
| Blair William & Co | 5,100 | $227.0K | 0.00% | 00.0% | Unchanged |
| CIBC Asset Management Inc | 5,069 | $226.0K | 0.00% | +186+3.8% | Added |
| Walled Lake Planning & Wealth Management, LLC | 5,020 | $224.0K | 0.13% | 00.0% | Unchanged |
| Saturna Capital CORP | 5,000 | $223.0K | 0.00% | 00.0% | Unchanged |
| Beacon Investment Advisory Services, Inc. | 5,000 | $223.0K | 0.01% | 00.0% | Unchanged |
| Raymond James & Associates | 4,926 | $220.0K | 0.00% | −1,245−20.2% | Reduced |
| Commonwealth Equity Services, LLC | 4,636 | $206.0K | 0.00% | +472+11.3% | Added |
| Zebra Capital Management LLC | 4,495 | $200.0K | 0.32% | −1,657−26.9% | Reduced |
| Great West Life Assurance Co | 4,462 | $198.0K | 0.00% | 00.0% | Unchanged |
| DuPont Capital Management Corp | 4,320 | $193.0K | 0.01% | −3,807−46.8% | Reduced |
| Quantbot Technologies LP | 3,742 | $166.0K | 0.01% | +3,311+768.2% | Added |
| Virtus ETF Advisers LLC | 3,633 | $162.0K | 0.06% | +803+28.4% | Added |
| Compagnie Lombard Odier SCmA | 3,000 | $134.0K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 3,851 | $132.0K | 0.00% | −2,295−37.3% | Reduced |
| High Net Worth Advisory Group LLC | 2,500 | $112.0K | 0.04% | +2,500 | New |
| Amundi | 3,017 | $102.0K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 2,103 | $95.0K | 0.00% | +542+34.7% | Added |
| Itau Unibanco Holding S.A. | 1,948 | $88.0K | 0.00% | +1,569+414.0% | Added |
| Cutler Group LP | 1,700 | $75.0K | 0.01% | +540+46.6% | Added |
| The PNC Financial Services Group, Inc. | 1,452 | $65.0K | 0.00% | +241+19.9% | Added |
| Point72 Hong Kong Ltd | 1,319 | $59.0K | 0.00% | +420+46.7% | Added |
| Patriot Financial Group Insurance Agency, LLC | 811 | $36.0K | 0.01% | +451+125.3% | Added |
| Lindbrook Capital, LLC | 611 | $27.0K | 0.00% | +611 | New |
| HM Payson & Co | 578 | $26.0K | 0.00% | +578 | New |
| Dark Forest Capital Management LP | 529 | $24.0K | 0.01% | −66−11.1% | Reduced |
| Snowden Capital Advisors LLC | 500 | $22.0K | 0.00% | +500 | New |
| US Bancorp | 444 | $20.0K | 0.00% | +6+1.4% | Added |
| State of Wyoming | 386 | $18.0K | 0.01% | +316+451.4% | Added |
| Daiwa Securities Group Inc. | 356 | $16.0K | 0.00% | −61−14.6% | Reduced |
| City State Bank | 250 | $11.0K | 0.01% | +250 | New |
| TCI Wealth Advisors, Inc. | 216 | $10.0K | 0.00% | +59+37.6% | Added |
| First Horizon Advisors, Inc. | 215 | $9.00K | 0.00% | 00.0% | Unchanged |
| Bedel Financial Consulting, Inc. | 154 | $7.00K | 0.00% | 00.0% | Unchanged |
| Covestor Ltd | 155 | $7.00K | 0.01% | +155 | New |
| Private Capital Group, LLC | 132 | $6.00K | 0.00% | −167−55.9% | Reduced |
| Huntington National Bank | 131 | $6.00K | 0.00% | +1+0.8% | Added |
| Activest Wealth Management | 131 | $6.00K | 0.00% | 00.0% | Unchanged |
| Smith Group Asset Management, LLC | 110 | $5.00K | 0.00% | 00.0% | Unchanged |