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Denali Therapeutics Inc.

DNLI
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001714899

In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.

13F holders, Q1 2024

Institutional positions in Denali Therapeutics Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
211
+3 vs. Q4 2023
Shares held
122.4M
+7.40M (+6.4%) vs. Q4 2023
Total value
$2.51B
+$47.5M (+1.9%) vs. Q4 2023
New holders
36
76 more added
Sold out
33
69 more reduced

1 institution that held it in Q4 2023 haven't filed for Q1 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2024: 211 institutions
Q1 2021: 218 institutionsQ2 2021: 210 institutionsQ3 2021: 214 institutionsQ4 2021: 213 institutionsQ1 2022: 190 institutionsQ2 2022: 188 institutionsQ3 2022: 200 institutionsQ4 2022: 199 institutionsQ1 2023: 202 institutionsQ2 2023: 203 institutionsQ3 2023: 195 institutionsQ4 2023: 209 institutionsQ1 2024: 211 institutionsQ2 2024: 203 institutionsQ3 2024: 217 institutionsQ4 2024: 224 institutionsQ1 2025: 222 institutionsQ2 2025: 231 institutionsQ3 2025: 240 institutionsQ4 2025: 250 institutionsQ1 2026: 269 institutionsQ2 2026: 294 institutions
Value heldQ1 2024: $2.51B
Q1 2021: $4.60BQ2 2021: $6.32BQ3 2021: $4.28BQ4 2021: $3.80BQ1 2022: $2.79BQ2 2022: $2.73BQ3 2022: $2.84BQ4 2022: $2.94BQ1 2023: $2.49BQ2 2023: $3.18BQ3 2023: $2.24BQ4 2023: $2.47BQ1 2024: $2.51BQ2 2024: $2.88BQ3 2024: $3.69BQ4 2024: $2.61BQ1 2025: $1.85BQ2 2025: $1.93BQ3 2025: $1.97BQ4 2025: $2.50BQ1 2026: $2.82BQ2 2026: $4.00B
Institutions holding DNLI and their total value by quarter
QuarterHoldersValue
Q2 2026294$4.00B
Q1 2026269$2.82B
Q4 2025250$2.50B
Q3 2025240$1.97B
Q2 2025231$1.93B
Q1 2025222$1.85B
Q4 2024224$2.61B
Q3 2024217$3.69B
Q2 2024203$2.88B
Q1 2024211$2.51B
Q4 2023209$2.47B
Q3 2023195$2.24B
Q2 2023203$3.18B
Q1 2023202$2.49B
Q4 2022199$2.94B
Q3 2022200$2.84B
Q2 2022188$2.73B
Q1 2022190$2.79B
Q4 2021213$3.80B
Q3 2021214$4.28B
Q2 2021210$6.32B
Q1 2021218$4.60B

Institutions, Q1 2024

Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q4 2023.

Institutions holding DNLI in Q1 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Los Angeles Capital Management LLC55,612$1.14M0.00%+9,054+19.4%Added
Janus Henderson Group PLC52,718$1.08M0.00%+260.0%Added
Franklin Resources Inc50,595$1.04M0.00%−2,606−4.9%Reduced
Bamco Inc50,500$1.04M0.00%00.0%Unchanged
Jane Street Group, LLC48,716$999.7K0.00%−100,249−67.3%Reduced
ClariVest Asset Management LLC47,748$979.8K0.10%+7,568+18.8%Added
Soleus Capital Management, L.P.47,000$964.4K0.08%−83,000−63.8%Reduced
Groupama Asset Managment43,827$899.3K0.02%+8,814+25.2%Added
Employees Retirement System of Texas43,769$898.0K0.01%+22,394+104.8%Added
Skandinaviska Enskilda Banken AB (publ)43,245$887.4K0.00%−304,958−87.6%Reduced
Bank of Montreal42,288$881.3K0.00%+42,288New
EP Wealth Advisors, LLC40,500$831.1K0.01%+40,500New
Pier 88 Investment Partners LLC39,970$820.2K0.20%−5,270−11.6%Reduced
HighTower Advisors, LLC39,220$813.0K0.00%−413−1.0%Reduced
Creative Planning39,575$812.1K0.00%+14,765+59.5%Added
Knights of Columbus Asset Advisors LLC39,441$809.3K0.06%−37,911−49.0%Reduced
Qube Research & Technologies Ltd37,749$774.6K0.00%−133,513−78.0%Reduced
Concentric Wealth Management, LLC36,486$748.7K0.20%00.0%Unchanged
State Board of Administration of Florida Retirement System32,288$743.9K0.00%−1,430−4.2%Reduced
Ironwood Investment Management LLC36,064$740.0K0.36%+18,126+101.0%Added
Eisler Capital (US) LLC34,480$707.5K0.24%+34,480New
LPL Financial LLC34,085$699.4K0.00%+34,085New
University of Texas/Texas Am Investment Managment Co30,428$653.0K0.08%00.0%Unchanged
Engineers Gate Manager LP31,356$643.4K0.02%+18,684+147.4%Added
ProShare Advisors LLC31,205$640.3K0.00%+2,820+9.9%Added
Arizona State Retirement System30,384$623.5K0.00%−349−1.1%Reduced
Dana Investment Advisors, Inc.28,756$590.1K0.02%+4,699+19.5%Added
Harvest Investment Services, LLC27,978$574.1K0.23%+27,978New
Erste Asset Management GmbH26,900$558.7K0.01%00.0%Unchanged
China Universal Asset Management Co., Ltd.26,721$548.3K0.07%+10,740+67.2%Added
UBS Oconnor LLC25,033$513.7K0.01%−9,431−27.4%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)25,031$513.6K0.00%+2,244+9.8%Added
Teacher Retirement System of Texas24,606$505.0K0.00%−820−3.2%Reduced
Handelsbanken Fonder AB23,900$490.0K0.00%00.0%Unchanged
Envestnet Asset Management Inc22,296$457.5K0.00%−1,265−5.4%Reduced
Two Sigma Advisers, LP21,900$449.4K0.00%+21,900New
Bayesian Capital Management, LP21,800$447.3K0.04%+21,800New
NEOS Investment Management LLC21,648$444.2K0.03%+21,648New
E Fund Management Co., Ltd.20,552$421.7K0.03%+3,262+18.9%Added
Seven Eight Capital, LP20,541$421.5K0.04%−52,046−71.7%Reduced
Capstone Investment Advisors, LLC19,741$405.1K0.01%−3,148−13.8%Reduced
Guggenheim Capital LLC19,719$404.6K0.00%+2,323+13.4%Added
HSBC Holdings PLC16,188$332.1K0.00%−704−4.2%Reduced
Allianz Asset Management GmbH15,400$316.0K0.00%00.0%Unchanged
Victory Capital Management Inc14,743$302.5K0.00%−605−3.9%Reduced
Pictet Asset Management Holding SA13,796$283.1K0.00%−425,422−96.9%Reduced
STRS Ohio13,000$266.0K0.00%−800−5.8%Reduced
Stifel Financial Corp12,873$264.2K0.00%−22−0.2%Reduced
Public Employees Retirement Association of Colorado12,238$251.0K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.12,230$251.0K0.01%00.0%Unchanged
Sectoral Asset Management Inc12,081$247.9K0.10%−800−6.2%Reduced
SEI Investments Co12,072$247.7K0.00%+211+1.8%Added
AQR Capital Management LLC11,001$225.7K0.00%+11,001New
Covestor Ltd10,744$220.0K0.14%+3,589+50.2%Added
Mackenzie Financial Corp10,560$216.7K0.00%+10,560New
Prelude Capital Management, LLC10,369$212.8K0.01%+25+0.2%Added
Great West Life Assurance Co9,724$200.0K0.00%00.0%Unchanged
Group One Trading, L.P.8,455$173.5K0.01%+8,455New
SG Americas Securities, LLC7,141$147.0K0.00%+7,141New
Royal Bank of Canada7,059$146.0K0.00%−31,782−81.8%Reduced
Quarry LP7,000$143.6K0.06%+7,000New
Metropolitan Life Insurance Co6,471$132.8K0.01%−335−4.9%Reduced
Allspring Global Investments Holdings, LLC6,160$126.4K0.00%+519+9.2%Added
Fernwood Investment Management, LLC5,000$102.6K0.03%+5,000New
Simplex Trading, LLC4,928$101.0K0.00%+4,928New
Lazard Asset Management LLC4,410$90.0K0.00%00.0%Unchanged
Headlands Technologies LLC4,295$88.1K0.02%+4,295New
Amalgamated Bank4,024$83.0K0.00%−13,033−76.4%Reduced
Virtus ETF Advisers LLC3,735$76.6K0.04%−259−6.5%Reduced
Assetmark, Inc3,314$68.0K0.00%−236−6.6%Reduced
KBC Group NV2,465$51.0K0.00%00.0%Unchanged
Pacer Advisors, Inc.2,025$41.6K0.00%+2,025New
ADAR1 Capital Management, LLC2,000$41.0K0.01%+2,000New
CWM, LLC1,770$36.0K0.00%−241−12.0%Reduced
The PNC Financial Services Group, Inc.1,655$34.0K0.00%−831−33.4%Reduced
Bartlett & Co. Wealth Management LLC1,500$30.8K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)1,425$29.2K0.00%−4,299−75.1%Reduced
New Covenant Trust Company, N.A.784$16.1K0.02%+784New
US Bancorp753$15.5K0.00%+254+50.9%Added
Principal Securities, Inc.731$15.0K0.00%−75−9.3%Reduced
Signaturefd, LLC730$15.0K0.00%−190−20.7%Reduced
Nemes Rush Group LLC700$14.4K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.639$13.1K0.00%−873−57.7%Reduced
Daiwa Securities Group Inc.546$11.0K0.00%00.0%Unchanged
Parallel Advisors, LLC416$8.54K0.00%+333+401.2%Added
Comerica Bank409$8.39K0.00%−202−33.1%Reduced
Cutler Group LP400$8.00K0.00%00.0%Unchanged
Huntington National Bank374$7.67K0.00%+24+6.9%Added
Lindbrook Capital, LLC314$6.44K0.00%−332−51.4%Reduced
NBC Securities, Inc.335$6.00K0.00%00.0%Unchanged
City State Bank250$5.00K0.00%00.0%Unchanged
EverSource Wealth Advisors, LLC292$4.51K0.00%+34+13.2%Added
GAMMA Investing LLC210$4.31K0.00%+164+356.5%Added
Massmutual Trust Co FSB165$3.39K0.00%+48+41.0%Added
Nelson, Van Denburg & Campbell Wealth Management Group, LLC153$3.14K0.00%+153New
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.145$2.98K0.00%00.0%Unchanged
Activest Wealth Management131$2.69K0.00%00.0%Unchanged
Versant Capital Management, Inc109$2.24K0.00%+101+1,262.5%Added
Your Advocates Ltd., LLP100$2.05K0.00%00.0%Unchanged
Allworth Financial LP86$1.76K0.00%−803−90.3%Reduced