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Denali Therapeutics Inc.

DNLI
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001714899

In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.

13F holders, Q3 2022

Institutional positions in Denali Therapeutics Inc. as of Sep 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
200
+13 vs. Q2 2022
Shares held
92.4M
−257.0K (−0.3%) vs. Q2 2022
Total value
$2.84B
+$108.6M (+4.0%) vs. Q2 2022
New holders
32
78 more added
Sold out
19
56 more reduced

1 institution that held it in Q2 2022 haven't filed for Q3 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2022: 200 institutions
Q1 2021: 218 institutionsQ2 2021: 210 institutionsQ3 2021: 214 institutionsQ4 2021: 213 institutionsQ1 2022: 190 institutionsQ2 2022: 188 institutionsQ3 2022: 200 institutionsQ4 2022: 199 institutionsQ1 2023: 202 institutionsQ2 2023: 203 institutionsQ3 2023: 195 institutionsQ4 2023: 209 institutionsQ1 2024: 211 institutionsQ2 2024: 203 institutionsQ3 2024: 217 institutionsQ4 2024: 224 institutionsQ1 2025: 222 institutionsQ2 2025: 231 institutionsQ3 2025: 240 institutionsQ4 2025: 250 institutionsQ1 2026: 269 institutionsQ2 2026: 294 institutions
Value heldQ3 2022: $2.84B
Q1 2021: $4.60BQ2 2021: $6.32BQ3 2021: $4.28BQ4 2021: $3.80BQ1 2022: $2.79BQ2 2022: $2.73BQ3 2022: $2.84BQ4 2022: $2.94BQ1 2023: $2.49BQ2 2023: $3.18BQ3 2023: $2.24BQ4 2023: $2.47BQ1 2024: $2.51BQ2 2024: $2.88BQ3 2024: $3.69BQ4 2024: $2.61BQ1 2025: $1.85BQ2 2025: $1.93BQ3 2025: $1.97BQ4 2025: $2.50BQ1 2026: $2.82BQ2 2026: $4.00B
Institutions holding DNLI and their total value by quarter
QuarterHoldersValue
Q2 2026294$4.00B
Q1 2026269$2.82B
Q4 2025250$2.50B
Q3 2025240$1.97B
Q2 2025231$1.93B
Q1 2025222$1.85B
Q4 2024224$2.61B
Q3 2024217$3.69B
Q2 2024203$2.88B
Q1 2024211$2.51B
Q4 2023209$2.47B
Q3 2023195$2.24B
Q2 2023203$3.18B
Q1 2023202$2.49B
Q4 2022199$2.94B
Q3 2022200$2.84B
Q2 2022188$2.73B
Q1 2022190$2.79B
Q4 2021213$3.80B
Q3 2021214$4.28B
Q2 2021210$6.32B
Q1 2021218$4.60B

Institutions, Q3 2022

Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q2 2022.

Institutions holding DNLI in Q3 2022
InstitutionSharesValue% of portfolioChange in sharesAction
AIA Group Ltd37,026$1.14M0.07%−38−0.1%Reduced
Man Group plc34,421$1.06M0.00%+34,421New
STRS Ohio33,700$1.03M0.00%00.0%Unchanged
State Board of Administration of Florida Retirement System32,288$991.0K0.00%00.0%Unchanged
Bellevue Group AG31,000$951.0K0.01%+31,000New
PDT Partners, LLC30,588$939.0K0.14%−5,753−15.8%Reduced
Teacher Retirement System of Texas28,221$866.0K0.01%+14,342+103.3%Added
Concentric Wealth Management, LLC27,967$858.0K0.32%00.0%Unchanged
Jackson Creek Investment Advisors LLC27,381$840.0K0.39%+27,381New
Mercer Global Advisors Inc26,209$804.0K0.00%+2,346+9.8%Added
Hillsdale Investment Management Inc.25,700$789.0K0.07%+25,700New
Erste Asset Management GmbH26,900$787.9K0.02%00.0%Unchanged
Trexquant Investment LP25,629$787.0K0.03%+25,629New
ExodusPoint Capital Management, LP23,434$719.0K0.01%−40,753−63.5%Reduced
Arizona State Retirement System23,388$718.0K0.01%+221+1.0%Added
ProShare Advisors LLC22,789$700.0K0.00%+615+2.8%Added
Wellington Management Group LLP21,694$666.0K0.00%+21,694New
Bartlett & Co. LLC20,780$638.0K0.01%+2,269+12.3%Added
Bartlett & Co. Wealth Management LLC20,780$637.7K0.01%+2,269+12.3%Added
Dana Investment Advisors, Inc.20,397$626.0K0.04%+7,047+52.8%Added
AlphaCrest Capital Management LLC20,234$621.0K0.04%+6,934+52.1%Added
Ironwood Investment Management LLC19,908$611.0K0.43%+52+0.3%Added
Duality Advisers, LP19,728$605.0K0.07%+19,728New
Arrowstreet Capital, Limited Partnership18,725$575.0K0.00%+18,725New
HighTower Advisors, LLC18,823$573.0K0.00%+18,823New
Nisa Investment Advisors, LLC17,918$544.0K0.00%+102+0.6%Added
SEI Investments Co16,018$492.0K0.00%+5,660+54.6%Added
Amalgamated Bank15,942$489.0K0.00%+380+2.4%Added
Janus Henderson Group PLC15,890$488.0K0.00%−178−1.1%Reduced
Arthur M. Cohen & Associates, LLC15,338$471.0K0.13%+2,922+23.5%Added
Fox Run Management, L.L.C.14,977$460.0K0.18%+14,977New
Gotham Asset Management, LLC14,607$448.0K0.01%−678−4.4%Reduced
Delphia (USA) Inc.14,414$442.0K0.50%−3,172−18.0%Reduced
E Fund Management Co., Ltd.14,254$437.0K0.04%+2,613+22.4%Added
Tower Research Capital LLC (TRC)14,216$437.0K0.01%+3,700+35.2%Added
Corton Capital Inc.14,154$434.0K0.53%−1,819−11.4%Reduced
Stifel Financial Corp13,548$415.0K0.00%+558+4.3%Added
Handelsbanken Fonder AB13,400$411.0K0.00%00.0%Unchanged
Squarepoint Ops LLC13,365$410.0K0.00%+13,365New
NinePointTwo Capital13,171$404.0K0.16%+13,171New
Virginia Retirement Systems Et Al13,000$399.0K0.00%+13,000New
Profund Advisors LLC12,962$398.0K0.03%+186+1.5%Added
SG Americas Securities, LLC12,851$394.0K0.01%−26,465−67.3%Reduced
Public Employees Retirement Association of Colorado12,238$376.0K0.00%00.0%Unchanged
Pier 88 Investment Partners LLC12,090$371.0K0.09%−990−7.6%Reduced
XTX Topco Ltd12,023$369.0K0.09%+12,023New
Rockefeller Capital Management L.P.11,834$362.0K0.00%+604+5.4%Added
Victory Capital Management Inc11,625$357.0K0.00%+742+6.8%Added
Zurcher Kantonalbank (Zurich Cantonalbank)11,508$353.0K0.00%00.0%Unchanged
Allianz Asset Management GmbH11,300$347.0K0.00%−3,520−23.8%Reduced
Brandywine Managers, LLC9,601$295.0K0.97%00.0%Unchanged
Levin Capital Strategies, L.P.9,500$292.0K0.04%+7,000+280.0%Added
VELA Investment Management, LLC8,841$271.0K0.15%+8,841New
Prudential Financial Inc8,289$243.0K0.00%+54+0.7%Added
HSBC Holdings PLC7,674$239.0K0.00%+7,674New
Algert Global LLC7,634$234.0K0.01%+7,634New
Ameritas Investment Partners, Inc.7,469$229.0K0.01%00.0%Unchanged
Creative Planning7,288$224.0K0.00%+213+3.0%Added
Dynamic Technology Lab Private Ltd7,140$219.0K0.02%+7,140New
Mackenzie Financial Corp6,521$200.0K0.00%−377−5.5%Reduced
Metropolitan Life Insurance Co5,945$182.5K0.01%00.0%Unchanged
Lazard Asset Management LLC5,353$164.0K0.00%00.0%Unchanged
Virtus ETF Advisers LLC4,875$150.0K0.06%+36+0.7%Added
Point72 Hong Kong Ltd4,753$146.0K0.01%+4,753New
Great West Life Assurance Co4,642$142.0K0.00%00.0%Unchanged
Royal Bank of Canada4,015$123.0K0.00%−9,392−70.1%Reduced
Quantbot Technologies LP3,700$113.0K0.01%+2,900+362.5%Added
Simplex Trading, LLC3,450$105.0K0.00%+3,450New
Allspring Global Investments Holdings, LLC3,313$101.0K0.00%+1,005+43.5%Added
Amundi3,017$96.0K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.2,830$87.0K0.00%+566+25.0%Added
Macquarie Group Ltd832$72.0K0.00%−579−41.0%Reduced
Exchange Traded Concepts, LLC2,176$67.0K0.00%+302+16.1%Added
Itau Unibanco Holding S.A.1,398$43.0K0.00%−553−28.3%Reduced
China Universal Asset Management Co., Ltd.1,155$35.0K0.01%+1,155New
High Net Worth Advisory Group LLC1,000$31.0K0.01%−1,000−50.0%Reduced
The PNC Financial Services Group, Inc.901$27.0K0.00%+83+10.1%Added
Cutler Group LP800$24.0K0.00%+120+17.6%Added
US Bancorp503$15.0K0.00%+46+10.1%Added
Daiwa Securities Group Inc.458$14.0K0.00%00.0%Unchanged
Assetmark, Inc438$13.0K0.00%+438New
Huntington National Bank347$11.0K0.00%+209+151.4%Added
Umb Bank N A306$9.00K0.00%−138−31.1%Reduced
Lindbrook Capital, LLC277$9.00K0.00%+54+24.2%Added
City State Bank250$8.00K0.01%00.0%Unchanged
First Horizon Advisors, Inc.215$6.00K0.00%00.0%Unchanged
Covestor Ltd203$6.00K0.01%+190+1,461.5%Added
Activest Wealth Management131$4.00K0.00%00.0%Unchanged
Your Advocates Ltd., LLP100$3.00K0.00%00.0%Unchanged
Leonteq Securities AG90$2.76K0.00%−13−12.6%Reduced
CWM, LLC80$2.00K0.00%+11+15.9%Added
Bell Investment Advisors, Inc64$2.00K0.00%00.0%Unchanged
Quadrant Capital Group LLC50$2.00K0.00%+50New
Signaturefd, LLC40$1.00K0.00%+35+700.0%Added
Allworth Financial LP8$00.00%00.0%Unchanged
Institutional & Family Asset Management, LLC6$00.00%00.0%Unchanged
Parallel Advisors, LLC10$00.00%00.0%Unchanged
Global Retirement Partners, LLC3$00.00%00.0%Unchanged
Capital Advisors, Ltd. LLC6$00.00%+6New
Ronald Blue Trust, Inc.6$00.00%+6New