Denali Therapeutics Inc.
DNLI- 交易所
- Nasdaq
- 產業
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
近 90 天，Denali Therapeutics Inc. 內部人申報 0 筆公開市場買進、4 筆賣出；2026 年第 2 季末有 294 家機構在 13F 申報持有，市值合計 $44.6 億；沒有大師持有。
2026 年第 2 季 13F 持有人
Denali Therapeutics Inc. 在 2026/6/30 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 294
- 較 2026 年第 1 季 +28 家
- 持有股數
- 1.56 億
- 較 2026 年第 1 季 +845.8 萬 (+5.7%)
- 總市值
- $44.6 億
- 較 2026 年第 1 季 +$16.3 億 (+57.7%)
- 新進機構
- 56
- 另有 120 家加碼
- 清倉機構
- 28
- 另有 68 家減碼
另有 3 家機構在 2026 年第 1 季持有、還沒有申報 2026 年第 2 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 DNLI 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 294 | $44.6 億 |
| 2026 年第 1 季 | 269 | $28.3 億 |
| 2025 年第 4 季 | 250 | $25.2 億 |
| 2025 年第 3 季 | 240 | $19.7 億 |
| 2025 年第 2 季 | 231 | $19.3 億 |
| 2025 年第 1 季 | 222 | $18.5 億 |
| 2024 年第 4 季 | 224 | $26.1 億 |
| 2024 年第 3 季 | 217 | $37.0 億 |
| 2024 年第 2 季 | 203 | $28.9 億 |
| 2024 年第 1 季 | 211 | $25.5 億 |
| 2023 年第 4 季 | 209 | $25.0 億 |
| 2023 年第 3 季 | 195 | $22.4 億 |
| 2023 年第 2 季 | 203 | $31.8 億 |
| 2023 年第 1 季 | 202 | $25.1 億 |
| 2022 年第 4 季 | 199 | $29.4 億 |
| 2022 年第 3 季 | 200 | $28.4 億 |
| 2022 年第 2 季 | 188 | $27.4 億 |
| 2022 年第 1 季 | 190 | $28.1 億 |
| 2021 年第 4 季 | 213 | $38.1 億 |
| 2021 年第 3 季 | 214 | $42.8 億 |
| 2021 年第 2 季 | 210 | $63.3 億 |
| 2021 年第 1 季 | 218 | $46.0 億 |
2026 年第 2 季持有機構
每家機構持有 Denali Therapeutics Inc. 的股數、市值與佔組合比重；股數變化跟 2026 年第 1 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| Banque Cantonale Vaudoise | 17,926 | $4.61 億 | 0.06% | +17,926 | 新進 |
| T. Rowe Price Investment Management, Inc. | 16,178,963 | $4.16 億 | 0.27% | +7,659,771+89.9% | 加碼 |
| BlackRock, Inc. | 14,026,413 | $3.61 億 | 0.01% | +991,979+7.6% | 加碼 |
| Baillie Gifford & Co | 11,960,230 | $3.08 億 | 0.28% | −106,249−0.9% | 減碼 |
| State Street Corp | 7,049,304 | $1.81 億 | 0.01% | +777,303+12.4% | 加碼 |
| Temasek Holdings (Private) Ltd | 7,012,974 | $1.80 億 | 0.49% | 00.0% | 不變 |
| Vanguard Portfolio Management LLC | 6,477,057 | $1.67 億 | 0.01% | +356,897+5.8% | 加碼 |
| Vanguard Capital Management LLC | 6,275,729 | $1.61 億 | 0.00% | +127,772+2.1% | 加碼 |
| FMR LLC | 4,535,836 | $1.17 億 | 0.01% | −39,538−0.9% | 減碼 |
| Goldman Sachs Group Inc | 4,155,895 | $1.07 億 | 0.01% | −251,360−5.7% | 減碼 |
| Geode Capital Management, LLC | 3,973,342 | $1.02 億 | 0.01% | +246,228+6.6% | 加碼 |
| Holocene Advisors, LP | 3,905,225 | $1.00 億 | 0.23% | +709,796+22.2% | 加碼 |
| Baker Bros. Advisors LP | 3,734,336 | $9,605 萬 | 0.48% | +2,641+0.1% | 加碼 |
| UBS Asset Management Americas Inc | 3,161,972 | $8,133 萬 | 0.01% | −1,270,342−28.7% | 減碼 |
| Price T Rowe Associates Inc | 3,136,149 | $8,066 萬 | 0.01% | +672,003+27.3% | 加碼 |
| UBS Group AG | 3,120,592 | $8,026 萬 | 0.01% | +549,248+21.4% | 加碼 |
| Dimensional Fund Advisors LP | 2,860,604 | $7,358 萬 | 0.01% | +168,429+6.3% | 加碼 |
| Norges Bank | 2,824,746 | $7,265 萬 | 0.01% | +2,824,746 | 新進 |
| Pictet Asset Management Holding SA | 2,791,206 | $7,189 萬 | 0.07% | +232,341+9.1% | 加碼 |
| Capital Research Global Investors | 2,565,817 | $6,599 萬 | 0.01% | +51,229+2.0% | 加碼 |
| Fisher Asset Management, LLC | 2,414,162 | $6,209 萬 | 0.02% | −22,733−0.9% | 減碼 |
| Alliancebernstein L.P. | 2,984,807 | $5,731 萬 | 0.02% | +91,189+3.2% | 加碼 |
| Nomura Asset Management International Inc. | 2,208,263 | $5,680 萬 | 0.09% | +2,093,739+1,828.2% | 加碼 |
| Casdin Capital, LLC | 2,045,000 | $5,260 萬 | 2.63% | +205,000+11.1% | 加碼 |
| Crestline Management, LP | 1,910,732 | $4,914 萬 | 91.90% | −300,000−13.6% | 減碼 |
| Principal Financial Group Inc | 1,420,083 | $3,652 萬 | 0.02% | −58,403−4.0% | 減碼 |
| Foresite Capital Management VI LLC | 1,396,771 | $3,592 萬 | 5.59% | +186,800+15.4% | 加碼 |
| Siren, L.L.C. | 1,396,513 | $3,592 萬 | 0.73% | 00.0% | 不變 |
| Northern Trust Corp | 1,389,765 | $3,574 萬 | 0.00% | +79,109+6.0% | 加碼 |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 1,355,514 | $3,486 萬 | 0.03% | +1,059,011+357.2% | 加碼 |
| Standard Life Aberdeen plc | 1,345,481 | $3,461 萬 | 0.05% | −508,965−27.4% | 減碼 |
| Charles Schwab Investment Management Inc | 1,244,955 | $3,202 萬 | 0.00% | +37,556+3.1% | 加碼 |
| Bank of America Corp | 1,230,957 | $3,166 萬 | 0.00% | +96,774+8.5% | 加碼 |
| Artisan Partners Limited Partnership | 1,224,497 | $3,149 萬 | 0.05% | +124,778+11.3% | 加碼 |
| Candriam Luxembourg S.C.A. | 1,189,886 | $3,057 萬 | 0.14% | +90,041+8.2% | 加碼 |
| Millennium Management LLC | 1,125,748 | $2,895 萬 | 0.02% | −132,202−10.5% | 減碼 |
| ADAR1 Capital Management, LLC | 1,029,080 | $2,647 萬 | 1.24% | −842,375−45.0% | 減碼 |
| Vanguard Fiduciary Trust Co | 991,904 | $2,551 萬 | 0.01% | +42,209+4.4% | 加碼 |
| Morgan Stanley | 961,050 | $2,472 萬 | 0.00% | −143,707−13.0% | 減碼 |
| Bank of New York Mellon Corp | 800,283 | $2,058 萬 | 0.00% | +32,244+4.2% | 加碼 |
| DAFNA Capital Management LLC | 739,014 | $1,901 萬 | 3.62% | +420,514+132.0% | 加碼 |
| American Century Companies Inc | 712,526 | $1,833 萬 | 0.01% | −223,166−23.9% | 減碼 |
| Cercano Management LLC | 625,000 | $1,608 萬 | 2.14% | 00.0% | 不變 |
| Nuveen, LLC | 608,967 | $1,566 萬 | 0.00% | +313,381+106.0% | 加碼 |
| Ensign Peak Advisors, Inc | 582,669 | $1,499 萬 | 0.02% | +66,948+13.0% | 加碼 |
| Marshall Wace, LLP | 549,830 | $1,414 萬 | 0.01% | −441,438−44.5% | 減碼 |
| Segall Bryant & Hamill, LLC | 519,483 | $1,336 萬 | 0.16% | +8,940+1.8% | 加碼 |
| Citigroup Inc | 487,278 | $1,253 萬 | 0.01% | +448,000+1,140.6% | 加碼 |
| Defilade Capital Management, L.P. | 391,866 | $1,008 萬 | 1.35% | −968,103−71.2% | 減碼 |
| AQR Capital Management LLC | 388,469 | $999.1 萬 | 0.00% | +285,890+278.7% | 加碼 |
| Woodline Partners LP | 364,082 | $936.4 萬 | 0.03% | 00.0% | 不變 |
| Invesco Ltd. | 343,898 | $884.5 萬 | 0.00% | +33,702+10.9% | 加碼 |
| ExodusPoint Capital Management, LP | 336,567 | $865.7 萬 | 0.08% | +336,567 | 新進 |
| Marex Group plc | 295,631 | $760.4 萬 | 0.06% | +8,631+3.0% | 加碼 |
| JPMorgan Chase & Co | 287,019 | $759.3 萬 | 0.00% | −36,970−11.4% | 減碼 |
| Swiss National Bank | 270,500 | $695.7 萬 | 0.00% | −3,300−1.2% | 減碼 |
| TD Asset Management Inc | 231,644 | $595.8 萬 | 0.01% | −24,122−9.4% | 減碼 |
| Groupama Asset Managment | 229,939 | $591.4 萬 | 0.07% | +22,809+11.0% | 加碼 |
| Privium Fund Management B.V. | 229,857 | $591.2 萬 | 1.09% | −25,000−9.8% | 減碼 |
| XTX Topco Ltd | 226,953 | $583.7 萬 | 0.08% | +148,386+188.9% | 加碼 |
| Alyeska Investment Group, L.P. | 219,334 | $564.1 萬 | 0.01% | −1,721,789−88.7% | 減碼 |
| Susquehanna Portfolio Strategies, LLC | 211,474 | $543.9 萬 | 0.09% | +53,578+33.9% | 加碼 |
| Masters Capital Management LLC | 200,000 | $514.4 萬 | 0.72% | −400,000−66.7% | 減碼 |
| Burkehill Global Management, LP | 200,000 | $514.4 萬 | 0.19% | 00.0% | 不變 |
| SCS Capital Management LLC | 197,998 | $509.3 萬 | 0.05% | 00.0% | 不變 |
| Rhumbline Advisers | 194,787 | $501.0 萬 | 0.00% | +10,539+5.7% | 加碼 |
| Wells Fargo & Company | 189,865 | $488.3 萬 | 0.00% | +82,208+76.4% | 加碼 |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 179,195 | $460.9 萬 | 0.01% | +79,692+80.1% | 加碼 |
| Rhenman & Partners Asset Management AB | 179,000 | $460.4 萬 | 0.43% | −20,000−10.1% | 減碼 |
| New York State Common Retirement Fund | 171,712 | $441.6 萬 | 0.01% | +43,593+34.0% | 加碼 |
| Teachers Retirement System of the State of Kentucky | 166,181 | $427.4 萬 | 0.03% | 00.0% | 不變 |
| Edmond de Rothschild Holding S.A. | 165,080 | $424.6 萬 | 0.06% | −60,600−26.9% | 減碼 |
| Alps Advisors Inc | 160,378 | $412.5 萬 | 0.02% | +31,273+24.2% | 加碼 |
| E. Ohman J:or Asset Management AB | 160,000 | $411.5 萬 | 0.10% | +160,000 | 新進 |
| California State Teachers Retirement System | 152,086 | $391.2 萬 | 0.00% | −10,490−6.5% | 減碼 |
| Deutsche Bank AG | 149,804 | $385.3 萬 | 0.00% | +29,436+24.5% | 加碼 |
| Great Lakes Advisors, LLC | 145,045 | $373.1 萬 | 0.03% | −82,065−36.1% | 減碼 |
| Vanguard Asset Management, Ltd | 141,153 | $363.0 萬 | 0.00% | +15,910+12.7% | 加碼 |
| Man Group plc | 139,065 | $357.7 萬 | 0.01% | +200.0% | 加碼 |
| Hudson Bay Capital Management LP | 130,000 | $334.4 萬 | 0.02% | −216,360−62.5% | 減碼 |
| Odyssean, LLC | 125,062 | $321.7 萬 | 0.52% | +125,062 | 新進 |
| Susquehanna International Group, LLP | 123,258 | $317.0 萬 | 0.00% | +72,783+144.2% | 加碼 |
| Manufacturers Life Insurance Company, The | 117,348 | $301.8 萬 | 0.00% | −8,094−6.5% | 減碼 |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 115,775 | $297.8 萬 | 0.01% | +4,081+3.7% | 加碼 |
| B. Metzler seel. Sohn & Co. AG | 112,300 | $288.8 萬 | 0.02% | 00.0% | 不變 |
| Legal & General Group Plc | 111,953 | $287.9 萬 | 0.00% | +1,703+1.5% | 加碼 |
| Integrated Wealth Concepts LLC | 102,241 | $263.0 萬 | 0.02% | +2,687+2.7% | 加碼 |
| PFM Health Sciences, LP | 100,966 | $259.7 萬 | 0.23% | +100,966 | 新進 |
| Ghisallo Capital Management LLC | 100,000 | $257.2 萬 | 0.05% | 00.0% | 不變 |
| Integral Health Asset Management, LLC | 100,000 | $257.2 萬 | 0.11% | +100,000 | 新進 |
| Lumbard & Kellner, LLC | 98,282 | $252.8 萬 | 0.77% | +3,500+3.7% | 加碼 |
| Rafferty Asset Management, LLC | 96,342 | $247.8 萬 | 0.01% | −54,345−36.1% | 減碼 |
| D.A. Davidson & Co. | 87,741 | $225.7 萬 | 0.01% | −22,494−20.4% | 減碼 |
| Russell Investments Group, Ltd. | 86,032 | $221.3 萬 | 0.00% | +71,974+512.0% | 加碼 |
| MetLife Investment Management | 85,621 | $220.2 萬 | 0.01% | +8,063+10.4% | 加碼 |
| Barclays PLC | 84,892 | $218.3 萬 | 0.00% | +32,808+63.0% | 加碼 |
| State of Wisconsin Investment Board | 84,652 | $217.7 萬 | 0.00% | +2,295+2.8% | 加碼 |
| Creative Planning | 84,644 | $217.7 萬 | 0.00% | +10,575+14.3% | 加碼 |
| Ameriprise Financial Inc | 82,650 | $212.6 萬 | 0.00% | −6,884−7.7% | 減碼 |
| Mirae Asset Global ETFs Holdings Ltd. | 78,937 | $203.2 萬 | 0.00% | −16,256−17.1% | 減碼 |