Denali Therapeutics Inc.
DNLI- 交易所
- Nasdaq
- 產業
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
近 90 天，Denali Therapeutics Inc. 內部人申報 0 筆公開市場買進、4 筆賣出；2026 年第 2 季末有 294 家機構在 13F 申報持有，市值合計 $40.0 億；沒有大師持有。
2025 年第 4 季 13F 持有人
Denali Therapeutics Inc. 在 2025/12/31 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 250
- 較 2025 年第 3 季 +17 家
- 持有股數
- 1.51 億
- 較 2025 年第 3 季 +1,619 萬 (+12.0%)
- 總市值
- $25.0 億
- 較 2025 年第 3 季 +$5.36 億 (+27.4%)
- 新進機構
- 51
- 另有 86 家加碼
- 清倉機構
- 34
- 另有 71 家減碼
另有 7 家機構在 2025 年第 3 季持有、還沒有申報 2025 年第 4 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 DNLI 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 294 | $40.0 億 |
| 2026 年第 1 季 | 269 | $28.2 億 |
| 2025 年第 4 季 | 250 | $25.0 億 |
| 2025 年第 3 季 | 240 | $19.7 億 |
| 2025 年第 2 季 | 231 | $19.3 億 |
| 2025 年第 1 季 | 222 | $18.5 億 |
| 2024 年第 4 季 | 224 | $26.1 億 |
| 2024 年第 3 季 | 217 | $36.9 億 |
| 2024 年第 2 季 | 203 | $28.8 億 |
| 2024 年第 1 季 | 211 | $25.1 億 |
| 2023 年第 4 季 | 209 | $24.7 億 |
| 2023 年第 3 季 | 195 | $22.4 億 |
| 2023 年第 2 季 | 203 | $31.8 億 |
| 2023 年第 1 季 | 202 | $24.9 億 |
| 2022 年第 4 季 | 199 | $29.4 億 |
| 2022 年第 3 季 | 200 | $28.4 億 |
| 2022 年第 2 季 | 188 | $27.3 億 |
| 2022 年第 1 季 | 190 | $27.9 億 |
| 2021 年第 4 季 | 213 | $38.0 億 |
| 2021 年第 3 季 | 214 | $42.8 億 |
| 2021 年第 2 季 | 210 | $63.2 億 |
| 2021 年第 1 季 | 218 | $46.0 億 |
2025 年第 4 季持有機構
每家機構持有 Denali Therapeutics Inc. 的股數、市值與佔組合比重；股數變化跟 2025 年第 3 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| Vanguard Group Inc | 13,057,890 | $2.16 億 | 0.00% | +1,064,972+8.9% | 加碼 |
| BlackRock, Inc. | 12,715,201 | $2.10 億 | 0.00% | +425,575+3.5% | 加碼 |
| Baillie Gifford & Co | 12,310,889 | $2.03 億 | 0.17% | +719,304+6.2% | 加碼 |
| T. Rowe Price Investment Management, Inc. | 7,254,132 | $1.20 億 | 0.08% | +1,615,565+28.7% | 加碼 |
| Temasek Holdings (Private) Ltd | 7,012,974 | $1.16 億 | 0.37% | +1,657,142+30.9% | 加碼 |
| State Street Corp | 6,263,371 | $1.03 億 | 0.00% | +799,110+14.6% | 加碼 |
| FMR LLC | 6,097,211 | $1.01 億 | 0.01% | −243,105−3.8% | 減碼 |
| Norges Bank | 5,119,622 | $8,452 萬 | 0.01% | +5,119,622 | 新進 |
| UBS Asset Management Americas Inc | 4,983,726 | $8,228 萬 | 0.02% | −481,311−8.8% | 減碼 |
| Price T Rowe Associates Inc | 3,915,951 | $6,465 萬 | 0.01% | −652,417−14.3% | 減碼 |
| Goldman Sachs Group Inc | 3,835,803 | $6,333 萬 | 0.01% | +1,672,098+77.3% | 加碼 |
| Baker Bros. Advisors LP | 3,731,695 | $6,161 萬 | 0.36% | 00.0% | 不變 |
| Capital Research Global Investors | 3,729,244 | $6,157 萬 | 0.01% | −1,031,614−21.7% | 減碼 |
| Alliancebernstein L.P. | 3,557,935 | $5,874 萬 | 0.02% | +37,521+1.1% | 加碼 |
| Geode Capital Management, LLC | 3,458,131 | $5,710 萬 | 0.00% | −7,926−0.2% | 減碼 |
| Holocene Advisors, LP | 3,152,734 | $5,205 萬 | 0.11% | +17,022+0.5% | 加碼 |
| Crestline Management, LP | 2,810,732 | $4,641 萬 | 87.02% | −600,000−17.6% | 減碼 |
| Fisher Asset Management, LLC | 2,589,403 | $4,275 萬 | 0.01% | +957,907+58.7% | 加碼 |
| UBS Group AG | 2,404,704 | $3,970 萬 | 0.01% | +392,351+19.5% | 加碼 |
| Dimensional Fund Advisors LP | 2,374,303 | $3,920 萬 | 0.01% | +17,089+0.7% | 加碼 |
| Standard Life Aberdeen plc | 2,032,967 | $3,356 萬 | 0.05% | +919,381+82.6% | 加碼 |
| Casdin Capital, LLC | 1,840,000 | $3,038 萬 | 1.89% | +950,000+106.7% | 加碼 |
| Lynx1 Capital Management LP | 1,738,750 | $2,871 萬 | 5.81% | +1,477,063+564.4% | 加碼 |
| Point72 Asset Management, L.P. | 1,700,000 | $2,807 萬 | 0.04% | −819,535−32.5% | 減碼 |
| Principal Financial Group Inc | 1,524,123 | $2,516 萬 | 0.01% | +252,933+19.9% | 加碼 |
| Siren, L.L.C. | 1,396,513 | $2,306 萬 | 0.69% | +575,000+70.0% | 加碼 |
| Pictet Asset Management Holding SA | 1,329,108 | $2,198 萬 | 0.02% | +829,946+166.3% | 加碼 |
| Morgan Stanley | 1,219,854 | $2,014 萬 | 0.00% | −469,638−27.8% | 減碼 |
| Charles Schwab Investment Management Inc | 1,200,475 | $1,982 萬 | 0.00% | +49,091+4.3% | 加碼 |
| Northern Trust Corp | 1,199,744 | $1,981 萬 | 0.00% | −34,435−2.8% | 減碼 |
| Candriam Luxembourg S.C.A. | 1,166,379 | $1,926 萬 | 0.10% | +332,797+39.9% | 加碼 |
| ExodusPoint Capital Management, LP | 1,023,253 | $1,689 萬 | 0.19% | +1,023,253 | 新進 |
| Foresite Capital Management VI LLC | 1,000,000 | $1,651 萬 | 4.99% | 00.0% | 不變 |
| Masters Capital Management LLC | 1,000,000 | $1,651 萬 | 2.28% | +250,000+33.3% | 加碼 |
| Bank of America Corp | 932,144 | $1,539 萬 | 0.00% | −28,994−3.0% | 減碼 |
| Alyeska Investment Group, L.P. | 859,108 | $1,418 萬 | 0.04% | +859,108 | 新進 |
| Citadel Advisors LLC | 779,148 | $1,286 萬 | 0.01% | +90,924+13.2% | 加碼 |
| Marshall Wace, LLP | 763,892 | $1,261 萬 | 0.01% | −23,137−2.9% | 減碼 |
| Bank of New York Mellon Corp | 762,087 | $1,258 萬 | 0.00% | −38,660−4.8% | 減碼 |
| Defilade Capital Management, L.P. | 656,713 | $1,084 萬 | 1.47% | +656,713 | 新進 |
| Palo Alto Investors LP | 641,239 | $1,059 萬 | 1.47% | +233,233+57.2% | 加碼 |
| Cercano Management LLC | 625,000 | $1,032 萬 | 0.39% | 00.0% | 不變 |
| Voloridge Investment Management, LLC | 591,461 | $976.5 萬 | 0.03% | −344,769−36.8% | 減碼 |
| Qube Research & Technologies Ltd | 590,314 | $974.6 萬 | 0.01% | +362,324+158.9% | 加碼 |
| Segall Bryant & Hamill, LLC | 537,000 | $886.6 萬 | 0.12% | +24,042+4.7% | 加碼 |
| Ensign Peak Advisors, Inc | 515,721 | $851.5 萬 | 0.02% | −18,350−3.4% | 減碼 |
| Vestal Point Capital, LP | 465,000 | $767.7 萬 | 0.28% | +465,000 | 新進 |
| Hudson Bay Capital Management LP | 450,000 | $743.0 萬 | 0.04% | +145,000+47.5% | 加碼 |
| Schroder Investment Management Group | 450,985 | $740.1 萬 | 0.01% | +241,390+115.2% | 加碼 |
| Two Sigma Investments, LP | 430,177 | $710.2 萬 | 0.01% | +163,885+61.5% | 加碼 |
| StemPoint Capital LP | 419,058 | $691.9 萬 | 1.19% | −1,315,601−75.8% | 減碼 |
| Barclays PLC | 407,359 | $672.5 萬 | 0.00% | −29,642−6.8% | 減碼 |
| American Century Companies Inc | 379,051 | $625.8 萬 | 0.00% | +21,710+6.1% | 加碼 |
| Millennium Management LLC | 369,767 | $610.5 萬 | 0.00% | −937,404−71.7% | 減碼 |
| Clarius Group, LLC | 368,995 | $609.2 萬 | 0.35% | +9,250+2.6% | 加碼 |
| TD Asset Management Inc | 339,410 | $560.4 萬 | 0.00% | −55,190−14.0% | 減碼 |
| DAFNA Capital Management LLC | 318,500 | $525.8 萬 | 1.22% | +150,000+89.0% | 加碼 |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 298,792 | $493.3 萬 | 0.01% | +297,521+23,408.4% | 加碼 |
| Invesco Ltd. | 291,936 | $482.0 萬 | 0.00% | +42,469+17.0% | 加碼 |
| Marex Group plc | 287,001 | $473.8 萬 | 0.05% | −3,999−1.4% | 減碼 |
| Nuveen, LLC | 275,508 | $454.9 萬 | 0.00% | −9,269−3.3% | 減碼 |
| Swiss National Bank | 273,800 | $452.0 萬 | 0.00% | +6,300+2.4% | 加碼 |
| Edmond de Rothschild Holding S.A. | 225,680 | $372.6 萬 | 0.05% | +20,000+9.7% | 加碼 |
| Trexquant Investment LP | 209,609 | $346.1 萬 | 0.03% | −220,957−51.3% | 減碼 |
| Burkehill Global Management, LP | 200,000 | $330.2 萬 | 0.22% | +200,000 | 新進 |
| SCS Capital Management LLC | 197,998 | $326.9 萬 | 0.03% | 00.0% | 不變 |
| Wells Fargo & Company | 193,681 | $319.8 萬 | 0.00% | +89,502+85.9% | 加碼 |
| Rafferty Asset Management, LLC | 191,567 | $316.3 萬 | 0.01% | +8,681+4.7% | 加碼 |
| Manufacturers Life Insurance Company, The | 184,238 | $303.0 萬 | 0.00% | −21,607−10.5% | 減碼 |
| Rhumbline Advisers | 183,000 | $302.1 萬 | 0.00% | −18,565−9.2% | 減碼 |
| Ameriprise Financial Inc | 180,221 | $297.5 萬 | 0.00% | +80,660+81.0% | 加碼 |
| JPMorgan Chase & Co | 171,948 | $283.9 萬 | 0.00% | −3,073−1.8% | 減碼 |
| Susquehanna Portfolio Strategies, LLC | 167,713 | $276.9 萬 | 0.04% | +167,713 | 新進 |
| Two Sigma Advisers, LP | 154,800 | $255.6 萬 | 0.00% | +64,800+72.0% | 加碼 |
| Teachers Retirement System of the State of Kentucky | 153,781 | $253.9 萬 | 0.02% | −17,772−10.4% | 減碼 |
| Groupama Asset Managment | 151,591 | $250.3 萬 | 0.04% | +15,833+11.7% | 加碼 |
| SG Americas Securities, LLC | 149,592 | $247.0 萬 | 0.00% | +111,391+291.6% | 加碼 |
| Legal & General Group Plc | 131,223 | $216.6 萬 | 0.00% | −12,729−8.8% | 減碼 |
| California State Teachers Retirement System | 129,409 | $213.7 萬 | 0.00% | −117−0.1% | 減碼 |
| Mirae Asset Global ETFs Holdings Ltd. | 128,800 | $212.5 萬 | 0.00% | −1,087−0.8% | 減碼 |
| Algert Global LLC | 127,030 | $209.7 萬 | 0.03% | +25,770+25.4% | 加碼 |
| Alps Advisors Inc | 120,718 | $199.3 萬 | 0.01% | +50,488+71.9% | 加碼 |
| Woodline Partners LP | 114,082 | $188.3 萬 | 0.01% | +565+0.5% | 加碼 |
| B. Metzler seel. Sohn & Co. AG | 112,300 | $184.1 萬 | 0.02% | +112,300 | 新進 |
| Nomura Asset Management International Inc. | 107,493 | $177.5 萬 | 0.00% | +107,493 | 新進 |
| D.A. Davidson & Co. | 106,933 | $176.5 萬 | 0.01% | +106,933 | 新進 |
| Deutsche Bank AG | 105,086 | $173.5 萬 | 0.00% | −102,508−49.4% | 減碼 |
| Rhenman & Partners Asset Management AB | 100,000 | $165.1 萬 | 0.15% | 00.0% | 不變 |
| Ghisallo Capital Management LLC | 100,000 | $165.1 萬 | 0.07% | +100,000 | 新進 |
| Integrated Wealth Concepts LLC | 94,582 | $156.2 萬 | 0.02% | +3,508+3.9% | 加碼 |
| Y-Intercept (Hong Kong) Ltd | 93,587 | $154.5 萬 | 0.03% | +93,587 | 新進 |
| Monashee Investment Management LLC | 91,620 | $151.3 萬 | 0.85% | +91,620 | 新進 |
| DekaBank Deutsche Girozentrale | 59,800 | $135.0 萬 | 0.00% | 00.0% | 不變 |
| HRT Financial LP | 78,352 | $129.3 萬 | 0.00% | +78,352 | 新進 |
| MetLife Investment Management | 75,164 | $124.1 萬 | 0.01% | −3,911−4.9% | 減碼 |
| State of Wisconsin Investment Board | 73,581 | $121.5 萬 | 0.00% | −6,545−8.2% | 減碼 |
| Profund Advisors LLC | 71,634 | $118.3 萬 | 0.04% | +31,478+78.4% | 加碼 |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 70,830 | $116.9 萬 | 0.00% | +44,607+170.1% | 加碼 |
| Ishara Investments LP | 70,000 | $115.6 萬 | 1.35% | +70,000 | 新進 |
| Pier 88 Investment Partners LLC | 68,200 | $112.6 萬 | 0.25% | +760+1.1% | 加碼 |