Denali Therapeutics Inc.
DNLI- 交易所
- Nasdaq
- 產業
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
近 90 天，Denali Therapeutics Inc. 內部人申報 0 筆公開市場買進、4 筆賣出；2026 年第 2 季末有 294 家機構在 13F 申報持有，市值合計 $40.0 億；沒有大師持有。
2025 年第 4 季 13F 持有人
Denali Therapeutics Inc. 在 2025/12/31 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 250
- 較 2025 年第 3 季 +17 家
- 持有股數
- 1.51 億
- 較 2025 年第 3 季 +1,619 萬 (+12.0%)
- 總市值
- $25.0 億
- 較 2025 年第 3 季 +$5.36 億 (+27.4%)
- 新進機構
- 51
- 另有 86 家加碼
- 清倉機構
- 34
- 另有 71 家減碼
另有 7 家機構在 2025 年第 3 季持有、還沒有申報 2025 年第 4 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 DNLI 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 294 | $40.0 億 |
| 2026 年第 1 季 | 269 | $28.2 億 |
| 2025 年第 4 季 | 250 | $25.0 億 |
| 2025 年第 3 季 | 240 | $19.7 億 |
| 2025 年第 2 季 | 231 | $19.3 億 |
| 2025 年第 1 季 | 222 | $18.5 億 |
| 2024 年第 4 季 | 224 | $26.1 億 |
| 2024 年第 3 季 | 217 | $36.9 億 |
| 2024 年第 2 季 | 203 | $28.8 億 |
| 2024 年第 1 季 | 211 | $25.1 億 |
| 2023 年第 4 季 | 209 | $24.7 億 |
| 2023 年第 3 季 | 195 | $22.4 億 |
| 2023 年第 2 季 | 203 | $31.8 億 |
| 2023 年第 1 季 | 202 | $24.9 億 |
| 2022 年第 4 季 | 199 | $29.4 億 |
| 2022 年第 3 季 | 200 | $28.4 億 |
| 2022 年第 2 季 | 188 | $27.3 億 |
| 2022 年第 1 季 | 190 | $27.9 億 |
| 2021 年第 4 季 | 213 | $38.0 億 |
| 2021 年第 3 季 | 214 | $42.8 億 |
| 2021 年第 2 季 | 210 | $63.2 億 |
| 2021 年第 1 季 | 218 | $46.0 億 |
2025 年第 4 季持有機構
每家機構持有 Denali Therapeutics Inc. 的股數、市值與佔組合比重；股數變化跟 2025 年第 3 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| 1492 Capital Management LLC | 67,487 | $111.4 萬 | 0.43% | +67,487 | 新進 |
| Capricorn Fund Managers Ltd | 62,197 | $102.7 萬 | 0.25% | +62,197 | 新進 |
| Creative Planning | 60,766 | $100.3 萬 | 0.00% | +5,932+10.8% | 加碼 |
| Franklin Resources Inc | 60,270 | $99.5 萬 | 0.00% | −4,364−6.8% | 減碼 |
| Janus Henderson Group PLC | 60,028 | $99.1 萬 | 0.00% | 00.0% | 不變 |
| Wellington Management Group LLP | 54,543 | $90.1 萬 | 0.00% | −4,691−7.9% | 減碼 |
| Tudor Investment Corp Et Al | 53,683 | $88.6 萬 | 0.00% | −2,685−4.8% | 減碼 |
| Intech Investment Management LLC | 52,632 | $86.9 萬 | 0.01% | +5,835+12.5% | 加碼 |
| ADAR1 Capital Management, LLC | 52,116 | $86.0 萬 | 0.06% | +600+1.2% | 加碼 |
| Clough Capital Partners L P | 51,830 | $85.6 萬 | 0.08% | +51,830 | 新進 |
| Pathstone Holdings, LLC | 51,424 | $84.9 萬 | 0.00% | +5,594+12.2% | 加碼 |
| Ironwood Investment Management LLC | 50,933 | $84.1 萬 | 0.35% | −1,853−3.5% | 減碼 |
| Dana Investment Advisors, Inc. | 50,582 | $83.5 萬 | 0.02% | −134−0.3% | 減碼 |
| Knights of Columbus Asset Advisors LLC | 49,007 | $80.9 萬 | 0.05% | −1,183−2.4% | 減碼 |
| Man Group plc | 48,994 | $80.9 萬 | 0.00% | +48,994 | 新進 |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 47,459 | $78.4 萬 | 0.00% | 00.0% | 不變 |
| State of New Jersey Common Pension Fund D | 47,410 | $78.3 萬 | 0.00% | −92,253−66.1% | 減碼 |
| Employees Retirement System of Texas | 47,177 | $77.9 萬 | 0.01% | +3,408+7.8% | 加碼 |
| MAI Capital Management | 46,526 | $76.8 萬 | 0.00% | 00.0% | 不變 |
| Headlands Technologies LLC | 46,383 | $76.6 萬 | 0.06% | +46,383 | 新進 |
| Handelsbanken Fonder AB | 43,800 | $72.3 萬 | 0.00% | +5,500+14.4% | 加碼 |
| Jane Street Group, LLC | 42,922 | $70.9 萬 | 0.00% | −181,981−80.9% | 減碼 |
| Quest Partners LLC | 42,909 | $70.8 萬 | 0.04% | −31,513−42.3% | 減碼 |
| Jump Financial, LLC | 40,608 | $67.0 萬 | 0.01% | −125,791−75.6% | 減碼 |
| Savvy Advisors, Inc. | 39,030 | $64.4 萬 | 0.02% | −38,063−49.4% | 減碼 |
| Capstone Investment Advisors, LLC | 38,812 | $64.1 萬 | 0.01% | +38,812 | 新進 |
| Envestnet Asset Management Inc | 38,669 | $63.8 萬 | 0.00% | +6,254+19.3% | 加碼 |
| Arizona State Retirement System | 38,645 | $63.8 萬 | 0.00% | −2,168−5.3% | 減碼 |
| New York State Common Retirement Fund | 38,478 | $63.5 萬 | 0.00% | 00.0% | 不變 |
| AQR Capital Management LLC | 38,438 | $63.5 萬 | 0.00% | +14,299+59.2% | 加碼 |
| Police & Firemen's Retirement System of New Jersey | 36,607 | $60.4 萬 | 0.01% | −56−0.2% | 減碼 |
| Susquehanna International Group, LLP | 34,768 | $57.4 萬 | 0.00% | −6,218−15.2% | 減碼 |
| State Board of Administration of Florida Retirement System | 34,168 | $56.4 萬 | 0.00% | 00.0% | 不變 |
| Thrivent Financial for Lutherans | 32,555 | $53.8 萬 | 0.00% | −3,064−8.6% | 減碼 |
| PSP Research LLC | 31,762 | $52.4 萬 | 0.46% | +31,762 | 新進 |
| Citigroup Inc | 30,945 | $51.1 萬 | 0.00% | +16,009+107.2% | 加碼 |
| ProShare Advisors LLC | 30,682 | $50.7 萬 | 0.00% | +2,827+10.1% | 加碼 |
| KLP Kapitalforvaltning AS | 29,900 | $49.4 萬 | 0.00% | 00.0% | 不變 |
| Erste Asset Management GmbH | 26,900 | $44.6 萬 | 0.00% | 00.0% | 不變 |
| Polen Capital Management LLC | 26,900 | $44.4 萬 | 0.00% | +26,900 | 新進 |
| Quantinno Capital Management LP | 26,313 | $43.4 萬 | 0.00% | +1,606+6.5% | 加碼 |
| Raymond James Financial Inc | 25,592 | $42.3 萬 | 0.00% | +266+1.1% | 加碼 |
| China Universal Asset Management Co., Ltd. | 23,898 | $39.5 萬 | 0.03% | −1,731−6.8% | 減碼 |
| Voya Investment Management LLC | 23,805 | $39.3 萬 | 0.00% | 00.0% | 不變 |
| TT International Asset Management LTD | 27,000 | $35.3 萬 | 0.07% | −38,000−58.5% | 減碼 |
| Teacher Retirement System of Texas | 20,540 | $33.9 萬 | 0.00% | −13,287−39.3% | 減碼 |
| Bayforest Capital Ltd | 20,433 | $33.7 萬 | 0.25% | +20,433 | 新進 |
| Martingale Asset Management L P | 18,535 | $30.6 萬 | 0.01% | +18,535 | 新進 |
| Graham Capital Management, L.P. | 18,121 | $29.9 萬 | 0.01% | −21,198−53.9% | 減碼 |
| SBI Okasan Asset Management Co.Ltd. | 18,000 | $29.8 萬 | 0.02% | +18,000 | 新進 |
| Breakwater Capital Group | 16,366 | $27.0 萬 | 0.04% | +500+3.2% | 加碼 |
| BNP Paribas Arbitrage, SA | 15,497 | $25.6 萬 | 0.00% | −248,564−94.1% | 減碼 |
| Victory Capital Management Inc | 15,064 | $24.9 萬 | 0.00% | 00.0% | 不變 |
| Virtus Investment Advisers, Inc. | 14,795 | $24.4 萬 | 0.07% | +7,171+94.1% | 加碼 |
| Russell Investments Group, Ltd. | 13,467 | $22.2 萬 | 0.00% | −332−2.4% | 減碼 |
| Great West Life Assurance Co | 13,434 | $22.2 萬 | 0.00% | 00.0% | 不變 |
| Tower Research Capital LLC (TRC) | 12,941 | $21.4 萬 | 0.01% | +5,565+75.4% | 加碼 |
| Winton Group Ltd | 12,700 | $21.0 萬 | 0.01% | +12,700 | 新進 |
| Walleye Capital LLC | 12,652 | $20.9 萬 | 0.00% | +12,652 | 新進 |
| Perbak Capital Partners LLP | 12,611 | $20.8 萬 | 0.06% | +12,611 | 新進 |
| Guggenheim Capital LLC | 12,468 | $20.6 萬 | 0.00% | −37,057−74.8% | 減碼 |
| Public Employees Retirement Association of Colorado | 12,238 | $20.2 萬 | 0.00% | 00.0% | 不變 |
| HighTower Advisors, LLC | 11,757 | $19.4 萬 | 0.00% | −9,565−44.9% | 減碼 |
| JustInvest LLC | 11,736 | $19.4 萬 | 0.00% | −790−6.3% | 減碼 |
| Royal Bank of Canada | 11,335 | $18.7 萬 | 0.00% | −360,841−97.0% | 減碼 |
| Empowered Funds, LLC | 11,325 | $18.7 萬 | 0.00% | +288+2.6% | 加碼 |
| Intrust Bank NA | 11,164 | $18.4 萬 | 0.02% | +589+5.6% | 加碼 |
| Ameritas Investment Partners, Inc. | 11,065 | $18.3 萬 | 0.01% | 00.0% | 不變 |
| Renaissance Technologies LLC | 10,700 | $17.7 萬 | 0.00% | −49,100−82.1% | 減碼 |
| LPL Financial LLC | 10,504 | $17.3 萬 | 0.00% | −144−1.4% | 減碼 |
| Xponance, Inc. | 10,497 | $17.3 萬 | 0.00% | +97+0.9% | 加碼 |
| The PNC Financial Services Group, Inc. | 8,481 | $14.0 萬 | 0.00% | +191+2.3% | 加碼 |
| Sterling Capital Management LLC | 7,238 | $11.9 萬 | 0.00% | −1,416−16.4% | 減碼 |
| Bellevue Group AG | 7,138 | $11.8 萬 | 0.00% | +7,138 | 新進 |
| Mirae Asset Global Investments Co., Ltd. | 7,127 | $11.8 萬 | 0.00% | +1,474+26.1% | 加碼 |
| Quarry LP | 7,000 | $11.6 萬 | 0.02% | +2,625+60.0% | 加碼 |
| NBC Securities, Inc. | 6,536 | $10.8 萬 | 0.01% | +6,004+1,128.6% | 加碼 |
| KBC Group NV | 6,268 | $10.3 萬 | 0.00% | +1,773+39.4% | 加碼 |
| Persistent Asset Partners Ltd | 5,670 | $9.36 萬 | 0.05% | +5,670 | 新進 |
| Assetmark, Inc | 5,187 | $8.56 萬 | 0.00% | +1,250+31.8% | 加碼 |
| Eurizon Capital SGR S.p.A. | 5,045 | $8.27 萬 | 0.00% | +5,045 | 新進 |
| Amalgamated Bank | 4,161 | $6.90 萬 | 0.00% | −144−3.3% | 減碼 |
| Aster Capital Management (DIFC) Ltd | 3,451 | $5.70 萬 | 0.02% | +3,451 | 新進 |
| Pinnacle Wealth Planning Services, Inc. | 2,957 | $4.88 萬 | 0.01% | +2,957 | 新進 |
| GF Fund Management Co. Ltd. | 2,881 | $4.76 萬 | 0.00% | −265−8.4% | 減碼 |
| State of Wyoming | 2,686 | $4.43 萬 | 0.00% | +532+24.7% | 加碼 |
| CWM, LLC | 2,606 | $4.30 萬 | 0.00% | +209+8.7% | 加碼 |
| Bartlett & Co. Wealth Management LLC | 1,500 | $2.48 萬 | 0.00% | 00.0% | 不變 |
| Versant Capital Management, Inc | 1,476 | $2.44 萬 | 0.00% | 00.0% | 不變 |
| Nisa Investment Advisors, LLC | 1,449 | $2.39 萬 | 0.00% | −34−2.3% | 減碼 |
| Smartleaf Asset Management LLC | 1,313 | $2.15 萬 | 0.00% | +359+37.6% | 加碼 |
| Comerica Bank | 1,284 | $2.12 萬 | 0.00% | 00.0% | 不變 |
| Rockefeller Capital Management L.P. | 1,265 | $2.09 萬 | 0.00% | +182+16.8% | 加碼 |
| SBI Securities Co., Ltd. | 1,222 | $2.02 萬 | 0.00% | +1,200+5,454.5% | 加碼 |
| Advisor Group Holdings, Inc. | 1,074 | $1.77 萬 | 0.00% | −314−22.6% | 減碼 |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 1,001 | $1.63 萬 | 0.00% | 00.0% | 不變 |
| GAMMA Investing LLC | 962 | $1.59 萬 | 0.00% | +233+32.0% | 加碼 |
| US Bancorp | 834 | $1.38 萬 | 0.00% | +138+19.8% | 加碼 |
| Quadrant Capital Group LLC | 758 | $1.25 萬 | 0.00% | −24−3.1% | 減碼 |
| Nemes Rush Group LLC | 700 | $1.16 萬 | 0.00% | 00.0% | 不變 |