Denali Therapeutics Inc.
DNLI- 交易所
- Nasdaq
- 產業
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
近 90 天，Denali Therapeutics Inc. 內部人申報 0 筆公開市場買進、4 筆賣出；2026 年第 2 季末有 294 家機構在 13F 申報持有，市值合計 $40.0 億；沒有大師持有。
2025 年第 2 季 13F 持有人
Denali Therapeutics Inc. 在 2025/6/30 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 231
- 較 2025 年第 1 季 +10 家
- 持有股數
- 1.38 億
- 較 2025 年第 1 季 +167.2 萬 (+1.2%)
- 總市值
- $19.3 億
- 較 2025 年第 1 季 +$7,607 萬 (+4.1%)
- 新進機構
- 46
- 另有 84 家加碼
- 清倉機構
- 36
- 另有 64 家減碼
另有 1 家機構在 2025 年第 1 季持有、還沒有申報 2025 年第 2 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 DNLI 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 294 | $40.0 億 |
| 2026 年第 1 季 | 269 | $28.2 億 |
| 2025 年第 4 季 | 250 | $25.0 億 |
| 2025 年第 3 季 | 240 | $19.7 億 |
| 2025 年第 2 季 | 231 | $19.3 億 |
| 2025 年第 1 季 | 222 | $18.5 億 |
| 2024 年第 4 季 | 224 | $26.1 億 |
| 2024 年第 3 季 | 217 | $36.9 億 |
| 2024 年第 2 季 | 203 | $28.8 億 |
| 2024 年第 1 季 | 211 | $25.1 億 |
| 2023 年第 4 季 | 209 | $24.7 億 |
| 2023 年第 3 季 | 195 | $22.4 億 |
| 2023 年第 2 季 | 203 | $31.8 億 |
| 2023 年第 1 季 | 202 | $24.9 億 |
| 2022 年第 4 季 | 199 | $29.4 億 |
| 2022 年第 3 季 | 200 | $28.4 億 |
| 2022 年第 2 季 | 188 | $27.3 億 |
| 2022 年第 1 季 | 190 | $27.9 億 |
| 2021 年第 4 季 | 213 | $38.0 億 |
| 2021 年第 3 季 | 214 | $42.8 億 |
| 2021 年第 2 季 | 210 | $63.2 億 |
| 2021 年第 1 季 | 218 | $46.0 億 |
2025 年第 2 季持有機構
每家機構持有 Denali Therapeutics Inc. 的股數、市值與佔組合比重；股數變化跟 2025 年第 1 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| BlackRock, Inc. | 12,053,345 | $1.69 億 | 0.00% | −1,781,611−12.9% | 減碼 |
| Baillie Gifford & Co | 11,955,323 | $1.67 億 | 0.12% | −134,717−1.1% | 減碼 |
| Vanguard Group Inc | 11,810,735 | $1.65 億 | 0.00% | +10,978+0.1% | 加碼 |
| FMR LLC | 7,538,468 | $1.05 億 | 0.01% | +125,114+1.7% | 加碼 |
| Price T Rowe Associates Inc | 6,582,295 | $9,209 萬 | 0.01% | +2,215,061+50.7% | 加碼 |
| UBS Asset Management Americas Inc | 6,262,277 | $8,761 萬 | 0.02% | −504,639−7.5% | 減碼 |
| Wellington Management Group LLP | 5,664,733 | $7,925 萬 | 0.01% | −5,744,865−50.4% | 減碼 |
| Temasek Holdings (Private) Ltd | 5,355,832 | $7,493 萬 | 0.29% | 00.0% | 不變 |
| Capital Research Global Investors | 4,750,579 | $6,646 萬 | 0.01% | −14,558−0.3% | 減碼 |
| State Street Corp | 4,517,994 | $6,321 萬 | 0.00% | +57,237+1.3% | 加碼 |
| Norges Bank | 3,947,387 | $5,522 萬 | 0.01% | +899,781+29.5% | 加碼 |
| Crestline Management, LP | 3,860,732 | $5,401 萬 | 86.33% | −300,000−7.2% | 減碼 |
| Baker Bros. Advisors LP | 3,731,695 | $5,221 萬 | 0.51% | 00.0% | 不變 |
| T. Rowe Price Investment Management, Inc. | 3,246,934 | $4,543 萬 | 0.03% | +3,246,934 | 新進 |
| Geode Capital Management, LLC | 3,172,305 | $4,439 萬 | 0.00% | +135,129+4.4% | 加碼 |
| Alliancebernstein L.P. | 3,137,140 | $4,389 萬 | 0.01% | −17,247−0.5% | 減碼 |
| Dimensional Fund Advisors LP | 2,412,928 | $3,376 萬 | 0.01% | +312,072+14.9% | 加碼 |
| Point72 Asset Management, L.P. | 2,213,947 | $3,097 萬 | 0.07% | +2,213,947 | 新進 |
| Goldman Sachs Group Inc | 1,865,324 | $2,610 萬 | 0.00% | +193,246+11.6% | 加碼 |
| Fisher Asset Management, LLC | 1,515,991 | $2,121 萬 | 0.01% | +151,032+11.1% | 加碼 |
| Marshall Wace, LLP | 1,405,250 | $1,966 萬 | 0.02% | −783,172−35.8% | 減碼 |
| Morgan Stanley | 1,312,016 | $1,836 萬 | 0.00% | +58,413+4.7% | 加碼 |
| Citadel Advisors LLC | 1,248,953 | $1,747 萬 | 0.02% | +79,270+6.8% | 加碼 |
| Northern Trust Corp | 1,201,709 | $1,681 萬 | 0.00% | +69,536+6.1% | 加碼 |
| Principal Financial Group Inc | 1,072,983 | $1,501 萬 | 0.01% | −8,595−0.8% | 減碼 |
| Charles Schwab Investment Management Inc | 1,056,019 | $1,477 萬 | 0.00% | +46,123+4.6% | 加碼 |
| UBS Group AG | 950,764 | $1,330 萬 | 0.00% | +162,335+20.6% | 加碼 |
| Standard Life Aberdeen plc | 902,751 | $1,263 萬 | 0.02% | +142,936+18.8% | 加碼 |
| Millennium Management LLC | 900,501 | $1,260 萬 | 0.01% | −592,567−39.7% | 減碼 |
| Casdin Capital, LLC | 890,000 | $1,245 萬 | 1.13% | −100,000−10.1% | 減碼 |
| Candriam Luxembourg S.C.A. | 844,249 | $1,181 萬 | 0.07% | −13,913−1.6% | 減碼 |
| Siren, L.L.C. | 821,513 | $1,149 萬 | 0.59% | 00.0% | 不變 |
| Bank of New York Mellon Corp | 790,756 | $1,106 萬 | 0.00% | −313,136−28.4% | 減碼 |
| Voloridge Investment Management, LLC | 770,527 | $1,078 萬 | 0.04% | +468,554+155.2% | 加碼 |
| StemPoint Capital LP | 707,915 | $990.4 萬 | 3.19% | +40,837+6.1% | 加碼 |
| Bank of America Corp | 650,222 | $909.7 萬 | 0.00% | +202,465+45.2% | 加碼 |
| Cercano Management LLC | 625,000 | $874.4 萬 | 0.25% | 00.0% | 不變 |
| Masters Capital Management LLC | 600,000 | $839.4 萬 | 1.62% | +600,000 | 新進 |
| Nuveen, LLC | 595,217 | $832.7 萬 | 0.00% | +272,272+84.3% | 加碼 |
| Segall Bryant & Hamill, LLC | 500,559 | $700.3 萬 | 0.10% | +219,420+78.0% | 加碼 |
| TD Asset Management Inc | 496,290 | $694.3 萬 | 0.01% | +187,710+60.8% | 加碼 |
| Ensign Peak Advisors, Inc | 473,695 | $662.7 萬 | 0.01% | −114,090−19.4% | 減碼 |
| Yiheng Capital Management, L.P. | 469,981 | $657.5 萬 | 2.38% | 00.0% | 不變 |
| Barclays PLC | 425,981 | $595.9 萬 | 0.00% | +185,333+77.0% | 加碼 |
| Pictet Asset Management Holding SA | 415,112 | $585.1 萬 | 0.01% | +71,153+20.7% | 加碼 |
| Holocene Advisors, LP | 403,172 | $564.0 萬 | 0.01% | +403,172 | 新進 |
| Camber Capital Management LP | 400,000 | $559.6 萬 | 0.78% | −850,000−68.0% | 減碼 |
| Cubist Systematic Strategies, LLC | 396,586 | $554.8 萬 | 0.06% | +396,586 | 新進 |
| Royal Bank of Canada | 390,155 | $545.9 萬 | 0.00% | +375,719+2,602.7% | 加碼 |
| Schroder Investment Management Group | 386,539 | $540.8 萬 | 0.00% | +94,744+32.5% | 加碼 |
| Clarius Group, LLC | 368,995 | $516.2 萬 | 0.30% | 00.0% | 不變 |
| Edgestream Partners, L.P. | 342,923 | $479.7 萬 | 0.13% | +342,923 | 新進 |
| American Century Companies Inc | 318,193 | $445.2 萬 | 0.00% | −31,227−8.9% | 減碼 |
| Manufacturers Life Insurance Company, The | 315,102 | $440.8 萬 | 0.00% | +56,970+22.1% | 加碼 |
| Pier Capital, LLC | 314,796 | $440.4 萬 | 0.67% | −20,708−6.2% | 減碼 |
| AXA S.A. | 293,853 | $411.1 萬 | 0.01% | +472+0.2% | 加碼 |
| Hudson Bay Capital Management LP | 290,000 | $405.7 萬 | 0.03% | +40,000+16.0% | 加碼 |
| Marex Group plc | 262,000 | $366.5 萬 | 0.07% | +262,000 | 新進 |
| Swiss National Bank | 250,900 | $351.0 萬 | 0.00% | 00.0% | 不變 |
| Palo Alto Investors LP | 239,809 | $335.5 萬 | 0.71% | +239,809 | 新進 |
| Invesco Ltd. | 219,795 | $307.5 萬 | 0.00% | +30,368+16.0% | 加碼 |
| Rhumbline Advisers | 212,503 | $297.3 萬 | 0.00% | +22,247+11.7% | 加碼 |
| Twinbeech Capital LP | 210,370 | $294.3 萬 | 0.07% | +138,348+192.1% | 加碼 |
| Edmond de Rothschild Holding S.A. | 205,680 | $287.7 萬 | 0.05% | 00.0% | 不變 |
| SCS Capital Management LLC | 197,998 | $277.0 萬 | 0.03% | 00.0% | 不變 |
| Renaissance Technologies LLC | 195,700 | $273.8 萬 | 0.00% | +22,600+13.1% | 加碼 |
| JPMorgan Chase & Co | 191,613 | $268.1 萬 | 0.00% | +3,210+1.7% | 加碼 |
| Soleus Capital Management, L.P. | 182,110 | $254.8 萬 | 0.18% | +47,110+34.9% | 加碼 |
| Groupama Asset Managment | 175,531 | $247.5 萬 | 0.04% | +31,043+21.5% | 加碼 |
| Teachers Retirement System of the State of Kentucky | 171,553 | $240.0 萬 | 0.02% | −11,839−6.5% | 減碼 |
| DAFNA Capital Management LLC | 168,500 | $235.7 萬 | 0.65% | +40,600+31.7% | 加碼 |
| Susquehanna International Group, LLP | 161,136 | $225.4 萬 | 0.00% | −6,061−3.6% | 減碼 |
| Campbell & CO Investment Adviser LLC | 142,708 | $199.6 萬 | 0.13% | +74,523+109.3% | 加碼 |
| State of New Jersey Common Pension Fund D | 137,880 | $192.9 萬 | 0.01% | +44,290+47.3% | 加碼 |
| Deutsche Bank AG | 135,969 | $190.2 萬 | 0.00% | −20,283−13.0% | 減碼 |
| Mirae Asset Global ETFs Holdings Ltd. | 134,703 | $188.5 萬 | 0.00% | +46,196+52.2% | 加碼 |
| Legal & General Group Plc | 131,755 | $184.3 萬 | 0.00% | −20,207−13.3% | 減碼 |
| Rafferty Asset Management, LLC | 122,262 | $171.0 萬 | 0.01% | −6,873−5.3% | 減碼 |
| California State Teachers Retirement System | 119,327 | $166.9 萬 | 0.00% | +1,792+1.5% | 加碼 |
| Engineers Gate Manager LP | 116,101 | $162.4 萬 | 0.02% | +98,903+575.1% | 加碼 |
| Woodline Partners LP | 113,517 | $158.8 萬 | 0.01% | 00.0% | 不變 |
| Trexquant Investment LP | 109,242 | $152.8 萬 | 0.02% | −3,982−3.5% | 減碼 |
| Ameriprise Financial Inc | 102,033 | $142.7 萬 | 0.00% | +102,033 | 新進 |
| Rhenman & Partners Asset Management AB | 100,000 | $139.9 萬 | 0.18% | 00.0% | 不變 |
| Savvy Advisors, Inc. | 97,793 | $136.8 萬 | 0.09% | +97,793 | 新進 |
| Integrated Wealth Concepts LLC | 96,046 | $134.4 萬 | 0.01% | +96,046 | 新進 |
| Polar Asset Management Partners Inc. | 91,600 | $128.1 萬 | 0.03% | +70,648+337.2% | 加碼 |
| Wells Fargo & Company | 89,639 | $125.4 萬 | 0.00% | +12,357+16.0% | 加碼 |
| Algert Global LLC | 85,840 | $120.1 萬 | 0.03% | +85,840 | 新進 |
| Jane Street Group, LLC | 85,332 | $119.4 萬 | 0.00% | −128,341−60.1% | 減碼 |
| State of Wisconsin Investment Board | 79,627 | $111.4 萬 | 0.00% | −264−0.3% | 減碼 |
| MetLife Investment Management | 79,075 | $110.6 萬 | 0.01% | +4,310+5.8% | 加碼 |
| Alps Advisors Inc | 78,356 | $109.6 萬 | 0.01% | −33,019−29.6% | 減碼 |
| Citigroup Inc | 76,315 | $106.8 萬 | 0.00% | −117,689−60.7% | 減碼 |
| Intech Investment Management LLC | 71,866 | $100.5 萬 | 0.01% | −5,724−7.4% | 減碼 |
| Man Group plc | 70,028 | $98.0 萬 | 0.00% | −99,357−58.7% | 減碼 |
| Thrivent Financial for Lutherans | 67,917 | $95.0 萬 | 0.00% | 00.0% | 不變 |
| TT International Asset Management LTD | 65,000 | $90.9 萬 | 0.18% | +65,000 | 新進 |
| Graham Capital Management, L.P. | 64,799 | $90.7 萬 | 0.03% | +21,794+50.7% | 加碼 |
| Franklin Resources Inc | 64,525 | $90.3 萬 | 0.00% | −18,723−22.5% | 減碼 |