Denali Therapeutics Inc.
DNLI- 交易所
- Nasdaq
- 產業
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
近 90 天，Denali Therapeutics Inc. 內部人申報 0 筆公開市場買進、4 筆賣出；2026 年第 2 季末有 294 家機構在 13F 申報持有，市值合計 $40.0 億；沒有大師持有。
2026 年第 1 季 13F 持有人
Denali Therapeutics Inc. 在 2026/3/31 季末的機構持股。管理 1 億美元以上美股的機構，每季結束後 45 天內要用 13F 申報多頭部位。13F 是什麼
- 持有機構
- 269
- 較 2025 年第 4 季 +25 家
- 持有股數
- 1.47 億
- 較 2025 年第 4 季 +1,481 萬 (+11.2%)
- 總市值
- $28.2 億
- 較 2025 年第 4 季 +$6.32 億 (+28.8%)
- 新進機構
- 55
- 另有 104 家加碼
- 清倉機構
- 30
- 另有 58 家減碼
另有 6 家機構在 2025 年第 4 季持有、還沒有申報 2026 年第 1 季 13F：沒申報不算清倉，也不計入上面的變化。
歷季持有家數與市值
2021 年第 1 季起，每季在 13F 申報持有 DNLI 的機構家數與合計市值。市值是各季季末的申報市值，也會跟著股價漲跌。
| 季度 | 家數 | 市值 |
|---|---|---|
| 2026 年第 2 季 | 294 | $40.0 億 |
| 2026 年第 1 季 | 269 | $28.2 億 |
| 2025 年第 4 季 | 250 | $25.0 億 |
| 2025 年第 3 季 | 240 | $19.7 億 |
| 2025 年第 2 季 | 231 | $19.3 億 |
| 2025 年第 1 季 | 222 | $18.5 億 |
| 2024 年第 4 季 | 224 | $26.1 億 |
| 2024 年第 3 季 | 217 | $36.9 億 |
| 2024 年第 2 季 | 203 | $28.8 億 |
| 2024 年第 1 季 | 211 | $25.1 億 |
| 2023 年第 4 季 | 209 | $24.7 億 |
| 2023 年第 3 季 | 195 | $22.4 億 |
| 2023 年第 2 季 | 203 | $31.8 億 |
| 2023 年第 1 季 | 202 | $24.9 億 |
| 2022 年第 4 季 | 199 | $29.4 億 |
| 2022 年第 3 季 | 200 | $28.4 億 |
| 2022 年第 2 季 | 188 | $27.3 億 |
| 2022 年第 1 季 | 190 | $27.9 億 |
| 2021 年第 4 季 | 213 | $38.0 億 |
| 2021 年第 3 季 | 214 | $42.8 億 |
| 2021 年第 2 季 | 210 | $63.2 億 |
| 2021 年第 1 季 | 218 | $46.0 億 |
2026 年第 1 季持有機構
每家機構持有 Denali Therapeutics Inc. 的股數、市值與佔組合比重；股數變化跟 2025 年第 4 季比。
| 機構 | 股數 | 市值 | 佔組合 % | 股數變化 | 動作 |
|---|---|---|---|---|---|
| BlackRock, Inc. | 13,034,434 | $2.50 億 | 0.00% | +319,233+2.5% | 加碼 |
| Baillie Gifford & Co | 12,066,479 | $2.32 億 | 0.24% | −244,410−2.0% | 減碼 |
| T. Rowe Price Investment Management, Inc. | 8,519,192 | $1.64 億 | 0.11% | +1,265,060+17.4% | 加碼 |
| Temasek Holdings (Private) Ltd | 7,012,974 | $1.35 億 | 0.45% | 00.0% | 不變 |
| State Street Corp | 6,272,001 | $1.20 億 | 0.00% | +8,630+0.1% | 加碼 |
| Vanguard Capital Management LLC | 6,147,957 | $1.18 億 | 0.00% | +6,147,957 | 新進 |
| Vanguard Portfolio Management LLC | 6,120,160 | $1.18 億 | 0.01% | +6,120,160 | 新進 |
| FMR LLC | 4,575,374 | $8,785 萬 | 0.00% | −1,521,837−25.0% | 減碼 |
| UBS Asset Management Americas Inc | 4,432,314 | $8,510 萬 | 0.02% | −551,412−11.1% | 減碼 |
| Goldman Sachs Group Inc | 4,407,255 | $8,462 萬 | 0.01% | +571,452+14.9% | 加碼 |
| Baker Bros. Advisors LP | 3,731,695 | $7,165 萬 | 0.41% | 00.0% | 不變 |
| Geode Capital Management, LLC | 3,727,114 | $7,158 萬 | 0.00% | +268,983+7.8% | 加碼 |
| Holocene Advisors, LP | 3,195,429 | $6,135 萬 | 0.15% | +42,695+1.4% | 加碼 |
| Dimensional Fund Advisors LP | 2,692,175 | $5,169 萬 | 0.01% | +317,872+13.4% | 加碼 |
| UBS Group AG | 2,571,344 | $4,937 萬 | 0.01% | +166,640+6.9% | 加碼 |
| Pictet Asset Management Holding SA | 2,558,865 | $4,844 萬 | 0.05% | +1,229,757+92.5% | 加碼 |
| Capital Research Global Investors | 2,514,588 | $4,828 萬 | 0.01% | −1,214,656−32.6% | 減碼 |
| Alliancebernstein L.P. | 2,893,618 | $4,777 萬 | 0.02% | −664,317−18.7% | 減碼 |
| Price T Rowe Associates Inc | 2,464,146 | $4,731 萬 | 0.01% | −1,451,805−37.1% | 減碼 |
| Fisher Asset Management, LLC | 2,436,895 | $4,679 萬 | 0.02% | −152,508−5.9% | 減碼 |
| Crestline Management, LP | 2,210,732 | $4,245 萬 | 91.74% | −600,000−21.3% | 減碼 |
| Alyeska Investment Group, L.P. | 1,941,123 | $3,727 萬 | 0.11% | +1,082,015+125.9% | 加碼 |
| Lynx1 Capital Management LP | 1,880,303 | $3,610 萬 | 5.71% | +141,553+8.1% | 加碼 |
| ADAR1 Capital Management, LLC | 1,871,455 | $3,593 萬 | 2.16% | +1,819,339+3,490.9% | 加碼 |
| Standard Life Aberdeen plc | 1,854,446 | $3,561 萬 | 0.06% | −178,521−8.8% | 減碼 |
| Casdin Capital, LLC | 1,840,000 | $3,533 萬 | 2.68% | 00.0% | 不變 |
| Vestal Point Capital, LP | 1,773,326 | $3,405 萬 | 0.95% | +1,308,326+281.4% | 加碼 |
| Principal Financial Group Inc | 1,478,486 | $2,839 萬 | 0.02% | −45,637−3.0% | 減碼 |
| Siren, L.L.C. | 1,396,513 | $2,681 萬 | 0.74% | 00.0% | 不變 |
| Defilade Capital Management, L.P. | 1,359,969 | $2,611 萬 | 3.67% | +703,256+107.1% | 加碼 |
| Northern Trust Corp | 1,310,656 | $2,516 萬 | 0.00% | +110,912+9.2% | 加碼 |
| Millennium Management LLC | 1,257,950 | $2,415 萬 | 0.02% | +888,183+240.2% | 加碼 |
| Foresite Capital Management VI LLC | 1,209,971 | $2,323 萬 | 5.05% | +209,971+21.0% | 加碼 |
| Charles Schwab Investment Management Inc | 1,207,399 | $2,318 萬 | 0.00% | +6,924+0.6% | 加碼 |
| Bank of America Corp | 1,134,183 | $2,178 萬 | 0.00% | +202,039+21.7% | 加碼 |
| Morgan Stanley | 1,104,757 | $2,121 萬 | 0.00% | −115,097−9.4% | 減碼 |
| Candriam Luxembourg S.C.A. | 1,099,845 | $2,112 萬 | 0.11% | −66,534−5.7% | 減碼 |
| Artisan Partners Limited Partnership | 1,099,719 | $2,111 萬 | 0.03% | +1,099,719 | 新進 |
| Marshall Wace, LLP | 991,268 | $1,903 萬 | 0.02% | +227,376+29.8% | 加碼 |
| Vanguard Fiduciary Trust Co | 949,695 | $1,823 萬 | 0.00% | +949,695 | 新進 |
| American Century Companies Inc | 935,692 | $1,797 萬 | 0.01% | +556,641+146.9% | 加碼 |
| Bank of New York Mellon Corp | 768,039 | $1,475 萬 | 0.00% | +5,952+0.8% | 加碼 |
| Clearstead Advisors, LLC | 737,990 | $1,417 萬 | 0.13% | +737,990 | 新進 |
| Cercano Management LLC | 625,000 | $1,200 萬 | 0.52% | 00.0% | 不變 |
| Masters Capital Management LLC | 600,000 | $1,152 萬 | 1.70% | −400,000−40.0% | 減碼 |
| Ensign Peak Advisors, Inc | 515,721 | $990.2 萬 | 0.02% | 00.0% | 不變 |
| Segall Bryant & Hamill, LLC | 510,543 | $980.2 萬 | 0.14% | −26,457−4.9% | 減碼 |
| StemPoint Capital LP | 426,561 | $819.0 萬 | 1.57% | +7,503+1.8% | 加碼 |
| Woodline Partners LP | 364,082 | $699.0 萬 | 0.03% | +250,000+219.1% | 加碼 |
| Hudson Bay Capital Management LP | 346,360 | $665.0 萬 | 0.04% | −103,640−23.0% | 減碼 |
| DAFNA Capital Management LLC | 318,500 | $611.5 萬 | 1.39% | 00.0% | 不變 |
| Invesco Ltd. | 310,196 | $595.6 萬 | 0.00% | +18,260+6.3% | 加碼 |
| JPMorgan Chase & Co | 323,989 | $585.8 萬 | 0.00% | +152,041+88.4% | 加碼 |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 296,503 | $569.3 萬 | 0.01% | −2,289−0.8% | 減碼 |
| Braidwell LP | 296,324 | $568.9 萬 | 0.19% | +296,324 | 新進 |
| Nuveen, LLC | 295,586 | $567.5 萬 | 0.00% | +20,078+7.3% | 加碼 |
| Marex Group plc | 287,000 | $551.0 萬 | 0.06% | −10.0% | 減碼 |
| Swiss National Bank | 273,800 | $525.7 萬 | 0.00% | 00.0% | 不變 |
| Schroder Investment Management Group | 285,820 | $516.8 萬 | 0.00% | −165,165−36.6% | 減碼 |
| TD Asset Management Inc | 255,766 | $491.1 萬 | 0.00% | −83,644−24.6% | 減碼 |
| Privium Fund Management B.V. | 254,857 | $489.3 萬 | 1.02% | +254,857 | 新進 |
| Palo Alto Investors LP | 234,582 | $450.4 萬 | 0.69% | −406,657−63.4% | 減碼 |
| Great Lakes Advisors, LLC | 227,110 | $436.1 萬 | 0.04% | +227,110 | 新進 |
| Edmond de Rothschild Holding S.A. | 225,680 | $433.3 萬 | 0.06% | 00.0% | 不變 |
| Groupama Asset Managment | 207,130 | $397.7 萬 | 0.06% | +55,539+36.6% | 加碼 |
| Burkehill Global Management, LP | 200,000 | $384.0 萬 | 0.19% | 00.0% | 不變 |
| Rhenman & Partners Asset Management AB | 199,000 | $382.1 萬 | 0.47% | +99,000+99.0% | 加碼 |
| SCS Capital Management LLC | 197,998 | $380.2 萬 | 0.04% | 00.0% | 不變 |
| Balyasny Asset Management LLC | 195,108 | $374.6 萬 | 0.01% | +195,108 | 新進 |
| Rhumbline Advisers | 184,248 | $353.8 萬 | 0.00% | +1,248+0.7% | 加碼 |
| Citadel Advisors LLC | 181,417 | $348.3 萬 | 0.00% | −597,731−76.7% | 減碼 |
| Teachers Retirement System of the State of Kentucky | 166,181 | $319.0 萬 | 0.02% | +12,400+8.1% | 加碼 |
| Sector Gamma AS | 162,710 | $312.4 萬 | 0.74% | +162,710 | 新進 |
| California State Teachers Retirement System | 162,576 | $312.1 萬 | 0.00% | +33,167+25.6% | 加碼 |
| Susquehanna Portfolio Strategies, LLC | 157,896 | $303.2 萬 | 0.05% | −9,817−5.9% | 減碼 |
| Rafferty Asset Management, LLC | 150,687 | $289.3 萬 | 0.01% | −40,880−21.3% | 減碼 |
| Man Group plc | 139,045 | $267.0 萬 | 0.01% | +90,051+183.8% | 加碼 |
| Alps Advisors Inc | 129,105 | $247.9 萬 | 0.01% | +8,387+6.9% | 加碼 |
| New York State Common Retirement Fund | 128,119 | $246.0 萬 | 0.00% | +89,641+233.0% | 加碼 |
| Manufacturers Life Insurance Company, The | 125,442 | $240.8 萬 | 0.00% | −58,796−31.9% | 減碼 |
| Vanguard Asset Management, Ltd | 125,243 | $240.5 萬 | 0.00% | +125,243 | 新進 |
| Deutsche Bank AG | 120,368 | $231.1 萬 | 0.00% | +15,282+14.5% | 加碼 |
| Nomura Asset Management International Inc. | 114,524 | $219.9 萬 | 0.00% | +7,031+6.5% | 加碼 |
| B. Metzler seel. Sohn & Co. AG | 112,300 | $215.6 萬 | 0.02% | 00.0% | 不變 |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 111,694 | $214.5 萬 | 0.00% | +64,235+135.3% | 加碼 |
| Legal & General Group Plc | 110,250 | $211.7 萬 | 0.00% | −20,973−16.0% | 減碼 |
| D.A. Davidson & Co. | 110,235 | $211.7 萬 | 0.01% | +3,302+3.1% | 加碼 |
| Wells Fargo & Company | 107,657 | $206.7 萬 | 0.00% | −86,024−44.4% | 減碼 |
| AQR Capital Management LLC | 102,579 | $197.0 萬 | 0.00% | +64,141+166.9% | 加碼 |
| Ghisallo Capital Management LLC | 100,000 | $192.0 萬 | 0.05% | 00.0% | 不變 |
| Integrated Wealth Concepts LLC | 99,554 | $191.1 萬 | 0.02% | +4,972+5.3% | 加碼 |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 99,503 | $191.0 萬 | 0.00% | +28,673+40.5% | 加碼 |
| Lumbard & Kellner, LLC | 94,782 | $182.0 萬 | 0.63% | +94,782 | 新進 |
| Mirae Asset Global ETFs Holdings Ltd. | 95,193 | $181.6 萬 | 0.00% | −33,607−26.1% | 減碼 |
| Ameriprise Financial Inc | 89,534 | $171.9 萬 | 0.00% | −90,687−50.3% | 減碼 |
| State of Wisconsin Investment Board | 82,357 | $158.1 萬 | 0.00% | +8,776+11.9% | 加碼 |
| XTX Topco Ltd | 78,567 | $150.8 萬 | 0.03% | +78,567 | 新進 |
| Y-Intercept (Hong Kong) Ltd | 78,007 | $149.8 萬 | 0.03% | −15,580−16.6% | 減碼 |
| MetLife Investment Management | 77,558 | $148.9 萬 | 0.01% | +2,394+3.2% | 加碼 |
| Creative Planning | 74,069 | $142.2 萬 | 0.00% | +13,303+21.9% | 加碼 |