Denali Therapeutics Inc.
DNLI- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001714899
In the last 90 days, Denali Therapeutics Inc. insiders filed 0 open-market purchases and 4 sales; 294 institutions reported holding it in 13F filings for Q2 2026, worth $4.00B in total; no superinvestor holds it.
13F holders, Q2 2026
Institutional positions in Denali Therapeutics Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 294
- +28 vs. Q1 2026
- Shares held
- 156.2M
- +8.88M (+6.0%) vs. Q1 2026
- Total value
- $4.00B
- +$1.18B (+41.8%) vs. Q1 2026
- New holders
- 56
- 120 more added
- Sold out
- 28
- 68 more reduced
3 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DNLI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 294 | $4.00B |
| Q1 2026 | 269 | $2.82B |
| Q4 2025 | 250 | $2.50B |
| Q3 2025 | 240 | $1.97B |
| Q2 2025 | 231 | $1.93B |
| Q1 2025 | 222 | $1.85B |
| Q4 2024 | 224 | $2.61B |
| Q3 2024 | 217 | $3.69B |
| Q2 2024 | 203 | $2.88B |
| Q1 2024 | 211 | $2.51B |
| Q4 2023 | 209 | $2.47B |
| Q3 2023 | 195 | $2.24B |
| Q2 2023 | 203 | $3.18B |
| Q1 2023 | 202 | $2.49B |
| Q4 2022 | 199 | $2.94B |
| Q3 2022 | 200 | $2.84B |
| Q2 2022 | 188 | $2.73B |
| Q1 2022 | 190 | $2.79B |
| Q4 2021 | 213 | $3.80B |
| Q3 2021 | 214 | $4.28B |
| Q2 2021 | 210 | $6.32B |
| Q1 2021 | 218 | $4.60B |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Denali Therapeutics Inc.; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Letko, Brosseau & Associates Inc | 7,850 | $201.9K | 0.00% | +7,850 | New |
| Fox Run Management, L.L.C. | 7,779 | $200.1K | 0.03% | +7,779 | New |
| Mirae Asset Global Investments Co., Ltd. | 7,098 | $182.6K | 0.00% | −1,174−14.2% | Reduced |
| Acadian Asset Management LLC | 6,476 | $166.0K | 0.00% | +6,476 | New |
| Assetmark, Inc | 5,216 | $134.2K | 0.00% | +17+0.3% | Added |
| Eurizon Capital SGR S.p.A. | 5,045 | $130.7K | 0.00% | 00.0% | Unchanged |
| KBC Group NV | 4,943 | $127.0K | 0.00% | 00.0% | Unchanged |
| STRS Ohio | 4,300 | $110.6K | 0.00% | +4,300 | New |
| Nisa Investment Advisors, LLC | 3,697 | $95.1K | 0.00% | +1,273+52.5% | Added |
| GF Fund Management Co. Ltd. | 3,357 | $86.3K | 0.00% | +63+1.9% | Added |
| Fifth Third Bancorp | 3,019 | $77.7K | 0.00% | +172+6.0% | Added |
| Sterling Capital Management LLC | 2,837 | $73.0K | 0.00% | −1,656−36.9% | Reduced |
| Graticule Asia Macro Advisors LLC | 2,206 | $56.7K | 0.00% | +2,206 | New |
| Allworth Financial LP | 1,834 | $47.2K | 0.00% | +1,554+555.0% | Added |
| SRS Capital Advisors, Inc. | 1,661 | $42.7K | 0.00% | +1,360+451.8% | Added |
| Versant Capital Management, Inc | 1,633 | $42.0K | 0.00% | +157+10.6% | Added |
| Pacer Advisors, Inc. | 1,609 | $41.0K | 0.00% | +1,609 | New |
| GAMMA Investing LLC | 1,549 | $39.8K | 0.00% | +121+8.5% | Added |
| Bartlett & Co. Wealth Management LLC | 1,500 | $38.6K | 0.00% | 00.0% | Unchanged |
| Nykredit A/S | 1,488 | $38.3K | 0.00% | +1,488 | New |
| SBI Securities Co., Ltd. | 1,448 | $37.2K | 0.00% | +1,080+293.5% | Added |
| Kemnay Advisory Services Inc. | 1,304 | $33.5K | 0.00% | +170+15.0% | Added |
| Smartleaf Asset Management LLC | 1,107 | $28.7K | 0.00% | 00.0% | Unchanged |
| Global Retirement Partners, LLC | 1,103 | $28.4K | 0.00% | +1,103 | New |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 1,001 | $25.7K | 0.00% | 00.0% | Unchanged |
| US Bancorp | 950 | $24.4K | 0.00% | +48+5.3% | Added |
| NBC Securities, Inc. | 938 | $24.1K | 0.00% | −6,679−87.7% | Reduced |
| Optiver Holding B.V. | 776 | $20.0K | 0.00% | −90−10.4% | Reduced |
| Group One Trading, L.P. | 776 | $20.0K | 0.00% | +776 | New |
| Nemes Rush Group LLC | 700 | $18.0K | 0.00% | 00.0% | Unchanged |
| Los Angeles Capital Management LLC | 627 | $16.1K | 0.00% | −300−32.4% | Reduced |
| Umb Bank N A | 624 | $16.0K | 0.00% | 00.0% | Unchanged |
| Mowery & Schoenfeld Wealth Management, LLC | 555 | $14.3K | 0.02% | +55+11.0% | Added |
| Farther Finance Advisors, LLC | 537 | $13.8K | 0.00% | +282+110.6% | Added |
| IFP Advisors, Inc | 503 | $12.9K | 0.00% | +494+5,488.9% | Added |
| Owl Creek Wealth Partners LLC | 450 | $11.6K | 0.00% | 00.0% | Unchanged |
| Huntington National Bank | 445 | $11.4K | 0.00% | +25+6.0% | Added |
| Rothschild Investment LLC | 437 | $11.2K | 0.00% | +149+51.7% | Added |
| Covestor Ltd | 347 | $9.00K | 0.01% | +25+7.8% | Added |
| Steward Partners Investment Advisory, LLC | 340 | $8.74K | 0.00% | +204+150.0% | Added |
| Private Wealth Management Group, LLC | 296 | $7.61K | 0.00% | 00.0% | Unchanged |
| City State Bank | 250 | $6.43K | 0.00% | 00.0% | Unchanged |
| Essential Partners LLC | 236 | $6.07K | 0.00% | +191+424.4% | Added |
| Signaturefd, LLC | 230 | $5.92K | 0.00% | −11−4.6% | Reduced |
| SJS Investment Consulting Inc. | 218 | $5.61K | 0.00% | +202+1,262.5% | Added |
| EverSource Wealth Advisors, LLC | 213 | $5.48K | 0.00% | −43−16.8% | Reduced |
| Parallel Advisors, LLC | 213 | $5.48K | 0.00% | −145−40.5% | Reduced |
| Comprehensive Financial Planning, Inc. | 200 | $5.14K | 0.00% | 00.0% | Unchanged |
| HM Payson & Co | 200 | $5.14K | 0.00% | +200 | New |
| Parkside Financial Bank & Trust | 189 | $4.86K | 0.00% | 00.0% | Unchanged |
| Massmutual Trust Co FSB | 143 | $3.68K | 0.00% | 00.0% | Unchanged |
| WPG Advisers, LLC | 142 | $3.65K | 0.00% | +76+115.2% | Added |
| Meeder Asset Management Inc | 142 | $3.65K | 0.00% | +142 | New |
| Ameriflex Group, Inc. | 104 | $2.67K | 0.00% | +104 | New |
| Jones Financial Companies LLLP | 104 | $2.66K | 0.00% | +65+166.7% | Added |
| True Wealth Design, LLC | 88 | $2.26K | 0.00% | +31+54.4% | Added |
| CVA Family Office, LLC | 86 | $2.21K | 0.00% | +23+36.5% | Added |
| Johnson Financial Group, Inc. | 81 | $2.08K | 0.00% | 00.0% | Unchanged |
| UMA Financial Services, Inc. | 76 | $1.96K | 0.00% | 00.0% | Unchanged |
| TD Private Client Wealth LLC | 71 | $1.83K | 0.00% | 00.0% | Unchanged |
| Rossby Financial, LCC | 65 | $1.67K | 0.00% | 00.0% | Unchanged |
| Wealth Enhancement Trust Services, Inc. | 65 | $1.67K | 0.00% | +65 | New |
| Clearstead Advisors, LLC | 62 | $1.59K | 0.00% | −737,928−100.0% | Reduced |
| Fortitude Family Office, LLC | 61 | $1.57K | 0.00% | +26+74.3% | Added |
| JFS Wealth Advisors, LLC | 51 | $1.31K | 0.00% | +43+537.5% | Added |
| Caitong International Asset Management Co., Ltd | 46 | $1.18K | 0.00% | −15,815−99.7% | Reduced |
| Ronald Blue Trust, Inc. | 40 | $1.03K | 0.00% | 00.0% | Unchanged |
| Transamerica Financial Advisors, Inc. | 40 | $1.03K | 0.00% | 00.0% | Unchanged |
| Hantz Financial Services, Inc. | 57 | $1.00K | 0.00% | 00.0% | Unchanged |
| Avion Wealth | 40 | $1.00K | 0.00% | 00.0% | Unchanged |
| Bell Investment Advisors, Inc | 38 | $978 | 0.00% | 00.0% | Unchanged |
| Larson Financial Group LLC | 38 | $977 | 0.00% | −24−38.7% | Reduced |
| Manchester Capital Management LLC | 36 | $926 | 0.00% | 00.0% | Unchanged |
| Cornerstone Financial Management LLC | 34 | $874 | 0.00% | 00.0% | Unchanged |
| Action Point Financial Planning, LLC | 33 | $849 | 0.00% | +33 | New |
| Keating Financial Advisory Services, Inc. | 27 | $694 | 0.00% | −6−18.2% | Reduced |
| Bear Mountain Capital, Inc. | 22 | $494 | 0.00% | +22 | New |
| Creative Capital Management Investments LLC | 18 | $463 | 0.00% | +18 | New |
| Basecamp Wealth Advisors LLC | 17 | $437 | 0.00% | 00.0% | Unchanged |
| HFM Investment Advisors, LLC | 11 | $283 | 0.00% | +6+120.0% | Added |
| DiNuzzo Private Wealth, Inc. | 10 | $258 | 0.00% | +8+400.0% | Added |
| Cullen/Frost Bankers, Inc. | 10 | $257 | 0.00% | 00.0% | Unchanged |
| Atlantic Private Wealth, LLC | 10 | $257 | 0.00% | 00.0% | Unchanged |
| Rialto Wealth Management, LLC | 7 | $181 | 0.00% | +2+40.0% | Added |
| Bay Harbor Wealth Management, LLC | 7 | $180 | 0.00% | +1+16.7% | Added |
| LRI Investments, LLC | 3 | $77 | 0.00% | +3 | New |
| Dunhill Financial, LLC | 2 | $53 | 0.00% | 00.0% | Unchanged |
| DecisionPoint Financial, LLC | 2 | $52 | 0.00% | +2 | New |
| JPL Wealth Management, LLC | 2 | $52 | 0.00% | +2 | New |
| Raffa Wealth Management, LLC | 1 | $26 | 0.00% | 00.0% | Unchanged |
| Northwestern Mutual Wealth Management Co | 1 | $26 | 0.00% | +1 | New |
| Maryland Capital Advisors Inc. | 1 | $26 | 0.00% | +1 | New |
| Silver Grove Financial Group, Inc. | 1 | $26 | 0.00% | +1 | New |
| Navigoe, LLC | 3 | $0 | 0.00% | +3 | New |
| Vestal Point Capital, LP | 0 | $0 | 0.00% | −1,773,326−100.0% | Sold out |
| StemPoint Capital LP | 0 | $0 | 0.00% | −426,561−100.0% | Sold out |
| Braidwell LP | 0 | $0 | 0.00% | −296,324−100.0% | Sold out |
| Schroder Investment Management Group | 0 | $0 | 0.00% | −285,820−100.0% | Sold out |
| Palo Alto Investors LP | 0 | $0 | 0.00% | −234,582−100.0% | Sold out |
| Balyasny Asset Management LLC | 0 | $0 | 0.00% | −195,108−100.0% | Sold out |