Xenon Pharmaceuticals Inc.
XENE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001582313
In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q2 2026
Institutional positions in Xenon Pharmaceuticals Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 315
- +27 vs. Q1 2026
- Shares held
- 101.1M
- +5.07M (+5.3%) vs. Q1 2026
- Total value
- $6.10B
- +$538.5M (+9.7%) vs. Q1 2026
- New holders
- 49
- 126 more added
- Sold out
- 22
- 87 more reduced
2 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2026: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 315 | $6.10B |
| Q1 2026 | 290 | $5.80B |
| Q4 2025 | 245 | $3.78B |
| Q3 2025 | 219 | $3.39B |
| Q2 2025 | 206 | $2.60B |
| Q1 2025 | 206 | $2.58B |
| Q4 2024 | 209 | $2.99B |
| Q3 2024 | 203 | $2.95B |
| Q2 2024 | 213 | $2.89B |
| Q1 2024 | 220 | $3.16B |
| Q4 2023 | 204 | $3.32B |
| Q3 2023 | 181 | $2.10B |
| Q2 2023 | 175 | $2.36B |
| Q1 2023 | 163 | $2.19B |
| Q4 2022 | 159 | $2.38B |
| Q3 2022 | 154 | $2.09B |
| Q2 2022 | 151 | $1.73B |
| Q1 2022 | 132 | $1.50B |
| Q4 2021 | 130 | $1.49B |
| Q3 2021 | 118 | $521.7M |
| Q2 2021 | 103 | $620.0M |
| Q1 2021 | 91 | $590.0M |
Institutions, Q2 2026
Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| ExodusPoint Capital Management, LP | 84,591 | $5.11M | 0.05% | −88,834−51.2% | Reduced |
| Royal Bank of Canada | 84,971 | $5.13M | 0.00% | −5,416−6.0% | Reduced |
| Raymond James Financial Inc | 86,461 | $5.22M | 0.00% | −2,137−2.4% | Reduced |
| Citigroup Inc | 92,124 | $5.56M | 0.00% | +79,973+658.2% | Added |
| California State Teachers Retirement System | 92,740 | $5.60M | 0.01% | −70.0% | Reduced |
| Vanguard Fiduciary Trust Co | 92,878 | $5.61M | 0.00% | +17,761+23.6% | Added |
| Alps Advisors Inc | 97,610 | $5.89M | 0.03% | +29,887+44.1% | Added |
| Burkehill Global Management, LP | 100,000 | $6.04M | 0.22% | 00.0% | Unchanged |
| Sphera Funds Management Ltd. | 105,000 | $6.34M | 0.91% | −22,000−17.3% | Reduced |
| Axiom Investors LLC | 108,238 | $6.53M | 0.06% | +8,670+8.7% | Added |
| Mutual of America Capital Management LLC | 109,603 | $6.62M | 0.06% | −5,991−5.2% | Reduced |
| Squarepoint Ops LLC | 112,869 | $6.81M | 0.01% | +112,869 | New |
| SEI Investments Co | 119,251 | $7.20M | 0.01% | +4,870+4.3% | Added |
| Schroder Investment Management Group | 121,819 | $7.32M | 0.01% | +40,663+50.1% | Added |
| Rhumbline Advisers | 123,398 | $7.45M | 0.01% | +21,613+21.2% | Added |
| KBC Group NV | 129,010 | $7.79M | 0.02% | 00.0% | Unchanged |
| Granahan Investment Management Inc | 129,443 | $7.81M | 0.28% | +24,965+23.9% | Added |
| Point72 Asset Management, L.P. | 130,378 | $7.87M | 0.01% | +130,378 | New |
| Susquehanna Portfolio Strategies, LLC | 133,059 | $8.03M | 0.13% | +114,591+620.5% | Added |
| HSBC Holdings PLC | 151,474 | $9.14M | 0.00% | +29,916+24.6% | Added |
| Russell Investments Group, Ltd. | 153,227 | $9.25M | 0.01% | +23,828+18.4% | Added |
| Woodline Partners LP | 155,302 | $9.37M | 0.03% | +5,000+3.3% | Added |
| Foresite Capital Management IV, LLC | 160,000 | $9.66M | 3.33% | 00.0% | Unchanged |
| Swiss National Bank | 162,700 | $9.82M | 0.01% | +5,000+3.2% | Added |
| Peregrine Capital Management LLC | 164,894 | $9.95M | 0.32% | +21,758+15.2% | Added |
| ADAR1 Capital Management, LLC | 166,550 | $10.1M | 0.47% | −62,349−27.2% | Reduced |
| Wells Fargo & Company | 173,945 | $10.5M | 0.00% | +58,293+50.4% | Added |
| NEXTBio Capital Management LP | 183,225 | $11.1M | 5.09% | 00.0% | Unchanged |
| Boothbay Fund Management, LLC | 183,343 | $11.1M | 0.21% | −87,069−32.2% | Reduced |
| Silverarc Capital Management, LLC | 186,821 | $11.3M | 1.26% | −10,938−5.5% | Reduced |
| Renaissance Technologies LLC | 187,110 | $11.3M | 0.02% | −113,390−37.7% | Reduced |
| Deutsche Bank AG | 191,126 | $11.5M | 0.00% | +28,444+17.5% | Added |
| Balyasny Asset Management LLC | 193,407 | $11.7M | 0.02% | −40,498−17.3% | Reduced |
| Eversept Partners, LP | 196,532 | $11.9M | 0.65% | +66,958+51.7% | Added |
| Integral Health Asset Management, LLC | 200,000 | $12.1M | 0.50% | 00.0% | Unchanged |
| DnB Asset Management AS | 200,451 | $12.1M | 0.03% | +19,366+10.7% | Added |
| Trexquant Investment LP | 202,455 | $12.2M | 0.08% | +135,094+200.6% | Added |
| Neuberger Berman Group LLC | 206,604 | $12.5M | 0.01% | +76,166+58.4% | Added |
| Jennison Associates LLC | 208,060 | $12.6M | 0.01% | −1,110,754−84.2% | Reduced |
| New York State Common Retirement Fund | 210,471 | $12.7M | 0.02% | +21,966+11.7% | Added |
| Patient Square Capital LP | 220,000 | $13.3M | 2.06% | −7,000−3.1% | Reduced |
| D. E. Shaw & Co., Inc. | 223,922 | $13.5M | 0.01% | +204,982+1,082.3% | Added |
| Schonfeld Strategic Advisors LLC | 227,330 | $13.7M | 0.07% | −97,392−30.0% | Reduced |
| Redmile Group, LLC | 229,374 | $13.8M | 0.93% | −33,300−12.7% | Reduced |
| Allspring Global Investments Holdings, LLC | 234,412 | $14.1M | 0.02% | −11,894−4.8% | Reduced |
| Duquesne Family Office LLCSuperinvestorDuquesne Family Office | 238,600 | $14.4M | 0.33% | 00.0% | Unchanged |
| Nan Fung Trinity (HK) Ltd | 247,765 | $15.0M | 1.48% | 00.0% | Unchanged |
| State of Wisconsin Investment Board | 248,821 | $15.0M | 0.03% | −5,662−2.2% | Reduced |
| Charles Schwab Investment Management Inc | 249,473 | $15.1M | 0.00% | +60,393+31.9% | Added |
| DAFNA Capital Management LLC | 250,772 | $15.1M | 2.89% | 00.0% | Unchanged |
| Jump Financial, LLC | 260,730 | $15.7M | 0.14% | +104,954+67.4% | Added |
| Soleus Capital Management, L.P. | 267,000 | $16.1M | 0.56% | −25,000−8.6% | Reduced |
| Adage Capital Partners GP, L.L.C. | 300,000 | $18.1M | 0.03% | −170,000−36.2% | Reduced |
| Man Group plc | 310,617 | $18.7M | 0.03% | +310,617 | New |
| Ameriprise Financial Inc | 318,548 | $19.2M | 0.00% | +239,643+303.7% | Added |
| Jones Hill Capital LP | 367,900 | $22.2M | 4.72% | +367,900 | New |
| Baker Bros. Advisors LP | 370,208 | $22.3M | 0.11% | 00.0% | Unchanged |
| UBS Asset Management Americas Inc | 374,748 | $22.6M | 0.00% | −418−0.1% | Reduced |
| Millennium Management LLC | 376,777 | $22.7M | 0.02% | +174,992+86.7% | Added |
| Nicholas Investment Partners, LP | 395,844 | $23.9M | 1.35% | +148,743+60.2% | Added |
| Parkman Healthcare Partners LLC | 397,379 | $24.0M | 2.46% | −99,656−20.1% | Reduced |
| Bank of America Corp | 404,067 | $24.4M | 0.00% | +138,800+52.3% | Added |
| Fiera Capital Corp | 405,638 | $24.5M | 0.09% | −303,891−42.8% | Reduced |
| Morgan Stanley | 406,257 | $24.5M | 0.00% | −67,502−14.2% | Reduced |
| Standard Life Aberdeen plc | 408,736 | $24.7M | 0.03% | −201,193−33.0% | Reduced |
| Algert Global LLC | 419,773 | $25.3M | 0.30% | +155,573+58.9% | Added |
| Bank of New York Mellon Corp | 421,518 | $25.4M | 0.00% | +25,380+6.4% | Added |
| Trails Edge Capital Partners, LP | 440,000 | $26.6M | 4.22% | 00.0% | Unchanged |
| Logos Global Management LP | 450,000 | $27.2M | 1.17% | 00.0% | Unchanged |
| TimesSquare Capital Management, LLC | 451,593 | $27.3M | 0.40% | +92,300+25.7% | Added |
| Candriam Luxembourg S.C.A. | 462,768 | $27.9M | 0.13% | −13,726−2.9% | Reduced |
| Novo Holdings A/S | 485,438 | $29.3M | 1.71% | 00.0% | Unchanged |
| Octagon Capital Advisors LP | 490,000 | $29.6M | 2.71% | 00.0% | Unchanged |
| Loomis Sayles & Co L P | 527,273 | $31.8M | 0.04% | −37,624−6.7% | Reduced |
| Tudor Investment Corp Et Al | 545,387 | $32.9M | 0.14% | +49,796+10.0% | Added |
| First Turn Management, LLC | 600,200 | $36.2M | 3.88% | −186,644−23.7% | Reduced |
| Panagora Asset Management Inc | 664,031 | $40.1M | 0.12% | +664,031 | New |
| Northern Trust Corp | 671,566 | $40.5M | 0.00% | +143,783+27.2% | Added |
| Rock Springs Capital Management LP | 683,907 | $41.3M | 2.01% | −79,113−10.4% | Reduced |
| Marshall Wace, LLP | 689,342 | $41.6M | 0.04% | +689,342 | New |
| Alyeska Investment Group, L.P. | 697,692 | $42.1M | 0.11% | −601,777−46.3% | Reduced |
| Vestal Point Capital, LP | 700,000 | $42.3M | 0.99% | +60,100+9.4% | Added |
| Vanguard Portfolio Management LLC | 749,651 | $45.2M | 0.00% | +206,589+38.0% | Added |
| Goldman Sachs Group Inc | 773,625 | $46.7M | 0.00% | +3,750+0.5% | Added |
| Capital World Investors | 862,775 | $52.1M | 0.01% | +22,703+2.7% | Added |
| Federated Hermes, Inc. | 883,737 | $53.3M | 0.08% | −88,500−9.1% | Reduced |
| American Century Companies Inc | 884,319 | $53.4M | 0.02% | +205,005+30.2% | Added |
| Caligan Partners LP | 889,944 | $53.7M | 2.59% | −503,083−36.1% | Reduced |
| OrbiMed Advisors LLC | 892,471 | $53.9M | 1.02% | −167,500−15.8% | Reduced |
| Invesco Ltd. | 903,458 | $54.5M | 0.00% | +844,355+1,428.6% | Added |
| Nuveen, LLC | 993,126 | $59.9M | 0.01% | +743,090+297.2% | Added |
| Braidwell LP | 1,131,452 | $68.3M | 2.53% | −207,000−15.5% | Reduced |
| Pictet Asset Management Holding SA | 1,187,723 | $71.6M | 0.07% | +508,014+74.7% | Added |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 1,290,731 | $77.9M | 0.08% | −51,297−3.8% | Reduced |
| Siren, L.L.C. | 1,318,564 | $79.6M | 1.62% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 1,370,114 | $82.7M | 0.00% | +277,182+25.4% | Added |
| Citadel Advisors LLC | 1,401,242 | $84.6M | 0.05% | −1,251,748−47.2% | Reduced |
| Wellington Management Group LLP | 1,425,492 | $86.0M | 0.01% | −3,404,149−70.5% | Reduced |
| Franklin Resources Inc | 1,437,712 | $86.8M | 0.02% | +157,135+12.3% | Added |
| Alliancebernstein L.P. | 1,562,276 | $90.8M | 0.03% | +158,979+11.3% | Added |