Skip to main content

Xenon Pharmaceuticals Inc.

XENE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001582313

In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.

13F holders, Q2 2026

Institutional positions in Xenon Pharmaceuticals Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
315
+27 vs. Q1 2026
Shares held
101.1M
+5.07M (+5.3%) vs. Q1 2026
Total value
$6.10B
+$538.5M (+9.7%) vs. Q1 2026
New holders
49
126 more added
Sold out
22
87 more reduced

2 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 315 institutions
Q1 2021: 91 institutionsQ2 2021: 103 institutionsQ3 2021: 118 institutionsQ4 2021: 130 institutionsQ1 2022: 132 institutionsQ2 2022: 151 institutionsQ3 2022: 154 institutionsQ4 2022: 159 institutionsQ1 2023: 163 institutionsQ2 2023: 175 institutionsQ3 2023: 181 institutionsQ4 2023: 204 institutionsQ1 2024: 220 institutionsQ2 2024: 213 institutionsQ3 2024: 203 institutionsQ4 2024: 209 institutionsQ1 2025: 206 institutionsQ2 2025: 206 institutionsQ3 2025: 219 institutionsQ4 2025: 245 institutionsQ1 2026: 290 institutionsQ2 2026: 315 institutions
Value heldQ2 2026: $6.10B
Q1 2021: $590.0MQ2 2021: $620.0MQ3 2021: $521.7MQ4 2021: $1.49BQ1 2022: $1.50BQ2 2022: $1.73BQ3 2022: $2.09BQ4 2022: $2.38BQ1 2023: $2.19BQ2 2023: $2.36BQ3 2023: $2.10BQ4 2023: $3.32BQ1 2024: $3.16BQ2 2024: $2.89BQ3 2024: $2.95BQ4 2024: $2.99BQ1 2025: $2.58BQ2 2025: $2.60BQ3 2025: $3.39BQ4 2025: $3.78BQ1 2026: $5.80BQ2 2026: $6.10B
Institutions holding XENE and their total value by quarter
QuarterHoldersValue
Q2 2026315$6.10B
Q1 2026290$5.80B
Q4 2025245$3.78B
Q3 2025219$3.39B
Q2 2025206$2.60B
Q1 2025206$2.58B
Q4 2024209$2.99B
Q3 2024203$2.95B
Q2 2024213$2.89B
Q1 2024220$3.16B
Q4 2023204$3.32B
Q3 2023181$2.10B
Q2 2023175$2.36B
Q1 2023163$2.19B
Q4 2022159$2.38B
Q3 2022154$2.09B
Q2 2022151$1.73B
Q1 2022132$1.50B
Q4 2021130$1.49B
Q3 2021118$521.7M
Q2 2021103$620.0M
Q1 202191$590.0M

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q1 2026.

Institutions holding XENE in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Blackstone Group Inc.7,608$459.2K0.00%+7,608New
Himension Fund7,666$462.7K0.03%+7,666New
Great West Life Assurance Co8,061$485.0K0.00%+1,037+14.8%Added
Allstate Corp8,180$493.7K0.00%+8,180New
Bridgefront Capital, LLC8,239$497.3K0.13%+1,675+25.5%Added
Toroso Investments, LLC8,283$500.0K0.00%+2,058+33.1%Added
The PNC Financial Services Group, Inc.8,701$525.2K0.00%+604+7.5%Added
State of Wyoming8,710$525.7K0.05%+7,329+530.7%Added
JustInvest LLC8,745$527.8K0.00%−16−0.2%Reduced
Hudson Bay Capital Management LP8,772$529.5K0.00%−5,300−37.7%Reduced
First Trust Advisors LP8,811$531.8K0.00%−322−3.5%Reduced
Ameritas Investment Partners, Inc.8,909$537.7K0.01%+1,771+24.8%Added
Capstone Investment Advisors, LLC8,925$538.7K0.00%+8,925New
Thrivent Financial for Lutherans9,122$551.0K0.00%00.0%Unchanged
TD Asset Management Inc9,400$567.4K0.00%−17,674−65.3%Reduced
Teacher Retirement System of Texas9,482$572.3K0.00%+1,883+24.8%Added
Xponance, Inc.9,660$583.1K0.00%+1,195+14.1%Added
Elmwood Wealth Management, Inc.9,817$592.6K0.15%+10+0.1%Added
Brevan Howard Capital Management LP9,945$600.3K0.01%−2,096−17.4%Reduced
Public Employees Retirement Association of Colorado10,633$642.0K0.00%00.0%Unchanged
Allianz Asset Management GmbH10,700$645.9K0.00%+3,100+40.8%Added
Amundi10,719$647.0K0.00%−7,294−40.5%Reduced
EntryPoint Capital, LLC13,177$795.4K0.19%+4,345+49.2%Added
STRS Ohio13,800$833.0K0.00%+8,100+142.1%Added
Fieldview Capital Management, LLC13,930$840.8K0.24%+13,930New
Brinker Capital Investments, LLC14,114$851.9K0.01%+297+2.1%Added
SBI Okasan Asset Management Co.Ltd.14,400$865.9K0.03%00.0%Unchanged
IMC-Chicago, LLC15,083$910.4K0.01%+15,083New
Campbell & CO Investment Adviser LLC15,134$913.5K0.05%−3,022−16.6%Reduced
China Universal Asset Management Co., Ltd.15,384$928.6K0.06%+621+4.2%Added
ProShare Advisors LLC16,020$967.0K0.00%−230−1.4%Reduced
Stifel Financial Corp16,442$992.4K0.00%−276−1.7%Reduced
J. Safra Sarasin Holding AG17,750$1.07M0.02%+8,679+95.7%Added
Magnetar Financial LLC18,213$1.10M0.01%+18,213New
KLP Kapitalforvaltning AS18,400$1.11M0.00%+800+4.5%Added
Martingale Asset Management L P18,410$1.11M0.03%−396−2.1%Reduced
XTX Topco Ltd19,297$1.16M0.02%−8,703−31.1%Reduced
Assetmark, Inc19,334$1.17M0.00%−938−4.6%Reduced
Vanguard Investments Australia, Ltd.19,954$1.20M0.00%00.0%Unchanged
CIBC World Markets Inc.19,960$1.20M0.00%+1,000+5.3%Added
Barclays PLC20,046$1.21M0.00%−218,163−91.6%Reduced
Capricorn Fund Managers Ltd20,900$1.26M0.10%+20,900New
Birchview Capital, LP21,032$1.27M0.59%+32+0.2%Added
Teachers Retirement System of the State of Kentucky21,133$1.28M0.01%00.0%Unchanged
Intech Investment Management LLC21,758$1.31M0.01%+2,696+14.1%Added
Dark Forest Capital Management LP22,234$1.34M0.09%+22,234New
Susquehanna International Group, LLP22,258$1.34M0.00%−154,879−87.4%Reduced
State Board of Administration of Florida Retirement System22,365$1.35M0.00%+3,268+17.1%Added
Arizona State Retirement System22,382$1.35M0.01%+513+2.3%Added
HighMark Wealth Management LLC23,000$1.39M0.47%00.0%Unchanged
Rathbone Brothers plc23,166$1.40M0.01%−500−2.1%Reduced
Vestmark Advisory Solutions, Inc.24,025$1.45M0.01%00.0%Unchanged
Creative Planning24,805$1.50M0.00%−5,013−16.8%Reduced
Bamco Inc25,000$1.51M0.00%00.0%Unchanged
State of New Jersey Common Pension Fund D26,227$1.58M0.01%+6,420+32.4%Added
UBS Group AG28,251$1.71M0.00%−71,373−71.6%Reduced
CI Private Wealth, LLC28,732$1.73M0.00%+430+1.5%Added
Manufacturers Life Insurance Company, The28,932$1.75M0.00%+7,248+33.4%Added
Police & Firemen's Retirement System of New Jersey28,954$1.75M0.01%+5,549+23.7%Added
Headlands Technologies LLC29,194$1.76M0.19%+23,074+377.0%Added
Handelsbanken Fonder AB29,800$1.80M0.01%00.0%Unchanged
Connor, Clark & Lunn Investment Management Ltd.30,354$1.83M0.00%+10,915+56.2%Added
TLS Advisors LLC30,956$1.87M5.49%00.0%Unchanged
BNP Paribas Arbitrage, SA31,791$1.92M0.00%−48,601−60.5%Reduced
Rhenman & Partners Asset Management AB33,250$2.01M0.19%+5,250+18.8%Added
Seven Fleet Capital Management LP33,300$2.08M0.34%+33,300New
HighVista Strategies LLC35,318$2.13M0.49%−13,732−28.0%Reduced
DekaBank Deutsche Girozentrale39,000$2.16M0.00%00.0%Unchanged
Envestnet Asset Management Inc36,005$2.17M0.00%−63−0.2%Reduced
Dimensional Fund Advisors LP36,595$2.21M0.00%+36,595New
Aquatic Capital Management LLC38,293$2.31M0.08%−40,906−51.6%Reduced
Oak Ridge Investments LLC38,559$2.33M0.13%+38,559New
Diversified Trust Co39,222$2.37M0.04%+39,222New
Prudential Financial Inc39,400$2.38M0.00%+26,390+202.8%Added
Verition Fund Management LLC40,000$2.41M0.02%−15,000−27.3%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)44,096$2.66M0.01%+8,892+25.3%Added
Lazard Asset Management LLC44,125$2.66M0.00%−6,630−13.1%Reduced
Mirae Asset Global ETFs Holdings Ltd.45,014$2.72M0.00%+4,501+11.1%Added
ACT Capital Management, LLC48,000$2.90M1.89%+14,500+43.3%Added
EAM Investors, LLC48,163$2.91M0.26%−18,387−27.6%Reduced
Erste Asset Management GmbH50,000$3.01M0.02%00.0%Unchanged
Palo Alto Investors LP51,345$3.10M0.43%00.0%Unchanged
Legato Capital Management LLC54,226$3.27M0.27%+17,585+48.0%Added
Nomura Asset Management International Inc.54,656$3.30M0.00%+7,615+16.2%Added
MetLife Investment Management57,221$3.45M0.02%+9,878+20.9%Added
Castleark Management LLC61,763$3.73M0.10%−2,800−4.3%Reduced
Engineers Gate Manager LP62,183$3.75M0.05%+52,857+566.8%Added
Quantinno Capital Management LP63,652$3.84M0.00%+8,208+14.8%Added
Victory Capital Management Inc64,225$3.88M0.00%+14,255+28.5%Added
Artia Global Partners LP65,000$3.92M0.75%00.0%Unchanged
Royce & Associates LP65,032$3.93M0.03%+65,032New
Legal & General Group Plc73,728$4.45M0.00%+239+0.3%Added
Seven Grand Managers, LLC75,000$4.53M0.18%00.0%Unchanged
StemPoint Capital LP76,075$4.59M0.79%−64,680−46.0%Reduced
Swedbank AB76,300$4.61M0.00%+50,100+191.2%Added
Walleye Capital LLC76,955$4.65M0.02%+76,955New
Voya Investment Management LLC77,245$4.66M0.00%+8,882+13.0%Added
Vanguard Capital Management LLC77,770$4.69M0.00%+11,809+17.9%Added
Vanguard Asset Management, Ltd82,100$4.96M0.00%+7,619+10.2%Added
Capital Fund Management S.A.84,470$5.10M0.04%+84,470New