Xenon Pharmaceuticals Inc.
XENE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001582313
In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q1 2026
Institutional positions in Xenon Pharmaceuticals Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 290
- +49 vs. Q4 2025
- Shares held
- 100.2M
- +16.7M (+20.0%) vs. Q4 2025
- Total value
- $5.80B
- +$2.06B (+55.0%) vs. Q4 2025
- New holders
- 82
- 123 more added
- Sold out
- 33
- 60 more reduced
4 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 315 | $6.10B |
| Q1 2026 | 290 | $5.80B |
| Q4 2025 | 245 | $3.78B |
| Q3 2025 | 219 | $3.39B |
| Q2 2025 | 206 | $2.60B |
| Q1 2025 | 206 | $2.58B |
| Q4 2024 | 209 | $2.99B |
| Q3 2024 | 203 | $2.95B |
| Q2 2024 | 213 | $2.89B |
| Q1 2024 | 220 | $3.16B |
| Q4 2023 | 204 | $3.32B |
| Q3 2023 | 181 | $2.10B |
| Q2 2023 | 175 | $2.36B |
| Q1 2023 | 163 | $2.19B |
| Q4 2022 | 159 | $2.38B |
| Q3 2022 | 154 | $2.09B |
| Q2 2022 | 151 | $1.73B |
| Q1 2022 | 132 | $1.50B |
| Q4 2021 | 130 | $1.49B |
| Q3 2021 | 118 | $521.7M |
| Q2 2021 | 103 | $620.0M |
| Q1 2021 | 91 | $590.0M |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Engineers Gate Manager LP | 9,326 | $542.3K | 0.01% | +9,326 | New |
| Elmwood Wealth Management, Inc. | 9,807 | $570.3K | 0.16% | −950−8.8% | Reduced |
| Covalis Capital LLP | 10,000 | $581.5K | 0.04% | +10,000 | New |
| Public Employees Retirement Association of Colorado | 10,633 | $618.0K | 0.00% | 00.0% | Unchanged |
| Brevan Howard Capital Management LP | 12,041 | $700.2K | 0.01% | +12,041 | New |
| Citigroup Inc | 12,151 | $706.6K | 0.00% | +4,790+65.1% | Added |
| Prudential Financial Inc | 13,010 | $756.5K | 0.00% | +13,010 | New |
| Neo Ivy Capital Management | 13,710 | $797.2K | 0.21% | +6,233+83.4% | Added |
| SBI Okasan Asset Management Co.Ltd. | 14,400 | $799.9K | 0.03% | 00.0% | Unchanged |
| Brinker Capital Investments, LLC | 13,817 | $803.4K | 0.01% | −590−4.1% | Reduced |
| Hudson Bay Capital Management LP | 14,072 | $818.3K | 0.00% | +14,072 | New |
| China Universal Asset Management Co., Ltd. | 14,763 | $858.5K | 0.06% | +2,171+17.2% | Added |
| ProShare Advisors LLC | 16,250 | $944.9K | 0.00% | −1,029−6.0% | Reduced |
| Stifel Financial Corp | 16,718 | $972.2K | 0.00% | −830−4.7% | Reduced |
| KLP Kapitalforvaltning AS | 17,600 | $1.02M | 0.00% | +5,300+43.1% | Added |
| Amundi | 18,013 | $1.05M | 0.00% | +13,404+290.8% | Added |
| Campbell & CO Investment Adviser LLC | 18,156 | $1.06M | 0.06% | +2,051+12.7% | Added |
| Susquehanna Portfolio Strategies, LLC | 18,468 | $1.07M | 0.02% | +18,468 | New |
| Martingale Asset Management L P | 18,806 | $1.09M | 0.03% | +18,806 | New |
| D. E. Shaw & Co., Inc. | 18,940 | $1.10M | 0.00% | −11,911−38.6% | Reduced |
| CIBC World Markets Inc. | 18,960 | $1.10M | 0.00% | +5,500+40.9% | Added |
| Intech Investment Management LLC | 19,062 | $1.11M | 0.01% | −6,778−26.2% | Reduced |
| State Board of Administration of Florida Retirement System | 19,097 | $1.11M | 0.00% | +19,097 | New |
| Connor, Clark & Lunn Investment Management Ltd. | 19,439 | $1.13M | 0.00% | +19,439 | New |
| State of New Jersey Common Pension Fund D | 19,807 | $1.15M | 0.00% | +69+0.3% | Added |
| Vanguard Investments Australia, Ltd. | 19,954 | $1.16M | 0.00% | +19,954 | New |
| Assetmark, Inc | 20,272 | $1.18M | 0.00% | −997−4.7% | Reduced |
| Birchview Capital, LP | 21,000 | $1.22M | 0.70% | 00.0% | Unchanged |
| Teachers Retirement System of the State of Kentucky | 21,133 | $1.23M | 0.01% | +21,133 | New |
| Sanders Morris Harris LLC | 21,500 | $1.25M | 0.20% | +21,500 | New |
| Manufacturers Life Insurance Company, The | 21,684 | $1.26M | 0.00% | −10,938−33.5% | Reduced |
| Arizona State Retirement System | 21,869 | $1.27M | 0.01% | +5,690+35.2% | Added |
| HighMark Wealth Management LLC | 23,000 | $1.34M | 0.54% | 00.0% | Unchanged |
| Police & Firemen's Retirement System of New Jersey | 23,405 | $1.36M | 0.01% | +3,277+16.3% | Added |
| Rathbone Brothers plc | 23,666 | $1.38M | 0.01% | 00.0% | Unchanged |
| Vestmark Advisory Solutions, Inc. | 24,025 | $1.40M | 0.02% | +2,141+9.8% | Added |
| Bamco Inc | 25,000 | $1.45M | 0.00% | −5,000−16.7% | Reduced |
| SummitTX Capital, L.P. | 26,186 | $1.52M | 0.05% | +26,186 | New |
| Swedbank AB | 26,200 | $1.52M | 0.00% | +26,200 | New |
| TD Asset Management Inc | 27,074 | $1.57M | 0.00% | −11,074−29.0% | Reduced |
| Rhenman & Partners Asset Management AB | 28,000 | $1.63M | 0.20% | −111,000−79.9% | Reduced |
| XTX Topco Ltd | 28,000 | $1.63M | 0.03% | +6,502+30.2% | Added |
| CI Private Wealth, LLC | 28,302 | $1.65M | 0.00% | +28,302 | New |
| Handelsbanken Fonder AB | 29,800 | $1.73M | 0.01% | 00.0% | Unchanged |
| Creative Planning | 29,818 | $1.73M | 0.00% | +10,618+55.3% | Added |
| Calamos Advisors LLC | 30,374 | $1.77M | 0.01% | +30,374 | New |
| TLS Advisors LLC | 30,956 | $1.80M | 4.27% | +12,098+64.2% | Added |
| ACT Capital Management, LLC | 33,500 | $1.95M | 1.53% | +33,500 | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 35,204 | $2.05M | 0.00% | +9,615+37.6% | Added |
| Envestnet Asset Management Inc | 36,068 | $2.10M | 0.00% | +267+0.7% | Added |
| Legato Capital Management LLC | 36,641 | $2.13M | 0.19% | −397−1.1% | Reduced |
| DekaBank Deutsche Girozentrale | 39,000 | $2.20M | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global ETFs Holdings Ltd. | 40,513 | $2.36M | 0.00% | +5,203+14.7% | Added |
| Qube Research & Technologies Ltd | 44,044 | $2.56M | 0.00% | +44,044 | New |
| Nomura Asset Management International Inc. | 47,041 | $2.73M | 0.00% | −916−1.9% | Reduced |
| MetLife Investment Management | 47,343 | $2.75M | 0.01% | +5,318+12.7% | Added |
| Erste Asset Management GmbH | 50,000 | $2.78M | 0.03% | 00.0% | Unchanged |
| HighVista Strategies LLC | 49,050 | $2.85M | 0.79% | +49,050 | New |
| Victory Capital Management Inc | 49,970 | $2.91M | 0.00% | +49,970 | New |
| Lazard Asset Management LLC | 50,755 | $2.95M | 0.00% | −27,908−35.5% | Reduced |
| Palo Alto Investors LP | 51,345 | $2.99M | 0.46% | −45,174−46.8% | Reduced |
| Verition Fund Management LLC | 55,000 | $3.20M | 0.03% | −38,756−41.3% | Reduced |
| Quantinno Capital Management LP | 55,444 | $3.22M | 0.01% | +30,816+125.1% | Added |
| LMR Partners LLP | 56,200 | $3.27M | 0.03% | +56,200 | New |
| Invesco Ltd. | 59,103 | $3.44M | 0.00% | +8,156+16.0% | Added |
| Atika Capital Management LLC | 59,900 | $3.48M | 0.55% | −32,606−35.2% | Reduced |
| Castleark Management LLC | 64,563 | $3.75M | 0.12% | +64,563 | New |
| Artia Global Partners LP | 65,000 | $3.78M | 0.85% | +25,000+62.5% | Added |
| Vanguard Capital Management LLC | 65,961 | $3.84M | 0.00% | +65,961 | New |
| EAM Investors, LLC | 66,550 | $3.87M | 0.45% | +66,550 | New |
| Trexquant Investment LP | 67,361 | $3.92M | 0.03% | +67,361 | New |
| Alps Advisors Inc | 67,723 | $3.94M | 0.02% | +4,421+7.0% | Added |
| Voya Investment Management LLC | 68,363 | $3.98M | 0.00% | +7,505+12.3% | Added |
| Legal & General Group Plc | 73,489 | $4.27M | 0.00% | +3,224+4.6% | Added |
| Vanguard Asset Management, Ltd | 74,481 | $4.33M | 0.00% | +74,481 | New |
| Seven Grand Managers, LLC | 75,000 | $4.36M | 0.29% | +75,000 | New |
| Vanguard Fiduciary Trust Co | 75,117 | $4.37M | 0.00% | +75,117 | New |
| Schroder Investment Management Group | 81,156 | $4.51M | 0.00% | 00.0% | Unchanged |
| Ameriprise Financial Inc | 78,905 | $4.59M | 0.00% | −30,639−28.0% | Reduced |
| Aquatic Capital Management LLC | 79,199 | $4.61M | 0.13% | +79,199 | New |
| BNP Paribas Arbitrage, SA | 80,392 | $4.67M | 0.00% | −13,070−14.0% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 85,388 | $4.97M | 0.09% | +12,431+17.0% | Added |
| Raymond James Financial Inc | 88,598 | $5.15M | 0.00% | +5,343+6.4% | Added |
| Royal Bank of Canada | 90,387 | $5.25M | 0.00% | +630+0.7% | Added |
| California State Teachers Retirement System | 92,747 | $5.39M | 0.01% | +36,183+64.0% | Added |
| Axiom Investors LLC | 99,568 | $5.79M | 0.06% | +99,568 | New |
| UBS Group AG | 99,624 | $5.79M | 0.00% | +47,085+89.6% | Added |
| Burkehill Global Management, LP | 100,000 | $5.82M | 0.29% | +100,000 | New |
| Rhumbline Advisers | 101,785 | $5.92M | 0.01% | +11,642+12.9% | Added |
| Granahan Investment Management Inc | 104,478 | $6.08M | 0.29% | +11,700+12.6% | Added |
| SEI Investments Co | 114,381 | $6.65M | 0.01% | +70,523+160.8% | Added |
| Mutual of America Capital Management LLC | 115,594 | $6.72M | 0.08% | −494−0.4% | Reduced |
| Wells Fargo & Company | 115,652 | $6.73M | 0.00% | −36,645−24.1% | Reduced |
| HSBC Holdings PLC | 121,558 | $7.07M | 0.00% | +121,558 | New |
| Sphera Funds Management Ltd. | 127,000 | $7.39M | 1.27% | +127,000 | New |
| KBC Group NV | 129,010 | $7.50M | 0.02% | +126,230+4,540.6% | Added |
| Russell Investments Group, Ltd. | 129,399 | $7.52M | 0.01% | +43,179+50.1% | Added |
| Eversept Partners, LP | 129,574 | $7.53M | 0.50% | −101,806−44.0% | Reduced |
| Neuberger Berman Group LLC | 130,438 | $7.58M | 0.01% | −48,309−27.0% | Reduced |
| StemPoint Capital LP | 140,755 | $8.18M | 1.57% | −207,850−59.6% | Reduced |