Xenon Pharmaceuticals Inc.
XENE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001582313
In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q4 2025
Institutional positions in Xenon Pharmaceuticals Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 245
- +28 vs. Q3 2025
- Shares held
- 84.4M
- +294.5K (+0.4%) vs. Q3 2025
- Total value
- $3.78B
- +$405.9M (+12.0%) vs. Q3 2025
- New holders
- 50
- 81 more added
- Sold out
- 22
- 74 more reduced
2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 315 | $6.10B |
| Q1 2026 | 290 | $5.80B |
| Q4 2025 | 245 | $3.78B |
| Q3 2025 | 219 | $3.39B |
| Q2 2025 | 206 | $2.60B |
| Q1 2025 | 206 | $2.58B |
| Q4 2024 | 209 | $2.99B |
| Q3 2024 | 203 | $2.95B |
| Q2 2024 | 213 | $2.89B |
| Q1 2024 | 220 | $3.16B |
| Q4 2023 | 204 | $3.32B |
| Q3 2023 | 181 | $2.10B |
| Q2 2023 | 175 | $2.36B |
| Q1 2023 | 163 | $2.19B |
| Q4 2022 | 159 | $2.38B |
| Q3 2022 | 154 | $2.09B |
| Q2 2022 | 151 | $1.73B |
| Q1 2022 | 132 | $1.50B |
| Q4 2021 | 130 | $1.49B |
| Q3 2021 | 118 | $521.7M |
| Q2 2021 | 103 | $620.0M |
| Q1 2021 | 91 | $590.0M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| SBI Securities Co., Ltd. | 1 | $45 | 0.00% | 00.0% | Unchanged |
| Larson Financial Group LLC | 2 | $90 | 0.00% | 00.0% | Unchanged |
| TD Private Client Wealth LLC | 3 | $134 | 0.00% | +3 | New |
| Massmutual Trust Co FSB | 11 | $493 | 0.00% | +11 | New |
| UMA Financial Services, Inc. | 13 | $583 | 0.00% | +13 | New |
| Smartleaf Asset Management LLC | 16 | $706 | 0.00% | +16 | New |
| Park Place Capital Corp | 16 | $717 | 0.00% | 00.0% | Unchanged |
| CoreCap Advisors, LLC | 17 | $762 | 0.00% | +17 | New |
| Hantz Financial Services, Inc. | 25 | $1.00K | 0.00% | +25 | New |
| SRS Capital Advisors, Inc. | 27 | $1.21K | 0.00% | −92−77.3% | Reduced |
| Parkside Financial Bank & Trust | 30 | $1.34K | 0.00% | 00.0% | Unchanged |
| CVA Family Office, LLC | 33 | $1.48K | 0.00% | 00.0% | Unchanged |
| Aster Capital Management (DIFC) Ltd | 36 | $1.61K | 0.00% | −923−96.2% | Reduced |
| Cape Investment Advisory, Inc. | 39 | $1.75K | 0.00% | 00.0% | Unchanged |
| Motiv8 Investments LLC | 40 | $2.00K | 0.00% | +40 | New |
| Rossby Financial, LCC | 47 | $2.11K | 0.00% | +7+17.5% | Added |
| J.Safra Asset Management Corp | 87 | $3.90K | 0.00% | 00.0% | Unchanged |
| Bell Investment Advisors, Inc | 100 | $4.48K | 0.00% | +89+809.1% | Added |
| Rothschild Investment LLC | 111 | $4.97K | 0.00% | −4−3.5% | Reduced |
| Allworth Financial LP | 116 | $5.20K | 0.00% | −10−7.9% | Reduced |
| Kemnay Advisory Services Inc. | 123 | $5.51K | 0.00% | +123 | New |
| Parallel Advisors, LLC | 147 | $6.59K | 0.00% | 00.0% | Unchanged |
| Jones Financial Companies LLLP | 150 | $6.72K | 0.00% | +150 | New |
| US Bancorp | 175 | $7.84K | 0.00% | 00.0% | Unchanged |
| National Bank of Canada | 190 | $8.52K | 0.00% | −10−5.0% | Reduced |
| EverSource Wealth Advisors, LLC | 212 | $9.50K | 0.00% | +172+430.0% | Added |
| Daiwa Securities Group Inc. | 229 | $10.0K | 0.00% | −23−9.1% | Reduced |
| Zions Bancorporation, National Association | 235 | $10.5K | 0.00% | +235 | New |
| UBS Asset Management Americas Inc | 236 | $10.6K | 0.00% | +236 | New |
| Covestor Ltd | 247 | $11.0K | 0.01% | +244+8,133.3% | Added |
| MAI Capital Management | 261 | $11.7K | 0.00% | +261 | New |
| GAMMA Investing LLC | 264 | $11.8K | 0.00% | +79+42.7% | Added |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 276 | $12.3K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 319 | $14.3K | 0.00% | −1,055−76.8% | Reduced |
| CWM, LLC | 366 | $16.0K | 0.00% | +31+9.3% | Added |
| Signaturefd, LLC | 473 | $21.2K | 0.00% | +57+13.7% | Added |
| Sterling Capital Management LLC | 491 | $22.0K | 0.00% | +307+166.8% | Added |
| Kestra Advisory Services, LLC | 740 | $33.2K | 0.00% | +740 | New |
| Ronald Blue Trust, Inc. | 745 | $33.4K | 0.00% | +717+2,560.7% | Added |
| Danske Bank A/S | 800 | $35.9K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 924 | $41.4K | 0.00% | 00.0% | Unchanged |
| Farther Finance Advisors, LLC | 1,058 | $47.4K | 0.00% | +212+25.1% | Added |
| Rockefeller Capital Management L.P. | 1,100 | $49.3K | 0.00% | +900+450.0% | Added |
| Clearstead Advisors, LLC | 1,215 | $54.5K | 0.00% | +829+214.8% | Added |
| Caitong International Asset Management Co., Ltd | 1,225 | $54.9K | 0.01% | +1,225 | New |
| STRS Ohio | 1,300 | $58.3K | 0.00% | +1,300 | New |
| State of Wyoming | 1,501 | $67.3K | 0.01% | +350+30.4% | Added |
| GF Fund Management Co. Ltd. | 1,517 | $68.0K | 0.00% | −142−8.6% | Reduced |
| IFP Advisors, Inc | 1,877 | $84.1K | 0.00% | −31−1.6% | Reduced |
| Amalgamated Bank | 2,387 | $107.0K | 0.00% | −208−8.0% | Reduced |
| KBC Group NV | 2,780 | $125.0K | 0.00% | +909+48.6% | Added |
| Tower Research Capital LLC (TRC) | 3,232 | $144.9K | 0.00% | +1,715+113.1% | Added |
| Mirae Asset Global Investments Co., Ltd. | 3,755 | $168.3K | 0.00% | +774+26.0% | Added |
| Principal Financial Group Inc | 4,488 | $201.2K | 0.00% | −1,330−22.9% | Reduced |
| JustInvest LLC | 4,533 | $203.2K | 0.00% | +4,533 | New |
| Amundi | 4,609 | $206.6K | 0.00% | +4,609 | New |
| Whalen Wealth Management Inc. | 4,641 | $208.0K | 0.11% | +4,641 | New |
| Mackenzie Financial Corp | 4,772 | $210.1K | 0.00% | +4,772 | New |
| Citizens Financial Group Inc | 5,000 | $224.1K | 0.00% | 00.0% | Unchanged |
| Northwestern Mutual Wealth Management Co | 5,000 | $224.1K | 0.00% | 00.0% | Unchanged |
| CIBC World Markets Corp | 5,027 | $225.3K | 0.00% | +5,027 | New |
| EntryPoint Capital, LLC | 5,028 | $225.4K | 0.09% | 00.0% | Unchanged |
| CAPROCK Group, Inc. | 5,069 | $227.2K | 0.00% | +5,069 | New |
| Magnetar Financial LLC | 5,153 | $231.0K | 0.00% | +5,153 | New |
| Ensign Peak Advisors, Inc | 5,194 | $232.8K | 0.00% | −10,050−65.9% | Reduced |
| Thrivent Financial for Lutherans | 5,583 | $250.0K | 0.00% | −10,518−65.3% | Reduced |
| Xponance, Inc. | 5,975 | $267.8K | 0.00% | +8+0.1% | Added |
| Letson Investment Management, Inc. | 6,000 | $268.9K | 0.10% | +6,000 | New |
| Virtus Investment Advisers, Inc. | 6,037 | $270.6K | 0.07% | +2,568+74.0% | Added |
| Ameritas Investment Partners, Inc. | 6,168 | $276.4K | 0.01% | −390−5.9% | Reduced |
| First Trust Advisors LP | 6,361 | $285.1K | 0.00% | +6,361 | New |
| The PNC Financial Services Group, Inc. | 6,574 | $294.6K | 0.00% | +675+11.4% | Added |
| Abel Hall, LLC | 6,757 | $302.8K | 0.07% | +6,757 | New |
| TLS Advisors LLC | 18,858 | $307.0K | 0.81% | −14,098−42.8% | Reduced |
| PenderFund Capital Management Ltd. | 6,850 | $307.0K | 0.05% | 00.0% | Unchanged |
| Great West Life Assurance Co | 7,024 | $315.0K | 0.00% | 00.0% | Unchanged |
| SG Americas Securities, LLC | 7,077 | $317.0K | 0.00% | +149+2.2% | Added |
| Citigroup Inc | 7,361 | $329.9K | 0.00% | −7,509−50.5% | Reduced |
| Oxford Asset Management LLP | 7,379 | $330.7K | 0.12% | −14,783−66.7% | Reduced |
| Neo Ivy Capital Management | 7,477 | $335.1K | 0.05% | −42,361−85.0% | Reduced |
| Advisors Asset Management, Inc. | 8,012 | $359.1K | 0.01% | −3,452−30.1% | Reduced |
| Altfest L J & Co Inc | 8,232 | $369.0K | 0.04% | +501+6.5% | Added |
| Susquehanna International Group, LLP | 8,319 | $372.9K | 0.00% | −37,588−81.9% | Reduced |
| Teacher Retirement System of Texas | 8,632 | $386.9K | 0.00% | −7,369−46.1% | Reduced |
| Allianz Asset Management GmbH | 9,400 | $421.3K | 0.00% | 00.0% | Unchanged |
| Harbor Capital Advisors, Inc. | 10,053 | $451.0K | 0.04% | −1,165−10.4% | Reduced |
| Marex Group plc | 10,557 | $473.2K | 0.01% | +10,557 | New |
| Public Employees Retirement Association of Colorado | 10,633 | $477.0K | 0.00% | 00.0% | Unchanged |
| Elmwood Wealth Management, Inc. | 10,757 | $482.1K | 0.15% | −150−1.4% | Reduced |
| Knott David M Jr | 10,962 | $491.3K | 0.23% | 00.0% | Unchanged |
| Supplemental Annuity Collective Trust of NJ | 11,000 | $493.0K | 0.13% | 00.0% | Unchanged |
| Himension Fund | 11,279 | $505.5K | 0.03% | +11,279 | New |
| PSP Research LLC | 11,678 | $523.4K | 0.46% | +11,678 | New |
| KLP Kapitalforvaltning AS | 12,300 | $551.3K | 0.00% | −500−3.9% | Reduced |
| China Universal Asset Management Co., Ltd. | 12,592 | $564.4K | 0.04% | −923−6.8% | Reduced |
| CIBC World Markets Inc. | 13,460 | $603.3K | 0.00% | 00.0% | Unchanged |
| J. Safra Sarasin Holding AG | 13,581 | $608.7K | 0.01% | −16,587−55.0% | Reduced |
| SBI Okasan Asset Management Co.Ltd. | 14,400 | $638.4K | 0.04% | +14,400 | New |
| Brinker Capital Investments, LLC | 14,407 | $645.7K | 0.00% | −511−3.4% | Reduced |
| Campbell & CO Investment Adviser LLC | 16,105 | $721.8K | 0.03% | −12,564−43.8% | Reduced |