Xenon Pharmaceuticals Inc.
XENE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001582313
In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q3 2025
Institutional positions in Xenon Pharmaceuticals Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 219
- +15 vs. Q2 2025
- Shares held
- 84.3M
- +1.20M (+1.4%) vs. Q2 2025
- Total value
- $3.39B
- +$783.3M (+30.1%) vs. Q2 2025
- New holders
- 35
- 68 more added
- Sold out
- 20
- 71 more reduced
2 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 315 | $6.10B |
| Q1 2026 | 290 | $5.80B |
| Q4 2025 | 245 | $3.78B |
| Q3 2025 | 219 | $3.39B |
| Q2 2025 | 206 | $2.60B |
| Q1 2025 | 206 | $2.58B |
| Q4 2024 | 209 | $2.99B |
| Q3 2024 | 203 | $2.95B |
| Q2 2024 | 213 | $2.89B |
| Q1 2024 | 220 | $3.16B |
| Q4 2023 | 204 | $3.32B |
| Q3 2023 | 181 | $2.10B |
| Q2 2023 | 175 | $2.36B |
| Q1 2023 | 163 | $2.19B |
| Q4 2022 | 159 | $2.38B |
| Q3 2022 | 154 | $2.09B |
| Q2 2022 | 151 | $1.73B |
| Q1 2022 | 132 | $1.50B |
| Q4 2021 | 130 | $1.49B |
| Q3 2021 | 118 | $521.7M |
| Q2 2021 | 103 | $620.0M |
| Q1 2021 | 91 | $590.0M |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| D. E. Shaw & Co., Inc. | 48,455 | $1.95M | 0.00% | −93,328−65.8% | Reduced |
| Susquehanna International Group, LLP | 45,907 | $1.84M | 0.00% | −176,445−79.4% | Reduced |
| MetLife Investment Management | 44,221 | $1.78M | 0.01% | −1,326−2.9% | Reduced |
| Price T Rowe Associates Inc | 41,692 | $1.68M | 0.00% | +3,757+9.9% | Added |
| Artia Global Partners LP | 40,000 | $1.61M | 0.28% | 00.0% | Unchanged |
| Atika Capital Management LLC | 38,000 | $1.53M | 0.13% | +38,000 | New |
| DekaBank Deutsche Girozentrale | 39,000 | $1.51M | 0.00% | 00.0% | Unchanged |
| Envestnet Asset Management Inc | 37,448 | $1.50M | 0.00% | −1,955−5.0% | Reduced |
| Alps Advisors Inc | 37,300 | $1.50M | 0.01% | −4,080−9.9% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 35,301 | $1.42M | 0.00% | −6,347−15.2% | Reduced |
| TLS Advisors LLC | 32,956 | $1.38M | 4.02% | 00.0% | Unchanged |
| J. Safra Sarasin Holding AG | 30,168 | $1.21M | 0.02% | −51,880−63.2% | Reduced |
| Bamco Inc | 30,000 | $1.20M | 0.00% | −26,000−46.4% | Reduced |
| Boothbay Fund Management, LLC | 28,859 | $1.16M | 0.03% | +28,859 | New |
| Campbell & CO Investment Adviser LLC | 28,669 | $1.15M | 0.09% | +28,669 | New |
| HighMark Wealth Management LLC | 26,100 | $1.05M | 0.46% | 00.0% | Unchanged |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 25,589 | $1.03M | 0.00% | +1,723+7.2% | Added |
| NJ State Employees Deferred Compensation Plan | 25,000 | $1.00M | 0.11% | 00.0% | Unchanged |
| Manufacturers Life Insurance Company, The | 23,932 | $960.9K | 0.00% | −2,147−8.2% | Reduced |
| Rathbone Brothers plc | 23,666 | $950.2K | 0.00% | 00.0% | Unchanged |
| Man Group plc | 23,119 | $928.2K | 0.00% | −39,229−62.9% | Reduced |
| Intech Investment Management LLC | 23,086 | $926.9K | 0.01% | −11,226−32.7% | Reduced |
| Cinctive Capital Management LP | 23,054 | $925.6K | 0.05% | +23,054 | New |
| Handelsbanken Fonder AB | 22,700 | $911.0K | 0.00% | 00.0% | Unchanged |
| Assetmark, Inc | 22,566 | $906.0K | 0.00% | +1,316+6.2% | Added |
| SEI Investments Co | 22,423 | $900.3K | 0.00% | −300−1.3% | Reduced |
| Oxford Asset Management LLP | 22,162 | $889.8K | 0.29% | +1,024+4.8% | Added |
| Sanders Morris Harris LLC | 21,500 | $863.2K | 0.11% | +21,500 | New |
| Police & Firemen's Retirement System of New Jersey | 21,032 | $844.4K | 0.01% | +3,674+21.2% | Added |
| Birchview Capital, LP | 21,000 | $843.1K | 0.64% | 00.0% | Unchanged |
| Arizona State Retirement System | 19,290 | $774.5K | 0.00% | +334+1.8% | Added |
| Stifel Financial Corp | 18,715 | $751.4K | 0.00% | −1,907−9.2% | Reduced |
| Two Sigma Advisers, LP | 18,100 | $726.7K | 0.00% | −77,200−81.0% | Reduced |
| Natixis Advisors, L.P. | 17,564 | $705.0K | 0.00% | +140+0.8% | Added |
| TD Asset Management Inc | 16,230 | $651.6K | 0.00% | +16,230 | New |
| Thrivent Financial for Lutherans | 16,101 | $647.0K | 0.00% | +16,101 | New |
| Teacher Retirement System of Texas | 16,001 | $642.4K | 0.00% | −1,533−8.7% | Reduced |
| ProShare Advisors LLC | 15,740 | $632.0K | 0.00% | −2,708−14.7% | Reduced |
| Ensign Peak Advisors, Inc | 15,244 | $612.0K | 0.00% | −10,850−41.6% | Reduced |
| Brinker Capital Investments, LLC | 14,918 | $598.9K | 0.00% | +20.0% | Added |
| Citigroup Inc | 14,870 | $597.0K | 0.00% | −21,420−59.0% | Reduced |
| CenterBook Partners LP | 14,770 | $593.0K | 0.03% | −9,894−40.1% | Reduced |
| Legato Capital Management LLC | 14,209 | $570.5K | 0.06% | +4,587+47.7% | Added |
| China Universal Asset Management Co., Ltd. | 13,515 | $542.6K | 0.04% | −1,897−12.3% | Reduced |
| CIBC World Markets Inc. | 13,460 | $540.4K | 0.00% | −2,875−17.6% | Reduced |
| Quantinno Capital Management LP | 13,371 | $536.8K | 0.00% | +13,371 | New |
| Creative Planning | 13,210 | $530.4K | 0.00% | +13,210 | New |
| KLP Kapitalforvaltning AS | 12,800 | $513.9K | 0.00% | 00.0% | Unchanged |
| Schonfeld Strategic Advisors LLC | 12,652 | $508.0K | 0.00% | +2,114+20.1% | Added |
| Advisors Asset Management, Inc. | 11,464 | $460.3K | 0.01% | −741−6.1% | Reduced |
| Harbor Capital Advisors, Inc. | 11,218 | $450.0K | 0.03% | −18,818−62.7% | Reduced |
| Supplemental Annuity Collective Trust of NJ | 11,000 | $441.6K | 0.12% | 00.0% | Unchanged |
| Knott David M Jr | 10,962 | $440.1K | 0.18% | 00.0% | Unchanged |
| Elmwood Wealth Management, Inc. | 10,907 | $437.9K | 0.16% | +83+0.8% | Added |
| Public Employees Retirement Association of Colorado | 10,633 | $427.0K | 0.00% | 00.0% | Unchanged |
| Allianz Asset Management GmbH | 9,400 | $377.4K | 0.00% | 00.0% | Unchanged |
| DRW Securities, LLC | 9,273 | $373.6K | 0.02% | +9,273 | New |
| Prudential Financial Inc | 8,850 | $355.3K | 0.00% | −38,905−81.5% | Reduced |
| CIBC Bancorp USA Inc. | 8,100 | $325.2K | 0.00% | +8,100 | New |
| Altfest L J & Co Inc | 7,731 | $310.4K | 0.03% | +7,731 | New |
| SG Americas Securities, LLC | 6,928 | $278.0K | 0.00% | −12,249−63.9% | Reduced |
| PenderFund Capital Management Ltd. | 6,850 | $275.0K | 0.05% | +6,850 | New |
| Great West Life Assurance Co | 7,024 | $274.0K | 0.00% | 00.0% | Unchanged |
| Freestone Grove Partners LP | 6,748 | $270.9K | 0.00% | +6,748 | New |
| Ameritas Investment Partners, Inc. | 6,558 | $263.3K | 0.01% | −1,200−15.5% | Reduced |
| Jump Financial, LLC | 6,500 | $261.0K | 0.00% | −10,491−61.7% | Reduced |
| Inceptionr LLC | 6,322 | $253.8K | 0.06% | +6,322 | New |
| Xponance, Inc. | 5,967 | $239.6K | 0.00% | +5,967 | New |
| The PNC Financial Services Group, Inc. | 5,899 | $236.8K | 0.00% | +2,437+70.4% | Added |
| Principal Financial Group Inc | 5,818 | $233.6K | 0.00% | +5,818 | New |
| Renaissance Technologies LLC | 5,200 | $208.8K | 0.00% | −3,400−39.5% | Reduced |
| EntryPoint Capital, LLC | 5,028 | $201.9K | 0.08% | +5,028 | New |
| Northwestern Mutual Wealth Management Co | 5,000 | $200.8K | 0.00% | 00.0% | Unchanged |
| Citizens Financial Group Inc | 5,000 | $200.8K | 0.00% | +5,000 | New |
| Group One Trading, L.P. | 3,556 | $142.8K | 0.00% | −1,097−23.6% | Reduced |
| Virtus Investment Advisers, Inc. | 3,469 | $139.3K | 0.04% | +602+21.0% | Added |
| Mirae Asset Global Investments Co., Ltd. | 2,981 | $119.7K | 0.00% | +17+0.6% | Added |
| Amalgamated Bank | 2,595 | $104.0K | 0.00% | 00.0% | Unchanged |
| Quarry LP | 2,500 | $100.4K | 0.02% | +500+25.0% | Added |
| IFP Advisors, Inc | 1,908 | $76.6K | 0.00% | +43+2.3% | Added |
| KBC Group NV | 1,871 | $75.0K | 0.00% | 00.0% | Unchanged |
| GF Fund Management Co. Ltd. | 1,659 | $66.6K | 0.00% | −293−15.0% | Reduced |
| Tower Research Capital LLC (TRC) | 1,517 | $60.9K | 0.00% | −3,840−71.7% | Reduced |
| Advisor Group Holdings, Inc. | 1,374 | $55.0K | 0.00% | +149+12.2% | Added |
| State of Wyoming | 1,151 | $46.2K | 0.01% | +610+112.8% | Added |
| Aster Capital Management (DIFC) Ltd | 959 | $38.5K | 0.02% | +959 | New |
| Nisa Investment Advisors, LLC | 924 | $37.1K | 0.00% | +235+34.1% | Added |
| Farther Finance Advisors, LLC | 846 | $34.0K | 0.00% | +62+7.9% | Added |
| Danske Bank A/S | 800 | $32.1K | 0.00% | 00.0% | Unchanged |
| Signaturefd, LLC | 416 | $16.7K | 0.00% | −245−37.1% | Reduced |
| Clearstead Advisors, LLC | 386 | $15.5K | 0.00% | +39+11.2% | Added |
| CWM, LLC | 335 | $13.0K | 0.00% | +98+41.4% | Added |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 276 | $11.1K | 0.00% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 252 | $10.0K | 0.00% | 00.0% | Unchanged |
| United Community Bank | 200 | $8.03K | 0.00% | 00.0% | Unchanged |
| Rockefeller Capital Management L.P. | 200 | $8.03K | 0.00% | +200 | New |
| National Bank of Canada | 200 | $8.03K | 0.00% | −35−14.9% | Reduced |
| GAMMA Investing LLC | 185 | $7.43K | 0.00% | +171+1,221.4% | Added |
| Sterling Capital Management LLC | 184 | $7.39K | 0.00% | 00.0% | Unchanged |
| US Bancorp | 175 | $7.03K | 0.00% | −6−3.3% | Reduced |