Xenon Pharmaceuticals Inc.
XENE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001582313
In the last 90 days, Xenon Pharmaceuticals Inc. insiders filed 0 open-market purchases and 2 sales; 315 institutions reported holding it in 13F filings for Q2 2026, worth $6.10B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q3 2025
Institutional positions in Xenon Pharmaceuticals Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 219
- +15 vs. Q2 2025
- Shares held
- 84.3M
- +1.20M (+1.4%) vs. Q2 2025
- Total value
- $3.39B
- +$783.3M (+30.1%) vs. Q2 2025
- New holders
- 35
- 68 more added
- Sold out
- 20
- 71 more reduced
2 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting XENE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 315 | $6.10B |
| Q1 2026 | 290 | $5.80B |
| Q4 2025 | 245 | $3.78B |
| Q3 2025 | 219 | $3.39B |
| Q2 2025 | 206 | $2.60B |
| Q1 2025 | 206 | $2.58B |
| Q4 2024 | 209 | $2.99B |
| Q3 2024 | 203 | $2.95B |
| Q2 2024 | 213 | $2.89B |
| Q1 2024 | 220 | $3.16B |
| Q4 2023 | 204 | $3.32B |
| Q3 2023 | 181 | $2.10B |
| Q2 2023 | 175 | $2.36B |
| Q1 2023 | 163 | $2.19B |
| Q4 2022 | 159 | $2.38B |
| Q3 2022 | 154 | $2.09B |
| Q2 2022 | 151 | $1.73B |
| Q1 2022 | 132 | $1.50B |
| Q4 2021 | 130 | $1.49B |
| Q3 2021 | 118 | $521.7M |
| Q2 2021 | 103 | $620.0M |
| Q1 2021 | 91 | $590.0M |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Xenon Pharmaceuticals Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Covestor Ltd | 3 | $0 | 0.00% | +3 | New |
| SBI Securities Co., Ltd. | 1 | $40 | 0.00% | +1 | New |
| Tortoise Investment Management, LLC | 2 | $80 | 0.00% | +2 | New |
| Larson Financial Group LLC | 2 | $80 | 0.00% | +2 | New |
| American National Bank | 5 | $201 | 0.00% | 00.0% | Unchanged |
| Bell Investment Advisors, Inc | 11 | $442 | 0.00% | 00.0% | Unchanged |
| Park Place Capital Corp | 16 | $642 | 0.00% | 00.0% | Unchanged |
| Ronald Blue Trust, Inc. | 28 | $1.12K | 0.00% | 00.0% | Unchanged |
| Parkside Financial Bank & Trust | 30 | $1.21K | 0.00% | 00.0% | Unchanged |
| CVA Family Office, LLC | 33 | $1.32K | 0.00% | 00.0% | Unchanged |
| Rossby Financial, LCC | 40 | $1.56K | 0.00% | +40 | New |
| Cape Investment Advisory, Inc. | 39 | $1.57K | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 40 | $1.61K | 0.00% | +14+53.8% | Added |
| Principal Securities, Inc. | 68 | $2.73K | 0.00% | 00.0% | Unchanged |
| J.Safra Asset Management Corp | 87 | $3.49K | 0.00% | 00.0% | Unchanged |
| Rothschild Investment LLC | 115 | $4.62K | 0.00% | −15−11.5% | Reduced |
| SRS Capital Advisors, Inc. | 119 | $4.78K | 0.00% | +119 | New |
| Allworth Financial LP | 126 | $5.06K | 0.00% | +91+260.0% | Added |
| Parallel Advisors, LLC | 147 | $5.90K | 0.00% | +12+8.9% | Added |
| US Bancorp | 175 | $7.03K | 0.00% | −6−3.3% | Reduced |
| Sterling Capital Management LLC | 184 | $7.39K | 0.00% | 00.0% | Unchanged |
| GAMMA Investing LLC | 185 | $7.43K | 0.00% | +171+1,221.4% | Added |
| National Bank of Canada | 200 | $8.03K | 0.00% | −35−14.9% | Reduced |
| United Community Bank | 200 | $8.03K | 0.00% | 00.0% | Unchanged |
| Rockefeller Capital Management L.P. | 200 | $8.03K | 0.00% | +200 | New |
| Daiwa Securities Group Inc. | 252 | $10.0K | 0.00% | 00.0% | Unchanged |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 276 | $11.1K | 0.00% | 00.0% | Unchanged |
| CWM, LLC | 335 | $13.0K | 0.00% | +98+41.4% | Added |
| Clearstead Advisors, LLC | 386 | $15.5K | 0.00% | +39+11.2% | Added |
| Signaturefd, LLC | 416 | $16.7K | 0.00% | −245−37.1% | Reduced |
| Danske Bank A/S | 800 | $32.1K | 0.00% | 00.0% | Unchanged |
| Farther Finance Advisors, LLC | 846 | $34.0K | 0.00% | +62+7.9% | Added |
| Nisa Investment Advisors, LLC | 924 | $37.1K | 0.00% | +235+34.1% | Added |
| Aster Capital Management (DIFC) Ltd | 959 | $38.5K | 0.02% | +959 | New |
| State of Wyoming | 1,151 | $46.2K | 0.01% | +610+112.8% | Added |
| Advisor Group Holdings, Inc. | 1,374 | $55.0K | 0.00% | +149+12.2% | Added |
| Tower Research Capital LLC (TRC) | 1,517 | $60.9K | 0.00% | −3,840−71.7% | Reduced |
| GF Fund Management Co. Ltd. | 1,659 | $66.6K | 0.00% | −293−15.0% | Reduced |
| KBC Group NV | 1,871 | $75.0K | 0.00% | 00.0% | Unchanged |
| IFP Advisors, Inc | 1,908 | $76.6K | 0.00% | +43+2.3% | Added |
| Quarry LP | 2,500 | $100.4K | 0.02% | +500+25.0% | Added |
| Amalgamated Bank | 2,595 | $104.0K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global Investments Co., Ltd. | 2,981 | $119.7K | 0.00% | +17+0.6% | Added |
| Virtus Investment Advisers, Inc. | 3,469 | $139.3K | 0.04% | +602+21.0% | Added |
| Group One Trading, L.P. | 3,556 | $142.8K | 0.00% | −1,097−23.6% | Reduced |
| Northwestern Mutual Wealth Management Co | 5,000 | $200.8K | 0.00% | 00.0% | Unchanged |
| Citizens Financial Group Inc | 5,000 | $200.8K | 0.00% | +5,000 | New |
| EntryPoint Capital, LLC | 5,028 | $201.9K | 0.08% | +5,028 | New |
| Renaissance Technologies LLC | 5,200 | $208.8K | 0.00% | −3,400−39.5% | Reduced |
| Principal Financial Group Inc | 5,818 | $233.6K | 0.00% | +5,818 | New |
| The PNC Financial Services Group, Inc. | 5,899 | $236.8K | 0.00% | +2,437+70.4% | Added |
| Xponance, Inc. | 5,967 | $239.6K | 0.00% | +5,967 | New |
| Inceptionr LLC | 6,322 | $253.8K | 0.06% | +6,322 | New |
| Jump Financial, LLC | 6,500 | $261.0K | 0.00% | −10,491−61.7% | Reduced |
| Ameritas Investment Partners, Inc. | 6,558 | $263.3K | 0.01% | −1,200−15.5% | Reduced |
| Freestone Grove Partners LP | 6,748 | $270.9K | 0.00% | +6,748 | New |
| Great West Life Assurance Co | 7,024 | $274.0K | 0.00% | 00.0% | Unchanged |
| PenderFund Capital Management Ltd. | 6,850 | $275.0K | 0.05% | +6,850 | New |
| SG Americas Securities, LLC | 6,928 | $278.0K | 0.00% | −12,249−63.9% | Reduced |
| Altfest L J & Co Inc | 7,731 | $310.4K | 0.03% | +7,731 | New |
| CIBC Bancorp USA Inc. | 8,100 | $325.2K | 0.00% | +8,100 | New |
| Prudential Financial Inc | 8,850 | $355.3K | 0.00% | −38,905−81.5% | Reduced |
| DRW Securities, LLC | 9,273 | $373.6K | 0.02% | +9,273 | New |
| Allianz Asset Management GmbH | 9,400 | $377.4K | 0.00% | 00.0% | Unchanged |
| Public Employees Retirement Association of Colorado | 10,633 | $427.0K | 0.00% | 00.0% | Unchanged |
| Elmwood Wealth Management, Inc. | 10,907 | $437.9K | 0.16% | +83+0.8% | Added |
| Knott David M Jr | 10,962 | $440.1K | 0.18% | 00.0% | Unchanged |
| Supplemental Annuity Collective Trust of NJ | 11,000 | $441.6K | 0.12% | 00.0% | Unchanged |
| Harbor Capital Advisors, Inc. | 11,218 | $450.0K | 0.03% | −18,818−62.7% | Reduced |
| Advisors Asset Management, Inc. | 11,464 | $460.3K | 0.01% | −741−6.1% | Reduced |
| Schonfeld Strategic Advisors LLC | 12,652 | $508.0K | 0.00% | +2,114+20.1% | Added |
| KLP Kapitalforvaltning AS | 12,800 | $513.9K | 0.00% | 00.0% | Unchanged |
| Creative Planning | 13,210 | $530.4K | 0.00% | +13,210 | New |
| Quantinno Capital Management LP | 13,371 | $536.8K | 0.00% | +13,371 | New |
| CIBC World Markets Inc. | 13,460 | $540.4K | 0.00% | −2,875−17.6% | Reduced |
| China Universal Asset Management Co., Ltd. | 13,515 | $542.6K | 0.04% | −1,897−12.3% | Reduced |
| Legato Capital Management LLC | 14,209 | $570.5K | 0.06% | +4,587+47.7% | Added |
| CenterBook Partners LP | 14,770 | $593.0K | 0.03% | −9,894−40.1% | Reduced |
| Citigroup Inc | 14,870 | $597.0K | 0.00% | −21,420−59.0% | Reduced |
| Brinker Capital Investments, LLC | 14,918 | $598.9K | 0.00% | +20.0% | Added |
| Ensign Peak Advisors, Inc | 15,244 | $612.0K | 0.00% | −10,850−41.6% | Reduced |
| ProShare Advisors LLC | 15,740 | $632.0K | 0.00% | −2,708−14.7% | Reduced |
| Teacher Retirement System of Texas | 16,001 | $642.4K | 0.00% | −1,533−8.7% | Reduced |
| Thrivent Financial for Lutherans | 16,101 | $647.0K | 0.00% | +16,101 | New |
| TD Asset Management Inc | 16,230 | $651.6K | 0.00% | +16,230 | New |
| Natixis Advisors, L.P. | 17,564 | $705.0K | 0.00% | +140+0.8% | Added |
| Two Sigma Advisers, LP | 18,100 | $726.7K | 0.00% | −77,200−81.0% | Reduced |
| Stifel Financial Corp | 18,715 | $751.4K | 0.00% | −1,907−9.2% | Reduced |
| Arizona State Retirement System | 19,290 | $774.5K | 0.00% | +334+1.8% | Added |
| Birchview Capital, LP | 21,000 | $843.1K | 0.64% | 00.0% | Unchanged |
| Police & Firemen's Retirement System of New Jersey | 21,032 | $844.4K | 0.01% | +3,674+21.2% | Added |
| Sanders Morris Harris LLC | 21,500 | $863.2K | 0.11% | +21,500 | New |
| Oxford Asset Management LLP | 22,162 | $889.8K | 0.29% | +1,024+4.8% | Added |
| SEI Investments Co | 22,423 | $900.3K | 0.00% | −300−1.3% | Reduced |
| Assetmark, Inc | 22,566 | $906.0K | 0.00% | +1,316+6.2% | Added |
| Handelsbanken Fonder AB | 22,700 | $911.0K | 0.00% | 00.0% | Unchanged |
| Cinctive Capital Management LP | 23,054 | $925.6K | 0.05% | +23,054 | New |
| Intech Investment Management LLC | 23,086 | $926.9K | 0.01% | −11,226−32.7% | Reduced |
| Man Group plc | 23,119 | $928.2K | 0.00% | −39,229−62.9% | Reduced |
| Rathbone Brothers plc | 23,666 | $950.2K | 0.00% | 00.0% | Unchanged |